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The Capital Region of Denmark - a part of Copenhagen University Hospital

VIBUS: Effectiveness of family-based intervention in a child and adolescent mental health service for children and adolescents with eating disorders

Project: Types of projectsProject

  • Bentz, Mette (Project Manager, academic)
  • Pagsberg, Anne Katrine (Project Manager, academic)
  • Pedersen, Signe Holm (Project participant)
  • Lundkvist-Houndumadi, Irene (Project participant)
  • Moslet, Ulla (Project participant)
  • Walther, Laila, Landsforeningen mod Spiseforstyrrelser og Selvskade (LMS), Denmark (Working partner)
  • Binderup, Mette Dedenroth, Denmark (Working partner)
  • Baudinet, Julian, South London and Maudsley NHS Foundation Trust, National and Specialist CAMHS, United Kingdom (Working partner)
  • Simic, Mima, South London and Maudsley NHS Foundation Trust, National and Specialist CAMHS, United Kingdom (Working partner)
  • Lauritsen, Maria Louise (Project participant)
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The study aims to characterize a naturalistic cohort of youth with eating disorders (ED) in terms of psychological and psychopathological features. The first choice of evidence-based treatment for ED in youth is outpatient family-based therapy (FBT). However, a subgroup of youth with ED does not respond sufficiently to this treatment, and evidence concerning effective treatment for youth with atypical eating disorders is still lacking. The study will therefore examine the effectiveness; the time patterns of treatment response; and the predictors of treatment outcome in FBT in a longitudinal study with a long-term follow up. It will identify needs and subsequently test potential improvements of standard treatment.

All children and adolescents with eating disorders (ED) aged 7-17 years, treated in the ED unit at CAMHS-CR are invited to participate. The main outcome measure is recovery, defined as maintenance of a healthy body weight; absence of eating disordered behaviors for 3 months; and normal level of concerns around eating, weight, and shape. In addition, a pilot intervention study will investigate the effects of individualized FBT (iFBT), which is based on case formulation and individually tailored adaptations to FBT (add-in modules). We plan to compare the case group receiving iFBT with a comparable group of patients fulfilling the same criteria for case complexity, treated in the same unit before implementation of this intervention (historical control group).

Results (expected):
We will publish all results in relevant scientific journals regardless of whether results are positive, negative or inconclusive. Further, results together with a lay person resume will be accessible via the homepage of the Child and Adolescent Mental Health Centre, Mental Health Services in the Capital Region of Denmark.

Discussion/impact (expected):
The VIBUS project aims to identify needs and subsequently test potential improvements of standard treatment for young persons with eating disorders. It addresses the subgroup of pa-tients, who do not respond favorably to treatment and it addresses the viewpoint expressed by many service users as well as patient organizations that: “one size does not fit all”, when it comes to eating disorders treatment. Currently, no guidelines exist in cases where treat-ment goals are not met by session 20 of family based therapy (FBT). Therefore, the chal-lenge is to understand which child and family characteristics may be associated with non-re-sponse, and whether modifications and/or additions to FBT can help the youths at risk of not responding to FBT. VIBUS meets this overarching aim through a set of work packages (WP).

ID: 61845666