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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2021
  2. E-pub ahead of print

    Gut colonization in preterm infants supplemented with bovine colostrum in the first week of life: An explorative pilot study

    Jiang, P. P., Muk, T., Krych, L., Nielsen, D. S., Khakimov, B., Li, Y., Juhl, S. M., Greisen, G. & Sangild, P. T., 14 May 2021, (E-pub ahead of print) In: Journal of Parenteral and Enteral Nutrition.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Supplemental Insulin-Like Growth Factor-1 and Necrotizing Enterocolitis in Preterm Pigs

    Holgersen, K., Gao, X., Narayanan, R., Gaur, T., Carey, G., Barton, N., Pan, X., Muk, T., Thymann, T. & Sangild, P. T., 4 Feb 2021, In: Frontiers in Pediatrics. 8, p. 602047 602047.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Radiographic Imaging to Evaluate Food Passage Rate in Preterm Piglets as a Model for Preterm Infants

    Kappel, S. S., Sangild, P. T., Scheike, T., Friborg, C. R., Gormsen, M. & Aunsholt, L., 15 Jan 2021, In: Frontiers in Pediatrics. 8, p. 624915 624915.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Gut transit time, using radiological contrast imaging, to predict early signs of necrotizing enterocolitis

    Chen, W., Sun, J., Kappel, S. S., Gormsen, M., Sangild, P. T. & Aunsholt, L., Jan 2021, In: Pediatric Research. 89, 1, p. 127-133 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2020
  7. Published

    Early Use of Antibiotics Is Associated with a Lower Incidence of Necrotizing Enterocolitis in Preterm, Very Low Birth Weight Infants: The NEOMUNE-NeoNutriNet Cohort Study

    Li, Y., Shen, R. L., Ayede, A. I., Berrington, J., Bloomfield, F. H., Busari, O. O., Cormack, B. E., Embleton, N. D., van Goudoever, J. B., Greisen, G., He, Z., Huang, Y., Li, X., Lin, H-C., Mei, J., Meier, P. P., Nie, C., Patel, A. L., Sangild, P. T., Skeath, T., Simmer, K., Uhlenfeldt, S., de Waard, M., Ye, S., Ye, X., Zhang, C., Zhu, Y. & Zhou, P., Dec 2020, In: The Journal of pediatrics. 227, p. 128-134.e2

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Mildly Pasteurized Whey Protein Promotes Gut Tolerance in Immature Piglets Compared with Extensively Heated Whey Protein

    Navis, M., Schwebel, L., Soendergaard Kappel, S., Muncan, V., Sangild, P. T., Abrahamse, E., Aunsholt, L., Thymann, T., van Elburg, R. M. & Renes, I. B., Nov 2020, In: Nutrients. 12, 11

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Beneficial Effect of Mildly Pasteurized Whey Protein on Intestinal Integrity and Innate Defense in Preterm and Near-Term Piglets

    Navis, M., Muncan, V., Sangild, P. T., Møller Willumsen, L., Koelink, P. J., Wildenberg, M. E., Abrahamse, E., Thymann, T., van Elburg, R. M. & Renes, I. B., Apr 2020, In: Nutrients. 12, 4, 1125.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    New generation lipid emulsions increase brain DHA and improve body composition, but not short-term neurodevelopment in parenterally-fed preterm piglets

    Molina, T. L., Stoll, B., Mohammad, M., Mohila, C. A., Call, L., Cui, L., Guthrie, G., Kunichoff, D., Lin, S., Welch-Jernigan, R., Nielsen, J., Premkumar, M., Robinson, J., Smith, V., Teets, H., Obelitz-Ryom, K., Hagan, J., Cruz, S., Lau, P., Puyau, M., Shypailo, R., Manjarin, R., Butte, N., Fang, Z., Olutoye, O., Thymann, T., Sangild, P. & Burrin, D., Mar 2020, In: Brain, Behavior, and Immunity. 85, p. 46-56 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Bovine Colostrum Against Chemotherapy-Induced Gastrointestinal Toxicity in Children With Acute Lymphoblastic Leukemia: A Randomized, Double-Blind, Placebo-Controlled Trial

    Rathe, M., De Pietri, S., Wehner, P. S., Frandsen, T. L., Grell, K., Schmiegelow, K., Sangild, P. T., Husby, S. & Müller, K., Feb 2020, In: Journal of Parenteral and Enteral Nutrition. 44, 2, p. 337-347 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Prenatal inflammation suppresses blood Th1 polarization and gene clusters related to cellular energy metabolism in preterm newborns

    Ren, S., Pan, X., Gao, F., Sangild, P. T. & Nguyen, D. N., Feb 2020, In: FASEB Journal. 34, 2, p. 2896-2911 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Alpha-Lactalbumin Enriched Whey Protein Concentrate to Improve Gut, Immunity and Brain Development in Preterm Pigs

    Nielsen, C. H., Hui, Y., Nguyen, D. N., Ahnfeldt, A. M., Burrin, D. G., Hartmann, B., Heckmann, A. B., Sangild, P. T., Thymann, T. & Bering, S. B., 17 Jan 2020, In: Nutrients. 12, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Diet Modulates the High Sensitivity to Systemic Infection in Newborn Preterm Pigs

    Bæk, O., Brunse, A., Nguyen, D. N., Moodley, A., Thymann, T. & Sangild, P. T., 2020, In: Frontiers in Immunology. 11, p. 1019

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Early Protein Markers of Necrotizing Enterocolitis in Plasma of Preterm Pigs Exposed to Antibiotics

    Jiang, Y-N., Muk, T., Stensballe, A., Nguyen, D. N., Sangild, P. T. & Jiang, P-P., 2020, In: Frontiers in Immunology. 11, 565862.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Postnatal Gut Immunity and Microbiota Development Is Minimally Affected by Prenatal Inflammation in Preterm Pigs

    Pan, X., Zhang, D., Nguyen, D. N., Wei, W., Yu, X., Gao, F. & Sangild, P. T., 2020, In: Frontiers in Immunology. 11, p. 420

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Reply

    Greisen, G., Shen, R. L. & Sangild, P. T., 2020

    Research output: Other contributionResearch

  18. 2019
  19. Published

    Gut and immune effects of bioactive milk factors in preterm pigs exposed to prenatal inflammation

    Ren, S., Hui, Y., Goericke-Pesch, S., Pankratova, S., Kot, W., Pan, X., Thymann, T., Sangild, P. T. & Nguyen, D. N., 1 Jul 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 317, 1, p. G67-G77

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Pathogenesis and biomarkers for necrotizing enterocolitis: Getting any closer?

    Nguyen, D. N. & Sangild, P. T., Jul 2019, In: EBioMedicine. 45, p. 13-14 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Bovine Milk Oligosaccharides with Sialyllactose Improves Cognition in Preterm Pigs

    Obelitz-Ryom, K., Bering, S. B., Overgaard, S. H., Eskildsen, S. F., Ringgaard, S., Olesen, J. L., Skovgaard, K., Pankratova, S., Wang, B., Brunse, A., Heckmann, A. B., Rydal, M. P., Sangild, P. T. & Thymann, T., 14 Jun 2019, In: Nutrients. 11, 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    FortiColos - a multicentre study using bovine colostrum as a fortifier to human milk in very preterm infants: study protocol for a randomised controlled pilot trial

    Ahnfeldt, A. M., Hyldig, N., Li, Y., Kappel, S. S., Aunsholt, L., Sangild, P. T. & Zachariassen, G., 22 May 2019, In: Trials. 20, 1, p. 279

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Milk feed osmolality and adverse events in newborn infants and animals: a systematic review

    Ellis, Z-M., Tan, H. S. G., Embleton, N. D., Sangild, P. T. & van Elburg, R. M., May 2019, In: Archives of Disease in Childhood. Fetal and Neonatal Edition. 104, 3, p. F333-F340

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Preterm Birth Has Effects on Gut Colonization in Piglets Within the First 4 Weeks of Life

    Kamal, S. S., Andersen, A. D., Krych, L., Lauridsen, C., Sangild, P. T., Thymann, T. & Nielsen, D. S., May 2019, In: Journal of Pediatric Gastroenterology and Nutrition. 68, 5, p. 727-733 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Effect of fecal microbiota transplantation route of administration on gut colonization and host response in preterm pigs

    Brunse, A., Martin, L., Rasmussen, T. S., Christensen, L., Skovsted Cilieborg, M., Wiese, M., Khakimov, B., Pieper, R., Nielsen, D. S., Sangild, P. T. & Thymann, T., Mar 2019, In: ISME Journal. 13, 3, p. 720-733 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Oral Supplementation With Bovine Colostrum Prevents Septic Shock and Brain Barrier Disruption During Bloodstream Infection in Preterm Newborn Pigs

    Brunse, A., Worsøe, P., Pors, S. E., Skovgaard, K. & Sangild, P. T., Mar 2019, In: Shock. 51, 3, p. 337-347 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Human Milk Fortification with Bovine Colostrum Is Superior to Formula-Based Fortifiers to Prevent Gut Dysfunction, Necrotizing Enterocolitis, and Systemic Infection in Preterm Pigs

    Sun, J., Li, Y., Pan, X., Nguyen, D. N., Brunse, A., Bojesen, A. M., Rudloff, S., Mortensen, M. S., Burrin, D. G. & Sangild, P. T., Feb 2019, In: Journal of Parenteral and Enteral Nutrition. 43, 2, p. 252-262 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Synbiotics Combined with Glutamine Stimulate Brain Development and the Immune System in Preterm Pigs

    Andersen, A. D., Nguyen, D. N., Langhorn, L., Renes, I. B., van Elburg, R. M., Hartog, A., Tims, S., van de Looij, Y., Sangild, P. T. & Thymann, T., 1 Jan 2019, In: The Journal of Nutrition. 149, 1, p. 36-45 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Bovine Colostrum Before or After Formula Feeding Improves Systemic Immune Protection and Gut Function in Newborn Preterm Pigs

    Li, Y., Pan, X., Nguyen, D. N., Ren, S., Moodley, A. & Sangild, P. T., 2019, In: Frontiers in Immunology. 10, p. 3062

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Growth Restriction and Systemic Immune Development in Preterm Piglets

    Bæk, O., Sangild, P. T., Thymann, T. & Nguyen, D. N., 2019, In: Frontiers in Immunology. 10, p. 2402

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Physical Activity and Spatial Memory Are Minimally Affected by Moderate Growth Restriction in Preterm Piglets

    Cao, M., Brunse, A., Thymann, T. & Sangild, P. T., 2019, In: Developmental Neuroscience. 41, 3-4, p. 247-254 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Rapid Proteome Changes in Plasma and Cerebrospinal Fluid Following Bacterial Infection in Preterm Newborn Pigs

    Muk, T., Stensballe, A., Pankratova, S., Nguyen, D. N., Brunse, A., Sangild, P. T. & Jiang, P-P., 2019, In: Frontiers in Immunology. 10, p. 2651

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Time to Full Enteral Feeding for Very Low-Birth-Weight Infants Varies Markedly Among Hospitals Worldwide But May Not Be Associated With Incidence of Necrotizing Enterocolitis: The NEOMUNE-NeoNutriNet Cohort Study

    de Waard, M., Li, Y., Zhu, Y., Ayede, A. I., Berrington, J., Bloomfield, F. H., Busari, O. O., Cormack, B. E., Embleton, N. D., van Goudoever, J. B., Greisen, G., He, Z., Huang, Y., Li, X., Lin, H-C., Mei, J., Meier, P. P., Nie, C., Patel, A. L., Ritz, C., Sangild, P. T., Skeath, T., Simmer, K., Tongo, O. O., Uhlenfeldt, S. S., Ye, S., Ye, X., Zhang, C. & Zhou, P., 2019, In: Journal of Parenteral and Enteral Nutrition. 43, 5, p. 658-667 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2018
  35. Published

    Necrotizing enterocolitis is associated with acute brain responses in preterm pigs

    Sun, J., Pan, X., Christiansen, L. I., Yuan, X-L., Skovgaard, K., Chatterton, D. E. W., Kaalund, S. S., Gao, F., Sangild, P. T. & Pankratova, S., 9 Jun 2018, In: Journal of Neuroinflammation. 15, 1, p. 180

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Bovine Colostrum For Preterm Infants in the First Days of Life: A Randomized Controlled Pilot Trial

    Juhl, S. M., Ye, X., Zhou, P., Li, Y., Iyore, E. O., Zhang, L., Jiang, P., van Goudoever, J. B., Greisen, G. & Sangild, P. T., 2018, In: Journal of Pediatric Gastroenterology and Nutrition. 66, 3, p. 471-478

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Minimal Enteral Nutrition to Improve Adaptation After Intestinal Resection in Piglets and Infants

    Aunsholt, L., Qvist, N., Sangild, P. T., Vegge, A., Stoll, B., Burrin, D. G., Jeppesen, P. B., Eriksen, T., Husby, S. & Thymann, T., 2018, In: Journal of Parenteral and Enteral Nutrition. 42, 2, p. 446-454

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Rapid Postnatal Adaptation of Neurodevelopment in Pigs Born Late Preterm

    Holme Nielsen, C., Bladt Brandt, A., Thymann, T., Obelitz-Ryom, K., Jiang, P., Vanden Hole, C., van Ginneken, C., Pankratova, S. & Sangild, P. T., 2018, In: Developmental Neuroscience. 40, 5-6, p. 586-600 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2017
  40. Published

    Chemotherapeutic treatment reduces circulating levels of surfactant protein-D in children with acute lymphoblastic leukemia

    Rathe, M., Sorensen, G. L., Wehner, P. S., Holmskov, U., Sangild, P. T., Schmiegelow, K., Müller, K. & Husby, S., Mar 2017, In: Pediatric Blood and Cancer. 64, 3, p. e26253

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    A Stepwise, Pilot Study of Bovine Colostrum to Supplement the First Enteral Feeding in Preterm Infants (Precolos): Study Protocol and Initial Results

    Li, Y., Juhl, S. M., Ye, X., Shen, R. L., Iyore, E. O., Dai, Y., Sangild, P. T. & Greisen, G. O., 2017, In: Frontiers in Pediatrics. 5, p. 42

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 2016
  43. Published

    Enteral but not parenteral antibiotics enhance gut function and prevent necrotizing enterocolitis in formula-fed newborn preterm pigs

    Birck, M. M., Nguyen, D. N., Cilieborg, M. S., Kamal, S. S., Nielsen, D. S., Damborg, P., Olsen, J., Lauridsen, C., Sangild, P. T. & Thymann, T., 17 Dec 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 5, p. G323-33

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Spray Dried, Pasteurised Bovine Colostrum Protects Against Gut Dysfunction and Inflammation in Preterm Pigs

    Støy, A. C. F., Sangild, P. T., Skovgaard, K., Thymann, T., Bjerre, M., Chatterton, D. E. W., Purup, S., Boye, M. & Heegaard, P. M. H., 7 Dec 2016, In: Journal of Pediatric Gastroenterology and Nutrition. 63, 2, p. 280-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Doxorubicin-Induced Gut Toxicity in Piglets Fed Bovine Milk and Colostrum

    Shen, R. L., Rathe, M., Jiang, P., Pontoppidan, P. E. L., Heegaard, P. M. H., Müller, K. & Sangild, P. T., Dec 2016, In: Journal of Pediatric Gastroenterology and Nutrition. 63, 6, p. 698-707 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Milk diets influence doxorubicin-induced intestinal toxicity in piglets

    Shen, R. L., Pontoppidan, P. E. L., Rathe, M., Jiang, P., Hansen, C. F., Buddington, R. K., Heegaard, P. M. H., Müller, K. & Sangild, P. T., 1 Aug 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 311, 2, p. G324-33

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Rapid gut growth but persistent delay in digestive function in the postnatal period of preterm pigs

    Hansen, C. F., Thymann, T., Andersen, A. D., Holst, J. J., Hartmann, B., Hilsted, L., Langhorn, L., Jelsing, J. & Sangild, P. T., 15 Apr 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 8, p. G550-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Delayed growth, motor function and learning in preterm pigs during early postnatal life

    Andersen, A. D., Sangild, P. T., Munch, S. L., van der Beek, E. M., Renes, I. B., Ginneken, C. V., Greisen, G. O. & Thymann, T., 15 Mar 2016, In: A J P: Regulatory, Integrative and Comparative Physiology (Online). 310, 6, p. R481-92

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Provision of Amniotic Fluid During Parenteral Nutrition Increases Weight Gain With Limited Effects on Gut Structure, Function, Immunity, and Microbiology in Newborn Preterm Pigs

    Østergaard, M. V., Shen, R. L., Støy, A. C. F., Skovgaard, K., Krych, Ł., Leth, S. S., Nielsen, D. S., Hartmann, B., Bering, S. B., Schmidt, M. & Sangild, P. T., 2016, In: Journal of Parenteral and Enteral Nutrition. 40, 4, p. 552-66

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 2015
  51. Published

    Preterm Birth Reduces Nutrient Absorption With Limited Effect on Immune Gene Expression and Gut Colonization in Pigs

    Østergaard, M. V., Cilieborg, M. S., Skovgaard, K., Schmidt, M., Sangild, P. T. & Bering, S. B., Oct 2015, In: Journal of Pediatric Gastroenterology and Nutrition. 61, 4, p. 481-90 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs

    Shen, R. L., Thymann, T., Østergaard, M. V., Støy, A. C. F., Krych, Ł., Nielsen, D. S., Lauridsen, C., Hartmann, B., Holst, J. J., Burrin, D. G. & Sangild, P. T., 1 Sep 2015, In: A J P: Gastrointestinal and Liver Physiology (Online). 309, 5, p. G310-23

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Physical activity level is impaired and diet dependent in preterm newborn pigs

    Cao, M., Andersen, A. D., Van Ginneken, C., Shen, R. L., Petersen, S. O., Thymann, T., Jing, J. & Sangild, P. T., Aug 2015, In: Pediatric Research. 78, 2, p. 137-44 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Prematurity Reduces Functional Adaptation to Intestinal Resection in Piglets

    Aunsholt, L., Thymann, T., Qvist, N., Sigalet, D., Husby, S. & Sangild, P. T., Aug 2015, In: Journal of Parenteral and Enteral Nutrition. 39, 6, p. 668-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Parenteral lipids and partial enteral nutrition affect hepatic lipid composition but have limited short term effects on formula-induced necrotizing enterocolitis in preterm piglets

    Vegge, A., Thymann, T., Lauritzen, L., Bering, S. B., Wiinberg, B. & Sangild, P. T., Apr 2015, In: Clinical nutrition (Edinburgh, Scotland). 34, 2, p. 219-28 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Glucose transport by epithelia prepared from harvested enterocytes

    Kimura, Y., van der Merwe, M., Bering, S. B., Penmatsa, H., Conoley, V. G., Sangild, P. T., Naren, A. P. & Buddington, R. K., Jan 2015, In: Cytotechnology. 67, 1, p. 39-49 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Introducing enteral feeding induces intestinal subclinical inflammation and respective chromatin changes in preterm pigs

    Willems, R., Krych, L., Rybicki, V., Jiang, P., Sangild, P. T., Shen, R. L., Hensel, K. O., Wirth, S., Postberg, J. & Jenke, A. C., 2015, In: Epigenomics. 7, 4, p. 553-65 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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