A comparison of cover letters written by ChatGPT-4 or humans


This study aimed to determine whether Generative Pre-Trained Transformer (GPT)-4 is as good as humans in writing cover letters for scientific papers. In this randomised non-inferiority study, we included two parallel arms consisting of cover letters written by humans and by GPT-4. Each arm had 18 cover letters, which were assessed by three different blinded assessors. The assessors completed a questionnaire in which they had to assess the cover letters with respect to impression, readability, criteria satisfaction, and degree of detail. Subsequently, we performed readability tests with Lix score and Flesch Kincaid grade level. No significant or relevant difference was found on any parameter. We found that GPT-4 was non-inferior at writing cover letters compared to humans. This may be used to streamline cover letters for researchers, providing an equal chance to all researchers for advancement to peer-review
Original languageEnglish
JournalDanish Medical Bulletin (Online)
Issue number11
Publication statusPublished - 2023


  • ChatGPT
  • kunstig intelligens
  • læsbarhed
  • breve
  • forskningsartikler


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