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A matter of balance: role of neurexin and neuroligin at the synapse

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@article{d14b6a361bd94cc5b42a757a089523f8,
title = "A matter of balance: role of neurexin and neuroligin at the synapse",
abstract = "Neurexins and neuroligins are synaptic cell adhesion molecules. Neurexins are primary located on the presynaptic membrane, whereas neuroligins are strictly postsynaptic proteins. Since their discovery, the knowledge of neurexins and neuroligins has expanded, implicating them in various neuronal processes, including the differentiation, maturation, stabilization, and plasticity of both inhibitory and excitatory synapses. Here, we review the most recent results regarding the structure and function of these cell adhesion molecules.",
keywords = "Alternative Splicing, Animals, Cell Adhesion Molecules, Neuronal, Child Development Disorders, Pervasive, GABAergic Neurons, Humans, Nerve Tissue Proteins, Protein Conformation, Schizophrenia, Synapses",
author = "Bang, {Marie Louise} and Sylwia Owczarek",
year = "2013",
month = "6",
doi = "10.1007/s11064-013-1029-9",
language = "English",
volume = "38",
pages = "1174--89",
journal = "Neurochemical Research",
issn = "0364-3190",
publisher = "Springer New York LLC",
number = "6",

}

RIS

TY - JOUR

T1 - A matter of balance

T2 - role of neurexin and neuroligin at the synapse

AU - Bang, Marie Louise

AU - Owczarek, Sylwia

PY - 2013/6

Y1 - 2013/6

N2 - Neurexins and neuroligins are synaptic cell adhesion molecules. Neurexins are primary located on the presynaptic membrane, whereas neuroligins are strictly postsynaptic proteins. Since their discovery, the knowledge of neurexins and neuroligins has expanded, implicating them in various neuronal processes, including the differentiation, maturation, stabilization, and plasticity of both inhibitory and excitatory synapses. Here, we review the most recent results regarding the structure and function of these cell adhesion molecules.

AB - Neurexins and neuroligins are synaptic cell adhesion molecules. Neurexins are primary located on the presynaptic membrane, whereas neuroligins are strictly postsynaptic proteins. Since their discovery, the knowledge of neurexins and neuroligins has expanded, implicating them in various neuronal processes, including the differentiation, maturation, stabilization, and plasticity of both inhibitory and excitatory synapses. Here, we review the most recent results regarding the structure and function of these cell adhesion molecules.

KW - Alternative Splicing

KW - Animals

KW - Cell Adhesion Molecules, Neuronal

KW - Child Development Disorders, Pervasive

KW - GABAergic Neurons

KW - Humans

KW - Nerve Tissue Proteins

KW - Protein Conformation

KW - Schizophrenia

KW - Synapses

U2 - 10.1007/s11064-013-1029-9

DO - 10.1007/s11064-013-1029-9

M3 - Journal article

VL - 38

SP - 1174

EP - 1189

JO - Neurochemical Research

JF - Neurochemical Research

SN - 0364-3190

IS - 6

ER -

ID: 42337000