Research output per year
Research output per year
Personal profile
Expertises
Clinical Oncologist working with Phase 1 Oncology trials since 2005. ESMO board certified in Medical Oncology. Professor in Clinical Oncology with special focus on personalized medicine. Established the Phase 1 Unit at Rigshospitalet in 2005, and established Copenhagen Prospective Personalized Oncology program (CoPPO) in 2013.
Main research areas
Early drug development
Precision Medicine and patient selection based on sequencing platforms
Translational Research with identification of predictive markers
Current research
Principal investigator in > 10 ongoing Phase 1 trials (including first in humans studies). Project leader of CoPPO. Principal supervisor of 6 PH.D.-projects in the field of Precision Medicine, translational research and drug developments. Co-supervisor of a number of other PH.D.-projects.
Potential conflicts of interest
None
External positions
University of Copenhagen
2005 → …
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Collaborations and top research areas from the last five years
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Research output
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Actionable alterations in glioblastoma: Insights from the implementation of genomic profiling as the standard of care from 2016 to 2023
Fougner, V., Urup, T., Poulsen, H. S., Grunnet, K., Westmose, C. Y., Melchior, L. C., Larsen, K. B., Højgaard, M., Spanggaard, I., Belcaid, L., Rohrberg, K. S., Lassen, U., Hasselbalch, B. & Nørøxe, D. S., Feb 2025, In: Neuro-Oncology Practice. 12, 1, p. 34-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Copenhagen Prospective Personalized Oncology (CoPPO) - Impact of comprehensive genomic profiling in more than 2000 patients in a Phase I setting
Belcaid, L., Højgaard, M., Tuxen, I., Spanggaard, I., Lassen, U., Robinson, L., Rossing, M., Bagger, F., Ahlborn, L. B., Schmidt, A. Y., Hasselby, J. P., Santoni-Rugiu, E., Nielsen, F. C., Yde, C. W. & Rohrberg, K., 15 Apr 2025, (E-pub ahead of print) In: Annals of Oncology.Research output: Contribution to journal › Journal article › Research › peer-review
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Degradation fragments of Tau and type IV collagen as serum biomarkers in patients with recurrent glioblastoma treated with nivolumab and bevacizumab
Jensen, C., Maarup, S., Poulsen, H. S., Hasselbalch, B., Karsdal, M., Svane, I. M., Lassen, U. & Willumsen, N., Jun 2025, In: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 27, 6, p. 2761-2767 7 p., e64990.Research output: Contribution to journal › Journal article › Research › peer-review
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HRD status variation in consecutive tumour biopsies in a pan-cancer cohort: a descriptive single-center study including patients from the Phase 1 Unit, Copenhagen University Hospital, Rigshospitalet
Britton, R. D., Alosi, D., Robinson, L., Buhl, I. K., Spanggaard, I., Højgaard, M., Kjeldsen, M. K., Rossing, M., Lassen, U. & Rohrberg, K. S., 20 May 2025, (E-pub ahead of print) In: Cancer genetics. 296-297, p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiomics Identifies Potential Molecular Profiles Associated With Outcomes After BRAF-Targeted Therapy in Patients With BRAF V600E-Mutated Advanced Solid Tumors
Eriksen, M., Hansen, A. M., Nielsen, A. B., Mundt, F., Mann, M., Lassen, U., Ahlborn, L. B., Højgaard, M., Spanggaard, I., Qvortrup, C., Yde, C. W. & Rohrberg, K. S., Mar 2025, In: JCO Precision Oncology. 9, p. e2400266 00266.Research output: Contribution to journal › Journal article › Research › peer-review