A Comparison of Health-related Quality of Life in Chronic Intestinal Failure and End-Stage Kidney Disease: A Cross-Sectional Study

Johanna Eliasson, Louise Bangsgaard Antonsen, Stig Molsted, Ylian Serina Liem, Inge Eidemak, Sille Larsen, Per Sjøgren, Geana Paula Kurita, Palle Bekker Jeppesen*

*Corresponding author for this work

Abstract

BACKGROUND: There is inequal access to treatment and scarce evidence on how the disease burden in chronic intestinal failure (CIF) compares to other chronic nonmalignant types of organ failure. Therefore, we compared the health-related quality of life (HRQOL) of people with CIF with that of people with end-stage kidney disease (ESKD) receiving hemodialysis (HD). These groups were selected for comparison as they have similar treatment characteristics. We hypothesized that people treated with HD and people with CIF had similarly poor HRQOL.

METHODS: HRQOL was evaluated and compared in a cross-sectional study of adult people with CIF and people with ESKD HD at a tertiary hospital in Denmark, using the Short-Form 36 (SF-36).

RESULTS: One hundred forty-one people with CIF and 131 people with ESKD receiving HD were included in the analysis. Both groups reported low scores (<50) for HRQOL on general health, vitality, and role limitation-physical. People with ESKD receiving HD had significantly lower scores than people with CIF regarding physical functioning, general health, and vitality when adjusted for sex and age. No significant difference was found for any other SF-36 domain.

CONCLUSION: HRQOL was similarly and significantly reduced in people with CIF and in people with ESKD receiving HD. People with ESKD receiving HD had significantly poorer HRQOL than people with CIF in some aspects of physical and mental health. Access to home parenteral support treatment varies among countries that typically provide HD, suggesting an inequality in healthcare based on the type of organ failure.

Original languageEnglish
JournalJournal of Parenteral and Enteral Nutrition
Volume48
Issue number2
Pages (from-to)184-191
Number of pages8
ISSN0148-6071
DOIs
Publication statusPublished - Feb 2024

Keywords

  • chronic
  • health-related quality of life
  • intestinal failure
  • kidney failure
  • parenteral nutrition

Fingerprint

Dive into the research topics of 'A Comparison of Health-related Quality of Life in Chronic Intestinal Failure and End-Stage Kidney Disease: A Cross-Sectional Study'. Together they form a unique fingerprint.

Cite this