(99m) Tc-labelled human serum albumin cannot replace (125) I-labelled human serum albumin to determine plasma volume in patients with liver disease

6 Citations (Scopus)

Abstract

Determination of plasma volume (PV) is important in several clinical situations. Thus, patients with liver disease often have augmented PV as part of their sodium-water retention. This study was undertaken to compare PV determination by two indicators: technetium-labelled human serum albumin ((99m) Tc-HSA) and iodine-labelled human serum albumin ((125) I-HSA), as the former may have advantages at repeated measurements and the latter is the classical gold standard.
Original languageEnglish
JournalClinical Physiology and Functional Imaging
Volume33
Issue number3
Pages (from-to)211-7
Number of pages7
ISSN1475-0961
DOIs
Publication statusPublished - May 2013

Keywords

  • Adult
  • Aged
  • Aged, 80 and over
  • Analysis of Variance
  • Blood Volume Determination
  • Case-Control Studies
  • Female
  • Humans
  • Linear Models
  • Liver Diseases
  • Male
  • Middle Aged
  • Patient Positioning
  • Plasma Volume
  • Predictive Value of Tests
  • Radiopharmaceuticals
  • Reproducibility of Results
  • Serum Albumin, Radio-Iodinated
  • Supine Position
  • Technetium Tc 99m Aggregated Albumin

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