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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2021
  2. Published

    Postoperative complications: an observational study of trends in the United States from 2012 to 2018

    Dencker, E. E., Bonde, A., Troelsen, A., Varadarajan, K. M. & Sillesen, M., 6 Nov 2021, In: BMC Surgery. 21, 1, 393.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Using machine learning for predicting intensive care unit resource use during the COVID-19 pandemic in Denmark

    Lorenzen, S. S., Nielsen, M., Jimenez-Solem, E., Petersen, T. S., Perner, A., Thorsen-Meyer, H-C., Igel, C. & Sillesen, M., 23 Sep 2021, In: Scientific Reports. 11, 1, p. 18959 18959.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Assessing the utility of deep neural networks in predicting postoperative surgical complications: a retrospective study

    Bonde, A., Varadarajan, K. M., Bonde, N., Troelsen, A., Muratoglu, O. K., Malchau, H., Yang, A. D., Alam, H. & Sillesen, M., Aug 2021, In: The Lancet. Digital health. 3, 8, p. e471-e485 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Hemorrhage and saline resuscitation are associated with epigenetic and proteomic reprogramming in the rat lung

    Bonde, A., Eskesen, T. G., Steinmetz, J., Schoof, E. M., Blicher, L. H. D., Rasmussen, L. S. & Sillesen, M., Aug 2021, In: Injury. 52, 8, p. 2095-2103 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Developing and validating COVID-19 adverse outcome risk prediction models from a bi-national European cohort of 5594 patients

    Jimenez-Solem, E., Petersen, T. S., Hansen, C., Hansen, C., Lioma, C., Igel, C., Boomsma, W., Krause, O., Lorenzen, S., Selvan, R., Petersen, J., Nyeland, M. E., Ankarfeldt, M. Z., Virenfeldt, G. M., Winther-Jensen, M., Linneberg, A., Ghazi, M. M., Detlefsen, N., Lauritzen, A. D., Smith, A. G., de Bruijne, M., Ibragimov, B., Petersen, J., Lillholm, M., Middleton, J., Mogensen, S. H., Thorsen-Meyer, H-C., Perner, A., Helleberg, M., Kaas-Hansen, B. S., Bonde, M., Bonde, A., Pai, A., Nielsen, M. & Sillesen, M., 5 Feb 2021, In: Scientific Reports. 11, 1, p. 3246 3246.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2020
  8. Published

    Ketamine for rapid sequence intubation in adult trauma patients: A retrospective observational study

    Baekgaard, J. S., Eskesen, T. G., Lee, J. M., Ottosen, C. I., Gyldenkaerne, K. B., Garoussian, J., Christensen, R. E., Sillesen, M., King, D. R., Velmahos, G. C., Rasmussen, L. S. & Steinmetz, J., 1 Oct 2020, In: Acta Anaesthesiologica Scandinavica. 64, 9, p. 1234-1242 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Smoking and risk of surgical bleeding: nationwide analysis of 5,452,411 surgical cases

    Nordestgaard, A. T., Rasmussen, L. S., Sillesen, M., Steinmetz, J., King, D. R., Saillant, N., Kaafarani, H. M. & Velmahos, G. C., Aug 2020, In: Transfusion. 60, 8, p. 1689-1699 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Identification of a new genetic variant associated with cholecystitis: a multicenter genome-wide association study

    Bonde, A., Gaitanidis, A., Breen, K., El Hechi, M., Nederpelt, C., Christensen, M., Kokoroskos, N., Mendoza, A., Velmahos, G., Sillesen, M., Farhat, M. R. & Kaafarani, H. M. A., 1 Jul 2020, In: The journal of trauma and acute care surgery. 89, 1, p. 173-178 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Red blood cell transfusion in surgery: an observational study of the trends in the USA from 2011 to 2016

    Nordestgaard, A. T., Rasmussen, L. S., Sillesen, M., Steinmetz, J., Eid, A. I., Meier, K., Kaafarani, H. M. A. & Velmahos, G. C., Apr 2020, In: Anaesthesia. 75, 4, p. 455-463

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2019
  13. Published

    Ketamine as a Rapid Sequence Induction Agent in the Trauma Population: A Systematic Review

    Baekgaard, J. S., Eskesen, T. G., Sillesen, M., Rasmussen, L. S. & Steinmetz, J., Mar 2019, In: Anesthesia and Analgesia. 128, 3, p. 504-510 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    Effect of hospital-admission volume on outcomes following acute non-variceal upper gastrointestinal bleeding

    Schmidt, M. S., Preisler, L., Fabricius, R., Svenningsen, P., Hillingsø, J., Svendsen, L. B. & Sillesen, M., Feb 2019, In: Danish Medical Journal. 66, 2, p. A5531

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2018
  16. Published

    The effect of fluid resuscitation strategy on monocyte and T-cell surface markers

    Bonde, A., Kirial, R., Svenningsen, P. & Sillesen, M., Oct 2018, In: The Journal of surgical research. 230, p. 20-27 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Transfusion Strategies are Associated with Epigenetic Changes Following Blunt Trauma

    Sillesen, M., Li, Y. & Alam, H. B., Jul 2018, In: Shock. 50, 1, p. 24-30 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Different resuscitation strategies and novel pharmacologic treatment with valproic acid in traumatic brain injury

    Dekker, S. E., Nikolian, V. C., Sillesen, M., Bambakidis, T., Schober, P. & Alam, H. B., Apr 2018, In: Journal of Neuroscience Research. 96, 4, p. 711-719 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Tubastatin A prevents hemorrhage-induced endothelial barrier dysfunction

    Bruhn, P. J., Nikolian, V. C., Halaweish, I., Chang, Z., Sillesen, M., Liu, B., Li, Y. & Alam, H. B., Feb 2018, In: The journal of trauma and acute care surgery. 84, 2, p. 386-392 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2017
  21. Published

    Self-evaluated competence in trauma reception

    Steinthorsdottir, K. J., Svenningsen, P., Fabricius, R., Svendsen, L. B., Hillingsø, J. & Sillesen, M., Nov 2017, In: Danish Medical Journal. 64, 11, p. A5420

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Valproic acid modulates platelet and coagulation function ex vivo

    Bambakidis, T., Dekker, S. E., Halaweish, I., Liu, B., Nikolian, V. C., Georgoff, P. E., Piascik, P., Li, Y., Sillesen, M. & Alam, H. B., Sep 2017, In: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis. 28, 6, p. 479-484 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Fresh Frozen Plasma Modulates Brain Gene Expression in a Swine Model of Traumatic Brain Injury and Shock: A Network Analysis

    Sillesen, M., Bambakidis, T., Dekker, S. E., Li, Y. & Alam, H. B., Jan 2017, In: Journal of the American College of Surgeons. 224, 1, p. 49-58 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published
  25. Published

    The effect of resuscitation strategy on the longitudinal immuno-inflammatory response to blunt trauma

    Bonde, A., Nordestgaard, A. T., Kirial, R., Svenningsen, P. & Sillesen, M., 2017, In: Injury. 48, 12, p. 2670-2674

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2016
  27. Published
  28. Published

    Resuscitation with Valproic Acid Alters Inflammatory Genes in a Porcine Model of Combined Traumatic Brain Injury and Hemorrhagic Shock

    Bambakidis, T., Dekker, S. E., Sillesen, M., Liu, B., Johnson, C. N., Jin, G., de Vries, H. E., Li, Y. & Alam, H. B., 15 Aug 2016, In: Journal of Neurotrauma. 33, 16, p. 1514-21 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published
  30. Published

    Histone deactylase gene expression profiles are associated with outcomes in blunt trauma patients

    Sillesen, M., Bambakidis, T., Dekker, S. E., Fabricius, R., Svenningsen, P., Bruhn, P. J., Svendsen, L. B., Hillingsø, J. & Alam, H. B., 2016, In: The journal of trauma and acute care surgery. 80, 1, p. 26-33

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published
  32. 2015
  33. Published

    Fresh Frozen Plasma Resuscitation Provides Neuroprotection Compared to Normal Saline in a Large Animal Model of Traumatic Brain Injury and Polytrauma

    Imam, A., Jin, G., Sillesen, M., Dekker, S. E., Bambakidis, T., Hwabejire, J. O., Jepsen, C. H., Halaweish, I. & Alam, H. B., 2015, In: Journal of Neurotrauma. 32, 5, p. 307-13

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Statins improve the resolution of established murine venous thrombosis: reductions in thrombus burden and vein wall scarring

    Kessinger, C. W., Kim, J. W., Henke, P. K., Thompson, B., McCarthy, J. R., Hara, T., Sillesen, M., Margey, R. J. P., Libby, P., Weissleder, R., Lin, C. P. & Jaffer, F. A., 2015, In: P L o S One. 10, 2, p. e0116621

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2014
  36. Published

    Coagulation changes following traumatic brain injury and shock

    Sillesen, M., Dec 2014, In: Danish Medical Bulletin (Online). 61, 12, p. B4974

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Resuscitation speed affects brain injury in a large animal model of traumatic brain injury and shock

    Sillesen, M., Jin, G., Johansson, P. I. & Alam, H. B., 14 Aug 2014, In: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 22, 1, p. 46

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published
  39. Published

    Histone deacetylase inhibitor treatment attenuates coagulation imbalance in a lethal murine model of sepsis

    Zhao, T., Li, Y., Liu, B., Wu, E., Sillesen, M., Velmahos, G. C., Halaweish, I. & Alam, H. B., Aug 2014, In: Surgery. 156, 2, p. 214-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Effect of pharmacologic resuscitation on the brain gene expression profiles in a swine model of traumatic brain injury and hemorrhage

    Dekker, S. E., Bambakidis, T., Sillesen, M., Liu, B., Johnson, C. N., Jin, G., Li, Y. & Alam, H. B., 21 Jul 2014, In: The journal of trauma and acute care surgery. 77, 6, p. 906-912

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Treatment with a histone deacetylase inhibitor, valproic acid, is associated with increased platelet activation in a large animal model of traumatic brain injury and hemorrhagic shock

    Dekker, S. E., Sillesen, M., Bambakidis, T., Andjelkovic, A. V., Jin, G., Liu, B., Boer, C., Johansson, P. I., Linzel, D., Halaweish, I. & Alam, H. B., Jul 2014, In: The Journal of surgical research. 190, 1, p. 312-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Normal saline influences coagulation and endothelial function after traumatic brain injury and hemorrhagic shock in pigs

    Dekker, S. E., Sillesen, M., Bambakidis, T., Jin, G., Liu, B., Boer, C., Johansson, P. I., Halaweish, I., Maxwell, J. & Alam, H. B., 19 Jun 2014, In: Surgery. 156, 3, p. 556-563

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Fresh frozen plasma resuscitation attenuates platelet dysfunction compared with normal saline in a large animal model of multisystem trauma

    Sillesen, M., Johansson, P. I., Rasmussen, L. S., Jin, G., Jepsen, C. H., Imam, A., Hwabejire, J. O., Deperalta, D., Duggan, M., Demoya, M., Velmahos, G. C. & Alam, H. B., Apr 2014, In: The journal of trauma and acute care surgery. 76, 4, p. 998-1007 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Assessment of coagulopathy, endothelial injury, and inflammation after traumatic brain injury and hemorrhage in a porcine model

    Sillesen, M., Rasmussen, L. S., Jin, G., Jepsen, C. H., Imam, A., Hwabejire, J. O., Halaweish, I., Demoya, M., Velmahos, G., Johansson, P. I. & Alam, H. B., Jan 2014, In: The journal of trauma and acute care surgery. 76, 1, p. 12-20 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Coagulation Changes Following Traumatic Brain Injury and Shock (PhD thesis)

    Sillesen, M., 2014, 40 p.

    Research output: Book/ReportPh.D. thesis

  46. 2013
  47. Published

    Differential effects of fresh frozen plasma and normal saline on secondary brain damage in a large animal model of polytrauma, hemorrhage and traumatic brain injury

    Hwabejire, J. O., Imam, A. M., Jin, G., Liu, B., Li, Y., Sillesen, M., Jepsen, C. H., Lu, J., Demoya, M. A. & Alam, H. B., Dec 2013, In: The journal of trauma and acute care surgery. 75, 6, p. 968-75 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Early treatment with lyophilized plasma protects the brain in a large animal model of combined traumatic brain injury and hemorrhagic shock

    Imam, A. M., Jin, G., Sillesen, M., Duggan, M., Jepsen, C. H., Hwabejire, J. O., Lu, J., Liu, B., Demoya, M. A., Velmahos, G. C. & Alam, H. B., Dec 2013, In: The journal of trauma and acute care surgery. 75, 6, p. 976-83 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Fresh-frozen plasma resuscitation after traumatic brain injury and shock attenuates extracellular nucleosome levels and deoxyribonuclease 1 depletion

    Sillesen, M., Jin, G., Oklu, R., Albadawi, H., Imam, A. M., Jepsen, C. H., Hwabejire, J. O., Ostrowski, S. R., Johansson, P. I., Rasmussen, L. S. & Alam, H. B., Aug 2013, In: Surgery. 154, 2, p. 197-205 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Pharmacologic modulation of cerebral metabolic derangement and excitotoxicity in a porcine model of traumatic brain injury and hemorrhagic shock

    Hwabejire, J. O., Jin, G., Imam, A. M., Duggan, M., Sillesen, M., Deperalta, D., Jepsen, C. H., Lu, J., Li, Y., deMoya, M. A. & Alam, H. B., Aug 2013, In: Surgery. 154, 2, p. 234-43 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Synergistic effects of fresh frozen plasma and valproic acid treatment in a combined model of traumatic brain injury and hemorrhagic shock

    Imam, A. M., Jin, G., Duggan, M., Sillesen, M., Hwabejire, J. O., Jepsen, C. H., DePeralta, D., Liu, B., Lu, J., deMoya, M. A., Socrate, S. & Alam, H. B., Aug 2013, In: Surgery. 154, 2, p. 388-96 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Platelet activation and dysfunction in a large-animal model of traumatic brain injury and hemorrhage

    Sillesen, M., Johansson, P. I., Rasmussen, L. S., Jin, G., Jepsen, C. H., Imam, A. M., Hwabejire, J., Lu, J., Duggan, M., Velmahos, G., deMoya, M. & Alam, H. B., May 2013, In: The journal of trauma and acute care surgery. 74, 5, p. 1252-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 2012
  54. Published

    Pharmacologic resuscitation for hemorrhagic shock combined with traumatic brain injury

    Jin, G., Duggan, M., Imam, A., Demoya, M. A., Sillesen, M., Hwabejire, J., Jepsen, C. H., Liu, B., Mejaddam, A. Y., Lu, J., Smith, W. M., Velmahos, G. C., Socrate, S. & Alam, H. B., Dec 2012, In: The journal of trauma and acute care surgery. 73, 6, p. 1461-70 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Detection of extracellular genomic DNA scaffold in human thrombus: implications for the use of deoxyribonuclease enzymes in thrombolysis

    Oklu, R., Albadawi, H., Watkins, M. T., Monestier, M., Sillesen, M. & Wicky, S., May 2012, In: Journal of vascular and interventional radiology : JVIR. 23, 5, p. 712-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. 2011
  57. Published

    Pregnancy with prosthetic heart valves - 30 years' nationwide experience in Denmark

    Sillesen, M., Hjortdal, V. E., Vejlstrup, N. & Sørensen, K. E., 2011, In: European Journal of Cardio-thoracic Surgery. 40, 2, p. 448-54 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. 2008
  59. Published
  60. 2006
  61. Published

    Telemedicinsk elektrokardiogramtransmission i den præhospitale fase hos patienter, der er under mistanke for at have akut myokardieinfarkt

    Sillesen, M., Ripa, M. S., Strange, S., Nielsen, S. L., Jørgensen, E., Lippert, F. K. & Clemmensen, P. M., 13 Mar 2006, In: Ugeskrift for Laeger. 168, 11, p. 1133-1136 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Telemedicinsk elektrokardiogramtransmission i den præhospitale fase hos patienter, der er under mistanke for at have en akut myokardieinfarkt

    Sillesen, M., Ripa, M. S., Strange, S., Loumann Nielsen, S., Jørgensen, E., Lippert, F. K. & Clemmensen, P. M., 2006, In: Ugeskrift for Laeger. 168, 11, p. 1133-1136 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 29757