Research output per year
Research output per year
Personal profile
Expertises
Molecular biology techniques incl. qPCR, Western Blotting, FISH, Immunoassays, Immunohistochemistry and their application in neuroscience.
Main research areas
Neurodegenerative diseases such as Parkinson’s disease, Multiple System Atrophy, Amyotrophic Lateral Sclerosis.
Current research
Accumulation of abnormal forms of different proteins is a trigger for many neurodegenerative diseases. Recent evidence suggests that much of the downstream neurodegeneration may result from inflammatory responses. I focus on understanding the relationship between the proteins involved in pathogenesis of neurodegenerative diseases and subsequent immune responses towards these proteins. This may help to reveal new targets for neuroprotective interventions.
Potential conflicts of interest
None
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Behavioral and biochemical effects of alcohol withdrawal in female C3H/HeNRj and C57BL/6JRj mice
Tonetto, S., Weikop, P., Brudek, T. & Thomsen, M., 2023, In: Frontiers in Behavioral Neuroscience. 17, p. 1143720Research output: Contribution to journal › Journal article › Research › peer-review
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Alpha-Synuclein Autoimmune Decline in Prodromal Multiple System Atrophy and Parkinson's Disease
Folke, J., Bergholt, E., Pakkenberg, B., Aznar, S. & Brudek, T., 12 Jun 2022, In: International Journal of Molecular Sciences. 23, 12, 6554.Research output: Contribution to journal › Journal article › Research › peer-review
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Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology
Rydbirk, R., Østergaard, O., Folke, J., Hempel, C., DellaValle, B., Andresen, T. L., Løkkegaard, A., Hejl, A-M., Bode, M., Blaabjerg, M., Møller, M., Danielsen, E. H., Salvesen, L., Starhof, C. C., Bech, S., Winge, K., Rungby, J., Pakkenberg, B., Brudek, T., Olsen, J. V., & 1 others, 3 Jun 2022, In: Cellular and Molecular Life Sciences. 79, 6, p. 1-22 22 p., 336.Research output: Contribution to journal › Journal article › Research › peer-review
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Passive Immunization in Alpha-Synuclein Preclinical Animal Models
Folke, J., Ferreira, N., Brudek, T., Borghammer, P. & Van Den Berge, N., 20 Jan 2022, In: Biomolecules. 12, 2, 168.Research output: Contribution to journal › Review › peer-review
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Cerebrospinal fluid and plasma distribution of anti-α-synuclein IgMs and IgGs in multiple system atrophy and Parkinson's disease
Folke, J., Rydbirk, R., Løkkegaard, A., Hejl, A-M., Winge, K., Starhof, C., Salvesen, L., Pedersen, L. Ø., Aznar, S., Pakkenberg, B. & Brudek, T., Jun 2021, In: Parkinsonism & related disorders. 87, p. 98-104 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
9 Citations (Scopus)
Activities
- 1 Lecture and oral contribution
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Distinct autoimmune antibody responses towards TDP-43 in ALS
Tomasz Brudek (Lecturer)
1 Dec 2019 → 4 Dec 2019Activity: Talk or presentation › Lecture and oral contribution