A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation

Marlene D Dalgaard, Nils Weinhold, Daniel Edsgärd, Jeremy David Silver, Tune Hannes Pers, John E Nielsen, Niels Jørgensen, Anders Juul, Thomas Alexander Gerds, Aleksander Giwercman, Yvonne L Giwercman, Gabriella Cohn-Cedermark, Helena E Virtanen, Jorma Toppari, Gedske Daugaard, Thomas S Jensen, Søren Brunak, Ewa Rajpert-De Meyts, Niels E Skakkebæk, Henrik LeffersRamneek Gupta

97 Citations (Scopus)

Abstract

Testicular dysgenesis syndrome (TDS) is a common disease that links testicular germ cell cancer, cryptorchidism and some cases of hypospadias and male infertility with impaired development of the testis. The incidence of these disorders has increased over the last few decades, and testicular cancer now affects 1% of the Danish and Norwegian male population.
Original languageEnglish
JournalJournal of Medical Genetics
Volume49
Issue number1
Pages (from-to)58-65
Number of pages8
ISSN1468-6244
DOIs
Publication statusPublished - 2012

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