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The Capital Region of Denmark - a part of Copenhagen University Hospital
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A 9-week randomized trial comparing a chronotherapeutic intervention (wake and light therapy) to exercise in major depressive disorder patients treated with duloxetine

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  1. Transcranial pulsed electromagnetic fields for treatment-resistant depression: A multicenter 8-week single-arm cohort study

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  2. Dynamic LED-light versus static LED-light for depressed inpatients: study protocol for a randomised clinical study

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  3. Dynamic LED light versus static LED light for depressed inpatients: results from a randomized feasibility trial

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  4. Per Bech 12.1.1942-9.5.2018 In Memoriam

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The onset of action of antidepressants often takes 4 to 6 weeks. The antidepressant effect of wake therapy (sleep deprivation) comes within hours but carries a risk of relapse. The objective of this study was to investigate whether a new chronotherapeutic intervention combining wake therapy with bright light therapy and sleep time stabilization could induce a rapid and sustained augmentation of response and remission in major depressive disorder.
Original languageEnglish
JournalPrimary Care Companion to C N S Disorders
Volume73
Issue number9
Pages (from-to)1234-42
Number of pages9
ISSN2155-7772
DOIs
Publication statusPublished - 2012

    Research areas

  • Adult, Aged, Antidepressive Agents, Combined Modality Therapy, Denmark, Depressive Disorder, Major, Exercise, Female, Humans, Logistic Models, Male, Middle Aged, Phototherapy, Prospective Studies, Seasons, Single-Blind Method, Sleep Phase Chronotherapy, Thiophenes

ID: 36881539