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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2020
  2. Published

    Biofilms of Mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

    Kolpen, M., Jensen, P. Ø., Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, B. G., Johansen, U. R., Bjarnsholt, T. & Høiby, N., 27 Jan 2020, In : Antimicrobial Agents and Chemotherapy. 64, 2, p. e01212-19 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2019
  4. Published

    Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms

    Crabbé, A., Jensen, P. Ø., Bjarnsholt, T. & Coenye, T., Oct 2019, In : Trends in Microbiology. 27, 10, p. 850-863 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published
  6. Published
  7. Published

    The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model

    Granslo, H. N., Aarag Fredheim, E. G., Esaiassen, E., Christophersen, L., Jensen, P. Ø., Mollnes, T. E., Moser, C., Flaegstad, T., Klingenberg, C. & Cavanagh, J. P., Jun 2019, In : APMIS - Journal of Pathology, Microbiology and Immunology. 127, 6, p. 475-483 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published
  9. Published

    Antibiotic therapy as personalized medicine - general considerations and complicating factors

    Moser, C., Lerche, C. J., Thomsen, K., Hartvig, T., Schierbeck, J., Jensen, P. Ø., Ciofu, O. & Høiby, N., May 2019, In : APMIS - Journal of Pathology, Microbiology and Immunology. 127, 5, p. 361-371 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis

    Lerche, C. J., Christophersen, L. J., Goetze, J. P., Nielsen, P. R., Thomsen, K., Enevold, C., Høiby, N., Jensen, P. Ø., Bundgaard, H. & Moser, C., 2019, In : PLoS One. 14, 4, 16 p., e0215333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air

    Jensen, P. Ø., Møller, S. A., Lerche, C. J., Moser, C. E., Bjarnsholt, T., Ciofu, O., Faurholt-Jepsen, D., Høiby, N. & Mette, K., 2019, In : Biofilm. 1, 2019, p. 1000008

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Oxygen Restriction Generates Difficult-to-Culture P. aeruginosa

    Kvich, L., Fritz, B., Crone, S., Kragh, K. N., Kolpen, M., Sønderholm, M., Andersson, M., Koch, A., Jensen, P. Ø. & Bjarnsholt, T., 2019, In : Frontiers in Microbiology. 10, p. 1992

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published
  14. 2018
  15. Published

    Implants induce a new niche for microbiomes

    Jakobsen, T. H., Eickhardt, S. R., Gheorghe, A. G., Stenqvist, C., Sønderholm, M., Stavnsberg, C., Jensen, P. Ø., Odgaard, A., Whiteley, M., Moser, C., Hvolris, J., Hougen, H. P. & Bjarnsholt, T., Aug 2018, In : APMIS - Journal of Pathology, Microbiology and Immunology. 126, 8, p. 685-692 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published
  17. Published

    Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms

    Gade, P. A. V., Olsen, T. B., Jensen, P. Ø., Kolpen, M., Høiby, N., Henneberg, K-Å. & Sams, T., 2018, In : PLoS One. 13, 6, p. e0198909

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model

    Sønderholm, M., Koren, K., Wangpraseurt, D., Jensen, P. Ø., Kolpen, M., Kragh, K. N., Bjarnsholt, T. & Kühl, M., 2018, In : NPJ biofilms and microbiomes. 4, p. 3-13 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2017
  20. Published

    The Consequences of Being in an Infectious Biofilm: Microenvironmental Conditions Governing Antibiotic Tolerance

    Sønderholm, M., Bjarnsholt, T., Alhede, M., Kolpen, M., Jensen, P. Ø., Kühl, M. & Kragh, K. N., 12 Dec 2017, In : International Journal of Molecular Sciences. 18, 12, p. E2688

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase

    Damgaard, D., Bjørn, M. E., Jensen, P. Ø. & Nielsen, C. H., Dec 2017, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 32, 1, p. 1203-1208 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Hyperbaric Oxygen Sensitizes Anoxic Pseudomonas aeruginosa Biofilm to Ciprofloxacin

    Kolpen, M., Lerche, C. J., Kragh, K. N., Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, T., Ciofu, O., Moser, C., Kühl, M., Høiby, N. & Jensen, P. Ø., Nov 2017, In : Antimicrobial Agents and Chemotherapy. 61, 11, p. e01024-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published
  24. Published
  25. Published
  26. Published

    Pseudomonas aeruginosa Aggregate Formation in an Alginate Bead Model System Exhibits-Like Characteristics

    Sønderholm, M., Kragh, K. N., Koren, K., Jakobsen, T. H., Darch, S. E., Alhede, M., Jensen, P. Ø., Whiteley, M., Kühl, M. & Bjarnsholt, T., 1 May 2017, In : Applied and Environmental Microbiology. 83, 9, p. e00113-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Use of Oxygen Therapies in Wound Healing: Focus on Topical and Hyperbaric Oxygen Treatment

    Gottrup, F., Dissemond, J., Baines, C., Frykberg, R., Jensen, P. Ø., Kot, J., Kröger, K. & Longobardi, P., May 2017, In : Journal of wound care. 26, Sup5, p. S1-S42

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published
  29. Published

    Diagnosis of biofilm infections in cystic fibrosis patients

    Høiby, N., Bjarnsholt, T., Moser, C., Jensen, P. Ø., Kolpen, M., Qvist, T., Aanaes, K., Pressler, T., Skov, M. & Ciofu, O., Apr 2017, In : APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 125, 4, p. 339-343 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  30. Published
  31. 2016
  32. Published
  33. Published

    Development of a rechargeable optical hydrogen peroxide sensor - sensor design and biological application

    Koren, K., Jensen, P. Ø. & Kühl, M., 21 Jul 2016, In : Analyst. 141, 14, p. 4332-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published
  35. Published
  36. Published

    Role of Multicellular Aggregates in Biofilm Formation

    Kragh, K. N., Hutchison, J. B., Melaugh, G., Rodesney, C., Roberts, A. E. L., Irie, Y., Jensen, P. Ø., Diggle, S. P., Allen, R. J., Gordon, V. & Bjarnsholt, T., 22 Mar 2016, In : mBio. 7, 2, p. e00237

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment

    Mette, K., Mousavi, N., Sams, T., Bjarnsholt, T., Ciofu, O., Moser, C., Kühl, M., Høiby, N. & Jensen, P. Ø., Feb 2016, In : International Journal of Antimicrobial Agents. 47, 2, p. 163-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published
  39. Published

    Diffusion Retardation by Binding of Tobramycin in an Alginate Biofilm Model

    Cao, B., Christophersen, L., Mette, K., Jensen, P. Ø., Sneppen, K., Høiby, N., Moser, C. & Sams, T., 2016, In : P L o S One. 11, 4, p. e0153616

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions

    Mette, K., Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, T., Ciofu, O., Høiby, N. & Jensen, P. Ø., 2016, In : Pathogens and Disease. 74, p. ftv086

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2015
  42. Published

    Antibiofilm Properties of Acetic Acid

    Bjarnsholt, T., Alhede, M., Jensen, P. Ø., Nielsen, A. K., Johansen, H. K., Homøe, P., Høiby, N., Givskov, M. & Kirketerp-Møller, K., 1 Jul 2015, In : Advances in Wound Care. 4, 7, p. 363-372 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Antibiotic penetration and bacterial killing in a Pseudomonas aeruginosa biofilm model

    Cao, B., Christophersen, L., Thomsen, K., Sønderholm, M., Bjarnsholt, T., Jensen, P. Ø., Høiby, N. & Moser, C., Jul 2015, In : The Journal of antimicrobial chemotherapy. 70, 7, p. 2057-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils

    Thomsen, K., Christophersen, L., Bjarnsholt, T., Jensen, P. Ø., Moser, C. & Høiby, N., Jul 2015, In : Infection and Immunity. 83, 7, p. 2686-93 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Denitrification by cystic fibrosis pathogens - Stenotrophomonas maltophilia is dormant in sputum

    Mette, K., Kragh, K. N., Bjarnsholt, T., Line, L., Hansen, C. R., Dalbøge, C. S., Hansen, N. J., Kühl, M., Høiby, N. & Jensen, P. Ø., Jan 2015, In : International journal of medical microbiology : IJMM. 305, 1, p. 1-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published
  47. 2014
  48. Published

    Plasmodium falciparum avoids change in erythrocytic surface expression of phagocytosis markers during inhibition of nitric oxide synthase activity

    Hempel, C., Kohnke, H. N. F., Maretty, L., Jensen, P. Ø., Staalsø, T. & Kurtzhals, J. A. L., Nov 2014, In : Molecular and Biochemical Parasitology. 198, 1, p. 29-36 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Polymorphonuclear leukocytes restrict growth of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients

    Kragh, K. N., Alhede, M., Jensen, P. Ø., Moser, C., Scheike, T., Jacobsen, C. S., Seier Poulsen, S., Eickhardt-Sørensen, S. R., Trøstrup, H., Christoffersen, L., Hougen, H-P., Rickelt, L. F., Kühl, M., Høiby, N. & Bjarnsholt, T., Nov 2014, In : Infection and Immunity. 82, 11, p. 4477-86 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Nitric oxide production by polymorphonuclear leucocytes in infected cystic fibrosis sputum consumes oxygen

    Kolpen, M., Bjarnsholt, T., Moser, C., Hansen, C. R., Rickelt, L. F., Kühl, M., Hempel, C., Pressler, T., Høiby, N. & Jensen, P. Ø., Jul 2014, In : Clinical and Experimental Immunology. 177, 1, p. 310-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published
  52. Published

    Exhaled breath analysis using electronic nose in cystic fibrosis and primary ciliary dyskinesia patients with chronic pulmonary infections

    Joensen, O., Paff, T., Haarman, E. G., Skovgaard, I., Jensen, P. Ø., Bjarnsholt, T. & Nielsen, K. G., 2014, In : P L o S One. 9, 12, p. e115584

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published
  54. Published

    Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection

    Mette, K., Kühl, M., Bjarnsholt, T., Moser, C., Hansen, C. R., Liengaard, L., Kharazmi, A., Pressler, T., Høiby, N. & Jensen, P. Ø., 2014, In : P L o S One. 9, 1, p. e84353

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum

    Line, L., Alhede, M., Mette, K., Kühl, M., Ciofu, O., Bjarnsholt, T., Moser, C., Toyofuku, M., Nomura, N., Høiby, N. & Jensen, P. Ø., 2014, In : Frontiers in Microbiology. 5, p. 554

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. 2013
  57. Published

    Efficacy of a synthetic antimicrobial peptidomimetic versus vancomycin in a Staphylococcus epidermidis device-related murine peritonitis model

    Cavanagh, J. P., Granslo, H. N., Fredheim, E. A., Christophersen, L., Jensen, P. Ø., Thomsen, K., Gennip, M. V., Klingenberg, C., Flaegstad, T. & Moser, C., Sep 2013, In : The Journal of antimicrobial chemotherapy. 68, 9, p. 2106-10 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Sublethal ciprofloxacin treatment leads to rapid development of high-level ciprofloxacin resistance during long-term experimental evolution of Pseudomonas aeruginosa

    Jørgensen, K. M., Wassermann, T., Jensen, P. Ø., Wang, H., Molin, S., Høiby, N. & Ciofu, O., Sep 2013, In : Antimicrobial Agents and Chemotherapy. 57, 9, p. 4215-21 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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