Personal profile
Expertises
Molecular biology techniques; tissue and cell culture techniques; sequence analysis
Main research areas
Virology; Molecular biology; Genetics; Antiviral resistance; Hepatology
Current research
Development of cell culture systems for hepatitis C virus.
Study of the molecular determinants and mechanisms of viral resistance against polymerase inhibitors.
Potential conflicts of interest
None
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Collaborations and top research areas from the last five years
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Enzymatic Glucosylation Enhances the Solubility of Niclosamide but Abrogates Its Therapeutic Efficacy
Lax, B. M., Escorial García, M., Fernandez-Antunez, C., Bukh, J., Ramirez, S. & Welner, D. H., 10 Feb 2026, In: ACS omega. 11, 5, p. 8667-8677 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Substitutions M478K and A482G in the polymerase of yellow fever virus confer resistance to sofosbuvir and uprifosbuvir in vitro
Binderup, A., Elorz, I. O., Ryberg, L. A., Fahnøe, U., Mikkelsen, L., Soto, A., Rosas, A. L. R., Delang, L., Bukh, J. & Ramirez, S., 2026, In: Antiviral Research. 249, 106381.Research output: Contribution to journal › Journal article › Research › peer-review
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Intranasal recombinant protein subunit vaccine targeting TLR3 induces respiratory tract IgA and CD8 T cell responses and protects against respiratory virus infection
Wørzner, K., Schmidt, S. T., Zimmermann, J., Tami, A., Polacek, C., Fernandez-Antunez, C., Hartmann, K. T., Jensen, R. F., Hansen, J. S., Illigen, K., Isling, L. K., Erbs, G., Jungersen, G., Rosenkrands, I., Offersgaard, A., Gottwein, J., Holmbeck, K., Jensen, H. E., Ramirez, S. & Follmann, F. & 2 others, , Mar 2025, In: EBioMedicine. 113, 105615.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus) -
SARS-CoV-2 Mpro inhibitor ensitrelvir: asymmetrical cross-resistance with nirmatrelvir and emerging resistance hotspots
Zhou, Y., Gammeltoft, K. A., Tjørnelund-Sjursen, H. D., Ryberg, L. A., Offersgaard, A., Czarnota, A., Duan, Z., Pham, L. V., Fahnøe, U., Peters, G. H. J., Ramirez, S., Bukh, J. & Gottwein, J. M., Dec 2025, In: Emerging microbes & infections. 14, 1, p. 2552716 2552716.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
SARS-CoV-2 Remdesivir Exposure Leads to Different Evolutionary Pathways That Converge in Moderate Levels of Drug Resistance
Fernandez-Antunez, C., Ryberg, L. A., Wang, K., Pham, L. V., Mikkelsen, L. S., Fahnøe, U., Hartmann, K. T., Jensen, H. E., Holmbeck, K., Bukh, J. & Ramirez, S., 29 Jul 2025, In: Viruses. 17, 8, 1055.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus)