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A European Consensus on the Consistent Use of the Term "Keratinocyte Cancer"

Wolfgang G Philipp-Dormston, Lasse R Braathen, Colin A Morton, Merete Haedersdal, Yolanda Gilaberte, Nicole Basset-Seguin, Elena Sotiriou, Stine Regin Wiegell, Piergiacomo Calzavara-Pinton, Thomas Dirschka, Hans Christian Wulf, Günther Hofbauer, Rolf Markus Szeimies

2 Citations (Scopus)

Abstract

Keratinocyte-derived skin cancers comprise basal cell carcinoma, squamous cell carcinoma, its precursor actinic keratosis, and Bowen's disease. Historically, this group of neoplasms has been subsumed under the term non-melanoma skin cancer. However, the term non-melanoma skin cancer can be misleading and lacks precision. Therefore, more precise and reasonable terminology, valuing the relevance of keratinocyte-derived cancer, appears pertinent to meet its clinical and scientific significance. A group of experienced dermato-oncologists initiated a consensus approach to promote the use of the term "keratinocyte cancer" instead of "non-melanoma skin cancer" when referring to carcinomas and their precursors that are derived from keratinocytes. The vote among members of the consensus group indicated unanimous agreement on the consistent use of the term "keratinocyte cancer" instead of "non-melanoma skin cancer". International delegates also voted in favour of the revised terminology. The more precise and, by means of etiopathogenesis, correct term "keratinocyte cancer" should be consistently used for malignancies originated from keratinocytes. This is expected to have a positive impact on patient-physician communication and gives better justice to this important group of keratinocyte-derived cancers.

Original languageEnglish
Article numberadv40601
JournalActa Dermato-Venereologica
Volume104
Pages (from-to)adv40601
ISSN0001-5555
DOIs
Publication statusPublished - 5 Aug 2024

Keywords

  • actinic keratosis
  • basal cell carcinoma
  • consensus
  • keratinocyte cancer
  • non-melanoma skin cancer
  • squamous cell carcinoma

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