Personal profile
Research areas
My research focus on diet and genetics of the Greenlandic Inuit in relation to metabolic health.
Current research
I am currently working with a genetic variant that only excists in Arctic populations. The variant results in an inabilty to digest sucrose - meaning that if you inherited this genetic variant from your parents, you cannot tolerate sugar. We recently found out that Greenlanders who are sucrose-intolerant are metabolically healthier. With my current project I want to figure out why. I'm therefore currently located in Nuuk to do a dietary intervention. I'm affiliated with Steno Diabetes Center Greenland, and working at Illimartusarfik (University of Greenland).
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Collaborations and top research areas from the last five years
Research output
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The prevalence of diabetic neuropathy in Greenland and its association with Inuit genetic ancestry - a cross-sectional study
Christensen, M. M. B., Hansen, C. S., Fleischer, J., Senftleber, N., Stæger, F. F., Hansen, T., Witte, D. R. & Jørgensen, M. E., Nov 2025, In: Journal of Diabetes and its Complications. 39, 11, p. 109179 109179.Research output: Contribution to journal › Journal article › Research › peer-review
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GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal
Senftleber, N. K., Andersen, M. K., Jørsboe, E., Stæger, F. F., Nøhr, A. K., Garcia-Erill, G., Meisner, J., Santander, C. G., Balboa, R. F., Gilly, A., Bjerregaard, P., Larsen, C. V. L., Grarup, N., Jørgensen, M. E., Zeggini, E., Moltke, I., Hansen, T. & Albrechtsen, A., Feb 2024, In: European journal of human genetics : EJHG. 32, 2, p. 215-223 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus) -
Healthcare Burden in Greenland of Gastrointestinal Symptoms in Adults with Inherited Loss of Sucrase-Isomaltase Function
Andersen, K., Hansen, T., Jørgensen, M. E. & Senftleber, N., 2024, In: The Application of Clinical Genetics. 17, p. 15-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
4 Citations (Scopus) -
Personal experiences of living with sucrose intolerance and attitudes towards genetic research in Greenland - a user study
Isidor, S., Senftleber, N., Schnoor, C., Pedersen, K. S., Seibæk, L., Jørgensen, M. E. & Marcussen, J., Dec 2024, In: International Journal of Circumpolar Health. 83, 1, p. 2383023 2383023.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Type 2 diabetes in Greenland: prevalence and risk factors
Harder, M., Bjerregaard, P., Jørgensen, M. E., Senftleber, N., Byberg, S. & Hansen, T., 2024, In: Diabetologia. 67, Suppl 1, 313.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review