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The Capital Region of Denmark - a part of Copenhagen University Hospital

Danish Database on Refugees with Trauma (DART) - Improving mental health care for trauma-affected refugees

Project: Types of projects

  • Palic-Kapic, Sabina (Project Manager, academic)
  • Carlsson, Jessica Mariana (Project Manager, organisational)
  • Mortensen, Erik Lykke (Project participant)
  • Silove, Derrick , Australia (Project participant)
  • Karstoft, karen-Inge, Veterancenteret, Denmark (Project participant)
  • Benros, Michael Eriksen (Project participant)
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Hypotheses:
• Using the DART, patient subgroups of trauma-affected refugees with different treatment responses to drug-, psychotherapy, and their combination can be identified, including a likely non-responder group.
• The different responses can be predicted by demographic, and post-migratory characteristics, severity and type of traumatic exposure, comorbidity at baseline, as well as treatment- and service-use characteristics.
• Based on the results of our RCT’s, patient characteristics are assumed to be stronger predictors of treatment response than the variations in drug- and psychotherapy across the 5 RCTs.

The aim of the study is to enable development of personalized treatment for trauma-affected refugees in western mental health care. The process has 2 steps. This protocol describes step 1. It sketches only briefly how step 2, will be built into the CTP’s Treatment and Research Integrated Model (TRIM; 4).

The DART study population and methods:
DART data are pooled across CTP’s 5 RCTs. The 5 RCT’s have tested specific hypotheses about drug-, psycho-, and physical therapy. All RCTs were designed to have commonalities, which allow for pooling in a database. Thus, all have identical a) study inclusion criteria, b) primary and secondary outcome measures, c) registration of traumatic exposure, post-migratory difficulties, social service utilization, comorbid diagnoses, demographic information (among many other characteristics) d) as well as e) four identical points of assessment (T1-T4). For more details on inclusion criteria, measures etc. From 2009-2019, 80- 90% of the CTP’s trauma-affected refugee patients have been included in the RCTs. Thus, the full spectrum of cultural, socio-economic, and symptom diversity of a trauma-affected refugee patient population, in a western clinic, is represented. As the trials have run consecutively, with the same inclusion criteria, the DART can be considered as one population, which has been randomized to several treatments.
StatusCurrent
Period01/10/201731/12/2022

ID: 59656692