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Personal profile

Expertises

Genomics; Register epidemiology; Disease trajectories; Systems biology; Animal modeling, Drug discovery; Epigenetics; Metabolomics.

Main research areas

The main research objectives are to identify genomic and environmental risk factors and disease mechanisms and to link these to life-long disease trajectories of mental disorders using population-based registers and biobanks.

Current research

The main projects include population-based studies and combined into four categories: (a) Identification and risk estimates of pathogenic copy-number variants, (b) Genomics predictors of disease trajectories, (c) Genomics-deduced molecular disease mechanisms, (d) Genealogy-deduced heritabilities and co-heritabilities of mental disorders, and (d) Development of biomarkers of genomic risk factors and of mental disorders.

Potential conflicts of interest

Thomas Werge has obtained grants, collaborated and published on common research programs as well as acted as lecturer and consultant to H. Lundbeck A/S

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Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • Polygenic profiles define aspects of clinical heterogeneity in attention deficit hyperactivity disorder

    LaBianca, S., Brikell, I., Helenius, D., Loughnan, R., Mefford, J., Palmer, C. E., Walker, R., Gådin, J. R., Krebs, M., Appadurai, V., Vaez, M., Agerbo, E., Pedersen, M. G., Børglum, A. D., Hougaard, D. M., Mors, O., Nordentoft, M., Mortensen, P. B., Kendler, K. S., Jernigan, T. L., & 7 othersGeschwind, D. H., Ingason, A., Dahl, A. W., Zaitlen, N., Dalsgaard, S., Werge, T. M. & Schork, A. J., Feb 2024, In: Nature Genetics. 56, 2, p. 234-244 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Population genomics of post-glacial western Eurasia

    Allentoft, M. E., Sikora, M., Refoyo-Martínez, A., Irving-Pease, E. K., Fischer, A., Barrie, W., Ingason, A., Stenderup, J., Sjögren, K-G., Pearson, A., Sousa da Mota, B., Schulz Paulsson, B., Halgren, A., Macleod, R., Jørkov, M. L. S., Demeter, F., Sørensen, L., Nielsen, P. O., Henriksen, R. A., Vimala, T., & 144 othersMcColl, H., Margaryan, A., Ilardo, M., Vaughn, A., Fischer Mortensen, M., Nielsen, A. B., Ulfeldt Hede, M., Johannsen, N. N., Rasmussen, P., Vinner, L., Renaud, G., Stern, A., Jensen, T. Z. T., Scorrano, G., Schroeder, H., Lysdahl, P., Ramsøe, A. D., Skorobogatov, A., Rosengren, A., Ruter, A., Outram, A., Timoshenko, A. A., Buzhilova, A., Coppa, A., Zubova, A., Silva, A. M., Hansen, A. J., Gromov, A., Logvin, A., Gotfredsen, A. B., Henning Nielsen, B., González-Rabanal, B., Lalueza-Fox, C., McKenzie, C. J., Gaunitz, C., Blasco, C., Liesau, C., Martinez-Labarga, C., Pozdnyakov, D. V., Cuenca-Solana, D., Lordkipanidze, D. O., En'shin, D., Salazar-García, D. C., Price, T. D., Borić, D., Kostyleva, E., Veselovskaya, E. V., Usmanova, E. R., Cappellini, E., Brinch Petersen, E., Kannegaard, E., Radina, F., Eylem Yediay, F., Duday, H., Gutiérrez-Zugasti, I., Merts, I., Potekhina, I., Shevnina, I., Altinkaya, I., Guilaine, J., Hansen, J., Aura Tortosa, J. E., Zilhão, J., Vega, J., Buck Pedersen, K., Tunia, K., Zhao, L., Mylnikova, L. N., Larsson, L., Metz, L., Yepiskoposyan, L., Pedersen, L., Sarti, L., Orlando, L., Slimak, L., Klassen, L., Blank, M., González-Morales, M., Silvestrini, M., Vretemark, M., Nesterova, M. S., Rykun, M., Rolfo, M. F., Szmyt, M., Przybyła, M., Calattini, M., Sablin, M., Dobisíková, M., Meldgaard, M., Johansen, M., Berezina, N., Card, N., Saveliev, N. A., Poshekhonova, O., Rickards, O., Lozovskaya, O. V., Gábor, O., Uldum, O. C., Aurino, P., Kosintsev, P., Courtaud, P., Ríos, P., Mortensen, P., Lotz, P., Persson, P., Bangsgaard, P., de Barros Damgaard, P., Vang Petersen, P., Martinez, P. P., Włodarczak, P., Smolyaninov, R. V., Maring, R., Menduiña, R., Badalyan, R., Iversen, R., Turin, R., Vasilyev, S., Wåhlin, S., Borutskaya, S., Skochina, S., Sørensen, S. A., Andersen, S. H., Jørgensen, T., Serikov, Y. B., Molodin, V. I., Smrcka, V., Merts, V., Appadurai, V., Moiseyev, V., Magnusson, Y., Kjær, K. H., Lynnerup, N., Lawson, D. J., Sudmant, P. H., Rasmussen, S., Korneliussen, T. S., Durbin, R., Nielsen, R., Delaneau, O., Werge, T., Racimo, F., Kristiansen, K., Willerslev, E. & Schork, A. J., Jan 2024, In: Nature. 625, 7994, p. 301-311 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Potential causal association between gut microbiome and posttraumatic stress disorder

    Psychiatric Genomics Consortium Posttraumatic Stress Disorder Working Group & Werge, T. M., 31 Jan 2024, In: Translational psychiatry. 14, 1, p. 67 67.

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Publisher Correction: Population genomics of post-glacial western Eurasia

    Allentoft, M. E., Sikora, M., Refoyo-Martínez, A., Irving-Pease, E. K., Fischer, A., Barrie, W., Ingason, A., Stenderup, J., Sjögren, K-G., Pearson, A., Sousa da Mota, B., Schulz Paulsson, B., Halgren, A., Macleod, R., Jørkov, M. L. S., Demeter, F., Sørensen, L., Nielsen, P. O., Henriksen, R. A., Vimala, T., & 144 othersMcColl, H., Margaryan, A., Ilardo, M., Vaughn, A., Fischer Mortensen, M., Nielsen, A. B., Ulfeldt Hede, M., Johannsen, N. N., Rasmussen, P., Vinner, L., Renaud, G., Stern, A., Jensen, T. Z. T., Scorrano, G., Schroeder, H., Lysdahl, P., Ramsøe, A. D., Skorobogatov, A., Rosengren, A., Ruter, A., Outram, A., Timoshenko, A. A., Buzhilova, A., Coppa, A., Zubova, A., Silva, A. M., Hansen, A. J., Gromov, A., Logvin, A., Gotfredsen, A. B., Henning Nielsen, B., González-Rabanal, B., Lalueza-Fox, C., McKenzie, C. J., Gaunitz, C., Blasco, C., Liesau, C., Martinez-Labarga, C., Pozdnyakov, D. V., Cuenca-Solana, D., Lordkipanidze, D. O., En'shin, D., Salazar-García, D. C., Price, T. D., Borić, D., Kostyleva, E., Veselovskaya, E. V., Usmanova, E. R., Cappellini, E., Brinch Petersen, E., Kannegaard, E., Radina, F., Eylem Yediay, F., Duday, H., Gutiérrez-Zugasti, I., Merts, I., Potekhina, I., Shevnina, I., Altinkaya, I., Guilaine, J., Hansen, J., Aura Tortosa, J. E., Zilhão, J., Vega, J., Buck Pedersen, K., Tunia, K., Zhao, L., Mylnikova, L. N., Larsson, L., Metz, L., Yepiskoposyan, L., Pedersen, L., Sarti, L., Orlando, L., Slimak, L., Klassen, L., Blank, M., González-Morales, M., Silvestrini, M., Vretemark, M., Nesterova, M. S., Rykun, M., Rolfo, M. F., Szmyt, M., Przybyła, M., Calattini, M., Sablin, M., Dobisíková, M., Meldgaard, M., Johansen, M., Berezina, N., Card, N., Saveliev, N. A., Poshekhonova, O., Rickards, O., Lozovskaya, O. V., Gábor, O., Uldum, O. C., Aurino, P., Kosintsev, P., Courtaud, P., Ríos, P., Mortensen, P., Lotz, P., Persson, P., Bangsgaard, P., de Barros Damgaard, P., Vang Petersen, P., Martinez, P. P., Włodarczak, P., Smolyaninov, R. V., Maring, R., Menduiña, R., Badalyan, R., Iversen, R., Turin, R., Vasilyev, S., Wåhlin, S., Borutskaya, S., Skochina, S., Sørensen, S. A., Andersen, S. H., Jørgensen, T., Serikov, Y. B., Molodin, V. I., Smrcka, V., Merts, V., Appadurai, V., Moiseyev, V., Magnusson, Y., Kjær, K. H., Lynnerup, N., Lawson, D. J., Sudmant, P. H., Rasmussen, S., Korneliussen, T. S., Durbin, R., Nielsen, R., Delaneau, O., Werge, T., Racimo, F., Kristiansen, K., Willerslev, E. & Ingason, A., Feb 2024, In: Nature. 626, 7997, p. E3

    Research output: Contribution to journalJournal articleResearchpeer-review

  • The selection landscape and genetic legacy of ancient Eurasians

    Irving-Pease, E. K., Refoyo-Martínez, A., Barrie, W., Ingason, A., Pearson, A., Fischer, A., Sjögren, K-G., Halgren, A. S., Macleod, R., Demeter, F., Henriksen, R. A., Vimala, T., McColl, H., Vaughn, A. H., Speidel, L., Stern, A. J., Scorrano, G., Ramsøe, A., Schork, A. J., Rosengren, A., & 14 othersZhao, L., Kristiansen, K., Iversen, A. K. N., Fugger, L., Sudmant, P. H., Lawson, D. J., Durbin, R., Korneliussen, T., Werge, T., Allentoft, M. E., Sikora, M., Nielsen, R., Racimo, F. & Willerslev, E., 10 Jan 2024, In: Nature. 625, 7994, p. 312-320 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review