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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2020
  2. E-pub ahead of print

    SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycaemic Control in Newly Diagnosed Patients

    Fløyel, T., Meyerovich, K., Prause, M. C., Kaur, S., Frørup, C., Mortensen, H. B., Nielsen, L. B., Pociot, F., Cardozo, A. K. & Størling, J., 17 Nov 2020, In : Diabetes.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2019
  4. Published
  5. 2018
  6. Published

    Influence of Disease Duration on Circulating Levels of miRNAs in Children and Adolescents with New Onset Type 1 Diabetes

    Samandari, N., Mirza, A. H., Kaur, S., Hougaard, P., Nielsen, L. B., Fredheim, S., Mortensen, H. B. & Pociot, F., 21 Nov 2018, In : Non-Coding RNA. 4, 4, p. 35 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The type 1 diabetes candidate gene Src kinase associated phosphoprotein 2 (SKAP2) controls beta-cell sensitivity to pro-inflammatory cytokines

    Størling, J., Meyerovich, K., Fløyel, T., Mortensen, H. B., Nielsen, L. B., Eizirik, D. L., Cardozo, A. K. & Pociot, F., 1 Oct 2018, In : Diabetologia. 61, Suppl 1, p. S200-S201 1 p., 403.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  8. 2017
  9. Published

    Increased mortality in a Danish cohort of young people with Type 1 diabetes mellitus followed for 24 years

    Sandahl, K., Nielsen, L. B., Svensson, J., Johannesen, J., Pociot, F., Mortensen, H. B., Hougaard, P., Broe, R., Rasmussen, M. L., Grauslund, J., Peto, T. & Olsen, B. S., Mar 2017, In : Diabetic Medicine Online. 34, 3, p. 380-386 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Circulating microRNA levels predict residual beta cell function and glycaemic control in children with type 1 diabetes mellitus

    Samandari, N., Mirza, A. H., Nielsen, L. B., Kaur, S., Hougaard, P., Fredheim, S., Mortensen, H. B. & Pociot, F., Feb 2017, In : Diabetologia. 60, 2, p. 354-363 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2016
  12. Published

    Effects of the genome on immune regulation in type 1 diabetes

    Pociot, F., Kaur, S. & Nielsen, L. B., Jul 2016, In : Pediatric Diabetes. 17 Suppl 22, p. 37-42 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes

    Fukaya, M., Brorsson, C. A., Meyerovich, K., Catrysse, L., Delaroche, D., Vanzela, E. C., Ortis, F., Beyaert, R., Nielsen, L. B., Andersen, M. L., Mortensen, H. B., Pociot, F., van Loo, G., Størling, J. & Cardozo, A. K., 2016, In : Molecular Endocrinology. 30, 1, p. 48-61 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published
  16. 2015
  17. Published

    Nationwide reduction in the frequency of severe hypoglycemia by half

    Fredheim, S., Johansen, A., Thorsen, S. U., Kremke, B., Nielsen, L. B., Olsen, B. S., Lyngsøe, L., Sildorf, S. M., Pipper, C., Mortensen, H. B., Johannesen, J., Svensson, J. & The Danish Society for Diabetes in Childhood and Adolescence, 21 Dec 2015, In : Acta Diabetologica. 52, 3, p. 591-599 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published
  19. Published

    The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes

    Fredheim, S., Andersen, M. L. M., Pörksen, S., Nielsen, L. B., Pipper, C., Hansen, L., Holst, J. J., Thomsen, J., Johannesen, J., Mortensen, H. B. & Svensson, J., 2015, In : Diabetologia. 58, 4, p. 828-34 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2014
  21. Published

    Partial remission definition: validation based on the insulin dose-adjusted HbA1c (IDAA1C) in 129 Danish children with new-onset type 1 diabetes

    Andersen, M. L. M., Hougaard, P., Pörksen, S., Nielsen, L. B., Fredheim, S., Svensson, J., Thomsen, J., Vikre-Jørgensen, J., Hertel, T., Petersen, J. S., Hansen, L. & Mortensen, H. B., Nov 2014, In : Pediatric Diabetes. 15, 7, p. 469-76 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Disease progression among 446 children with newly diagnosed type 1 diabetes located in Scandinavia, Europe, and North America during the last 27 yr

    Andersen, M. L. M., Nielsen, L. B., Svensson, J., Pörksen, S., Hougaard, P., Craig, B., Carla, G., Becker, D., Petersen, J. S., Hansen, L. & Mortensen, H. B., Aug 2014, In : Pediatric Diabetes. 15, 5, p. 345-354 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients

    Fløyel, T., Brorsson, C., Nielsen, L. B., Miani, M., Bang-Berthelsen, C. H., Friedrichsen, M., Overgaard, A. J., Berchtold, L. A., Wiberg, A., Poulsen, P., Hansen, L., Rosinger, S., Boehm, B. O., Ram, R., Nguyen, Q., Mehta, M., Morahan, G., Concannon, P., Bergholdt, R., Nielsen, J. H., Reinheckel, T., von Herrath, M., Vaag, A., Eizirik, D. L., Mortensen, H. B., Størling, J. & Pociot, F., 15 Jul 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 28, p. 10305-10 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Glycaemic threshold for diabetes-specific retinopathy among individuals from Saudi Arabia, Algeria and Portugal

    Almdal, T. P., Handlos, L. N., Valerius, M., Juul, E., Nielsen, K. E., Vistisen, D., Nielsen, L. B., Sheikh, A., Belhadj, M., Nadir, D., Zinai, S., Raposo, J., Lund-Andersen, H. & Witte, D. R., Mar 2014, In : Diabetes Research and Clinical Practice. 103, 3, p. e44-6

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2013
  26. Published

    Complex Multi-Block Analysis Identifies New Immunologic and Genetic Disease Progression Patterns Associated with the Residual β-Cell Function 1 Year after Diagnosis of Type 1 Diabetes

    Andersen, M. L. M., Rasmussen, M. A., Pörksen, S., Svensson, J., Vikre-Jørgensen, J., Thomsen, J., Hertel, N. T., Johannesen, J., Pociot, F., Petersen, J. S., Hansen, L., Mortensen, H. B. & Nielsen, L. B., 2013, In : P L o S One. 8, 6, p. e64632

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2012
  28. Published

    Association between autoantibodies to the Arginine variant of the Zinc transporter 8 (ZnT8) and stimulated C-peptide levels in Danish children and adolescents with newly diagnosed type 1 diabetes

    Andersen, M. L. M., Vaziri-Sani, F., Delli, A., Pörksen, S., Jacobssen, E., Thomsen, J., Svensson, J., Steen Petersen, J., Hansen, L., Lernmark, A., Mortensen, H. B. & Nielsen, L. B., 2012, In : Pediatric Diabetes. 13, 6, p. 454-62 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published
  30. Published

    Proinsulin, GLP-1, and glucagon are associated with partial remission in children and adolescents with newly diagnosed type 1 diabetes

    Kaas, A., Andersen, M. L. M., Fredheim, S., Hougaard, P., Buschard, K., Petersen, J. S., de Beaufort, C., Robertson, K. J., Hansen, L., Mortensen, H. B., Nielsen, L. B. & Hvidoere Study Group on childhood diabetes, 2012, In : Pediatric Diabetes. 13, 1, p. 51-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2011
  32. Published

    Relationship between ZnT8Ab, the SLC30A8 gene and disease progression in children with newly diagnosed type 1 diabetes

    Nielsen, L. B., Vaziri-Sani, F., Pörksen, S., Andersen, M. L. M., Svensson, J., Bergholdt, R., Pociot, F., Hougaard, P., de Beaufort, C., Castaño, L., Mortensen, H. B., Lernmark, A., Hansen, L. & Hvidoere Study Group on Childhood Diabetes, Dec 2011, In : Autoimmunity Highlights. 44, 8, p. 616-23 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Intrafamilial Variability of Early-Onset Diabetes due to an INS Mutation

    Fredheim, S., Svensson, J., Pörksen, S., Hansen, L., Hansen, T., Pedersen, O., Mortensen, H. B., F, B. & Nielsen, L. B., 2011, In : Case Reports in Genetics. 2011, 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    The PTPN22 C1858T gene variant is associated with proinsulin in new-onset type 1 diabetes

    Nielsen, L. B., Pörksen, S., Andersen, M. L. M., Fredheim, S., Svensson, J., Hougaard, P., Vanelli, M., Åman, J., Mortensen, H. B., Hansen, L. & Hvidoere Study Group on Childhood Diabetes, 2011, In : B M C Medical Genetics. 12, p. 41

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2010
  36. Published

    Analyses of the rate of decline in stimulated c-peptide 12 months after diagnosis in children with newly diag-nosed type 1 diabetes. results from the Hvidoere study group on childhood diabetes

    Andersen, M. L. M., Pörksen, S., Nielsen, L. B., Svensson, J., Johannesen, J., Hougaard, P., Jørgensen, J. V., Thomsen, J., Hertel, N. T., Petersen, J. S., Karlsen, A. E., Hansen, L. & Mortensen, H. B., 2010, In : Pediatric Diabetes.

    Research output: Contribution to journalConference articleResearchpeer-review

  37. Published
  38. Published

    Association of type 2 diabetes genes WFS and HHEX-IDE with disease progression in children with new onset type 1 diabetes

    Nielsen, L. B., Andersen, M. L. M., Svensson, J., Pörksen, S., Hougaard, P., Swift, P., Hoey, H., Mortensen, H. B. & Hansen, L., 2010, In : Diabetologia. 53, p. 277 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  39. Published

    Mutation in APOA1 predicts increased risk of ischaemic heart disease and mortality without low HDL cholesterol

    Haase, C. L., Frikke-Schmidt, R., Nordestgaard, B. G., Kateifides, A. K., Kardassis, D., Nielsen, L. B., Johnsen, A. H., Grande, P., Zannis, V. I. & Tybjærg-Hansen, A., 2010, In : Amyloid. 17, p. 129 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  40. Published

    Prediction of remission after 6 months and residual beta cell function 12 months after diagnosis in Danish children using multivariate statistical methods

    Andersen, M. L. M., Rasmussen, M. A., Pörksen, S., Nielsen, L. B., Svensson, J., Jorgensen, J. V., Thomsen, J., Hertel, N., Petersen, J. S., Karlsen, A. E., Hansen, L. & Mortensen, H. B., 2010, In : Diabetologia. 53, p. S189-S189

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  41. Published

    Proinsulin Associates with Glycaemic Control and Insulin Dose Independent of Stimulated C-Peptide in Children with New Onset Type 1 Diabetes. Results from the Hvidoere Study Group

    Andersen, M. L. M., Nielsen, L. B., Kaas, A., Svensson, J., Pörksen, S., Hougaard, P., Schonle, E., Swift, P., De Baufort, C., Chiarelli, F., Hansen, L. & Mortensen, H. B., 2010, In : Diabetes. 59, p. A453-A453

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  42. Published

    The PTPN22 C1858T Gene Variant in Relation to Residual Beta-Cell Function in New-Onset Type 1 Diabetes: Association with Proinsulin but Not with C-Peptide

    Nielsen, L. B., Pörksen, S., Andersen, M. L. M., Svensson, J., Hougaard, P., Vanelli, M., Aaman, J., Mortensen, H. B. & Hansen, L., 2010, In : Diabetes. 59, p. A329-A329

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  43. 2007
  44. Published

    Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes

    Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, C., Jansen-Olesen, I., Chiarelli, F., Holst, J. J., Hougaard, P., Pörksen, S., Holl, R., de Beaufort, C., Gammeltoft, S., Rorsman, P., Mortensen, H. B., Hansen, L. & Hvidøre Study Group, 2007, In : European Journal of Endocrinology. 156, 6, p. 663-71 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 32277878