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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2020
  2. Published

    Ovarian and Breast Cancer Risks Associated With Pathogenic Variants in RAD51C and RAD51D

    Yang, X., Song, H., Leslie, G., Engel, C., Hahnen, E., Auber, B., Horváth, J., Kast, K., Niederacher, D., Turnbull, C., Houlston, R., Hanson, H., Loveday, C., Dolinsky, J. S., LaDuca, H., Ramus, S. J., Menon, U., Rosenthal, A. N., Jacobs, I., Gayther, S. A., Dicks, E., Nevanlinna, H., Aittomäki, K., Pelttari, L. M., Ehrencrona, H., Borg, Å., Kvist, A., Rivera, B., Hansen, T. V. O., Djursby, M., Lee, A., Dennis, J., Bowtell, D. D., Traficante, N., Diez, O., Balmaña, J., Gruber, S. B., Chenevix-Trench, G., Investigators, KC., Jensen, A., Kjær, S. K., Høgdall, E., Castéra, L., Garber, J., Janavicius, R., Osorio, A., Golmard, L., Vega, A., Couch, F. J., Robson, M., Gronwald, J., Domchek, S. M., Culver, J. O., de la Hoya, M., Easton, D. F., Foulkes, W. D., Tischkowitz, M., Meindl, A., Schmutzler, R. K., Pharoah, P. D. P. & Antoniou, A. C., 14 Dec 2020, In : National Cancer Institute. Journal (Online). 112, 12, p. 1242-1250 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Nationwide germline whole genome sequencing of 198 consecutive pediatric cancer patients reveals a high incidence of cancer prone syndromes

    Byrjalsen, A., Hansen, T. V. O., Stoltze, U. K., Mehrjouy, M. M., Barnkob, N. M., Hjalgrim, L. L., Mathiasen, R., Lautrup, C. K., Gregersen, P. A., Hasle, H., Wehner, P. S., Tuckuviene, R., Sackett, P. W., Laspiur, A. O., Rossing, M., Marvig, R. L., Tommerup, N., Olsen, T. E., Scheie, D., Gupta, R., Gerdes, A-M., Schmiegelow, K. & Wadt, K., Dec 2020, In : P L o S Genetics. 16, 12, p. e1009231

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Breast cancer survival in Nordic BRCA2 mutation carriers-unconventional association with oestrogen receptor status

    Olafsdottir, E. J., Borg, A., Jensen, M-B., Gerdes, A-M., Johansson, A. L. V., Barkardottir, R. B., Johannsson, O. T., Ejlertsen, B., Sønderstrup, I. M. H., Hovig, E., Lænkholm, A-V., Hansen, T. V. O., Olafsdottir, G. H., Rossing, M., Jonasson, J. G., Sigurdsson, S., Loman, N., Nilsson, M. P., Narod, S. A. & Tryggvadottir, L., Nov 2020, In : British Journal of Cancer. 123, 11, p. 1608-1615 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published
  6. Published

    Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families

    Yang, X., Leslie, G., Doroszuk, A., Schneider, S., Allen, J., Decker, B., Dunning, A. M., Redman, J., Scarth, J., Plaskocinska, I., Luccarini, C., Shah, M., Pooley, K., Dorling, L., Lee, A., Adank, M. A., Adlard, J., Aittomäki, K., Andrulis, I. L., Ang, P., Barwell, J., Bernstein, J. L., Bobolis, K., Borg, Å., Blomqvist, C., Claes, K. B. M., Concannon, P., Cuggia, A., Culver, J. O., Damiola, F., de Pauw, A., Diez, O., Dolinsky, J. S., Domchek, S. M., Engel, C., Evans, D. G., Fostira, F., Garber, J., Golmard, L., Goode, E. L., Gruber, S. B., Hahnen, E., Hake, C., Heikkinen, T., Hurley, J. E., Janavicius, R., Kleibl, Z., Kleiblova, P., Konstantopoulou, I., Kvist, A., Laduca, H., Lee, A. S. G., Lesueur, F., Maher, E. R., Mannermaa, A., Manoukian, S., McFarland, R., McKinnon, W., Meindl, A., Metcalfe, K., Mohd Taib, N. A., Moilanen, J., Nathanson, K. L., Neuhausen, S., Ng, P. S., Nguyen-Dumont, T., Nielsen, S. M., Obermair, F., Offit, K., Olopade, O. I., Ottini, L., Penkert, J., Pylkäs, K., Radice, P., Ramus, S. J., Rudaitis, V., Side, L., Silva-Smith, R., Silvestri, V., Skytte, A-B., Slavin, T., Soukupova, J., Tondini, C., Trainer, A. H., Unzeitig, G., Usha, L., van Overeem Hansen, T., Whitworth, J., Wood, M., Yip, C. H., Yoon, S-Y., Yussuf, A., Zogopoulos, G., Goldgar, D., Hopper, J. L., Chenevix-Trench, G., Pharoah, P., George, S. H. L., Balmaña, J., Houdayer, C., James, P., El-Haffaf, Z., Ehrencrona, H., Janatova, M., Peterlongo, P., Nevanlinna, H., Schmutzler, R., Teo, S-H., Robson, M., Pal, T., Couch, F., Weitzel, J. N., Elliott, A., Southey, M., Winqvist, R., Easton, D. F., Foulkes, W. D., Antoniou, A. C. & Tischkowitz, M., 1 Mar 2020, In : Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 38, 7, p. 674-685 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published
  8. 2019
  9. Published

    Detection of PMS2 Mutations by Screening Hereditary Nonpolyposis Colon Cancer Families from Denmark and Sweden

    Okkels, H., Lagerstedt-Robinsson, K., Wikman, F. P., Hansen, T. V. O., Lolas, I., Lindberg, L. J. & Krarup, H. B., Sep 2019, In : Genetic Testing and Molecular Biomarkers. 23, 9, p. 688-695 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification

    kConFab investigators, Sep 2019, In : Human Mutation. 40, 9, p. 1557-1578 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Exploring the hereditary background of renal cancer in Denmark

    Christensen, M. B., Wadt, K., Jensen, U. B., Lautrup, C. K., Bojesen, A., Krogh, L. N., Overeem Hansen, T. V. & Gerdes, A-M., 1 Apr 2019, In : PLoS One. 14, 4, p. e0215725 e0215725.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    GFP-Fragment Reassembly Screens for the Functional Characterization of Variants of Uncertain Significance in Protein Interaction Domains of the BRCA1 and BRCA2 Genes

    Caleca, L., Colombo, M., van Overeem Hansen, T., Lázaro, C., Manoukian, S., Parsons, M. T., Spurdle, A. B. & Radice, P., 28 Jan 2019, In : Cancers. 11, 2

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2018
  14. Published

    BRCA1 and BRCA2 5' noncoding region variants identified in breast cancer patients alter promoter activity and protein binding

    ENIGMA consortium, Dec 2018, In : Human Mutation. 39, 12, p. 2025-2039 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    MicroRNA dysregulation in adenoid cystic carcinoma of the salivary gland in relation to prognosis and gene fusion status: a cohort study

    Andreasen, S., Tan, Q., Agander, T. K., Hansen, T. V. O., Steiner, P., Bjørndal, K., Høgdall, E., Larsen, S. R., Erentaite, D., Olsen, C. H., Ulhøi, B. P., Heegaard, S., Wessel, I. & Homøe, P., Sep 2018, In : Virchows Archiv : an international journal of pathology. 473, 3, p. 329-340 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Causes of iron overload in blood donors - a clinical study

    Laursen, A. H., Bjerrum, O. W., Friis-Hansen, L., Hansen, T. O., Marott, J. L. & Magnussen, K., 2018, In : Vox Sanguinis. 113, 2, p. 110-119

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Clinical and molecular characterization of BRCA-associated breast cancer: results from the DBCG

    Soenderstrup, I. M. H., Laenkholm, A. V., Jensen, M. B., Eriksen, J. O., Gerdes, A. M., Hansen, T. V. O., Kruse, T. A., Larsen, M. J., Pedersen, I. S., Rossing, M., Thomassen, M. & Ejlertsen, B., 2018, In : Acta oncologica . 57, 1, p. 95-101

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Clinical characteristics and registry-validated extended pedigrees of germline TP53 mutation carriers in Denmark

    Stoltze, U., Skytte, A-B., Roed, H., Hasle, H., Ejlertsen, B., Overeem Hansen, T. V., Schmiegelow, K., Gerdes, A-M. & Wadt, K., 2018, In : P L o S One. 13, 1, p. e0190050

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Genetic Testing and Clinical Management Practices for Variants in Non-BRCA1/2 Breast (and Breast/Ovarian) Cancer Susceptibility Genes: An International Survey by the Evidence-Based Network for the Interpretation of Germline Mutant Alleles (ENIGMA) Clinical Working Group

    Nielsen, S. M., Eccles, D. M., Romero, I. L., Rossing, M., van Overeem Hansen, T., Spurdle, A., De Nicolo, A., Gomez-Garcia, E. B. & ENIGMA consortium, 2018, In : JCO Precision Oncology. 2, p. 1-42 43 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published
  21. Published

    The BRCA1 c. 5096G>A p.Arg1699Gln (R1699Q) intermediate risk variant: breast and ovarian cancer risk estimation and recommendations for clinical management from the ENIGMA consortium

    Moghadasi, S., Meeks, H. D., Vreeswijk, M. P., Janssen, L. A., Borg, Å., Ehrencrona, H., Paulsson-Karlsson, Y., Wappenschmidt, B., Engel, C., Gehrig, A., Arnold, N., Hansen, T. V. O., Thomassen, M., Jensen, U. B., Kruse, T. A., Ejlertsen, B., Gerdes, A-M., Pedersen, I. S., Caputo, S. M., Couch, F., Hallberg, E. J., van den Ouweland, A. M., Collée, M. J., Teugels, E., Adank, M. A., van der Luijt, R. B., Mensenkamp, A. R., Oosterwijk, J. C., Blok, M. J., Janin, N., Claes, K. B., Tucker, K., Viassolo, V., Toland, A. E., Eccles, D. E., Devilee, P., Van Asperen, C. J., Spurdle, A. B., Goldgar, D. E. & García, E. G., 2018, In : Journal of Medical Genetics. 55, 1, p. 15-20

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2017
  23. Published
  24. Published

    Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

    Milne, R. L., Kuchenbaecker, K. B., Michailidou, K., Beesley, J., Kar, S., Lindström, S., Hui, S., Lemaçon, A., Soucy, P., Dennis, J., Jiang, X., Rostamianfar, A., Finucane, H., Bolla, M. K., McGuffog, L., Wang, Q., Aalfs, C. M., Adams, M., Adlard, J., Agata, S., Ahmed, S., Ahsan, H., Aittomäki, K., Al-Ejeh, F., Allen, J., Ambrosone, C. B., Amos, C. I., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Arnold, N., Aronson, K. J., Auber, B., Auer, P. L., Ausems, M. G. E. M., Azzollini, J., Bacot, F., Balmaña, J., Barile, M., Barjhoux, L., Barkardottir, R. B., Bojesen, S. E., Ejlertsen, B., Flyger, H., Gerdes, A-M., Hansen, T. V. O., Lænkholm, A-V., Nielsen, S. F., Nordestgaard, B. G. & ABCTB Investigators, Dec 2017, In : Nature Genetics. 49, 12, p. 1767-1778 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published
  26. Published

    Novel Somatic RET Mutation Questioning the Causality of the RET I852M Germline Sequence Variant in Multiple Endocrine Neoplasia 2A

    Mathiesen, J. S., van Overeem Hansen, T., Rasmussen, Å. K., Hjortshøj, T. D., Kiss, K., Larsen, S. R., Krogh, L. N., Frederiksen, A. L., Hermann, A. P. & Godballe, C., Aug 2017, In : Thyroid : official journal of the American Thyroid Association. 27, 8, p. 1103-1104 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

    Studygroup,Thomas van Overeem Hansen, Anne-Marie Gerdes, members), 1 Jul 2017, In : Journal of the National Cancer Institute. 109, 7, p. djw302

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Incidence and prevalence of multiple endocrine neoplasia 2B in Denmark: a nationwide study

    Mathiesen, J. S., Kroustrup, J. P., Vestergaard, P., Madsen, M., Stochholm, K., Poulsen, P. L., Krogh Rasmussen, Å., Feldt-Rasmussen, U., Schytte, S., Pedersen, H. B., Hahn, C. H., Bentzen, J., Gaustadnes, M., Ørntoft, T. F., Hansen, T. V. O., Nielsen, F. C., Brixen, K., Frederiksen, A. L. & Godballe, C., Jul 2017, In : Endocrine-Related Cancer. 24, 7, p. L39-L42

    Research output: Contribution to journalLetterResearchpeer-review

  29. Published
  30. Published

    Human Papillomavirus-related Carcinoma with Adenoid Cystic-like Features of the Sinonasal Tract: Clinical and Morphological Characterization of 6 New Cases

    Andreasen, S., Bishop, J., Hansen, T. V. O., Westra, W. H., Bilde, A., von Buchwald, C. & Kiss, K., May 2017, In : Histopathology. 70, 6, p. 880-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Phelan, C. M., Kuchenbaecker, K. B., Tyrer, J. P., Kar, S. P., Lawrenson, K., Winham, S. J., Dennis, J., Pirie, A., Riggan, M. J., Chornokur, G., Earp, M. A., Lyra, P. C., Lee, J. M., Coetzee, S., Beesley, J., McGuffog, L., Soucy, P., Dicks, E., Lee, A., Barrowdale, D., Lecarpentier, J., Leslie, G., Aalfs, C. M., Aben, K. K. H., Adams, M., Adlard, J., Andrulis, I. L., Anton-Culver, H., Antonenkova, N., Aravantinos, G., Arnold, N., Arun, B. K., Arver, B., Azzollini, J., Balmaña, J., Banerjee, S. N., Barjhoux, L., Barkardottir, R. B., Bean, Y., Beckmann, M. W., Beeghly-Fadiel, A., Ejlertsen, B., Gerdes, A-M., Hansen, T. V. O., Høgdall, C. K., Høgdall, E., Jensen, A., Kjaer, S. K., Lundvall, L., Nedergaard, L. & AOCS study group, May 2017, In : Nature Genetics. 49, 5, p. 680-691 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Distribution of RET Mutations in Multiple Endocrine Neoplasia 2 in Denmark 1994-2014: A Nationwide Study

    Mathiesen, J. S., Kroustrup, J. P., Vestergaard, P., Stochholm, K., Poulsen, P. L., Rasmussen, Å. K., Feldt-Rasmussen, U., Gaustadnes, M., Ørntoft, T. F., Hansen, T. V. O., Nielsen, F. C., Brixen, K., Godballe, C. & Frederiksen, A. L., 13 Jan 2017, In : Thyroid : official journal of the American Thyroid Association. 27, 2, p. 215-23

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published
  34. Published

    Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3

    Hamdi, Y., Soucy, P., Kuchenbaeker, K. B., Pastinen, T., Droit, A., Lemaçon, A., Adlard, J., Aittomäki, K., Andrulis, I. L., Arason, A., Arnold, N., Arun, B. K., Azzollini, J., Bane, A., Barjhoux, L., Barrowdale, D., Benitez, J., Berthet, P., Blok, M. J., Bobolis, K., Bonadona, V., Bonanni, B., Bradbury, A. R., Brewer, C., Buecher, B., Buys, S. S., Caligo, M. A., Chiquette, J., Chung, W. K., Claes, K. B. M., Daly, M. B., Damiola, F., Davidson, R., De la Hoya, M., De Leeneer, K., Diez, O., Ding, Y. C., Dolcetti, R., Domchek, S. M., Dorfling, C. M., Eccles, D., Eeles, R., Einbeigi, Z., Ejlertsen, B., Engel, C., Gareth Evans, D., Feliubadalo, L., Gerdes, A-M., Hansen, T. V. O., Sønderstrup, I. M. H. & EMBRACE, Jan 2017, In : Breast Cancer Research and Treatment. 161, 1, p. 117-134

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Leukoencephalopathy due to Complex II Deficiency and Bi-Allelic SDHB Mutations: Further Cases and Implications for Genetic Counselling

    Grønborg, S., Darin, N., Miranda, M. J., Damgaard, B., Cayuela, J. A., Oldfors, A., Kollberg, G., Hansen, T. V. O., Ravn, K., Wibrand, F. & Østergaard, E., 2017, In : JIMD Reports. 33, p. 69-77

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2016
  37. Published

    Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

    Rebbeck, T. R., Friebel, T. M., Mitra, N., Wan, F., Chen, S., Andrulis, I. L., Apostolou, P., Arnold, N., Arun, B. K., Barrowdale, D., Benitez, J., Berger, R., Berthet, P., Borg, A., Buys, S. S., Caldes, T., Carter, J., Chiquette, J., Claes, K. B. M., Couch, F. J., Cybulski, C., Daly, M. B., de la Hoya, M., Diez, O., Domchek, S. M., Nathanson, K. L., Durda, K., Ellis, S., Evans, D. G., Foretova, L., Friedman, E., Frost, D., Ganz, P. A., Garber, J., Glendon, G., Godwin, A. K., Greene, M. H., Gronwald, J., Hahnen, E., Hallberg, E., Hamann, U., Hansen, T. V. O., Imyanitov, E. N., Isaacs, C., Jakubowska, A., Janavicius, R., Jaworska-Bieniek, K., John, E. M., Karlan, B. Y., Kaufman, B. & EMBRACE, 11 Nov 2016, In : Breast Cancer Research. 18, 1, p. 112

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published
  39. Published
  40. Published

    BRCA1/BRCA2 founder mutations and cancer risks: impact in the western Danish population

    Nielsen, H. R., Nilbert, M., Petersen, J., Ladelund, S., Thomassen, M., Pedersen, I. S., Hansen, T. V. O., Skytte, A-B., Borg, Å. & Therkildsen, C., Oct 2016, In : Familial Cancer. 15, 4, p. 407-12

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

    Lawrenson, K., Kar, S., McCue, K., Kuchenbaeker, K., Michailidou, K., Tyrer, J., Beesley, J., Ramus, S. J., Li, Q., Delgado, M. K., Lee, J. M., Aittomäki, K., Andrulis, I. L., Anton-Culver, H., Arndt, V., Arun, B. K., Arver, B., Bandera, E. V., Barile, M., Barkardottir, R. B., Barrowdale, D., Beckmann, M. W., Benitez, J., Berchuck, A., Bisogna, M., Bjorge, L., Blomqvist, C., Blot, W., Bogdanova, N., Bojesen, A., Bojesen, S. E., Bolla, M. K., Bonanni, B., Børresen-Dale, A-L., Brauch, H., Brennan, P., Brenner, H., Bruinsma, F., Brunet, J., Buhari, S. A., Burwinkel, B., Butzow, R., Buys, S. S., Cai, Q., Ejlertsen, B., Flyger, H., Hansen, T. V. O., Høgdall, E. V. S., Høgdall, C. K., Kjaer, S. K. & GEMO Study Collaborators, 7 Sep 2016, In : Nature Communications. 7, p. 12675

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Classification of Missense Variants in XRCC2 by Functional Analysis: Implications for Breast Cancer Association Studies

    Hansen, T. V. O., Sep 2016, In : Human Mutation. 37, 9, p. 833

    Research output: Contribution to journalComment/debateResearchpeer-review

  43. Published

    Hereditary breast and ovarian cancer: new genes in confined pathways

    Nielsen, F. C., van Overeem Hansen, T. & Sørensen, C. S., Sep 2016, In : Nature Reviews Cancer. 16, 9, p. 599-612 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

    Zeng, C., Guo, X., Long, J., Kuchenbaecker, K. B., Droit, A., Michailidou, K., Ghoussaini, M., Kar, S., Freeman, A., Hopper, J. L., Milne, R. L., Bolla, M. K., Wang, Q., Dennis, J., Agata, S., Ahmed, S., Aittomäki, K., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Arason, A., Arndt, V., Arun, B. K., Arver, B., Bacot, F., Barrowdale, D., Baynes, C., Beeghly-Fadiel, A., Benitez, J., Bermisheva, M., Blomqvist, C., Blot, W. J., Bogdanova, N. V., Bojesen, S. E., Bonanni, B., Borresen-Dale, A-L., Brand, J. S., Brauch, H., Brennan, P., Brenner, H., Broeks, A., Brüning, T., Burwinkel, B., Buys, S. S., Cai, Q., Caldes, T., Campbell, I., Ejlertsen, B., Flyger, H., Hansen, T. V. O. & EMBRACE, 21 Jun 2016, In : Breast Cancer Research. 18, 1, p. 64

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Combined genetic and splicing analysis of BRCA1 c.[594-2A>C; 641A>G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classification algorithms

    de la Hoya, M., Soukarieh, O., López-Perolio, I., Vega, A., Walker, L. C., van Ierland, Y., Baralle, D., Santamariña, M., Lattimore, V., Wijnen, J., Whiley, P., Blanco, A., Raponi, M., Hauke, J., Wappenschmidt, B., Becker, A., Hansen, T. V. O., Behar, R., Investigators, KC., Niederacher, D., Arnold, N., Dworniczak, B., Steinemann, D., Faust, U., Rubinstein, W., Hulick, P. J., Houdayer, C., Caputo, S. M., Castera, L., Pesaran, T., Chao, E., Brewer, C., Southey, M. C., van Asperen, C. J., Singer, C. F., Sullivan, J., Poplawski, N., Mai, P., Peto, J., Johnson, N., Burwinkel, B., Surowy, H., Bojesen, S. E., Flyger, H., Lindblom, A., Margolin, S., Chang-Claude, J., Rudolph, A., Radice, P., Galastri, L., Olson, J. E., Hallberg, E., Giles, G. G., Milne, R. L., Andrulis, I. L., Glendon, G., Hall, P., Czene, K., Blows, F., Shah, M., Wang, Q., Dennis, J., Michailidou, K., McGuffog, L., Bolla, M. K., Antoniou, A. C., Easton, D. F., Couch, F. J., Tavtigian, S., Vreeswijk, M. P., Parsons, M., Meeks, H. D., Martins, A., Goldgar, D. E. & Spurdle, A. B., 1 Jun 2016, In : Human Molecular Genetics. 25, 11, p. 2256-2268 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Disease pattern in Danish patients with Peutz-Jeghers syndrome

    Jelsig, A. M., Qvist, N., Sunde, L., Brusgaard, K., Hansen, T. V. O., Wikman, F. P., Nielsen, C. B., Nielsen, I. K., Gerdes, A. M., Bojesen, A. & Ousager, L. B., May 2016, In : International Journal of Colorectal Disease. 31, 5, p. 997-1004

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer

    Hollestelle, A., van der Baan, F. H., Berchuck, A., Johnatty, S. E., Aben, K. K., Agnarsson, B. A., Aittomäki, K., Alducci, E., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Antoniou, A. C., Apicella, C., Arndt, V., Arnold, N., Arun, B. K., Arver, B., Ashworth, A., Baglietto, L., Balleine, R., Bandera, E. V., Barrowdale, D., Bean, Y. T., Beckmann, L., Beckmann, M. W., Benitez, J., Berger, A., Berger, R., Beuselinck, B., Bisogna, M., Bjorge, L., Blomqvist, C., Bogdanova, N. V., Bojesen, A., Bojesen, S. E., Bolla, M. K., Bonanni, B., Brand, J. S., Ejlertsen, B., Gerdes, A-M., Hansen, T. V. O., Høgdall, C. K., Høgdall, E., Jensen, A., Kjaer, S. K., Lundvall, L., Nielsen, F. C., Nielsen, S. F., Nordestgaard, B. G., Weischer, M. & Ovarian Cancer Association Consortium, Breast Cancer Association Consortium, and Consortium of Modifiers of BRCA1 and BRCA2, May 2016, In : Gynecologic Oncology. 141, 2, p. 386-401

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

    Couch, F. J., Kuchenbaecker, K. B., Michailidou, K., Mendoza-Fandino, G. A., Nord, S., Lilyquist, J., Olswold, C., Hallberg, E., Agata, S., Ahsan, H., Aittomäki, K., Ambrosone, C., Andrulis, I. L., Anton-Culver, H., Arndt, V., Arun, B. K., Arver, B., Barile, M., Barkardottir, R. B., Barrowdale, D., Beckmann, L., Beckmann, M. W., Benitez, J., Blank, S. V., Blomqvist, C., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Bonanni, B., Brauch, H., Brenner, H., Burwinkel, B., Buys, S. S., Caldes, T., Caligo, M. A., Canzian, F., Carpenter, J., Chang-Claude, J., Chanock, S. J., Chung, W. K., Claes, K. B. M., Cox, A., Cross, S. S., Cunningham, J. M., Czene, K., Daly, M. B., Damiola, F., Darabi, H., de la Hoya, M., Devilee, P., Diez, O., Ding, Y. C., Dolcetti, R., Domchek, S. M., Dorfling, C. M., Dos-Santos-Silva, I., Dumont, M., Dunning, A. M., Eccles, D. M., Ehrencrona, H., Ekici, A. B., Eliassen, H., Ellis, S., Fasching, P. A., Figueroa, J., Flesch-Janys, D., Försti, A., Fostira, F., Foulkes, W. D., Friebel, T., Friedman, E., Frost, D., Gabrielson, M., Gammon, M. D., Ganz, P. A., Gapstur, S. M., Garber, J., Gaudet, M. M., Gayther, S. A., Gerdes, A-M., Ghoussaini, M., Giles, G. G., Glendon, G., Godwin, A. K., Goldberg, M. S., Goldgar, D. E., González-Neira, A., Greene, M. H., Gronwald, J., Guénel, P., Gunter, M., Haeberle, L., Haiman, C. A., Hamann, U., Hansen, T. V. O., Hart, S., Healey, S., Heikkinen, T., Henderson, B. E., Herzog, J., Hogervorst, F. B. L., Hollestelle, A., Hooning, M. J., Hoover, R. N., Hopper, J. L., Humphreys, K., Hunter, D. J., Huzarski, T., Imyanitov, E. N., Isaacs, C., Jakubowska, A., James, P., Janavicius, R., Jensen, U. B., John, E. M., Jones, M., Kabisch, M., Kar, S., Karlan, B. Y., Khan, S., Khaw, K-T., Kibriya, M. G., Knight, J. A., Ko, Y-D., Konstantopoulou, I., Kosma, V-M., Kristensen, V., Kwong, A., Laitman, Y., Lambrechts, D., Lazaro, C., Lee, E., Le Marchand, L., Lester, J., Lindblom, A., Lindor, N., Lindstrom, S., Liu, J., Long, J., Lubinski, J., Mai, P. L., Makalic, E., Malone, K. E., Mannermaa, A., Manoukian, S., Margolin, S., Marme, F., Martens, J. W. M., McGuffog, L., Meindl, A., Miller, A., Milne, R. L., Miron, P., Montagna, M., Mazoyer, S., Mulligan, A. M., Muranen, T. A., Nathanson, K. L., Neuhausen, S. L., Nevanlinna, H., Nordestgaard, B. G., Nussbaum, R. L., Offit, K., Olah, E., Olopade, O. I., Olson, J. E., Osorio, A., Park, S. K., Peeters, P. H., Peissel, B., Peterlongo, P., Peto, J., Phelan, C. M., Pilarski, R., Poppe, B., Pylkäs, K., Radice, P., Rahman, N., Rantala, J., Rappaport, C., Rennert, G., Richardson, A., Robson, M., Romieu, I., Rudolph, A., Rutgers, E. J., Sanchez, M-J., Santella, R. M., Sawyer, E. J., Schmidt, D. F., Schmidt, M. K., Schmutzler, R. K., Schumacher, F., Scott, R., Senter, L., Sharma, P., Simard, J., Singer, C. F., Sinilnikova, O. M., Soucy, P., Southey, M., Steinemann, D., Stenmark-Askmalm, M., Stoppa-Lyonnet, D., Swerdlow, A., Szabo, C. I., Tamimi, R., Tapper, W., Teixeira, M. R., Teo, S-H., Terry, M. B., Thomassen, M., Thompson, D., Tihomirova, L., Toland, A. E., Tollenaar, R. A. E. M., Tomlinson, I., Truong, T., Tsimiklis, H., Teulé, A., Tumino, R., Tung, N., Turnbull, C., Ursin, G., van Deurzen, C. H. M., van Rensburg, E. J., Varon-Mateeva, R., Wang, Z., Wang-Gohrke, S., Weiderpass, E., Weitzel, J. N., Whittemore, A., Wildiers, H., Winqvist, R., Yang, X. R., Yannoukakos, D., Yao, S., Zamora, M. P., Zheng, W., Hall, P., Kraft, P., Vachon, C., Slager, S., Chenevix-Trench, G., Pharoah, P. D. P., Monteiro, A. A. N., García-Closas, M., Easton, D. F. & Antoniou, A. C., 27 Apr 2016, In : Nature Communications. 7, p. 11375

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170

    Dunning, A. M., Michailidou, K., Kuchenbaecker, K. B., Thompson, D., French, J. D., Beesley, J., Healey, C. S., Kar, S., Pooley, K. A., Lopez-Knowles, E., Dicks, E., Barrowdale, D., Sinnott-Armstrong, N. A., Sallari, R. C., Hillman, K. M., Kaufmann, S., Sivakumaran, H., Moradi Marjaneh, M., Lee, J. S., Hills, M., Jarosz, M., Drury, S., Canisius, S., Bolla, M. K., Dennis, J., Wang, Q., Hopper, J. L., Southey, M. C., Broeks, A., Schmidt, M. K., Lophatananon, A., Muir, K., Beckmann, M. W., Fasching, P. A., Dos-Santos-Silva, I., Peto, J., Sawyer, E. J., Tomlinson, I., Burwinkel, B., Marme, F., Guénel, P., Truong, T., Bojesen, S. E., Flyger, H., González-Neira, A., Perez, J. I. A., Anton-Culver, H., Ejlertsen, B., Hansen, T. V. O., Bojesen, S. E. & EMBRACE, Apr 2016, In : Nature Genetics. 48, 4, p. 374-86 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2

    Silvestri, V., Barrowdale, D., Mulligan, A. M., Neuhausen, S. L., Fox, S., Karlan, B. Y., Mitchell, G., James, P., Thull, D. L., Zorn, K. K., Carter, N. J., Nathanson, K. L., Domchek, S. M., Rebbeck, T. R., Ramus, S. J., Nussbaum, R. L., Olopade, O. I., Rantala, J., Yoon, S-Y., Caligo, M. A., Spugnesi, L., Bojesen, A., Pedersen, I. S., Thomassen, M., Jensen, U. B., Toland, A. E., Senter, L., Andrulis, I. L., Glendon, G., Hulick, P. J., Imyanitov, E. N., Greene, M. H., Mai, P. L., Singer, C. F., Rappaport-Fuerhauser, C., Kramer, G., Vijai, J., Offit, K., Robson, M., Lincoln, A., Jacobs, L., Machackova, E., Foretova, L., Navratilova, M., Vasickova, P., Couch, F. J., Hallberg, E., Gerdes, A-M., Ejlertsen, B., Hansen, T. V. O. & kConFab Investigators, 9 Feb 2016, In : Breast Cancer Research. 18, 1, p. 15

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

    Meeks, H. D., Song, H., Michailidou, K., Bolla, M. K., Dennis, J., Wang, Q., Barrowdale, D., Frost, D., McGuffog, L., Ellis, S., Feng, B., Buys, S. S., Hopper, J. L., Southey, M. C., Tesoriero, A., James, P. A., Bruinsma, F., Campbell, I. G., Broeks, A., Schmidt, M. K., Hogervorst, F. B. L., Beckman, M. W., Fasching, P. A., Fletcher, O., Johnson, N., Sawyer, E. J., Riboli, E., Banerjee, S., Menon, U., Tomlinson, I., Burwinkel, B., Hamann, U., Marme, F., Rudolph, A., Janavicius, R., Tihomirova, L., Tung, N., Garber, J., Cramer, D., Terry, K. L., Poole, E. M., Tworoger, S. S., Dorfling, C. M., Bojesen, S. E., Flyger, H., Gerdes, A-M., Hansen, T. V. O., Kjaer, S. K., Hogdall, C., Hogdall, E. & EMBRACE, Feb 2016, In : Journal of the National Cancer Institute. 108, 2, p. djv315

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published
  53. Published

    Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

    Vigorito, E., Kuchenbaecker, K. B., Beesley, J., Adlard, J., Agnarsson, B. A., Andrulis, I. L., Arun, B. K., Barjhoux, L., Belotti, M., Benitez, J., Berger, A., Bojesen, A., Bonanni, B., Brewer, C., Caldes, T., Caligo, M. A., Campbell, I., Chan, S. B., Claes, K. B. M., Cohn, D. E., Cook, J., Daly, M. B., Damiola, F., Davidson, R., Pauw, A. D., Delnatte, C., Diez, O., Domchek, S. M., Dumont, M., Durda, K., Dworniczak, B., Easton, D. F., Eccles, D., Edwinsdotter Ardnor, C., Eeles, R., Ejlertsen, B., Ellis, S., Evans, D. G., Feliubadalo, L., Fostira, F., Foulkes, W. D., Friedman, E., Frost, D., Gaddam, P., Ganz, P. A., Garber, J., Garcia-Barberan, V., Gauthier-Villars, M., Gehrig, A., Gerdes, A-M., Giraud, S., Godwin, A. K., Goldgar, D. E., Hake, C. R., Hansen, T. V. O., Healey, S., Hodgson, S., Hogervorst, F. B. L., Houdayer, C., Hulick, P. J., Imyanitov, E. N., Isaacs, C., Izatt, L., Izquierdo, A., Jacobs, L., Jakubowska, A., Janavicius, R., Jaworska-Bieniek, K., Jensen, U. B., John, E. M., Vijai, J., Karlan, B. Y., Kast, K., Investigators, KC., Khan, S., Kwong, A., Laitman, Y., Lester, J., Lesueur, F., Liljegren, A., Lubinski, J., Mai, P. L., Manoukian, S., Mazoyer, S., Meindl, A., Mensenkamp, A. R., Montagna, M., Nathanson, K. L., Neuhausen, S. L., Nevanlinna, H., Niederacher, D., Olah, E., Olopade, O. I., Ong, K-R., Osorio, A., Park, S. K., Paulsson-Karlsson, Y., Pedersen, I. S., Peissel, B., Peterlongo, P., Pfeiler, G., Phelan, C. M., Piedmonte, M., Poppe, B., Pujana, M. A., Radice, P., Rennert, G., Rodriguez, G. C., Rookus, M. A., Ross, E. A., Schmutzler, R. K., Simard, J., Singer, C. F., Slavin, T. P., Soucy, P., Southey, M., Steinemann, D., Stoppa-Lyonnet, D., Sukiennicki, G., Sutter, C., Szabo, C. I., Tea, M-K., Teixeira, M. R., Teo, S-H., Terry, M. B., Thomassen, M., Tibiletti, M. G., Tihomirova, L., Tognazzo, S., van Rensburg, E. J., Varesco, L., Varon-Mateeva, R., Vratimos, A., Weitzel, J. N., McGuffog, L., Kirk, J., Toland, A. E., Hamann, U., Lindor, N., Ramus, S. J., Greene, M. H., Couch, F. J., Offit, K., Pharoah, P. D. P., Chenevix-Trench, G. & Antoniou, A. C., 2016, In : P L o S One. 11, 7, p. e0158801

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Identification of eight novel SDHB, SDHC, SDHD germline variants in Danish pheochromocytoma/paraganglioma patients

    Bennedbæk, M., Rossing, M., Rasmussen, Å. K., Gerdes, A-M., Skytte, A-B., Jensen, U. B., Nielsen, F. C. & Hansen, T. V. O., 2016, In : Hereditary Cancer in Clinical Practice. 14, p. 13

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 2015
  56. Published

    Germline RAD51B truncating mutation in a family with cutaneous melanoma

    Wadt, K. A. W., Aoude, L. G., Golmard, L., Hansen, T. V. O., Sastre-Garau, X., Hayward, N. K. & Gerdes, A-M., Jun 2015, In : Familial Cancer. 14, 2, p. 337-40 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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