Personal profile
Expertises
Histology; Microscopy; Stereology; Animal behavior; Perfusion fixation; Stereotaxic surgery, Microinjection, Brain dissection and sectioning; Autoradiography; in situ hybridization.
Main research areas
Neurodegenerative disorders; Psychiatric diseases, Transgenic mouse models
Current research
Using Stereology (the optical fractionator, Cavalieri’s principle, the rotator and the proportionator techniques) I have studied structural changes in psychiatric diseases and neurodegenerative disorders. I am currently using stereology to examine whether there are specific cellular changes in in the cerebellum in patients with Parkinson’s disease and Multiple System Atrophy.? Furthermore, I am studying the regulation of mRNA and protein level specific receptor systems following depression-like behaviour and electroconvulsive stimulation.
Potential conflicts of interest
There are no conflicts of interest
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Collaborations and top research areas from the last five years
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Mouse model of atypical DAT deficiency syndrome uncovers dopamine dysfunction associated with parkinsonism and ADHD
Herborg, F., Konrad, L. K., Jørgensen, S. H., Lilja, J. H., Delignat-Lavaud, B., Posselt, L. P., Pugh, C. F., Bach, S. A., Ratner, C. F., Awadallah, N., Pino, J. A., Berlin, F., Ejdrup, A. L., Olesen, M. V., Rickhag, M., Holst, B., Aznar, S., Mayer, F. P., Woldbye, D. & Torres, G. & 2 others, , 16 Mar 2026, In: The Journal of clinical investigation. 136, 6Research output: Contribution to journal › Journal article › Research › peer-review
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Systemic inflammation activates coagulation and immune cell infiltration pathways in brains with propagating α-synuclein fibril aggregates
Laursen, A.-L. S., Olesen, M. V., Folke, J., Brudek, T., Knecht, L. H., Sotty, F., Lambertsen, K. L., Fog, K., Dalgaard, L. T. & Aznar, S., Jun 2024, In: Molecular and Cellular Neurosciences. 129, p. 103931 103931.Research output: Contribution to journal › Journal article › Research › peer-review
4 Citations (Scopus) -
Quantitative cellular changes in multiple system atrophy brains
Andersen, A. M., Kaalund, S. S., Marner, L., Salvesen, L., Pakkenberg, B. & Olesen, M. V., Dec 2023, In: Neuropathology and Applied Neurobiology. 49, 6, p. e12941 e12941.Research output: Contribution to journal › Review › peer-review
5 Citations (Scopus) -
3D Ultrasound versus Computed Tomography for Tumor Volume Measurement Compared to Gross Pathology-A Pilot Study on an Animal Model
Makouei, F., Ewertsen, C., Agander, T. K., Olesen, M. V., Pakkenberg, B. & Todsen, T., 19 Dec 2022, In: Journal of imaging. 8, 12, 329.Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus) -
Is There a Correlation Between the Number of Brain Cells and IQ?
Songthawornpong, N., Teasdale, T. W., Olesen, M. V. & Pakkenberg, B., 1 Jan 2021, In: Cerebral Cortex. 31, 1, p. 650-657 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus)