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The Capital Region of Denmark - a part of Copenhagen University Hospital

Sophine Boysen Krintel

(Former)

  1. 2020
  2. Published

    Influence of low socioeconomic status on mortality in granulomatosis with polyangiitis

    Krintel, S. B., Baslund, B., Obel, N. & Faurschou, M., May 2020, In: Scandinavian Journal of Rheumatology. 49, 3, p. 221-224 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2019
  4. Published

    Predictive value of a multi-biomarker disease activity score for clinical remission and radiographic progression in patients with early rheumatoid arthritis: a post-hoc study of the OPERA trial.

    Brahe, C. C. H., Østergaard, M., Johansen, J. S., Defranoux, N., Wang, X., Bolce, R., Sasso, E. H., Ørnbjerg, L. M., Hørslev-Petersen, K., Stengaard-Petersen, K., Junker, P., Ellingsen, T., Ahlquist, P., Lindegaard, H., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Ammitzbøll, C., Jørgensen, A., Krintel, S. B., Raun, J. & Hetland, M. L., 2019, In: Scandinavian Journal of Rheumatology. 48, 1, p. 9-16 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published
  6. 2018
  7. Published

    Plasma MicroRNA Profiles in Patients with Early Rheumatoid Arthritis Responding to Adalimumab plus Methotrexate vs Methotrexate Alone: A Placebo-controlled Clinical Trial

    Sode, J., Krintel, S. B., Carlsen, A. L., Hetland, M. L., Johansen, J. S., Hørslev-Petersen, K., Stengaard-Pedersen, K., Ellingsen, T., Burton, M., Junker, P., Østergaard, M. & Heegaard, N. H. H., Jan 2018, In: Journal of Rheumatology. 45, 1, p. 53-61 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2017
  9. Published
  10. Published

    Hand bone loss in early rheumatoid arthritis during a methotrexate-based treat-to-target strategy with or without adalimumab-a substudy of the optimized treatment algorithm in early RA (OPERA) trial

    Ørnbjerg, L. M., Østergaard, M., Jensen, T., Hørslev-Petersen, K., Stengaard-Pedersen, K., Junker, P., Ellingsen, T., Ahlquist, P., Lindegaard, H., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Ammitzbøll, C. G., Jørgensen, A., Krintel, S. B., Raun, J., Hetland, M. L., Slot, O., Nielsen, L. K., Skjødt, H., Majgaard, O., Lorenzen, T., Horn, H. C., Kowalski, M., Johansen, I. L., Pedersen, P. M., Manilo, N. & Bliddal, H., 1 Apr 2017, In: Clinical Rheumatology. 36, 4, p. 781-789

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2016
  12. Published

    Changes in Multi-Biomarker Disease Activity (MBDA) Score Correlate with Changes in Established Disease Activity Measurements in Patients with Early Ra from The Opera Study

    Brahe, C. C. H., Østergaard, M., Johansen, J. S., Defranoux, N., Hwang, C-C., Bolce, R., Sasso, E., Hørslev-Petersen, K., Steengaard-Pedersen, K., Junker, P., Ellingsen, T., Ahlquist, P., Lindegaard, H., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Ammitzbøll, C., Jørgensen, A., Krintel, S. B., Raun, J. & Hetland, M. L., 2016, In: Annals of the Rheumatic Diseases. 75, Suppl. 2, p. 450 1 p., FRI0067.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  13. Published

    Clinical and radiographic outcome of a treat-to-target strategy using methotrexate and intra-articular glucocorticoids with or without adalimumab induction: a 2-year investigator-initiated, double-blinded, randomised, controlled trial (OPERA)

    Hørslev-Petersen, K., Hetland, M. L., Ørnbjerg, L. M., Junker, P., Pødenphanth, J., Ellingsen, T., Ahlquist, P., Lindegaard, H., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Ammitzbøll, C. G., Jørgensen, A., Krintel, S. B., Raun, J., Johansen, J. S., Østergaard, M., Stengaard-Pedersen, K., OPERA Study-Group, Slot, O., Skjødt, H., Manilo, N. & Bliddal, H., 2016, In: Annals of the Rheumatic Diseases. 75, 9, p. 1645-53 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Hand Bone Loss in Early Rheumatoid Arthritis Is Independent of Adalimumab Treatment. A Substudy of The Optimized Treatment Algorithm in Early RA (Opera) Trial

    Ørnbjerg, L. M., Østergaard, M., Jensen, T., Hørslev-Petersen, K., Stengaard-Pedersen, K., Junker, P., Ellingsen, T., Ahlquist, P., Lindegaard, H., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Ammitzbøll, C. G., Jørgensen, A., Krintel, S. B., Raun, J. & Hetland, M. L., 2016, In: Annals of the Rheumatic Diseases. 75, Suppl. 2, p. 633 1 p., FRI0535.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  15. Published

    Hand Bone Loss in Early Rheumatoid Arthritis Is Independent of Adalimumab Treatment – Results from a Randomized Controlled Clinical Trial

    Ørnbjerg, L. M., Østergaard, M., Jensen, T. D., Hørslev-Petersen, K., Stengaard-Pedersen, K., Junker, P., Ellingsen, T., Ahlquist, P., Lindegaard, H., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Ammitzbøll, C. G., Jørgensen, A., Krintel, S. B., Ravn, J. L. & Hetland, M. L., 2016, In: Arthritis & Rheumatology. 68, S10, 1268.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  16. Published

    Multi-Biomarker Disease Activity (MBDA) Score and Prediction of Radiographic Progression in a Randomized Study of Patients with Early RA Treated with m methotrexate Alone or with Adalimumab

    Brahe, C. C. H., Østergaard, M., Johansen, J. S., Defranoux, N. A., Hwang, C. C., Wang, X., Bolce, R. J., Sasso, E. H., Hørslev-Petersen, K., Stengaard-Pedersen, K., Ørnbjerg, L. M., Junker, P., Ellingsen, T., Ahlquist, P., Lindegaard, H., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I. T., Lottenburger, T., Ammitzbøll, C. G., Jørgensen, A., Krintel, S. B., Raun, J. L. & Hetland, M. L., 2016, In: Arthritis & Rheumatology. 68, S10, 2520.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  17. Published

    Prediction of treatment response to adalimumab: a double-blind placebo-controlled study of circulating microRNA in patients with early rheumatoid arthritis

    Krintel, S. B., Dehlendorff, C., Hetland, M. L., Hørslev-Petersen, K., Andersen, K. K., Junker, P., Pødenphanth, J., Ellingsen, T., Ahlquist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Horn, H. C., Jørgensen, A., Raun, J., Ammitzbøll, C. G., Østergaard, M., Stengaard-Pedersen, K. & Johansen, J. S., 2016, In: The pharmacogenomics journal. 16, 2, p. 141-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2015
  19. Published

    A treat-to-target strategy with methotrexate and intra-articular triamcinolone with or without adalimumab effectively reduces MRI synovitis, osteitis and tenosynovitis and halts structural damage progression in early rheumatoid arthritis: results from the OPERA randomised controlled trial

    Axelsen, M. B., Eshed, I., Hørslev-Petersen, K., Stengaard-Pedersen, K., Hetland, M. L., Møller, J., Junker, M. P., Pødenphanth, J., Schlemmer, A., Ellingsen, T. J., Ahlquist, P., Lindegaard, H., Linauskas, A., Dam, M. Y., Hansen, I. T., Horn, H. C., Ammitzbøll, C. G., Jørgensen, A. J., Krintel, S. B., Raun, J., Krogh, N. S., Johansen, J. S., Ostergaard, M. & OPERA study group, 2015, In: Annals of the Rheumatic Diseases. 74, 5, p. 867-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Circulating Micro-RNA Profiles in Responders to Adalimumab Plus Methotrexate Versus Methotrexate Alone: A Placebo-Controlled Clinical Trial

    OPERA study group, 2015, In: Arthritis & Rheumatology. 67, S10, p. 3832-5 4 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  21. 2014
  22. Published

    Adalimumab added to a treat-to-target strategy with methotrexate and intra-articular triamcinolone in early rheumatoid arthritis increased remission rates, function and quality of life. The OPERA Study: an investigator-initiated, randomised, double-blind, parallel-group, placebo-controlled trial

    Hørslev-Petersen, K., Hetland, M. L., Junker, M. P., Pødenphanth, J., Ellingsen, T. J., Ahlquist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I. T., Horn, H. C., Ammitzbøll, C. G., Jørgensen, A., Krintel, S. B., Raun, J., Johansen, J. S., Østergaard, M., Stengaard-Pedersen, K., OPERA study-group & Slot, O., 2014, In: Annals of the Rheumatic Diseases. 73, 4, p. 654-661

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Genome-wide association analysis of pain reduction in rheumatoid arthritis patients treated with TNF inhibitors.

    Coenen, M. J. H., Umicevic-Mirkov, M., Krintel, S. B., Johansen, J., Miceli-Richard, C., Kallberg, H., Scheffer, H., Kievit, W., van de Laar, M. A., van Riel, P. L. C. M., Mariette, X., Saevarsdottir, A., Hetland, M. L., Vermeulen, S. & Albers, C. A., 2014, In: Arthritis & Rheumatology. 66, S10, p. S1296 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  24. Published

    Genome-wide association analysis of pain reduction in rheumatoid arthritis patients treated with TNF inhibitors.

    Coenen, M., Mirkov, M. U., Krintel, S. B., Johansen, J. S., Miceli-Richard, C., Källberg, H., Padyukov, L., Scheffer, H., Kievit, W., van de Laar, M. A., van Riel, P. L., Mariette, X., Saevarsdottir, S., Hetland, M. L., Vermeulen, S. H. & Albers, C. A., 2014, In: Annals of the Rheumatic Diseases. 73, Suppl. 2, p. 348 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  25. 2013
  26. Published

    The frequency of anti-infliximab antibodies in patients with rheumatoid arthritis treated in routine care and the associations with adverse drug reactions and treatment failure

    Krintel, S. B., Grunert, V. P., Hetland, M. L., Johansen, J. S., Rothfuss, M., Palermo, G., Essioux, L. & Klause, U., Jul 2013, In: Rheumatology (Oxford, England). 52, 7, p. 1245-53 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    A treat-to-target strategy with methotrexate and intra-articular triamcinolone with or without added adalimumab reduces synovitis, osteitis and tenosynovitis and halts structural damage progression in early rheumatoid arthritis: The OPERA magnetic resonance imaging sub-study

    Axelsen, M. B., Eshed, I., Hørslev-Petersen, K., Steengaard-Pedersen, K., Hetland, M. L., Møller, J. M., Junker, P., Pødenphanth, J., Ellingsen, T., Ahlqvist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Horn, H. C., Ammitzbøll, C. G., Jørgensen, A., Krintel, S. B., Raun, J., Johansen, J. S., Krogh, N. S. & Østergaard, M., 2013, In: Arthritis & Rheumatism. 65, Suppl. 10, p. S1199 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  28. Published

    Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans

    Cobb, J. E., Plant, D., Flynn, E., Tadjeddine, M., Dieudé, P., Cornélis, F., Ärlestig, L., Dahlqvist, S. R., Goulielmos, G., Boumpas, D. T., Sidiropoulos, P., Krintel, S. B., Ørnbjerg, L. M., Hetland, M. L., Klareskog, L., Haeupl, T., Filer, A., Buckley, C. D., Raza, K., Witte, T., Schmidt, R. E., FitzGerald, O., Veale, D., Eyre, S. & Worthington, J., 2013

    Research output: Other contributionNet publication - Internet publicationResearchpeer-review

  29. Published

    Improved remission rates acquired by adding adalimumab to methotrexate and intraarticular glucocorticoid cannot be maintained after withdrawal of adalimumab. A 2-year investigator initiated randomized, controlled study on early rheumatoid arthritis.

    Hørslev-Petersen, K., Hetland, M. L., Junker, P., Pødenphanth, J., Ellingsen, T., Ahlqvist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Jørgensen, A., Krintel, S. B., Raun, J., Ammitzbøll, C. G., Johansen, J. S., Østergaard, M. & Steengaard-Pedersen, K., 2013, In: Annals of the Rheumatic Diseases. 72, Suppl. 3, p. 236 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  30. Published

    Induction therapy with adalimumab on top of an aggressive treat-to-target strategy with methotrexate and intraarticular corticosteroid reduces radiographic erosive progression in early rheumatoid arthritis, even after withdrawal of adalimumab. Results of a 2-year trial (OPERA)

    Hørslev-Petersen, K., Ørnbjerg, L. M., Hetland, M. L., Junker, P., Pødenphanth, J., Ellingsen, T., Ahlqvist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Jørgensen, A., Krintel, S. B., Raun, J., Ammitzbøll, C. G., Johansen, J. S., Østergaard, M. & Steengaard-Pedersen, K., 2013, In: Arthritis & Rheumatism. 65, Suppl. 10, p. S600-1 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  31. Published

    Micro-RNA expression profiles as biomarkers for prediction of treatment response to adalimumab in patients with early rheumatoid arthritis.

    Krintel, S. B., Dehlendorff, C., Hetland, M. L., Hørslev-Petersen, K., Andersen, K. K., Junker, P., Pødenphanth, J., Ellingsen, T., Ahlqvist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Horn, H. C., Jørgensen, A., Raun, J., Ammitzbøll, C. G., Østergaard, M., Stengaard-Pedersen, K. & Johansen, J. S., 2013, In: Annals of the Rheumatic Diseases. 72, Suppl. 3, p. 584 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  32. Published

    MicroRNA expression profiles associated with response to adalimumab and methotrexate versus methotrexate: A placebo-controlled clinical trial

    Krintel, S. B., Dehlendorff, C., Hetland, M. L., Hørslev-Petersen, K., Andersen, K. K., Junker, P., Pødenphanth, J., Ellingsen, T., Ahlqvist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Horn, H. C., Jørgensen, A., Raun, J., Ammitzbøll, C. G., Østergaard, M., Steengaard-Pedersen, K. & Johansen, J. S., 2013, In: Arthritis & Rheumatism. 65, Suppl. 10, p. S374-5 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  33. Published
  34. Published

    Very high remission rates are achieved by methotrexate and intraarticular glucocorticoids independent of induction therapy with adalimumab: Year 2 clinical results of an investigator-initiated randomised, controlled clinical trial of early, rheumatoid arthritis

    Hørslev-Petersen, K., Hetland, M. L., Junker, P., Pødenphanth, J., Ellingsen, T., Ahlqvist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Jørgensen, A., Krintel, S. B., Raun, J., Ammitzbøll, C. G., Johansen, J. S. & Østergaard, M., 2013, In: Arthritis & Rheumatism. 65, Suppl. 10, p. S1148 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  35. 2012
  36. Published

    CD6 and syntaxin binding protein 6 variants and response to tumor necrosis factor alpha inhibitors in Danish patients with rheumatoid arthritis

    Krintel, S. B., Essioux, L., Wool, A., Johansen, J. S., Schreiber, E., Zekharya, T., Akiva, P., Østergaard, M. & Hetland, M. L., 2012

    Research output: Other contributionNet publication - Internet publicationResearchpeer-review

  37. Published

    Genome wide association analysis of pain reduction in rheumatoid arthritis patients treated with anti-TNF medication. Results of the DREAM and DANBIO registries.

    Coehnen, M. J. H., Mirkov, M. U., Scheffer, H., Krintel, S. B., Vermeulen, S. H., Johansen, J. S., Kiewit, W., Van de Laar, M. A. F. J., Van Riel, P. L. C. M., Franke, B. & Hetland, M. L., 2012, In: Arthritis & Rheumatism. 64, 10 suppl., p. S188 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  38. Published

    Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis

    Krintel, S. B., Palermo, G., Johansen, J. S., Germer, S., Essioux, L., Benayed, R., Badi, L., Østergaard, M. & Hetland, M. L., 2012, In: Pharmacogenetics and Genomics. 22, 8, p. 577-89 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Remission rates increase substantially by adding adalimumab to methotrexate and intra-articular clucocorticoid in patients with early rheumatoid arthritis – 1-year results of investigator-initiated, double-blinded randomized clinical trial (OPERA).

    Hørslev-Petersen, K., Hetland, M. L., Junker, P., Pødenphanth, J., Ellingsen, T., Ahlquist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Horn, H. C., Jørgensen, A., Krintel, S. B., Raun, J., Ammitzbøll, C. G., Johansen, J. S., Østergaard, M. & Stengaard-Pedersen, K., 2012, In: Scandinavian Journal of Rheumatology. Supplement. 41, 126 suppl., p. 17-8 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  40. Published

    Remisson rates increase substantially by adding adalimumab to methotrexate and intra-articular glucocorticoid in patients with early rheumatoid arthritis – 1-year results of investigator-initiated, double-blinded randomized clinical trial (OPERA).

    Hørslev-Petersen, K., Hetland, M. L., Junker, P., Pødenphanth, J., Ellingsen, T., Ahlquist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Horn, H. C., Jørgensen, A., Krintel, S. B., Raun, J., Ammizbøll, C. G., Johansen, J. S., Østergaard, M. & Steengaard-Pedersen, K., 2012, In: Annals of the Rheumatic Diseases. 71, 3 suppl., p. 360-1 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  41. 2011
  42. Published

    Adalimumab added to Methotrexate and intra-articular glucocorticoid increases remission rates at one year in early, DMARD-naïve patients with rheumatoid arthritis - An investigator-initiated randomized, controlled, double-blinded study.

    Hørslev-Petersen, K., Hetland, M. L., Junker, P., Pødenphanth, J., Ellingsen, T., Ahlqvist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Horn, H. C., Jørgensen, A., Krintel, S. B., Raun, J., Ammizbøll, C. G., Johansen, J. S., Østergaard, M. & Stengaard-Pedersen, K., 2011, In: Arthritis & Rheumatism. 63, 10 (suppl.), p. S147 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  43. Published

    Genetic variations within the CD6 and syntaxin binding protein 6 genes associated with response to tumor necrosis factor alpha inhibitors in Danish patients with rheumatoid arthritis treated in routine care.

    Krintel, S. B., Palermo, G., Wool, A., Johansen, J. S., Essioux, L., Schreiber, E., Zekharya, T., Akiva, P., Østergaard, M. & Hetland, M. L., 2011, In: Arthritis & Rheumatism. 63, 10 (Suppl.), p. S149 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  44. Published

    Promoter polymorphisms in the chitinase 3-like 1 gene influence the serum concentration of YKL-40 in Danish patients with rheumatoid arthritis and in healthy subjects

    Nielsen, K. R., Steffensen, R. N., Boegsted, M., Baech, J., Lundbye-Christensen, S., Hetland, M. L., Krintel, S. B., Johnsen, H. E., Nyegaard, M. & Johansen, J. S., 2011, In: Arthritis Research & Therapy. 13, 3, p. R109 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2010
  46. Published

    Identification of polymorphism associated with treatment response to anti-TNF in Danish RA patients by genome-wide association scan.

    Krintel, S. B., Palermo, G., Johansen, J. S., Germer, S., Essioux, L., Benayed, R. & Hetland, M. L., 2010, In: Annals of the Rheumatic Diseases. 69, 3, p. 207 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

ID: 36882