Niels Høiby

2024

The microenvironment in antibiotic susceptibility testing

Høiby, N., Moser, C. & Ciofu, O., 2 Apr 2024, (E-pub ahead of print) In: APMIS - Journal of Pathology, Microbiology and Immunology.

Research output: Contribution to journal › Review › peer-review

2022

Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection - significance of macrolide treatment

Thomsen, K., Kobayashi, O., Kishi, K., Shirai, R., Østrup Jensen, P., Heydorn, A., Hentzer, M., Calum, H., Christophersen, L., Høiby, N. & Moser, C., Jul 2022, In: APMIS - Journal of Pathology, Microbiology and Immunology. 130, 7, p. 458-476 19 p., 13161.

Research output: Contribution to journal › Review › peer-review

9 Citations (Scopus)

Combination and nanotechnology based pharmaceutical strategies for combating respiratory bacterial biofilm infections

Zhang, L., Bera, H., Wang, H., Wang, J., Guo, Y., Shi, C., Cun, D., Moser, C., Høiby, N. & Yang, M., 25 Mar 2022, In: International Journal of Pharmaceutics. 616, 121507.

Research output: Contribution to journal › Review › peer-review

Immune Response to Biofilm Growing Pulmonary Pseudomonas aeruginosa Infection

Thomsen, K., Høiby, N., Jensen, P. Ø., Ciofu, O. & Moser, C., 24 Aug 2022, In: Biomedicines. 10, 9, p. 1-14 14 p., 2064.

Research output: Contribution to journal › Review › peer-review

Murine burn lesion model for studying acute and chronic wound infections

Calum, H., Trøstrup, H., Laulund, A. S., Thomsen, K., Christophersen, L., Høiby, N. & Moser, C., Jul 2022, In: APMIS - Journal of Pathology, Microbiology and Immunology. 130, 7, p. 477-490 14 p., 13228.

Research output: Contribution to journal › Review › peer-review

3 Citations (Scopus)

Potential Advances of Adjunctive Hyperbaric Oxygen Therapy in Infective Endocarditis

Lerche, C. J., Schwartz, F., Pries-Heje, M. M., Fosbøl, E. L., Iversen, K., Jensen, P. Ø., Høiby, N., Hyldegaard, O., Bundgaard, H. & Moser, C., 3 Feb 2022, In: Frontiers in cellular and infection microbiology. 12, p. 1-12 12 p., 805964.

Research output: Contribution to journal › Review › peer-review

7 Citations (Scopus)

Tolerance and resistance of microbial biofilms

Ciofu, O., Moser, C., Jensen, P. Ø. & Høiby, N., Oct 2022, In: Nature Reviews. Microbiology. 20, 10, p. 621-635 15 p.

Research output: Contribution to journal › Review › peer-review

407 Citations (Scopus)

2021

Anti-biofilm Approach in Infective Endocarditis Exposes New Treatment Strategies for Improved Outcome

Lerche, C. J., Schwartz, F., Theut, M., Fosbøl, E. L., Iversen, K., Bundgaard, H., Høiby, N. & Moser, C., 18 Jun 2021, In: Frontiers in Cell and Developmental Biology. 9, 643335.

Research output: Contribution to journal › Review › peer-review

35 Citations (Scopus)

Pandemics: past, present, future: That is like choosing between cholera and plague

Høiby, N., Jul 2021, In: APMIS - Journal of Pathology, Microbiology and Immunology. 129, 7, p. 352-371 20 p.

Research output: Contribution to journal › Review › peer-review

26 Citations (Scopus)

2020

Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air

Jensen, P. Ø., Møller, S. A., Lerche, C. J., Moser, C., Bjarnsholt, T., Ciofu, O., Faurholt-Jepsen, D., Høiby, N. & Kolpen, M., Dec 2020, In: Biofilm. 1, p. 100008

Research output: Contribution to journal › Review › peer-review

2019

Antibiotic therapy as personalized medicine - general considerations and complicating factors

Moser, C., Lerche, C. J., Thomsen, K., Hartvig, T., Schierbeck, J., Jensen, P. Ø., Ciofu, O. & Høiby, N., May 2019, In: APMIS - Journal of Pathology, Microbiology and Immunology. 127, 5, p. 361-371 11 p.

Research output: Contribution to journal › Review › peer-review

2018

A systematic review of studies on the faecal microbiota in anorexia nervosa: future research may need to include microbiota from the small intestine

Schwensen, H. F., Kan, C., Treasure, J., Høiby, N. & Sjögren, M., 2018, In: Eating and Weight Disorders. 23, 4, p. 399-418 19 p.

Research output: Contribution to journal › Review › peer-review

33 Citations (Scopus)

Mechanisms of humoral immune response against Pseudomonas aeruginosa biofilm infection in cystic fibrosis

Mauch, R. M., Jensen, P. Ø., Moser, C., Levy, C. E. & Høiby, N., Mar 2018, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 17, 2, p. 143-152 10 p.

Research output: Contribution to journal › Review › peer-review

37 Citations (Scopus)

The importance of early diagnosis of Mycobacterium abscessus complex in patients with cystic fibrosis

Ravnholt, C., Kolpen, M., Skov, M., Moser, C., Katzenstein, T. L., Pressler, T., Høiby, N. & Qvist, T., Dec 2018, In: APMIS - Journal of Pathology, Microbiology and Immunology. 126, 12, p. 885-891 7 p.

Research output: Contribution to journal › Review › peer-review

2017

A short history of microbial biofilms and biofilm infections

Høiby, N., Apr 2017, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 125, 4, p. 272-275 4 p.

Research output: Contribution to journal › Review › peer-review

132 Citations (Scopus)

Biofilms and host response - helpful or harmful

Moser, C., Pedersen, H. T., Lerche, C. J., Kolpen, M., Line, L., Thomsen, K., Høiby, N. & Jensen, P. Ø., Apr 2017, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 125, 4, p. 320-338 19 p.

Research output: Contribution to journal › Review › peer-review

113 Citations (Scopus)

Diagnosis of biofilm infections in cystic fibrosis patients

Høiby, N., Bjarnsholt, T., Moser, C., Jensen, P. Ø., Kolpen, M., Qvist, T., Aanaes, K., Pressler, T., Skov, M. & Ciofu, O., Apr 2017, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 125, 4, p. 339-343 5 p.

Research output: Contribution to journal › Review › peer-review

68 Citations (Scopus)

Sinus bacteriology in patients with cystic fibrosis or primary ciliary dyskinesia: A systematic review

Møller, M. E., Alanin, M. C., Grønhøj, C., Aanæs, K., Høiby, N. & von Buchwald, C., 1 Sept 2017, In: American Journal of Rhinology and Allergy. 31, 5, p. 293-298 6 p.

Research output: Contribution to journal › Review › peer-review

20 Citations (Scopus)

2016

Animal models of chronic wound care: the application of biofilms in clinical research

Trøstrup, H., Thomsen, K., Calum, H. P., Høiby, N. & Moser, C. E., 2016, In: Dove press (Chronic wound care management and research. 3, p. 123-132

Research output: Contribution to journal › Review › peer-review

2014

Effects of radix ginseng on microbial infections: a narrative review

Wu, H., Høiby, N., Yang, L., Givskov, M. & Song, Z., Apr 2014, In: Journal of Traditional Chinese Medicine. 34, 2, p. 227-33 7 p.

Research output: Contribution to journal › Review › peer-review

14 Citations (Scopus)

2010

Antibiotic resistance of bacterial biofilms

Høiby, N., Bjarnsholt, T., Givskov, M., Molin, S. & Ciofu, O., 1 Apr 2010, In: International Journal of Antimicrobial Agents. 35, 4, p. 322-32 11 p.

Research output: Contribution to journal › Review › peer-review

2437 Citations (Scopus)

Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

Burmølle, M., Thomsen, T. R., Fazli, M., Dige, I., Christensen, L. H., Homøe, P., Tvede, M., Nyvad, B., Tolker-Nielsen, T., Givskov, M., Moser, C., Kirketerp-Møller, K., Johansen, H. K., Høiby, N., Jensen, P. Ø., Sørensen, S. J. & Bjarnsholt, T., 1 Aug 2010, In: F E M S Immunology and Medical Microbiology. 59, 3, p. 324-36 13 p.

Research output: Contribution to journal › Review › peer-review

326 Citations (Scopus)

Interference of Pseudomonas aeruginosa signalling and biofilm formation for infection control

Bjarnsholt, T., Tolker-Nielsen, T., Høiby, N. & Givskov, M., 1 Jan 2010, In: Expert Reviews in Molecular Medicine. 12, p. e11

Research output: Contribution to journal › Review › peer-review

99 Citations (Scopus)

Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies

Hassett, D. J., Korfhagen, T. R., Irvin, R. T., Schurr, M. J., Sauer, K., Lau, G. W., Sutton, M. D., Yu, H. & Hoiby, N., Feb 2010, In: Expert Opinion on Therapeutic Targets. 14, 2, p. 117-30 14 p.

Research output: Contribution to journal › Review › peer-review

Pseudomonas aeruginosa biofilms in cystic fibrosis

Høiby, N., Ciofu, O. & Bjarnsholt, T., 1 Nov 2010, In: Future Microbiology. 5, p. 1663-74 12 p.

Research output: Contribution to journal › Review › peer-review

516 Citations (Scopus)

2009

Inhaled medication and inhalation devices for lung disease in patients with cystic fibrosis: A European consensus

consensus working group & Høiby, N. (Member of study group), Sept 2009, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 8, 5, p. 295-315 21 p.

Research output: Contribution to journal › Review › peer-review

2007

Class A carbapenemases

Walther-Rasmussen, J. & Høiby, N., Sept 2007, In: The Journal of antimicrobial chemotherapy. 60, 3, p. 470-82 13 p.

Research output: Contribution to journal › Review › peer-review

Isolation measures for prevention of infection with respiratory pathogens in cystic fibrosis: a systematic review?

Høiby, N. & Johansen, H. K., Apr 2007, In: The Journal of hospital infection. 65, 4, p. 374-5; author reply 375-6

Research output: Contribution to journal › Review › peer-review

2006

OXA-type carbapenemases

Walther-Rasmussen, J. & Høiby, N., Mar 2006, In: The Journal of antimicrobial chemotherapy. 57, 3, p. 373-83 11 p.

Research output: Contribution to journal › Review › peer-review

2005

Eradication of early Pseudomonas aeruginosa infection

Høiby, N., Frederiksen, B. & Pressler, T., Aug 2005, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 4 Suppl 2, p. 49-54 6 p.

Research output: Contribution to journal › Review › peer-review

Microbial pathogenesis and biofilm development

Reisner, A., Høiby, N., Tolker-Nielsen, T. & Molin, S., 2005, In: Contributions to microbiology. 12, p. 114-131 18 p.

Research output: Contribution to journal › Review › peer-review

2004

Cefotaximases (CTX-M-ases), an expanding family of extended-spectrum beta-lactamases

Walther-Rasmussen, J. & Høiby, N., Mar 2004, In: Canadian journal of microbiology. 50, 3, p. 137-65 29 p.

Research output: Contribution to journal › Review › peer-review

Early intervention and prevention of lung disease in cystic fibrosis: a European consensus

Consensus Study Group, Jun 2004, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 3, 2, p. 67-91 25 p.

Research output: Contribution to journal › Review › peer-review

2002

New antimicrobials in the management of cystic fibrosis

Høiby, N., Feb 2002, In: The Journal of antimicrobial chemotherapy. 49, 2, p. 235-8 4 p.

Research output: Contribution to journal › Review › peer-review

Plasmid-borne AmpC beta-lactamases

Walther-Rasmussen, J. & Høiby, N., Jun 2002, In: Canadian journal of microbiology. 48, 6, p. 479-93 15 p.

Research output: Contribution to journal › Review › peer-review

Understanding bacterial biofilms in patients with cystic fibrosis: current and innovative approaches to potential therapies

Høiby, N., Dec 2002, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 1, 4, p. 249-54 6 p.

Research output: Contribution to journal › Review › peer-review

2001

Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth

Høiby, N., Krogh Johansen, H., Moser, C., Song, Z., Ciofu, O. & Kharazmi, A., Jan 2001, In: Microbes and Infection. 3, 1, p. 23-35 13 p.

Research output: Contribution to journal › Review › peer-review

2000

Antibiotic therapy against Pseudomonas aeruginosa in cystic fibrosis: a European consensus

Döring, G., Conway, S. P., Heijerman, H. G., Hodson, M. E., Høiby, N., Smyth, A. & Touw, D. J., Oct 2000, In: The European respiratory journal. 16, 4, p. 749-67 19 p.

Research output: Contribution to journal › Review › peer-review

A ten year review of colomycin

Littlewood, J. M., Koch, C., Lambert, P. A., Høiby, N., Elborn, J. S., Conway, S. P., Dinwiddie, R. & Duncan-Skingle, F., Jul 2000, In: Respiratory medicine. 94, 7, p. 632-40 9 p.

Research output: Contribution to journal › Review › peer-review

Diagnosis and treatment of cystic fibrosis

Koch, C. & Høiby, N., 2000, In: Respiration; international review of thoracic diseases. 67, 3, p. 239-47 9 p.

Research output: Contribution to journal › Review › peer-review

Prospects for the prevention and control of pseudomonal infection in children with cystic fibrosis

Høiby, N., 2000, In: Paediatric Drugs. 2, 6, p. 451-63 13 p.

Research output: Contribution to journal › Review › peer-review

1997

Vaccination promotes TH1-like inflammation and survival in chronic Pseudomonas aeruginosa pneumonia. A new prophylactic principle

Johansen, H. K., Cryz, S. J., Hougen, H. P., Moser, C. & Høiby, N., Feb 1997, In: Behring Institute Mitteilungen. 98, p. 269-73 5 p.

Research output: Contribution to journal › Review › peer-review

1996

Use of carbapenems and other antibiotics for pulmonary infections in patients with cystic fibrosis

Høiby, N., Ciofu, O., Jensen, T., Pressler, T., Johansen, H. K. & Koch, C., Aug 1996, In: The Pediatric infectious disease journal. 15, 8, p. 738-43 6 p.

Research output: Contribution to journal › Review › peer-review

1995

Epidemiologic aspects on antibiotic resistance

Høiby, N., 1995, In: Microbial drug resistance (Larchmont, N.Y.). 1, 2, p. 137-42 6 p.

Research output: Contribution to journal › Review › peer-review

1994

Biofilm, fremmedlegemer og kroniske infektioner

Translated title of the contribution: Biofilm, foreign bodies and chronic infectionsHøiby, N., Espersen, F., Fomsgaard, A., Giwercman, B., Jensen, E. T., Johansen, H. K., Koch, C., Kronborg, G., Pedersen, S. S. & Pressler, T., 10 Oct 1994, In: Ugeskrift for Laeger. 156, 41, p. 5998-6005 8 p.

Research output: Contribution to journal › Review › peer-review