1. trimester-screening for præeklampsi

Iben Riishede; Martin Overgaard; Henriette Ladegård Skov; Puk Sandager; Ann Tabor; Line Rode; Charlotte Kvist Ekelund

doi:10.61409/V11240762

1. trimester-screening for præeklampsi

Translated title of the contribution: First-trimester screening for pre-eclampsia

Iben Riishede, Martin Overgaard, Henriette Ladegård Skov, Puk Sandager, Ann Tabor, Line Rode, Charlotte Kvist Ekelund

1 Citation (Scopus)

Abstract

Pre-eclampsia is a common and serious pregnancy complication. This review describes that low-dose acetylsalicylic acid can reduce the risk of preterm pre-eclampsia in high-risk pregnant women if treatment is started before the 16th week of pregnancy. A new screening algorithm can already, in the first trimester of pregnancy, predict an individual woman's risk of developing pre-eclampsia by combining a series of biophysical and biochemical markers with maternal risk factors. The screening has been validated internationally and in Denmark. In 2025, a national implementation project will be initiated to evaluate the effectiveness of a change in screening strategy in Denmark.

Translated title of the contribution	First-trimester screening for pre-eclampsia
Original language	Danish
Article number	V11240762
Journal	Ugeskrift for Laeger
Volume	187
Issue number	18
ISSN	0041-5782
DOIs	https://doi.org/10.61409/V11240762
Publication status	Published - 28 Apr 2025

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10.61409/V11240762Licence: CC BY-NC-ND

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title = "1. trimester-screening for pr{\ae}eklampsi",

abstract = "Pre-eclampsia is a common and serious pregnancy complication. This review describes that low-dose acetylsalicylic acid can reduce the risk of preterm pre-eclampsia in high-risk pregnant women if treatment is started before the 16th week of pregnancy. A new screening algorithm can already, in the first trimester of pregnancy, predict an individual woman's risk of developing pre-eclampsia by combining a series of biophysical and biochemical markers with maternal risk factors. The screening has been validated internationally and in Denmark. In 2025, a national implementation project will be initiated to evaluate the effectiveness of a change in screening strategy in Denmark.",

keywords = "Humans, Pregnancy, Female, Pre-Eclampsia/diagnosis, Pregnancy Trimester, First, Aspirin/administration \& dosage, Risk Factors, Biomarkers/blood, Mass Screening/methods, Algorithms, Denmark",

author = "Iben Riishede and Martin Overgaard and Skov, \{Henriette Ladeg{\aa}rd\} and Puk Sandager and Ann Tabor and Line Rode and Ekelund, \{Charlotte Kvist\}",

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T1 - 1. trimester-screening for præeklampsi

AU - Riishede, Iben

AU - Overgaard, Martin

AU - Skov, Henriette Ladegård

AU - Sandager, Puk

AU - Tabor, Ann

AU - Rode, Line

AU - Ekelund, Charlotte Kvist

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2025/4/28

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N2 - Pre-eclampsia is a common and serious pregnancy complication. This review describes that low-dose acetylsalicylic acid can reduce the risk of preterm pre-eclampsia in high-risk pregnant women if treatment is started before the 16th week of pregnancy. A new screening algorithm can already, in the first trimester of pregnancy, predict an individual woman's risk of developing pre-eclampsia by combining a series of biophysical and biochemical markers with maternal risk factors. The screening has been validated internationally and in Denmark. In 2025, a national implementation project will be initiated to evaluate the effectiveness of a change in screening strategy in Denmark.

AB - Pre-eclampsia is a common and serious pregnancy complication. This review describes that low-dose acetylsalicylic acid can reduce the risk of preterm pre-eclampsia in high-risk pregnant women if treatment is started before the 16th week of pregnancy. A new screening algorithm can already, in the first trimester of pregnancy, predict an individual woman's risk of developing pre-eclampsia by combining a series of biophysical and biochemical markers with maternal risk factors. The screening has been validated internationally and in Denmark. In 2025, a national implementation project will be initiated to evaluate the effectiveness of a change in screening strategy in Denmark.

KW - Humans

KW - Pregnancy

KW - Female

KW - Pre-Eclampsia/diagnosis

KW - Pregnancy Trimester, First

KW - Aspirin/administration & dosage

KW - Risk Factors

KW - Biomarkers/blood

KW - Mass Screening/methods

KW - Algorithms

KW - Denmark

UR - https://www.scopus.com/pages/publications/105005380209

U2 - 10.61409/V11240762

DO - 10.61409/V11240762

M3 - Review

C2 - 40358075

SN - 0041-5782

VL - 187

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 18

M1 - V11240762

ER -

1. trimester-screening for præeklampsi

Abstract

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