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Rúna Louise Mortansdóttir Nolsöe


Research activity per year

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Personal profile

Main research areas

Research areas:

Type 1 diabetes identification of biomarkers that influence the risk of Type 1 diabetes.



Diabetes and gestational diabetes.


Current research:

Type 1 diabetes; genetics, biomarkers, environmental factors.





Characteristics and early outcomes of patients hospitalised for COVID-19 in North Zealand, Denmark. 

Lendorf ME, Boisen MK, Kristensen PL, Løkkegaard ECL, Krog SM, Brandi L, Brinth LS, Nolsöe RLM, Ryrsø C, Eiken P, Bestle MH, Jørgensen IM, Pedersen-Bjergaard U, Lindegaard B, Christensen TB, Fischer TK.

Dan Med J. 2020 Aug 12;67(9):A06200428.

PMID: 32800073


Selenium supplementation for patients with Graves' hyperthyroidism (the GRASS trial): study protocol for a randomized controlled trial. 

Watt T, Cramon P, Bjorner JB, Bonnema SJ, Feldt-Rasmussen U, Gluud C, Gram J, Hansen JL, Hegedüs L, Knudsen N, Bach-Mortensen P, Nolsøe R, Nygaard B, Pociot F, Skoog M, Winkel P, Rasmussen AK.

Trials. 2013 Apr 30;14:119. doi: 10.1186/1745-6215-14-119.

PMID: 23782950 Free PMC article. Clinical Trial.


Functional SOCS1 polymorphisms are associated with variation in obesity in whites. 

Gylvin T, Ek J, Nolsøe R, Albrechtsen A, Andersen G, Bergholdt R, Brorsson C, Bang-Berthelsen CH, Hansen T, Karlsen AE, Billestrup N, Borch-Johnsen K, Jørgensen T, Pedersen O, Mandrup-Poulsen T, Nerup J, Pociot F.

Diabetes Obes Metab. 2009 Mar;11(3):196-203. doi: 10.1111/j.1463-1326.2008.00900.x.

PMID: 19215277


Association of interferon-gamma and interleukin 10 genotypes and serum levels with partial clinical remission in type 1 diabetes. 

Alizadeh BZ, Hanifi-Moghaddam P, Eerligh P, van der Slik AR, Kolb H, Kharagjitsingh AV, Pereira Arias AM, Ronkainen M, Knip M, Bonfanti R, Bonifacio E, Devendra D, Wilkin T, Giphart MJ, Koeleman BP, Nolsøe R, Mandrup Poulsen T, Schloot NC, Roep BO; DIABMARKER Study Group.

Clin Exp Immunol. 2006 Sep;145(3):480-4. doi: 10.1111/j.1365-2249.2006.03172.x.

PMID: 16907917 Free PMC article.


Association of a microsatellite in FASL to type II diabetes and of the FAS-670G>A genotype to insulin resistance. 

Nolsøe RL, Hamid YH, Pociot F, Paulsen S, Andersen KM, Borch-Johnsen K, Drivsholm T, Hansen T, Pedersen O, Mandrup-Poulsen T.

Genes Immun. 2006 Jun;7(4):316-21. doi: 10.1038/sj.gene.6364300. Epub 2006 May 4.

PMID: 16691186


Functional promoter haplotypes of the human FAS gene are associated with the phenotype of SLE characterized by thrombocytopenia. 

Nolsøe RL, Kelly JA, Pociot F, Moser KL, Kristiansen OP, Mandrup-Poulsen T, Harley JB.

Genes Immun. 2005 Dec;6(8):699-706. doi: 10.1038/sj.gene.6364259.

PMID: 16163374


Is puberty an accelerator of type 1 diabetes in IL6-174CC females? 

Gillespie KM, Nolsøe R, Betin VM, Kristiansen OP, Bingley PJ, Mandrup-Poulsen T, Gale EA.

Diabetes. 2005 Apr;54(4):1245-8. doi: 10.2337/diabetes.54.4.1245.

PMID: 15793269


Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes. 

Hamid YH, Rose CS, Urhammer SA, Glümer C, Nolsøe R, Kristiansen OP, Mandrup-Poulsen T, Borch-Johnsen K, Jorgensen T, Hansen T, Pedersen O.

Diabetologia. 2005 Feb;48(2):251-60. doi: 10.1007/s00125-004-1623-0. Epub 2005 Jan 11.

PMID: 15645209


Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity. 

Gylvin T, Nolsøe R, Hansen T, Nielsen EMD, Bergholdt R, Karlsen AE, Billestrup N, Borch-Johnsen K, Pedersen O, Mandrup-Poulsen T, Nerup J, Pociot F.

Diabetologia. 2004 Jul;47(7):1273-1277. doi: 10.1007/s00125-004-1440-5. Epub 2004 Jul 13.

PMID: 15249995


Type 1 database mellitus: an inflammatory disease of the islet. 

Bergholdt R, Heding P, Nielsen K, Nolsøe R, Sparre T, Størling J, Nerup J, Pociot F, Mandrup-Poulsen T.

Adv Exp Med Biol. 2004;552:129-53.

PMID: 15622962 Review. No abstract available.


Mutation scan of a type 1 diabetes candidate gene: the human interleukin-18 binding protein gene. 

Nolsøe RL, Pociot F, Novick D, Rubinstein M, Kim SH, Dinarello CA, Mandrup-Poulsen T.

Ann N Y Acad Sci. 2003 Nov;1005:332-9. doi: 10.1196/annals.1288.053.

PMID: 14679086


Association of a functional 17beta-estradiol sensitive IL6-174G/C promoter polymorphism with early-onset type 1 diabetes in females. 

Kristiansen OP, Nolsøe RL, Larsen L, Gjesing AM, Johannesen J, Larsen ZM, Lykkesfeldt AE, Karlsen AE, Pociot F, Mandrup-Poulsen T; DIEGG; DSGD.

Hum Mol Genet. 2003 May 15;12(10):1101-10. doi: 10.1093/hmg/ddg132.

PMID: 12719374


Complete mutation scan of the human Fas ligand gene: linkage studies in Type I diabetes mellitus families. 

Nolsøe RL, Kristiansen OP, Larsen ZM, Johannesen J, Pociot F, Mandrup-Poulsen T.

Diabetologia. 2002 Jan;45(1):134-9. doi: 10.1007/s125-002-8254-7.

PMID: 11845233


The intercellular adhesion molecule-1 K469E polymorphism in type 1 diabetes. 

Kristiansen OP, Nolsøe RL, Holst H, Reker S, Larsen ZM, Johannesen J, Nerup J, Pociot F, Mandrup-Poulsen T; Danish Study Group of IDDM in Childhood.

Immunogenetics. 2000 Nov;52(1-2):107-11. doi: 10.1007/s002510000258.

PMID: 11132145


Complete molecular scanning of the human Fas gene: mutational analysis and linkage studies in families with type I diabetes mellitus. The Danish Study Group of Diabetes in Childhood and The Danish IDDM Epidemiology and Genetics Group. 

Nolsøe RL, Kristiansen OP, Sangthongpitag K, Larsen ZM, Johannesen J, Karlsen AE, Pociot F, Nerup J, Verge CF, Mandrup-Poulsen T.

Diabetologia. 2000 Jun;43(6):800-8. doi: 10.1007/s001250051378.

PMID: 10907126









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