Research output per year
Research output per year
Personal profile
Research areas
Bioinformatician, Single-cell data analysis, Computational immunology, Genome-scale metabolic modeling.
Main research areas
Shawez Khan obtained his first Master (Bioinformatics) in 2010 from India and his second Master (Systems and Synthetic Biology) in 2016 from France. He received his Ph.D. in Bioinformatics from KU Leuven, Belgium in 2019. During his Ph.D., he mainly worked on the re-use of publicly available transcriptomics data and genome-scale metabolic modeling of endothelial cells to identify novel anti-angiogenic metabolic targets. Shawez is interested in gene expression analysis, constraint-based modeling and Public data mining.
Current research
Throughout his Ph.D., Shawez handled a variety of multi-omics datasets of cancer patients and specialized in applications of transcriptomic analysis related to anti-angiogenic metabolic targets. Afterward, his first career at CCIT, Herlev Hospital, Denmark, enabled him to build skills in analyzing and interpreting the single-cell multi-omics data (in-house and public) generated from cancer patients of diverse solid tumors to access the functional heterogeneity of tumor-infiltrating lymphocytes (TILs).
Potential conflicts of interest
None
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Research output
- 6 Journal article
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Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer
Johansen, A. Z., Carretta, M., Thorseth, M-L., Khan, S., Fjæstad, K. Y., Brøchner, C. B., Linder, H., Ankjærgaard, C., Donia, M., Chen, I., Nielsen, D. L., Behrens, C. P. & Madsen, D. H., 12 May 2022, In: Pharmaceutics. 14, 5, 1046.Research output: Contribution to journal › Journal article › Research › peer-review
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Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast
Geldhof, V., de Rooij, L. P. M. H., Sokol, L., Amersfoort, J., De Schepper, M., Rohlenova, K., Hoste, G., Vanderstichele, A., Delsupehe, A-M., Isnaldi, E., Dai, N., Taverna, F., Khan, S., Truong, A-C. K., Teuwen, L-A., Richard, F., Treps, L., Smeets, A., Nevelsteen, I., Weynand, B., & 14 others, 20 Sep 2022, In: Nature Communications. 13, 1, p. 5511 5511.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo
De Oliveira, T., Goldhardt, T., Edelmann, M., Rogge, T., Rauch, K., Kyuchukov, N. D., Menck, K., Bleckmann, A., Kalucka, J., Khan, S., Gaedcke, J., Haubrock, M., Beissbarth, T., Bohnenberger, H., Planque, M., Fendt, S-M., Ackermann, L., Ghadimi, M. & Conradi, L-C., 28 Feb 2021, In: Cancers. 13, 5, p. 1-24 24 p., 1011.Research output: Contribution to journal › Journal article › Research › peer-review
16 Citations (Scopus) -
Loss of Ambra1 promotes melanoma growth and invasion
Di Leo, L., Bodemeyer, V., Bosisio, F. M., Claps, G., Carretta, M., Rizza, S., Faienza, F., Frias, A., Khan, S., Bordi, M., Pacheco, M. P., Di Martino, J., Bravo-Cordero, J. J., Daniel, C. J., Sears, R. C., Donia, M., Madsen, D. H., Guldberg, P., Filomeni, G., Sauter, T., & 3 others, 5 May 2021, In: Nature Communications. 12, 1, p. 2550 2550.Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid Identification of the Tumor-Specific Reactive TIL Repertoire via Combined Detection of CD137, TNF, and IFNγ, Following Recognition of Autologous Tumor-Antigens
Draghi, A., Chamberlain, C. A., Khan, S., Papp, K., Lauss, M., Soraggi, S., Radic, H. D., Presti, M., Harbst, K., Gokuldass, A., Kverneland, A., Nielsen, M., Westergaard, M. C. W., Andersen, M. H., Csabai, I., Jönsson, G., Szallasi, Z., Svane, I. M. & Donia, M., 11 Oct 2021, In: Frontiers in Immunology. 12, p. 705422 705422.Research output: Contribution to journal › Journal article › Research › peer-review
4 Citations (Scopus)