Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

30-day mortality in frail patients undergoing cardiac surgery: the results of the frailty in cardiac surgery (FICS) copenhagen study

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Heart rate increases in liraglutide treated chronic heart failure patients: association with clinical parameters and adverse events

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Relationship Between Invasive Hemodynamics and Liver Function in Advanced Heart Failure

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Atrial fibrillation and anticoagulation in patients with breast cancer

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. A national needs assessment study to determine procedures for simulation-based training in cardiology in Denmark

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Contemporary practice of CRT implantation in scandinavia compared to Europe

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Cyclosporine and COVID-19: Risk or favorable?

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Kontinuerlig glukosemonitorering af patienter med type 1- og type 2-diabetes i dialysebehandling

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Elevated suPAR Is an Independent Risk Marker for Incident Kidney Disease in Acute Medical Patients

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Felodipine and renal function in lung transplantation: A randomized placebo-controlled trial

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Akut dialysekrævende nyresvigt efter massivt indtag af hjemmelavet rabarbergrød

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

Objectives. Typically, patients referred to cardiac surgery are aged. Because EuroSCORE tend to overestimate and STS tend to underestimate the risk of mortality after cardiac surgery, frailty has become interesting as a potential predictor for mortality after cardiac surgery. Therefore, we conducted a study to identify the number of frail patients undergoing cardiac surgery and describe the risk of short-term complications and mortality. Design. In a prospective observational study, we have compared the surgical outcome in frail versus non-frail patients. Patients aged > 65 years and undergoing non-acute cardiac surgery were included. Frailty was assessed using the comprehensive assessment of frailty (CAF) score. The CAF evaluates the patient's physical condition through performing physical tests. Results. 604 patients included, 477 were men and the median age was 73 years (range, 65-90). Twenty-five percent were deemed frail. Frail patients had a four times higher 30-day mortality. Furthermore, frail patients had higher postoperative complication rates of atrial fibrillation, prolonged ventilation, re-operations, renal failure, transfusion requirements, and increased length of stay. Patients who died within 30 days had a significantly higher CAF score than those who survived (p = .039). Based on ROC curves, the area under the curve (AUC) for CAF score was 0.700, EuroSCORE 0.664 and STS score 0.748. Conclusion. Frailty is common in patients undergoing cardiac surgery and carries increased risk of 30-day mortality and postoperative complications. The AUC indicates similar prediction of mortality for CAF score compared to the existing risk scores. Clinical Trials Registration ID: NCT02992587.

Original languageEnglish
JournalScandinavian cardiovascular journal : SCJ
Volume53
Issue number6
Pages (from-to)348-354
Number of pages7
ISSN1401-7431
DOIs
Publication statusPublished - Dec 2019

ID: 58925928