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The Capital Region of Denmark - a part of Copenhagen University Hospital
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A 10-year follow up of reproductive function in women treated for childhood cancer

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  1. Meditation and mindfulness reduce perceived stress in women with recurrent pregnancy loss: a randomized controlled trial

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  2. Stress and depression among women and men who have experienced recurrent pregnancy loss: focusing on both sexes

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  3. Empathetic application of machine learning may address appropriate utilization of ART

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  4. Futures and fears in the freezer: Danish women's experiences with ovarian tissue cryopreservation and transplantation

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  5. The reproductive microbiome - clinical practice recommendations for fertility specialists

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  1. Selection criteria for assembling a pediatric cancer predisposition syndrome gene panel

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  2. Parenthood among men diagnosed with cancer in childhood and early adulthood: trends over time in a Danish national cohort

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  3. Genomforskningsprojekt påviser TP53-mutation hos en pige med rabdomyosarkom

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  4. Value of flow cytometry for MRD-based relapse prediction in B-cell precursor ALL in a multicenter setting

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Previously, this study group found that female childhood cancer survivors could be at risk of early cessation of fertility. The aim of the present study was to evaluate reproductive function in the same group of survivors 10 years after the initial study. Of the original cohort of 100, 71 were re-examined. Thirty-six survivors reported regular menstrual cycles. When they were compared with 210 controls, they differed significantly in antral follicle count (AFC) (median 15 versus 18, P=0.047) but not in anti-Müllerian hormone (AMH) (median 13.0 versus 17.8pmol/l). Survivors cured with minimal gonadotoxic treatment had significantly higher AMH and AFC compared with survivors cured with either potentially gonadotoxic treatment or treatment including alkylating chemotherapy and ovarian irradiation (20.0, 5.8 and
Original languageEnglish
JournalReproductive BioMedicine Online
Volume27
Issue number2
Pages (from-to)192-200
Number of pages9
ISSN1472-6483
DOIs
Publication statusPublished - Aug 2013

ID: 42460881