Personal profile
Expertises
Type 1 diabetes, Innate immunology, Virus, Molecular biology, Cell biology, Intestinal permeability, Lipids, Pancreas stereology, Laboratory animal science
Main research areas
Understanding the pathogenesis of type 1 diabetes, including how environmental factors like gluten and virus contribute to the disease. Special interests include:
-prenatal nutrition and fetal programming
-the innate antiviral immunity
-intestinal permeability
-morphological changes of the intestine and pancreas
-association between celiac disease and type 1 diabetes
-lipids
Current research
Unraveling how increased intestinal permeability is involved in type 1 diabetes.
Lipidomic profiling of body fluids, aiming at identifying defects and biomarkers specific for type 1 diabetes.
Investigating the involvement of enterovirus and dysregulation of the innate antiviral immune system in type 1 diabetes.
Potential conflicts of interest
None.
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Research output
-
Cathepsin S is elevated in pancreatic islets and plasma in new-onset type 1 diabetes and positively associates with systemic inflammatory cytokines
Kaur, S., Demir, L. Ü., Frørup, C., Madsen, J. O. B., Krogvold, L., Gerling, I. C., Dahl-Jørgensen, K., Haupt-Jorgensen, M., Pociot, F., Størling, J., Johannesen, J. & Fløyel, T., 2025, In: Endocrine Abstracts. 110, P311.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
-
Dysregulation of innate antiviral immune pathways as an explanation of enterovirus-induced type 1 diabetes
Høj Jensen, M., Kaur, S., Haupt-Jorgensen, M., Pociot, F. & Fløyel, T., 2025, p. 52.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
-
Evaluation of the pharmacological cathepsin S inhibitor LY3000328 on autoimmune diabetes in mice
Frørup, C., Svane, C. A. S., Jensen, M. H., Holm, L. J., Pedersen, K., Mønsted, M. Ø., Buschard, K. S., Størling, J., Pociot, F., Haupt-Jorgensen, M. & Fløyel, T., Dec 2025, In: Biomedicine & Pharmacotherapy. 193, 118744.Research output: Contribution to journal › Journal article › Research › peer-review
-
Genetic and transcriptional dysregulation of innate antiviral immune pathways in type 1 diabetes
Mønsted, M. Ø., Pedersen, K., Jensen, M. H., Kaur, S., Sustacha, S. C., Holm, L. J., Buschard, K., Pociot, F. & Haupt-Jorgensen, M., Dec 2025, In: Immunology Letters. 276, 107060.Research output: Contribution to journal › Journal article › Research › peer-review
-
Preventing the onset of diabetes with precision delivery of mesenchymal stem cells to the pancreas in a preclinical model
Yarani, R., Primavera, R., Chetty, S., Wang, J., Kaur, S., Haupt-Jorgensen, M., Pociot, F. & Thakor, A. S., Dec 2025, In: Stem Cell Research & Therapy. 16, 1, p. 687 687.Research output: Contribution to journal › Journal article › Research › peer-review