Research output per year
Research output per year
Personal profile
Expertises
Immunology, Biotechnology, Tumor immunology
Main research areas
The immune system often fails to respond effectively against immunogenic antigens and become tolerant towards these antigens. We need to overcome this acquired state of tolerance for cancer immunotherapy to succeed. Immune regulatory proteins; e.g., programmed death-ligand 1 (PD-L1), PD-L2, indoleamine 2,3-dioxygenase (IDO), IDO2, tryptophan 2,3-dioxygenase (TDO), forkhead box P3 (Foxp3), and FoxO3 play a vital role in the immune suppression and tolerance induction of anti cancer immune responses. The main research area covers characterization and identification of self-reactive T cells that specifically recognized human leukocyte antigen (HLA)-restricted epitopes derived from these immune regulatory proteins.
Current research
My current research is based on identification and characterization of immune response against Programmed Cell Death Ligand 1 and 2 (PD-L1 and PD-L2) epitopes.
Fingerprint
Dive into the research topics where Shamaila Munir Ahmad is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Anti-PD-L1/PD-L2 therapeutic vaccination in untreated chronic lymphocytic leukemia patients with unmutated IgHV
Klausen, U., Grauslund, J. H., Jørgensen, N. G. D., Ahmad, S. M., Jonassen, M., Weis-Banke, S. E., Martinenaite, E., Pedersen, L. B., Lisle, T. L., Gang, A. O., Enggaard, L., Hansen, M., Holmström, M. O., Met, Ö., Svane, I. M., Niemann, C. U., Pedersen, L. M. & Andersen, M. H., 2022, In: Frontiers in Oncology. 12, p. 1-13 13 p., 1023015.Research output: Contribution to journal › Journal article › Research › peer-review
-
Author Correction: A phase 1/2 trial of an immune-modulatory vaccine against IDO/PD-L1 in combination with nivolumab in metastatic melanoma
Kjeldsen, J. W., Lorentzen, C. L., Martinenaite, E., Ellebaek, E., Donia, M., Holmstroem, R. B., Klausen, T. W., Madsen, C. O., Ahmed, S. M., Weis-Banke, S. E., Holmström, M. O., Hendel, H. W., Ehrnrooth, E., Zocca, M-B., Pedersen, A. W., Andersen, M. H. & Svane, I. M., Apr 2022, 1 p.Research output: Other contribution › Research
1 Citation (Scopus) -
Peptide vaccination activating Galectin-3-specific T cells offers a novel means to target Galectin-3-expressing cells in the tumor microenvironment
Bendtsen, S. K., Perez-Penco, M., Hübbe, M. L., Martinenaite, E., Orebo Holmström, M., Weis-Banke, S. E., Grønne Dahlager Jørgensen, N., Jørgensen, M. A., Munir Ahmad, S., Jensen, K. M., Friese, C., Lundsager, M. T., Johansen, A. Z., Carretta, M., Ødum, N., Met, Ö., Svane, I. M., Madsen, D. H. & Andersen, M. H., 27 Jan 2022, In: OncoImmunology. 11, 1, p. 2026020 2026020.Research output: Contribution to journal › Journal article › Research › peer-review
-
An immunogenic first-in-human immune modulatory vaccine with PD-L1 and PD-L2 peptides is feasible and shows early signs of efficacy in follicular lymphoma
Klausen, U., Grønne Dahlager Jørgensen, N., Grauslund, J. H., Munir Ahmad, S., Gang, A. O., Martinenaite, E., Weis-Banke, S. E., Breinholt, M. F., Novotny, G. W., Kjeldsen, J. W., Orebo Holmström, M., Pedersen, L. B., Poulsen, C. B., Hansen, P. B., Met, Ö., Svane, I. M., Niemann, C. U., Pedersen, L. M. & Andersen, M. H., 2021, In: OncoImmunology. 10, 1, 1975889.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
A phase 1/2 trial of an immune-modulatory vaccine against IDO/PD-L1 in combination with nivolumab in metastatic melanoma
Kjeldsen, J. W., Lorentzen, C. L., Martinenaite, E., Ellebaek, E., Donia, M., Holmstroem, R. B., Klausen, T. W., Madsen, C. O., Ahmed, S. M., Weis-Banke, S. E., Holmström, M. O., Hendel, H. W., Ehrnrooth, E., Zocca, M. B., Pedersen, A. W., Andersen, M. H. & Svane, I. M., Dec 2021, In: Nature Medicine. 27, 12, p. 2212-2223 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
47 Citations (Scopus)