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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2022
  2. Published

    New insights into the genetic etiology of Alzheimer's disease and related dementias

    Bellenguez, C., Küçükali, F., Jansen, I. E., Kleineidam, L., Moreno-Grau, S., Amin, N., Naj, A. C., Campos-Martin, R., Grenier-Boley, B., Andrade, V., Holmans, P. A., Boland, A., Damotte, V., van der Lee, S. J., Costa, M. R., Kuulasmaa, T., Yang, Q., de Rojas, I., Bis, J. C., Yaqub, A. & 39 others, Prokic, I., Chapuis, J., Ahmad, S., Giedraitis, V., Aarsland, D., Garcia-Gonzalez, P., Abdelnour, C., Alarcón-Martín, E., Alcolea, D., Alegret, M., Alvarez, I., Álvarez, V., Armstrong, N. J., Tsolaki, A., Antúnez, C., Appollonio, I., Arcaro, M., Archetti, S., Pastor, A. A., Arosio, B., Athanasiu, L., Bailly, H., Banaj, N., Baquero, M., Barral, S., Nielsen, S. F., Nordestgaard, B. G., Thomassen, J. Q., Tybjærg-Hansen, A., Frikke-Schmidt, R., EADB, GR@CE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC & CHARGE, Apr 2022, In: Nature Genetics. 54, 4, p. 412-436 25 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. 2021
  4. Published

    Asthma and COPD versus phenotypic traits: Toward precision medicine in chronic airway disease

    Vedel-Krogh, S., Nielsen, S. F., Nordestgaard, B. G., Lange, P. & Vestbo, J., Sep 2021, In: Respiratory medicine. 186, p. 106529 106529.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment

    Morra, A., Escala-Garcia, M., Beesley, J., Keeman, R., Canisius, S., Ahearn, T. U., Andrulis, I. L., Anton-Culver, H., Arndt, V., Auer, P. L., Augustinsson, A., Beane Freeman, L. E., Becher, H., Beckmann, M. W., Behrens, S., Bojesen, S. E., Bolla, M. K., Brenner, H., Brüning, T., Buys, S. S. & 31 others, Caan, B., Campa, D., Canzian, F., Castelao, J. E., Chang-Claude, J., Chanock, S. J., Cheng, T-Y. D., Clarke, C. L., Colonna, S. V., Couch, F. J., Cox, A., Cross, S. S., Czene, K., Daly, M. B., Dennis, J., Dörk, T., Dossus, L., Dunning, A. M., Dwek, M., Eccles, D. M., Ekici, A. B., Eliassen, A. H., Eriksson, M., Evans, D. G., Fasching, P. A., Flyger, H., Fritschi, L., Gago-Dominguez, M., Nielsen, S. F., Nordestgaard, B. G. & NBCS Collaborators, 18 Aug 2021, In: Breast Cancer Research. 23, 1, p. 86 1 p., 86.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer

    UKGPCS collaborators, Jun 2021, In: Prostate Cancer and Prostatic Diseases. 24, 2, p. 532-541 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published
  8. Published

    Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

    Surendran, P., Feofanova, E. V., Lahrouchi, N., Ntalla, I., Karthikeyan, S., Cook, J., Chen, L., Mifsud, B., Yao, C., Kraja, A. T., Cartwright, J. H., Hellwege, J. N., Giri, A., Tragante, V., Thorleifsson, G., Liu, D. J., Prins, B. P., Stewart, I. D., Cabrera, C. P., Eales, J. M. & 31 others, Akbarov, A., Auer, P. L., Bielak, L. F., Bis, J. C., Braithwaite, V. S., Brody, J. A., Daw, E. W., Warren, H. R., Drenos, F., Nielsen, S. F., Faul, J. D., Fauman, E. B., Fava, C., Ferreira, T., Foley, C. N., Franceschini, N., Gao, H., Giannakopoulou, O., Giulianini, F., Gudbjartsson, D. F., Guo, X., Harris, S. E., Havulinna, A. S., Bork-Jensen, J., Hansen, T., Jørgensen, M. E., Linneberg, A., Rasmussen, K. L., Skaaby, T., Nordestgaard, B. G. & LifeLines Cohort study, May 2021, In: Nature Genetics. 53, 5, p. 762

    Research output: Contribution to journalComment/debatepeer-review

  9. Published

    KLK3 SNP-SNP interactions for prediction of prostate cancer aggressiveness

    UKGPCS collaborators, 29 Apr 2021, In: Scientific Reports. 11, 1, p. 9264 9264.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Polygenic hazard score is associated with prostate cancer in multi-ethnic populations

    UKGPCS collaborators, 23 Feb 2021, In: Nature Communications. 12, 1, p. 1236 1236.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers

    Johnson, N., Maguire, S., Morra, A., Kapoor, P. M., Tomczyk, K., Jones, M. E., Schoemaker, M. J., Gilham, C., Bolla, M. K., Wang, Q., Dennis, J., Ahearn, T. U., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Aronson, K. J., Augustinsson, A., Baynes, C., Freeman, L. E. B. & 31 others, Beckmann, M. W., Benitez, J., Bermisheva, M., Blomqvist, C., Boeckx, B., Bogdanova, N. V., Bojesen, S. E., Brauch, H., Brenner, H., Burwinkel, B., Campa, D., Canzian, F., Castelao, J. E., Chanock, S. J., Chenevix-Trench, G., Clarke, C. L., Conroy, D. M., Couch, F. J., Cox, A., Cross, S. S., Czene, K., Dörk, T., Eliassen, A. H., Engel, C., Evans, D. G., Fasching, P. A., Figueroa, J., Flyger, H., Nielsen, S. F., Nordestgaard, B. G. & NBCS Collaborators, 16 Feb 2021, In: British Journal of Cancer. 124, 4, p. 842-854 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Complement C3 and allergic asthma: A cohort study of the general population

    Vedel-Krogh, S., Rasmussen, K. L., Nordestgaard, B. G. & Nielsen, S. F., 1 Feb 2021, In: European Respiratory Journal. 57, 2, 2000645.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published
  14. Published

    Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

    Conti, D. V., Darst, B. F., Moss, L. C., Saunders, E. J., Sheng, X., Chou, A., Schumacher, F. R., Olama, A. A. A., Benlloch, S., Dadaev, T., Brook, M. N., Sahimi, A., Hoffmann, T. J., Takahashi, A., Matsuda, K., Momozawa, Y., Fujita, M., Muir, K., Lophatananon, A., Wan, P. & 211 others, Le Marchand, L., Wilkens, L. R., Stevens, V. L., Gapstur, S. M., Carter, B. D., Schleutker, J., Tammela, T. L. J., Sipeky, C., Auvinen, A., Giles, G. G., Southey, M. C., MacInnis, R. J., Cybulski, C., Wokołorczyk, D., Lubiński, J., Neal, D. E., Donovan, J. L., Hamdy, F. C., Martin, R. M., Nordestgaard, B. G., Nielsen, S. F., Weischer, M., Bojesen, S. E., Røder, M. A., Iversen, P., Batra, J., Chambers, S., Moya, L., Horvath, L., Clements, J. A., Tilley, W., Risbridger, G. P., Gronberg, H., Aly, M., Szulkin, R., Eklund, M., Nordström, T., Pashayan, N., Dunning, A. M., Ghoussaini, M., Travis, R. C., Key, T. J., Riboli, E., Park, J. Y., Sellers, T. A., Lin, H-Y., Albanes, D., Weinstein, S. J., Mucci, L. A., Giovannucci, E., Lindstrom, S., Kraft, P., Hunter, D. J., Penney, K. L., Turman, C., Tangen, C. M., Goodman, P. J., Thompson, I. M., Hamilton, R. J., Fleshner, N. E., Finelli, A., Parent, M-É., Stanford, J. L., Ostrander, E. A., Geybels, M. S., Koutros, S., Freeman, L. E. B., Stampfer, M., Wolk, A., Håkansson, N., Andriole, G. L., Hoover, R. N., Machiela, M. J., Sørensen, K. D., Borre, M., Blot, W. J., Zheng, W., Yeboah, E. D., Mensah, J. E., Lu, Y-J., Zhang, H-W., Feng, N., Mao, X., Wu, Y., Zhao, S-C., Sun, Z., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., West, C. M. L., Burnet, N., Barnett, G., Maier, C., Schnoeller, T., Luedeke, M., Kibel, A. S., Drake, B. F., Cussenot, O., Cancel-Tassin, G., Menegaux, F., Truong, T., Koudou, Y. A., John, E. M., Grindedal, E. M., Maehle, L., Khaw, K-T., Ingles, S. A., Stern, M. C., Vega, A., Gómez-Caamaño, A., Fachal, L., Rosenstein, B. S., Kerns, S. L., Ostrer, H., Teixeira, M. R., Paulo, P., Brandão, A., Watya, S., Lubwama, A., Bensen, J. T., Fontham, E. T. H., Mohler, J., Taylor, J. A., Kogevinas, M., Llorca, J., Castaño-Vinyals, G., Cannon-Albright, L., Teerlink, C. C., Huff, C. D., Strom, S. S., Multigner, L., Blanchet, P., Brureau, L., Kaneva, R., Slavov, C., Mitev, V., Leach, R. J., Weaver, B., Brenner, H., Cuk, K., Holleczek, B., Saum, K-U., Klein, E. A., Hsing, A. W., Kittles, R. A., Murphy, A. B., Logothetis, C. J., Kim, J., Neuhausen, S. L., Steele, L., Ding, Y. C., Isaacs, W. B., Nemesure, B., Hennis, A. J. M., Carpten, J., Pandha, H., Michael, A., De Ruyck, K., De Meerleer, G., Ost, P., Xu, J., Razack, A., Lim, J., Teo, S-H., Newcomb, L. F., Lin, D. W., Fowke, J. H., Neslund-Dudas, C., Rybicki, B. A., Gamulin, M., Lessel, D., Kulis, T., Usmani, N., Singhal, S., Parliament, M., Claessens, F., Joniau, S., Van den Broeck, T., Gago-Dominguez, M., Castelao, J. E., Martinez, M. E., Larkin, S., Townsend, P. A., Aukim-Hastie, C., Bush, W. S., Aldrich, M. C., Crawford, D. C., Srivastava, S., Cullen, J. C., Petrovics, G., Casey, G., Roobol, M. J., Jenster, G., van Schaik, R. H. N., Hu, J. J., Sanderson, M., Varma, R., McKean-Cowdin, R., Torres, M., Mancuso, N., Berndt, S. I., Van Den Eeden, S. K., Easton, D. F., Chanock, S. J., Cook, M. B., Wiklund, F., Nakagawa, H., Witte, J. S., Eeles, R. A., Kote-Jarai, Z. & Haiman, C. A., Jan 2021, In: Nature Genetics. 53, 1, p. 65-75 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  15. 2020
  16. Published

    The CHEK2 Variant C.349A>G Is Associated with Prostate Cancer Risk and Carriers Share a Common Ancestor

    Brandão, A., Paulo, P., Maia, S., Pinheiro, M., Peixoto, A., Cardoso, M., Silva, M. P., Santos, C., Eeles, R. A., Kote-Jarai, Z., Muir, K., Ukgpcs Collaborators, Schleutker, J., Wang, Y., Pashayan, N., Batra, J., Apcb BioResource, Grönberg, H., Neal, D. E., Nordestgaard, B. G. & 45 others, Tangen, C. M., Southey, M. C., Wolk, A., Albanes, D., Haiman, C. A., Travis, R. C., Stanford, J. L., Mucci, L. A., West, C. M. L., Nielsen, S. F., Kibel, A. S., Cussenot, O., Berndt, S. I., Koutros, S., Sørensen, K. D., Cybulski, C., Grindedal, E. M., Park, J. Y., Ingles, S. A., Maier, C., Hamilton, R. J., Rosenstein, B. S., Vega, A., The Impact Study Steering Committee And Collaborators, Kogevinas, M., Wiklund, F., Penney, K. L., Brenner, H., John, E. M., Kaneva, R., Logothetis, C. J., Neuhausen, S. L., Ruyck, K. D., Razack, A., Newcomb, L. F., Canary Pass Investigators, Lessel, D., Usmani, N., Claessens, F., Gago-Dominguez, M., Townsend, P. A., Roobol, M. J., The Profile Study Steering Committee, The Practical Consortium & Teixeira, M. R., 4 Nov 2020, In: Cancers. 12, 11, p. 1-17 17 p., 3254.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

    Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviour, CHD Exome+ consortium, 25 Oct 2020, In: Molecular Psychiatry. 25, 10, p. 2392-2409 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Dickkopf-1 overexpression in vitro nominates candidate blood biomarkers relating to Alzheimer's Disease pathology

    Shi, L., Winchester, L. M., Liu, B. Y., Killick, R., Ribe, E. M., Westwood, S., Baird, A. L., Buckley, N. J., Hong, S., Dobricic, V., Kilpert, F., Franke, A., Kiddle, S., Sattlecker, M., Dobson, R., Cuadrado, A., Hye, A., Ashton, N. J., Morgan, A. R., Bos, I. & 47 others, Vos, S. J. B., Ten Kate, M., Scheltens, P., Vandenberghe, R., Gabel, S., Meersmans, K., Engelborghs, S., De Roeck, E. E., Sleegers, K., Frisoni, G. B., Blin, O., Richardson, J. C., Bordet, R., Molinuevo, J. L., Rami, L., Wallin, A., Kettunen, P., Tsolaki, M., Verhey, F., Lleó, A., Alcolea, D., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Johannsen, P., Teunissen, C. E., Freund-Levi, Y., Frölich, L., Legido-Quigley, C., Barkhof, F., Blennow, K., Rasmussen, K. L., Nordestgaard, B. G., Frikke-Schmidt, R., Nielsen, S. F., Soininen, H., Vellas, B., Kloszewska, I., Mecocci, P., Zetterberg, H., Morgan, B. P., Streffer, J., Visser, P. J., Bertram, L., Nevado-Holgado, A. J. & Lovestone, S., 2020, In: Journal of Alzheimer's Disease. 77, 3, p. 1353-1368 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

    Surendran, P., Feofanova, E. V., Lahrouchi, N., Ntalla, I., Karthikeyan, S., Cook, J., Chen, L., Mifsud, B., Yao, C., Kraja, A. T., Cartwright, J. H., Hellwege, J. N., Giri, A., Tragante, V., Thorleifsson, G., Liu, D. J., Prins, B. P., Stewart, I. D., Cabrera, C. P., Eales, J. M. & 31 others, Akbarov, A., Auer, P. L., Bielak, L. F., Bis, J. C., Braithwaite, V. S., Brody, J. A., Daw, E. W., Warren, H. R., Drenos, F., Nielsen, S. F., Faul, J. D., Fauman, E. B., Fava, C., Ferreira, T., Foley, C. N., Franceschini, N., Gao, H., Giannakopoulou, O., Giulianini, F., Gudbjartsson, D. F., Guo, X., Harris, S. E., Havulinna, A. S., Bork-Jensen, J., Hansen, T., Jørgensen, M. E., Linneberg, A., Rasmussen, K. L., Skaaby, T., Nordestgaard, B. G. & LifeLines Cohort study, 2020, In: Nature Genetics. 52, 12, p. 1314-1332 19 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. 2019
  21. Published

    Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Turcot, V., Lu, Y., Highland, H. M., Schurmann, C., Justice, A. E., Fine, R. S., Bradfield, J. P., Esko, T., Giri, A., Graff, M., Guo, X., Hendricks, A. E., Karaderi, T., Lempradl, A., Locke, A. E., Mahajan, A., Marouli, E., Sivapalaratnam, S., Young, K. L., Alfred, T. & 31 others, Feitosa, M. F., Masca, N. G. D., Manning, A. K., Medina-Gomez, C., Mudgal, P., Ng, M. C. Y., Reiner, A. P., Vedantam, S., Willems, S. M., Winkler, T. W., Abecasis, G., Bang, L. E., Benn, M., Bork-Jensen, J., Friedrich, N., Frikke-Schmidt, R., Hansen, T., Jensen, G. B., Jørgensen, M. E., Jørgensen, T., Kamstrup, P. R., Linneberg, A., Nielsen, S. F., Nordestgaard, B. G., Pers, T. H., Petersen, E. R. B., Thuesen, B. H., Tybjaerg-Hansen, A., Varbo, A., Vestergaard, H. & CHD Exome+ Consortium, Jul 2019, In: Nature Genetics. 51, 7, p. 1191-1192 2 p.

    Research output: Contribution to journalComment/debatepeer-review

  22. Published

    Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis

    Breast Cancer Association Consortium , Jun 2019, In: International Journal of Epidemiology. p. 795-806

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use

    CHD Exome+ Consortium, Jun 2019, In: Biological Psychiatry.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Genome-wide association study of germline variants and breast cancer-specific mortality

    NBCS Collaborators, Mar 2019, In: British Journal of Cancer. 120, 6, p. 647-657 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (Nature Genetics, (2018), 50, 7, (928-936), 10.1038/s41588-018-0142-8)

    Schumacher, F. R., Olama, A. A. A., Berndt, S. I., Benlloch, S., Ahmed, M., Saunders, E. J., Dadaev, T., Leongamornlert, D., Anokian, E., Cieza-Borrella, C., Goh, C., Brook, M. N., Sheng, X., Fachal, L., Dennis, J., Tyrer, J., Muir, K., Lophatananon, A., Stevens, V. L., Gapstur, S. M. & 31 others, Carter, B. D., Tangen, C. M., Goodman, P. J., Thompson, I. M., Batra, J., Chambers, S., Moya, L., Clements, J., Horvath, L., Tilley, W., Risbridger, G. P., Gronberg, H., Aly, M., Nordström, T., Pharoah, P., Pashayan, N., Schleutker, J., Tammela, T. L. J., Sipeky, C., Auvinen, A., Albanes, D., Weinstein, S., Wolk, A., Håkansson, N., Nordestgaard, B. G., Nielsen, S. F., Weischer, M., Bisbjerg, R., Røder, M. A., Iversen, P. & Profile Study, Feb 2019, In: Nature Genetics. 51, 2, p. 363 1 p.

    Research output: Contribution to journalComment/debatepeer-review

  26. Published

    Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    ABCTB Investigators, 3 Jan 2019, In: American Journal of Human Genetics. 104, 1, p. 21-34 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Identification and Replication of Six Loci Associated With Gallstone Disease

    Gellert-Kristensen, H., Dalila, N., Nielsen, S. F., Nordestgaard, B. G., Tybjaerg-Hansen, A. & Stender, S., 2019, In: Hepatology (Baltimore, Md.). 70, 2, p. 597-609 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. 2018
  29. Published
  30. Published
  31. Published

    Association of LPA variants with risk of coronary disease and the implications for lipoprotein(a)-lowering therapies: A mendelian randomization analysis

    European Prospective Investigation Into Cancer and Nutritioon-Cardiovascular Disease (EPIC-CVD) Consortium, 1 Jul 2018, In: JAMA Cardiology. 3, 7, p. 619-627 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

    NBCS Collaborators, Jul 2018, In: Nature Genetics. 50, 7, p. 968-978 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published
  34. Published

    Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

    Profile Study, 11 Jun 2018, In: Nature Genetics. 50, p. 928-36

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants

    PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium, 11 Jun 2018, In: Nature Communications. 9, 1, p. 2256

    Research output: Contribution to journalJournal articlepeer-review

  36. Published
  37. Published

    Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Turcot, V., Lu, Y., Highland, H. M., Schurmann, C., Justice, A. E., Fine, R. S., Bradfield, J. P., Esko, T., Giri, A., Graff, M., Guo, X., Hendricks, A. E., Karaderi, T., Lempradl, A., Locke, A. E., Mahajan, A., Marouli, E., Sivapalaratnam, S., Young, K. L., Alfred, T. & 31 others, Feitosa, M. F., Masca, N. G. D., Manning, A. K., Medina-Gomez, C., Mudgal, P., Ng, M. C. Y., Reiner, A. P., Vedantam, S., Willems, S. M., Winkler, T. W., Abecasis, G., Bang, L. E., Benn, M., Bork-Jensen, J., Friedrich, N., Frikke-Schmidt, R., Hansen, T., Jensen, G. B., Jørgensen, M. E., Jørgensen, T., Kamstrup, P. R., Linneberg, A., Nielsen, S. F., Nordestgaard, B. G., Pers, T. H., Petersen, E. R. B., Thuesen, B. H., Tybjaerg-Hansen, A., Varbo, A., Vestergaard, H. & CHD Exome+ Consortium, May 2018, In: Nature Genetics. 50, 5, p. 765-766 2 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

    Ghoussaini, M., Edwards, S. L., Michailidou, K., Nord, S., Cowper-Sal Lari, R., Desai, K., Kar, S., Hillman, K. M., Kaufmann, S., Glubb, D. M., Beesley, J., Dennis, J., Bolla, M. K., Wang, Q., Dicks, E., Guo, Q., Schmidt, M. K., Shah, M., Luben, R., Brown, J. & 191 others, Czene, K., Darabi, H., Eriksson, M., Klevebring, D., Bojesen, S. E., Nordestgaard, B. G., Nielsen, S. F., Flyger, H., Lambrechts, D., Thienpont, B., Neven, P., Wildiers, H., Broeks, A., Van't Veer, L. J., Rutgers, E. J. T., Couch, F. J., Olson, J. E., Hallberg, E., Vachon, C., Chang-Claude, J., Rudolph, A., Seibold, P., Flesch-Janys, D., Peto, J., Dos-Santos-Silva, I., Gibson, L., Nevanlinna, H., Muranen, T. A., Aittomäki, K., Blomqvist, C., Hall, P., Li, J., Liu, J., Humphreys, K., Kang, D., Choi, J-Y., Park, S. K., Noh, D-Y., Matsuo, K., Ito, H., Iwata, H., Yatabe, Y., Guénel, P., Truong, T., Menegaux, F., Sanchez, M., Burwinkel, B., Marme, F., Schneeweiss, A., Sohn, C., Wu, A. H., Tseng, C-C., Van Den Berg, D., Stram, D. O., Benitez, J., Pilar Zamora, M., Perez, J. I. A., Menéndez, P., Shu, X-O., Lu, W., Gao, Y-T., Cai, Q., Cox, A., Cross, S. S., Reed, M. W. R., Andrulis, I. L., Knight, J. A., Glendon, G., Tchatchou, S., Sawyer, E. J., Tomlinson, I., Kerin, M. J., Miller, N., Haiman, C. A., Henderson, B. E., Schumacher, F., Le Marchand, L., Lindblom, A., Margolin, S., Teo, S. H., Yip, C. H., Lee, D. S. C., Wong, T. Y., Hooning, M. J., Martens, J. W. M., Collée, J. M., van Deurzen, C. H. M., Hopper, J. L., Southey, M. C., Tsimiklis, H., Kapuscinski, M. K., Shen, C-Y., Wu, P-E., Yu, J-C., Chen, S-T., Alnæs, G. G., Borresen-Dale, A-L., Giles, G. G., Milne, R. L., McLean, C., Muir, K., Lophatananon, A., Stewart-Brown, S., Siriwanarangsan, P., Hartman, M., Miao, H., Buhari, S. A. B. S., Teo, Y. Y., Fasching, P. A., Haeberle, L., Ekici, A. B., Beckmann, M. W., Brenner, H., Dieffenbach, A. K., Arndt, V., Stegmaier, C., Swerdlow, A., Ashworth, A., Orr, N., Schoemaker, M. J., García-Closas, M., Figueroa, J., Chanock, S. J., Lissowska, J., Simard, J., Goldberg, M. S., Labrèche, F., Dumont, M., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Brauch, H., Brüning, T., Koto, Y-D., Radice, P., Peterlongo, P., Bonanni, B., Volorio, S., Dörk, T., Bogdanova, N. V., Helbig, S., Mannermaa, A., Kataja, V., Kosma, V-M., Hartikainen, J. M., Devilee, P., Tollenaar, R. A. E. M., Seynaeve, C., Van Asperen, C. J., Jakubowska, A., Lubinski, J., Jaworska-Bieniek, K., Durda, K., Slager, S., Toland, A. E., Ambrosone, C. B., Yannoukakos, D., Sangrajrang, S., Gaborieau, V., Brennan, P., McKay, J., Hamann, U., Torres, D., Zheng, W., Long, J., Anton-Culver, H., Neuhausen, S. L., Luccarini, C., Baynes, C., Ahmed, S., Maranian, M., Healey, C. S., González-Neira, A., Pita, G., Rosario Alonso, M., Álvarez, N., Herrero, D., Tessier, D. C., Vincent, D., Bacot, F., de Santiago, I., Carroll, J., Caldas, C., Brown, M. A., Lupien, M., Kristensen, V. N., Pharoah, P. D. P., Chenevix-Trench, G., French, J. D., Easton, D. F. & Dunning, A. M., 10 Apr 2018

    Research output: Other contributionResearch

  39. Published

    Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

    Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P. & 31 others, Flannick, J., Grarup, N., Trubetskoy, V. V., Kravic, J., Kim, Y. J., Rybin, D. V., Yaghootkar, H., Müller-Nurasyid, M., Meidtner, K., Li-Gao, R., Varga, T. V., Marten, J., Li, J., Smith, A. V., An, P., Ligthart, S., Gustafsson, S., Malerba, G., Afzal, S., Bang, L. B., Bork-Jensen, J., Tybjærg-Hansen, A., Jørgensen, M. E., Jørgensen, T., Linneberg, A., Nielsen, S. F., Rode, L., Varbo, A., Rosengren, A. H., Nordestgaard, B. G. & ExomeBP Consortium, Apr 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts

    Seibert, T. M., Fan, C. C., Wang, Y., Zuber, V., Karunamuni, R., Parsons, J. K., Eeles, R. A., Easton, D. F., Kote-Jarai, ZS., Al Olama, A. A., Garcia, S. B., Muir, K., Grönberg, H., Wiklund, F., Aly, M., Schleutker, J., Sipeky, C., Tammela, T. L., Nordestgaard, B. G., Nielsen, S. F. & 31 others, Weischer, M., Bisbjerg, R., Røder, M. A., Iversen, P., Key, T. J., Travis, R. C., Neal, D. E., Donovan, J. L., Hamdy, F. C., Pharoah, P., Pashayan, N., Khaw, K-T., Maier, C., Vogel, W., Luedeke, M., Herkommer, K., Kibel, A. S., Cybulski, C., Wokolorczyk, D., Kluzniak, W., Cannon-Albright, L., Brenner, H., Cuk, K., Saum, K-U., Park, J. Y., Sellers, T. A., Slavov, C., Kaneva, R., Mitev, V., Batra, J. & PRACTICAL Consortium*, 10 Jan 2018, In: BMJ. 360, p. j5757

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Turcot, V., Lu, Y., Highland, H. M., Schurmann, C., Justice, A. E., Fine, R. S., Bradfield, J. P., Esko, T., Giri, A., Graff, M., Guo, X., Hendricks, A. E., Karaderi, T., Lempradl, A., Locke, A. E., Mahajan, A., Marouli, E., Sivapalaratnam, S., Young, K. L., Alfred, T. & 31 others, Feitosa, M. F., Masca, N. G. D., Manning, A. K., Medina-Gomez, C., Mudgal, P., Ng, M. C. Y., Reiner, A. P., Vedantam, S., Willems, S. M., Winkler, T. W., Abecasis, G., Aben, K. K., Alam, D. S., Alharthi, S. E., Bang, L. E., Benn, M., Bork-Jensen, J., Frikke-Schmidt, R., Jensen, G. B., Jørgensen, M. E., Jørgensen, T., Kamstrup, P. R., Linneberg, A., Nielsen, S. F., Nordestgaard, B. G., Pers, T. H., Thuesen, B. H., Tybjaerg-Hansen, A., Varbo, A., Vestergaard, H. & CHD Exome+ Consortium, Jan 2018, In: Nature Genetics. 50, 1, p. 26-41 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. 2017
  43. Published

    Body mass index and breast cancer survival: a Mendelian randomization analysis

    Guo, Q., Burgess, S., Turman, C., Bolla, M. K., Wang, Q., Lush, M., Abraham, J., Aittomäki, K., Andrulis, I. L., Apicella, C., Arndt, V., Barrdahl, M., Benitez, J., Berg, C. D., Blomqvist, C., Bojesen, S. E., Bonanni, B., Brand, J. S., Brenner, H., Broeks, A. & 31 others, Burwinkel, B., Caldas, C., Campa, D., Canzian, F., Chang-Claude, J., Chanock, S. J., Chin, S-F., Couch, F. J., Cox, A., Cross, S. S., Cybulski, C., Czene, K., Darabi, H., Devilee, P., Diver, W. R., Dunning, A. M., Earl, H. M., Eccles, D. M., Ekici, A. B., Eriksson, M., Evans, D. G., Fasching, P. A., Figueroa, J., Flesch-Janys, D., Flyger, H., Gapstur, S. M., Gaudet, M. M., Giles, G. G., Nielsen, S. F., Nordestgaard, B. G. & kConFab/AOCS Investigators, 1 Dec 2017, In: International Journal of Epidemiology. 46, 6, p. 1814-1822 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

    Milne, R. L., Kuchenbaecker, K. B., Michailidou, K., Beesley, J., Kar, S., Lindström, S., Hui, S., Lemaçon, A., Soucy, P., Dennis, J., Jiang, X., Rostamianfar, A., Finucane, H., Bolla, M. K., McGuffog, L., Wang, Q., Aalfs, C. M., Adams, M., Adlard, J., Agata, S. & 31 others, Ahmed, S., Ahsan, H., Aittomäki, K., Al-Ejeh, F., Allen, J., Ambrosone, C. B., Amos, C. I., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Arnold, N., Aronson, K. J., Auber, B., Auer, P. L., Ausems, M. G. E. M., Azzollini, J., Bacot, F., Balmaña, J., Barile, M., Barjhoux, L., Barkardottir, R. B., Bojesen, S. E., Ejlertsen, B., Flyger, H., Gerdes, A-M., Hansen, T. V. O., Lænkholm, A-V., Nielsen, S. F., Nordestgaard, B. G. & ABCTB Investigators, Dec 2017, In: Nature Genetics. 49, 12, p. 1767-1778 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published
  46. Published

    Association analysis identifies 65 new breast cancer risk loci

    Michailidou, K., Lindström, S., Dennis, J., Beesley, J., Hui, S., Kar, S., Lemaçon, A., Soucy, P., Glubb, D., Rostamianfar, A., Bolla, M. K., Wang, Q., Tyrer, J., Dicks, E., Lee, A., Wang, Z., Allen, J., Keeman, R., Eilber, U., French, J. D. & 31 others, Qing Chen, X., Fachal, L., McCue, K., McCart Reed, A. E., Ghoussaini, M., Carroll, J. S., Jiang, X., Finucane, H., Adams, M., Adank, M. A., Ahsan, H., Aittomäki, K., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Aronson, K. J., Arun, B., Auer, P. L., Bacot, F., Barrdahl, M., Baynes, C., Beckmann, M. W., Behrens, S., Benitez, J., Bermisheva, M., Bernstein, L., Bojesen, S. E., Flyger, H., Nielsen, S. F., Nordestgaard, B. G. & NBCS Collaborators, 2 Nov 2017, In: Nature. 551, 7678, p. 92-94 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

    Zhao, W., Rasheed, A., Tikkanen, E., Lee, J-J., Butterworth, A. S., Howson, J. M. M., Assimes, T. L., Chowdhury, R., Orho-Melander, M., Damrauer, S., Small, A., Asma, S., Imamura, M., Yamauch, T., Chambers, J. C., Chen, P., Sapkota, B. R., Shah, N., Jabeen, S., Surendran, P. & 31 others, Lu, Y., Zhang, W., Imran, A., Abbas, S., Majeed, F., Trindade, K., Qamar, N., Mallick, N. H., Yaqoob, Z., Saghir, T., Rizvi, S. N. H., Memon, A., Rasheed, S. Z., Memon, F-U-R., Mehmood, K., Ahmed, N., Qureshi, I. H., Tanveer-Us-Salam, Iqbal, W., Malik, U., Mehra, N., Kuo, J. Z., Sheu, W. H-H., Guo, X., Nielsen, S. F., Nordestgaard, B. G., Tybjaerg-Hansen, A., Benn, M., Frikke-Schmidt, R., Kamstrup, P. R. & CHD Exome+ Consortium, Oct 2017, In: Nature Genetics. 49, 10, p. 1450-1457 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms

    Howson, J. M. M., Zhao, W., Barnes, D. R., Ho, W-K., Young, R., Paul, D. S., Waite, L. L., Freitag, D. F., Fauman, E. B., Salfati, E. L., Sun, B. B., Eicher, J. D., Johnson, A. D., Sheu, W. H. H., Nielsen, S. F., Lin, W-Y., Surendran, P., Malarstig, A., Wilk, J. B., Tybjærg-Hansen, A. & 31 others, Rasmussen, K. L., Kamstrup, P. R., Deloukas, P., Erdmann, J., Kathiresan, S., Samani, N. J., Schunkert, H., Watkins, H., Do, R., Rader, D. J., Johnson, J. A., Hazen, S. L., Quyyumi, A. A., Spertus, J. A., Pepine, C. J., Franceschini, N., Justice, A., Reiner, A. P., Buyske, S., Hindorff, L. A., Carty, C. L., North, K. E., Kooperberg, C., Boerwinkle, E., Young, K., Graff, M., Peters, U., Absher, D., Hsiung, C. A., Nordestgaard, B. G. & CARDIoGRAMplusC4D, Jul 2017, In: Nature Genetics. 49, 7, p. 1113-1119 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity

    Hendricks, A. E., Bochukova, E. G., Marenne, G., Keogh, J. M., Atanassova, N., Bounds, R., Wheeler, E., Mistry, V., Henning, E., Körner, A., Muddyman, D., McCarthy, S., Hinney, A., Hebebrand, J., Scott, R. A., Langenberg, C., Wareham, N. J., Surendran, P., Howson, J. M., Butterworth, A. S. & 16 others, Danesh, J., Nordestgaard, B. G., Nielsen, S. F., Afzal, S., Papadia, S., Ashford, S., Garg, S., Millhauser, G. L., Palomino, R. I., Kwasniewska, A., Tachmazidou, I., O'Rahilly, S., Zeggini, E., Barroso, I., Farooqi, I. S. & Understanding Society Scientific Group, 29 Jun 2017, In: Scientific Reports. 7, 1, p. 4394

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline

    John, C., Soler Artigas, M., Hui, J., Nielsen, S. F., Rafaels, N., Paré, P. D., Hansel, N. N., Shrine, N., Kilty, I., Malarstig, A., Jelinsky, S. A., Vedel-Krogh, S., Barnes, K., Hall, I. P., Beilby, J., Musk, A. W., Nordestgaard, B. G., James, A., Wain, L. V. & Tobin, M. D., May 2017, In: Thorax. 72, 5, p. 400-408 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published
  52. Published

    Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles

    Gregson, J. M., Freitag, D. F., Surendran, P., Stitziel, N. O., Chowdhury, R., Burgess, S., Kaptoge, S., Gao, P., Staley, J. R., Willeit, P., Nielsen, S. F., Caslake, M., Trompet, S., Polfus, L. M., Kuulasmaa, K., Kontto, J., Perola, M., Blankenberg, S., Veronesi, G., Gianfagna, F. & 31 others, Männistö, S., Kimura, A., Lin, H., Reilly, D. F., Gorski, M., Mijatovic, V., Munroe, P. B., Ehret, G. B., Thompson, A., Uria-Nickelsen, M., Malarstig, A., Dehghan, A., Vogt, T. F., Sasaoka, T., Takeuchi, F., Kato, N., Yamada, Y., Kee, F., Müller-Nurasyid, M., Ferrières, J., Arveiler, D., Amouyel, P., Salomaa, V., Boerwinkle, E., Thompson, S. G., Ford, I., Wouter Jukema, J., Sattar, N., Packard, C. J., Nordestgaard, B. G. & CKDGen consortium, Mar 2017, In: European journal of preventive cardiology. 24, 5, p. 492-504

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Rare and low-frequency coding variants alter human adult height

    Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T. & 31 others, Locke, A. E., Masca, N. G. D., Ng, M. C. Y., Mudgal, P., Rivas, M. A., Vedantam, S., Mahajan, A., Guo, X., Abecasis, G. R., Aben, K. K., Adair, L. S., Alam, D. S., Albrecht, E., Allin, K. H., Bang, L. E., Benn, M., Bork-Jensen, J., Frikke-Schmidt, R., Jensen, G. B., Jørgensen, M. E., Jørgensen, T., Kamstrup, P. R., Linneberg, A., Nielsen, S. F., Nordestgaard, B. G., Thuesen, B. H., Tybjaerg-Hansen, A., Varbo, A., Vestergaard, H., Pers, T. H. & EPIC-InterAct Consortium, 9 Feb 2017, In: Nature. 542, 7640, p. 186-190 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    The OncoArray Consortium: a Network for Understanding the Genetic Architecture of Common Cancers

    Amos, C. I., Dennis, J., Wang, Z., Byun, J., Schumacher, F. R., Gayther, S. A., Casey, G., Hunter, D. J., Sellers, T. A., Gruber, S. B., Dunning, A. M., Michailidou, K., Fachal, L., Doheny, K., Spurdle, A. B., Li, Y., Xiao, X., Romm, J., Pugh, E., Coetzee, G. A. & 73 others, Hazelett, D. J., Bojesen, S. E., Caga-Anan, C., Haiman, C. A., Kamal, A., Luccarini, C., Tessier, D., Vincent, D., Bacot, F., Van Den Berg, D. J., Nelson, S., Demetriades, S., Goldgar, D. E., Couch, F. J., Forman, J. L., Giles, G. G., Conti, D. V., Bickeböller, H., Risch, A., Waldenberger, M., Brüske-Hohlfeld, I., Hicks, B. D., Ling, H., McGuffog, L., Lee, A., Kuchenbaecker, K., Soucy, P., Manz, J., Cunningham, J. M., Butterbach, K., Kote-Jarai, Z., Kraft, P., FitzGerald, L., Lindstrom, S., Adams, M., McKay, J. D., Phelan, C. M., Benlloch, S., Kelemen, L. E., Brennan, P., Riggan, M., O'Mara, T. A., Shen, H., Shi, Y-Y., Thompson, D. J., Goodman, M. T., Nielsen, S. F., Berchuck, A., Laboissiere, S., Schmit, S. L., Shelford, T., Edlund, C. K., Taylor, J. A., Field, J. K., Park, S. K., Offit, K., Thomassen, M., Schmutzler, R., Ottini, L., Hung, R. J., Marchini, J., Amin Al Olama, A., Peters, U., Eeles, R. A., Seldin, M. F., Gillanders, E., Seminara, D., Antoniou, A. C., Pharoah, P. D. P., Chenevix-Trench, G., Chanock, S. J., Simard, J. & Easton, D. F., Jan 2017, In: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 26, 1, p. 126-135

    Research output: Contribution to journalJournal articlepeer-review

  55. Published

    Exome-wide association study of plasma lipids in >300,000 individuals

    Charge Diabetes Working Group, The EPIC-InterAct Consortium, EPIC-CVD Consortium, GOLD Consortium & VA Million Veteran Program, 2017, In: Nature Genetics. 49, 12, p. 1758-1766

    Research output: Contribution to journalJournal articlepeer-review

  56. 2016
  57. Published

    PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

    Southey, M. C., Goldgar, D. E., Winqvist, R., Pylkäs, K., Couch, F., Tischkowitz, M., Foulkes, W. D., Dennis, J., Michailidou, K., van Rensburg, E. J., Heikkinen, T., Nevanlinna, H., Hopper, J. L., Dörk, T., Claes, K. B., Reis-Filho, J., Teo, Z. L., Radice, P., Catucci, I., Peterlongo, P. & 31 others, Tsimiklis, H., Odefrey, F. A., Dowty, J. G., Schmidt, M. K., Broeks, A., Hogervorst, F. B., Verhoef, S., Carpenter, J., Clarke, C., Scott, R. J., Fasching, P. A., Haeberle, L., Ekici, A. B., Beckmann, M. W., Peto, J., Dos-Santos-Silva, I., Fletcher, O., Johnson, N., Bolla, M. K., Bojesen, S., Nielsen, S. F., Flyger, H., Nordestgaard, B. G., Weischer, M., Kjaer, S. K., Høgdall, E. V. S., Høgdall, C. K., Lundvall, L., Nedergaard, L., Engelholm, S. A. & Australian Ovarian Cancer Study Group, Dec 2016, In: Journal of Medical Genetics. 53, 12, p. 800-811 12 p.

    Research output: Contribution to journalJournal articlepeer-review

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ID: 37659