1. trimester-screeningen og FØTOdatabasen

Kasper Gadsbøll; Karin Sundberg; Ida Kirkegaard; Richard Farlie; Lene Sperling; Lars Henning Pedersen; Olav Bjørn Petersen; Finn Stener Jørgensen

doi:10.61409/V12240874

1. trimester-screeningen og FØTOdatabasen

Translated title of the contribution: Combined first trimester screening in Denmark and the Danish Fetal Medicine Database

Kasper Gadsbøll, Karin Sundberg, Ida Kirkegaard, Richard Farlie, Lene Sperling, Lars Henning Pedersen, Olav Bjørn Petersen, Finn Stener Jørgensen^*

^*Corresponding author for this work

Abstract

All pregnant women in Denmark are offered a first-trimester ultrasound screening examination between 11 and 14 weeks of gestation. Additionally, women are offered a risk assessment for foetal chromosomal abnormalities. The main results in this review are that more than 90% of pregnant women attend the first-trimester screening, and of those, 5% receive a high-risk screening result for trisomy 21. The first-trimester screening detects more than 90% of trisomy 21 cases and a large proportion of severe structural malformations. The Danish Fetal Medicine Database (DFMD) was established in 2008-2010. DFMD is a national clinical research and quality database.

Translated title of the contribution	Combined first trimester screening in Denmark and the Danish Fetal Medicine Database
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	187
Issue number	18
ISSN	0041-5782
DOIs	https://doi.org/10.61409/V12240874
Publication status	Published - 28 Apr 2025

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10.61409/V12240874Licence: CC BY-NC-ND

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title = "1. trimester-screeningen og F{\O}TOdatabasen",

abstract = "All pregnant women in Denmark are offered a first-trimester ultrasound screening examination between 11 and 14 weeks of gestation. Additionally, women are offered a risk assessment for foetal chromosomal abnormalities. The main results in this review are that more than 90% of pregnant women attend the first-trimester screening, and of those, 5% receive a high-risk screening result for trisomy 21. The first-trimester screening detects more than 90% of trisomy 21 cases and a large proportion of severe structural malformations. The Danish Fetal Medicine Database (DFMD) was established in 2008-2010. DFMD is a national clinical research and quality database.",

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author = "Kasper Gadsb{\o}ll and Karin Sundberg and Ida Kirkegaard and Richard Farlie and Lene Sperling and Pedersen, {Lars Henning} and Petersen, {Olav Bj{\o}rn} and J{\o}rgensen, {Finn Stener}",

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doi = "10.61409/V12240874",

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T1 - 1. trimester-screeningen og FØTOdatabasen

AU - Gadsbøll, Kasper

AU - Sundberg, Karin

AU - Kirkegaard, Ida

AU - Farlie, Richard

AU - Sperling, Lene

AU - Pedersen, Lars Henning

AU - Petersen, Olav Bjørn

AU - Jørgensen, Finn Stener

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2025/4/28

Y1 - 2025/4/28

N2 - All pregnant women in Denmark are offered a first-trimester ultrasound screening examination between 11 and 14 weeks of gestation. Additionally, women are offered a risk assessment for foetal chromosomal abnormalities. The main results in this review are that more than 90% of pregnant women attend the first-trimester screening, and of those, 5% receive a high-risk screening result for trisomy 21. The first-trimester screening detects more than 90% of trisomy 21 cases and a large proportion of severe structural malformations. The Danish Fetal Medicine Database (DFMD) was established in 2008-2010. DFMD is a national clinical research and quality database.

AB - All pregnant women in Denmark are offered a first-trimester ultrasound screening examination between 11 and 14 weeks of gestation. Additionally, women are offered a risk assessment for foetal chromosomal abnormalities. The main results in this review are that more than 90% of pregnant women attend the first-trimester screening, and of those, 5% receive a high-risk screening result for trisomy 21. The first-trimester screening detects more than 90% of trisomy 21 cases and a large proportion of severe structural malformations. The Danish Fetal Medicine Database (DFMD) was established in 2008-2010. DFMD is a national clinical research and quality database.

KW - Humans

KW - Female

KW - Pregnancy

KW - Denmark/epidemiology

KW - Pregnancy Trimester, First

KW - Databases, Factual

KW - Ultrasonography, Prenatal

KW - Down Syndrome/diagnostic imaging

KW - Prenatal Diagnosis

KW - Risk Assessment

UR - http://www.scopus.com/inward/record.url?scp=105005388872&partnerID=8YFLogxK

U2 - 10.61409/V12240874

DO - 10.61409/V12240874

M3 - Review

C2 - 40358076

SN - 0041-5782

VL - 187

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 18

ER -

1. trimester-screeningen og FØTOdatabasen

Abstract

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