Research output per year
Research output per year
Personal profile
Expertises
I have a comprehensive knowledge about the theoretical and practical aspects of ovarian tissue cryopreservation, and have performed the procedure since 2009 at LRB. I have specialized in human reproductive biology including ovarian pathology and fertility preservation, and my work focuses on human follicle development and the regulatory mechanisms underlying early folliculogenesis.
Í'm is also course-coordinator of The Copenhagen Workshop on Cryopreservation of Ovarian Tissue and chair of ReproYoung (association of young researcher in ReproUnion).
"Main research areas
Reproductive biology; fertility preservation; ovarian tissue cryopreservation; ovarian physiology; endocrinolgy; folliculogenesis; 3D culture systems for isolated preantral follicles; the transforming growth factor beta signaling pathway.
Current research
Evaluating the effect of androgens on human preantral follicle growth, and the importance of the TGF-beta signaling pathway in ovaries from women with PCOS.
Improving the revascularization and grafting of thawed human ovarian tissue using various antioxidants.
Creating an artificial ovary by decellularizing ovarian tissue and regrafting with ovarian cells.
Characterising expression profiles in human follicles.
Culturing isolated preantral follicles in a 3D alginate hydrogel.
Developing new methods for quantifying follicular survival after freezing.
Testing different cryoprotectants and media-supplements for transport and freezing of ovarian tissue.
"Potential conflicts of interest
none
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Collaborations and top research areas from the last five years
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Cryopreservation of ovarian tissue as fertility preservation in young women with multiple sclerosis before stem cell transplantation
Colmorn, L. B., Kristensen, S. G., Larsen, E. C. & Macklon, K. T., 11 Apr 2023, (E-pub ahead of print) In: Multiple Sclerosis and Related Disorders. 74, p. 104716 104716.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of needle puncturing on re-vascularization and follicle survival in xenotransplanted human ovarian tissue
Olesen, H. Ø., Pors, S. E., Adrados, C. S., Zeuthen, M. C., Mamsen, L. S., Pedersen, A. T. & Kristensen, S. G., Dec 2023, In: Reproductive Biology and Endocrinology. 21, 1, 28.Research output: Contribution to journal › Journal article › Research › peer-review
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Human platelet lysate improves the growth and survival of cultured human pre-antral follicles
Subiran Adrados, C., Cadenas, J., Zheng, M., Lund, S., Larsen, E. C., Tanvig, M. H., Greve, V. H., Blanche, P., Andersen, C. Y. & Kristensen, S. G., 26 Jun 2023, (E-pub ahead of print) In: Reproductive BioMedicine Online. 47, 5, p. 103256Research output: Contribution to journal › Journal article › Research › peer-review
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Midkine characterization in human ovaries: potential new variants in follicles
Cadenas, J., Pors, S. E., Hansen, C. P., Olufsen, S. M., Subiran, C., Bøtkjær, J. A., La Cour Poulsen, L., Fedder, J., Dueholm, M., Colmorn, L. B., Kristensen, S. G., Mamsen, L. S. & Andersen, C. Y., 20 Sep 2023, (E-pub ahead of print) In: F&S science.Research output: Contribution to journal › Journal article › Research › peer-review
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Concentrations of oocyte secreted GDF9 and BMP15 decrease with MII transition during human IVM
Cadenas, J., Pors, S. E., Kumar, A., Kalra, B., Kristensen, S. G., Andersen, C. Y. & Mamsen, L. S., 19 Aug 2022, In: Reproductive Biology and Endocrinology. 20, 1, p. 1-10 10 p., 126.Research output: Contribution to journal › Journal article › Research › peer-review