2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: a randomised, multicentre trial

Peter Gillgren; Krzysztof T Drzewiecki; Marianne Niin; Hans P Gullestad; Henrik Hellborg; Eva Månsson-Brahme; Christian Ingvar; Ulrik Ringborg

doi:10.1016/S0140-6736(11)61546-8

2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: a randomised, multicentre trial

Peter Gillgren, Krzysztof T Drzewiecki, Marianne Niin, Hans P Gullestad, Henrik Hellborg, Eva Månsson-Brahme, Christian Ingvar, Ulrik Ringborg

Department of Plastic Surgery and Burns Treatment

190 Citations (Scopus)

Abstract

Optimum surgical resection margins for patients with clinical stage IIA-C cutaneous melanoma thicker than 2 mm are controversial. The aim of the study was to test whether survival was different for a wide local excision margin of 2 cm compared with a 4-cm excision margin.

Original language	English
Journal	Lancet
Volume	378
Issue number	9803
Pages (from-to)	1635-42
Number of pages	8
ISSN	0140-6736
DOIs	https://doi.org/10.1016/S0140-6736(11)61546-8
Publication status	Published - 2011

Keywords

Age Factors
Aged
Female
Follow-Up Studies
Humans
Kaplan-Meier Estimate
Male
Melanoma
Middle Aged
Multivariate Analysis
Neoplasm Recurrence, Local
Prognosis
Sex Factors
Skin Neoplasms
Surgical Flaps

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10.1016/S0140-6736(11)61546-8

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title = "2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: a randomised, multicentre trial",

abstract = "Optimum surgical resection margins for patients with clinical stage IIA-C cutaneous melanoma thicker than 2 mm are controversial. The aim of the study was to test whether survival was different for a wide local excision margin of 2 cm compared with a 4-cm excision margin.",

keywords = "Age Factors, Aged, Female, Follow-Up Studies, Humans, Kaplan-Meier Estimate, Male, Melanoma, Middle Aged, Multivariate Analysis, Neoplasm Recurrence, Local, Prognosis, Sex Factors, Skin Neoplasms, Surgical Flaps",

author = "Peter Gillgren and Drzewiecki, \{Krzysztof T\} and Marianne Niin and Gullestad, \{Hans P\} and Henrik Hellborg and Eva M{\aa}nsson-Brahme and Christian Ingvar and Ulrik Ringborg",

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T1 - 2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: a randomised, multicentre trial

AU - Gillgren, Peter

AU - Drzewiecki, Krzysztof T

AU - Niin, Marianne

AU - Gullestad, Hans P

AU - Hellborg, Henrik

AU - Månsson-Brahme, Eva

AU - Ingvar, Christian

AU - Ringborg, Ulrik

PY - 2011

Y1 - 2011

N2 - Optimum surgical resection margins for patients with clinical stage IIA-C cutaneous melanoma thicker than 2 mm are controversial. The aim of the study was to test whether survival was different for a wide local excision margin of 2 cm compared with a 4-cm excision margin.

AB - Optimum surgical resection margins for patients with clinical stage IIA-C cutaneous melanoma thicker than 2 mm are controversial. The aim of the study was to test whether survival was different for a wide local excision margin of 2 cm compared with a 4-cm excision margin.

KW - Age Factors

KW - Aged

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Kaplan-Meier Estimate

KW - Male

KW - Melanoma

KW - Middle Aged

KW - Multivariate Analysis

KW - Neoplasm Recurrence, Local

KW - Prognosis

KW - Sex Factors

KW - Skin Neoplasms

KW - Surgical Flaps

UR - https://www.scopus.com/pages/publications/80555148140

U2 - 10.1016/S0140-6736(11)61546-8

DO - 10.1016/S0140-6736(11)61546-8

M3 - Journal article

C2 - 22027547

SN - 0140-6736

VL - 378

SP - 1635

EP - 1642

JO - Lancet

JF - Lancet

IS - 9803

ER -

2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: a randomised, multicentre trial

Abstract

Keywords

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