Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

Blokland, G. A. M., Grove, J., Chen, C. Y., Cotsapas, C., Tobet, S., Handa, R., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M. & 35 others, Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Hansen, M., Hansen, T., Meier, S., Olsen, L., Bækvad-Hansen, M., Hansen, T. F., Thompson, W., Weinsheimer, S. M., Nordentoft, M., Werge, T., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium & iPSYCH, 2022, In: Biological Psychiatry. 91, 1, p. 102-117 16 p.

Research output: Contribution to journal › Journal article › peer-review

Can Animal Models of Copy Number Variants That Predispose to Schizophrenia Elucidate Underlying Biology?

Forsingdal, A., Jørgensen, T. N., Olsen, L., Werge, T., Didriksen, M. & Nielsen, J., 1 Jan 2019, In: Biological Psychiatry. 85, 1, p. 13-24 12 p.

Research output: Contribution to journal › Review › peer-review

Individuals with 22q11.2 deletion syndrome show intact prediction but reduced adaptation in responses to repeated sounds: Evidence from Bayesian mapping

Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Olsen, L., Didriksen, M., Baaré, W. F. C., Werge, T. M., Garrido, M. I. & Siebner, H. R., 2019, In: NeuroImage. Clinical. 22, p. 1-10 101721.

Research output: Contribution to journal › Journal article › peer-review

Age at first birth in women is genetically associated with increased risk of schizophrenia

Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Hansen, T. F., Werge, T. M., Olsen, L., Rasmussen, H. B. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 5 Jul 2018, In: Scientific Reports. 8, 1, p. 10168

Research output: Contribution to journal › Journal article › peer-review

Prevalence of rearrangements in the 22q11.2 region and population-based risk of neuropsychiatric and developmental disorders in a Danish population: a case-cohort study

Olsen, L., Sparsø, T., Weinsheimer, S. M., Dos Santos, M. B. Q., Mazin, W., Rosengren, A., Sanchez, X. C., Hoeffding, L. K., Schmock, H., Baekvad-Hansen, M., Bybjerg-Grauholm, J., Daly, M. J., Neale, B. M., Pedersen, M. G., Agerbo, E., Mors, O., Børglum, A., Nordentoft, M., Hougaard, D. M., Mortensen, P. B. & 4 others, Geschwind, D. H., Pedersen, C., Thompson, W. K. & Werge, T., Jul 2018, In: The Lancet. Psychiatry. 5, 7, p. 573-580 8 p.

Research output: Contribution to journal › Journal article › peer-review

A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework

LeBlanc, M., Zuber, V., Thompson, W. K., Andreassen, O. A., Frigessi, A., Andreassen, B. K., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M. & 31 others, Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Cahn, W., Cai, G., Cairns, M. J., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Hansen, M., Hansen, T., Meier, S., Olsen, L., Rasmussen, H. B., Werge, T. & Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, 25 Jun 2018, In: BMC Genomics. 19, 1, 494.

Research output: Contribution to journal › Journal article › peer-review

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Ruderfer, D. M., Ripke, S., McQuillin, A., Boocock, J., Stahl, E. A., Pavlides, J. M. W., Mullins, N., Charney, A. W., Ori, A. P. S., Loohuis, L. M. O., Domenici, E., Di Florio, A., Papiol, S., Kalman, J. L., Trubetskoy, V., Adolfsson, R., Agartz, I., Agerbo, E., Akil, H., Albani, D. & 33 others, Albus, M., Alda, M., Alexander, M., Alliey-Rodriguez, N., Als, T. D., Amin, F., Anjorin, A., Arranz, M. J., Awasthi, S., Bacanu, S. A., Badner, J. A., Baekvad-Hansen, M., Bakker, S., Band, G., Barchas, J. D., Barroso, I., Bass, N., Bauer, M., Baune, B. T., Begemann, M., Bellenguez, C., Belliveau, R. A., Hansen, M., Hansen, T., Meier, S., Nordentoft, M., Olsen, L., Pers, T. H., Rasmussen, H. B., Werge, T., Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, Psychosis Endophenotypes International Consortium & Wellcome Trust Case-Control Consortium, 14 Jun 2018, In: Cell. 173, 7, p. 1705-1715.e16

Research output: Contribution to journal › Journal article › peer-review

Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood

Ni, G., Moser, G., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A., Begemann, M. & 33 others, Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Hansen, M., Hansen, T., Meier, S., Olsen, L., Rasmussen, H. B., Werge, T., Wellcome Trust Case-Control Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium & Psychosis Endophenotypes International Consortium, 7 Jun 2018, In: American Journal of Human Genetics. 102, 6, p. 1185-1194 10 p.

Research output: Contribution to journal › Journal article › peer-review

22q11.2 Deletion Syndrome Is Associated With Impaired Auditory Steady-State Gamma Response

Larsen, K. M., Pellegrino, G., Birknow, M. R., Kjær, T. N., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, T., Mørup, M. & Siebner, H. R., Feb 2018, In: Schizophrenia Bulletin. 44, 2, p. 388-397

Research output: Contribution to journal › Journal article › peer-review

Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome

Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Hulme, O., Vangkilde, A., Schmock, H., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, T., Siebner, H. R. & Garrido, M. I., 30 Jan 2018, In: Schizophrenia Research.

Research output: Contribution to journal › Journal article › peer-review

Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome

Starnawska, A., Hansen, C. S., Sparsø, T., Mazin, W., Olsen, L., Bertalan, M., Demur, A. A. B., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Mortensen, P. B., Pedersen, C. B., Nyegaard, M., Werge, T. & Weinsheimer, S., 29 Aug 2017, In: Translational psychiatry. 7, 8, p. e1221

Research output: Contribution to journal › Journal article › peer-review

The impact of lifestyle risk factors on the rate of infection after surgery for a fracture of the ankle

Olsen, L. L., Møller, A. M., Brorson, S., Hasselager, R. B. & Sort, R., Feb 2017, In: The bone & joint journal. 99-B, 2, p. 225-230 6 p.

Research output: Contribution to journal › Journal article › peer-review

Risk of Psychiatric Disorders Among Individuals With the 22q11.2 Deletion or Duplication: A Danish Nationwide, Register-Based Study

Hoeffding, L. K., Trabjerg, B. B., Olsen, L., Mazin, W., Sparsø, T., Vangkilde, A., Mortensen, P. B., Pedersen, C. B. & Werge, T., 18 Jan 2017, In: JAMA Psychiatry.

Research output: Contribution to journal › Journal article › peer-review

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Hansen, T. F., Werge, T. M., Olsen, L., Bertalan, M. & CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium, Jan 2017, In: Nature Genetics. 49, 1, p. 27-35 9 p.

Research output: Contribution to journal › Journal article › peer-review

Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment

Le Hellard, S., Wang, Y., Witoelar, A., Zuber, V., Bettella, F., Hugdahl, K., Espeseth, T., Steen, V. M., Melle, I., Desikan, R., Schork, A. J., Thompson, W. K., Dale, A. M., Djurovic, S., Andreassen, O. A. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 2017, In: Schizophrenia Bulletin. 43, 3, p. 654-664

Research output: Contribution to journal › Journal article › peer-review

Associations between social cognition, skills, and function and subclinical negative and positive symptoms in 22q11.2 deletion syndrome

Vangkilde, A., Jepsen, J. R. M., Schmock, H., Olesen, C., Arnarsdóttir, S., Baaré, W. F. C., Plessen, K. J., Didriksen, M., Siebner, H. R., Werge, T. & Olsen, L., Nov 2016, In: Journal of Neurodevelopmental Disorders. 8, 1, 13 p., 42.

Research output: Contribution to journal › Journal article › peer-review

Høj risiko for skizofreni-spektrum sygdomme i 22q11.2 deletionssyndrom

Olsen, L., Nov 2016, In: Best Practice - Psykiatri/Neurologi. 35, p. 32-33 2 p.

Research output: Contribution to journal › Journal article › peer-review

No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study

Johnson, E. C., Bjelland, D. W., Howrigan, D. P., Abdellaoui, A., Breen, G., Borglum, A., Cichon, S., Degenhardt, F., Forstner, A. J., Frank, J., Genovese, G., Heilmann-Heimbach, S., Herms, S., Hoffman, P., Maier, W., Mattheisen, M., Morris, D., Mowry, B., Müller-Mhysok, B., Neale, B. & 14 others, Nenadic, I., Nöthen, M. M., O'Dushlaine, C., Rietschel, M., Ruderfer, D. M., Rujescu, D., Schulze, T. G., Simonson, M. A., Stahl, E., Strohmaier, J., Witt, S. H., Sullivan, P. F., Keller, M. C. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, Oct 2016, In: P L o S Genetics. 12, 10, p. e1006343

Research output: Contribution to journal › Journal article › peer-review

Genome-Wide Association Studies Suggest Limited Immune Gene Enrichment in Schizophrenia Compared to 5 Autoimmune Diseases

Pouget, J. G., Gonçalves, V. F., Spain, S. L., Finucane, H. K., Raychaudhuri, S., Kennedy, J. L., Knight, J. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, Sep 2016, In: Schizophrenia Bulletin. 42, 5, p. 1176-84 9 p.

Research output: Contribution to journal › Journal article › peer-review

Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women

Mehta, D., Tropf, F. C., Gratten, J., Bakshi, A., Zhu, Z., Bacanu, S-A., Hemani, G., Magnusson, P. K. E., Barban, N., Esko, T., Metspalu, A., Snieder, H., Mowry, B. J., Kendler, K. S., Yang, J., Visscher, P. M., McGrath, J. J., Mills, M. C., Wray, N. R., Lee, S. H. & 28 others, Andreassen, O. A., Bramon, E., Bruggeman, R., Buxbaum, J. D., Cairns, M. J., Cantor, R. M., Cloninger, C. R., Cohen, D., Crespo-Facorro, B., Darvasi, A., DeLisi, L. E., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Escott-Price, V., Freimer, N. B., Georgieva, L., de Haan, L., Henskens, F. A., Joa, I., Julià, A., Khrunin, A., Lerer, B., Limborska, S., Loughland, C. M., Macek, M. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, LifeLines Cohort Study, and TwinsUK, 1 May 2016, In: JAMA Psychiatry. 73, 5, p. 497-505 9 p.

Research output: Contribution to journal › Journal article › peer-review

Schizophrenia Spectrum Disorders in a Danish 22q11.2 Deletion Syndrome Cohort Compared to the Total Danish Population-A Nationwide Register Study

Vangkilde, A., Olsen, L., Hoeffding, L. K., Pedersen, C. B., Mortensen, P. B., Werge, T. & Trabjerg, B., May 2016, In: Schizophrenia Bulletin. 42, 3, p. 824-831

Research output: Contribution to journal › Journal article › peer-review

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

Franke, B., Stein, J. L., Ripke, S., Anttila, V., Hibar, D. P., van Hulzen, K. J. E., Arias-Vasquez, A., Smoller, J. W., Nichols, T. E., Neale, M. C., McIntosh, A. M., Lee, P., McMahon, F. J., Meyer-Lindenberg, A., Mattheisen, M., Andreassen, O. A., Gruber, O., Sachdev, P. S., Roiz-Santiañez, R., Saykin, A. J. & 15 others, Ehrlich, S., Mather, K. A., Turner, J. A., Schwarz, E., Thalamuthu, A., Yao, Y., Ho, Y. Y. W., Martin, N. G., Wright, M. J., O'Donovan, M. C., Thompson, P. M., Neale, B. M., Medland, S. E., Sullivan, P. F. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, Mar 2016, In: Nature Neuroscience. 19, 3, p. 420-31 12 p.

Research output: Contribution to journal › Journal article › peer-review

Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

Holland, D., Wang, Y., Thompson, W. K., Schork, A., Chen, C-H., Lo, M-T., Witoelar, A., Werge, T., O'Donovan, M., Andreassen, O. A., Dale, A. M. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 16 Feb 2016, In: Frontiers in genetics. 7, p. 15

Research output: Contribution to journal › Journal article › peer-review

Schizophrenia risk from complex variation of complement component 4

Sekar, A., Bialas, A. R., de Rivera, H., Davis, A., Hammond, T. R., Kamitaki, N., Tooley, K., Presumey, J., Baum, M., Van Doren, V., Genovese, G., Rose, S. A., Handsaker, R. E., Daly, M. J., Carroll, M. C., Stevens, B., McCarroll, S. A. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, Feb 2016, In: Nature. 530, 7589, p. 177-183

Research output: Contribution to journal › Journal article › peer-review

Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes

Pers, T. H., Timshel, P., Ripke, S., Lent, S., Sullivan, P. F., O'Donovan, M. C., Franke, L., Hirschhorn, J. N., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Hansen, T. F., Werge, T. M. & Olsen, L., 10 Jan 2016, In: Human Molecular Genetics. 25, 6, p. 1247-1254

Research output: Contribution to journal › Journal article › peer-review

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

Bigdeli, T. B., Ripke, S., Bacanu, S-A., Lee, S. H., Wray, N. R., Gejman, P. V., Rietschel, M., Cichon, S., St Clair, D., Corvin, A., Kirov, G., McQuillin, A., Gurling, H., Rujescu, D., Andreassen, O. A., Werge, T., Blackwood, D. H. R., Pato, C. N., Pato, M. T., Malhotra, A. K. & 4 others, O'Donovan, M. C., Kendler, K. S., Fanous, A. H. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 11 Dec 2015, In: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Research output: Contribution to journal › Journal article › peer-review

An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies

Thompson, W. K., Wang, Y., Schork, A. J., Witoelar, A., Zuber, V., Xu, S., Werge, T., Holland, D., Andreassen, O. A., Dale, A. M. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, Dec 2015, In: P L o S Genetics. 11, 12, p. e1005717

Research output: Contribution to journal › Journal article › peer-review

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

Loh, P-R., Bhatia, G., Gusev, A., Finucane, H. K., Bulik-Sullivan, B. K., Pollack, S. J., de Candia, T. R., Lee, S. H., Wray, N. R., Kendler, K. S., O'Donovan, M. C., Neale, B. M., Patterson, N., Price, A. L. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, Dec 2015, In: Nature Genetics. 47, 12, p. 1385-92 8 p.

Research output: Contribution to journal › Journal article › peer-review

An atlas of genetic correlations across human diseases and traits

Bulik-Sullivan, B., Finucane, H. K., Anttila, V., Gusev, A., Day, F. R., Loh, P-R., Duncan, L., Perry, J. R. B., Patterson, N., Robinson, E. B., Daly, M. J., Price, A. L., Neale, B. M. & ReproGen Consortium, Nov 2015, In: Nature Genetics. 47, 11, p. 1236-41 6 p.

Research output: Contribution to journal › Journal article › peer-review

Genetic Markers of Human Evolution Are Enriched in Schizophrenia

Srinivasan, S., Bettella, F., Mattingsdal, M., Wang, Y., Witoelar, A., Schork, A. J., Thompson, W. K., Zuber, V., Winsvold, B. S., Zwart, J-A., Collier, D. A., Desikan, R. S., Melle, I., Werge, T., Dale, A. M., Djurovic, S., Andreassen, O. A. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium, 21 Oct 2015, In: Biological Psychiatry.

Research output: Contribution to journal › Journal article › peer-review

Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case–control sample of schizophrenia

Ingason, A., Giegling, I., Harmann, AM., Genius, J., Konte, B., Fried, M., of the Psychaitric Genomics Consortium, S. W. G., Ripke, S., Sullivan, P. F., St Clair, D., Collier, D., O'Donovan, M. C., Mirnics, K., Rujescu, D., Hansen, T. F., Werge, T. M. & Olsen, L., Oct 2015, In: Translational Psychiatry. 5, 10, p. e656 1 p.

Research output: Contribution to journal › Journal article › peer-review

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

Lee, S. H., Byrne, E. M., Hultman, C. M., Kähler, A., Vinkhuyzen, A. A., Ripke, S., Andreassen, O. A., Frisell, T., Gusev, A., Hu, X., Karlsson, R., Mantzioris, V. X., McGrath, J. J., Mehta, D., Stahl, E. A., Zhao, Q., Kendler, K. S., Sullivan, P. F., Price, A. L., O'Donovan, M. & 31 others, Okada, Y., Mowry, B. J., Raychaudhuri, S., Wray, N. R., Byerley, W., Cahn, W., Cantor, R. M., Cichon, S., Cormican, P., Curtis, D., Djurovic, S., Escott-Price, V., Gejman, P. V., Georgieva, L., Giegling, I., Hansen, T. F., Ingason, A., Kim, Y., Konte, B., Lee, P. H., McIntosh, A., McQuillin, A., Morris, D. W., Nöthen, M. M., O'Dushlaine, C., Olincy, A., Olsen, L., Pato, C. N., Rasmussen, H. B., Werge, T. & Schizophrenia Working Group of the Psychiatric Genomics Consortium and Rheumatoid Arthritis Consortium International, Oct 2015, In: International Journal of Epidemiology. 44, 5, p. 1706-1721

Research output: Contribution to journal › Journal article › peer-review

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

Bulik-Sullivan, B. K., Loh, P-R., Finucane, H. K., Ripke, S., Yang, J., Patterson, N., Daly, M. J., Price, A. L., Neale, B. M. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, Mar 2015, In: Nature Genetics. 47, 3, p. 291-5 5 p.

Research output: Contribution to journal › Journal article › peer-review

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

The Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium, 19 Jan 2015, In: Nature Neuroscience.

Research output: Contribution to journal › Journal article › peer-review

Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci

Andreassen, O. A., Harbo, H. F., Wang, Y., Thompson, W. K., Schork, A. J., Mattingsdal, M., Zuber, V., Bettella, F., Ripke, S., Kelsoe, J. R., Kendler, K. S., O'Donovan, M. C., Sklar, P., McEvoy, L. K., Desikan, R. S., Lie, B. A., Djurovic, S., Dale, A. M. & The Psychiatric Genomics Consortium (PGC) Bipolar Disorder and Schizophrenia Work Groups, 2015, In: Molecular Psychiatry. 20, 2, p. 207-214 7 p.

Research output: Contribution to journal › Journal article › peer-review

The Danish 22q11 research initiative

Schmock, H., Vangkilde, A., Larsen, K. M., Fischer, E., Birknow, M. R., Jepsen, J. R. M., Olesen, C., Skovby, F., Plessen, K. J., Mørup, M., Hulme, O., Baaré, W. F. C., Didriksen, M., Siebner, H. R., Werge, T. & Olsen, L., 2015, In: B M C Psychiatry. 15, 1, p. 220

Research output: Contribution to journal › Journal article › peer-review

Biological insights from 108 schizophrenia-associated genetic loci

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 24 Jul 2014, In: Nature. 511, 7510, p. 421-7 7 p.

Research output: Contribution to journal › Journal article › peer-review

Common variant at 16p11.2 conferring risk of psychosis

Steinberg, S., de Jong, S., Mattheisen, M., Costas, J., Demontis, D., Jamain, S., Pietiläinen, O. P. H., Lin, K., Papiol, S., Huttenlocher, J., Sigurdsson, E., Vassos, E., Giegling, I., Breuer, R., Fraser, G., Walker, N., Melle, I., Djurovic, S., Agartz, I., Tuulio-Henriksson, A. & 31 others, Suvisaari, J., Lönnqvist, J., Paunio, T., Olsen, L., Hansen, T. F., Ingason, A., Pirinen, M., Strengman, E., Hougaard, D. M., Orntoft, T., Didriksen, M., Hollegaard, M. V., Nordentoft, M., Abramova, L., Kaleda, V., Arrojo, M., Sanjuán, J., Arango, C., Etain, B., Bellivier, F., Méary, A., Schürhoff, F., Szoke, A., Ribolsi, M., Magni, V., Siracusano, A., Sperling, S., Rossner, M., Christiansen, C., Werge, T. & GROUP, 2014, In: Molecular Psychiatry. 19, p. 108–114

Research output: Contribution to journal › Journal article › peer-review

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Lee, S. H., Ripke, S., Neale, B. M., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Anney, R., Anttila, V., Arking, D. E., Asherson, P. & 31 others, Azevedo, M. H., Backlund, L., Badner, J. A., Bailey, A. J., Banaschewski, T., Barchas, J. D., Barnes, M. R., Barrett, T. B., Bass, N., Battaglia, A., Bauer, M., Bayés, M., Bellivier, F., Bergen, S. E., Berrettini, W., Betancur, C., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H. R., Bloss, C. S., Boehnke, M., Boomsma, D. I., Breen, G., Hansen, T. F., Ingason, A., Olsen, L., Rasmussen, H. B., Werge, T. & Cross-Disorder Group of the Psychiatric Genomics Consortium, 11 Aug 2013, In: Nature Genetics. p. 984-994 11 p.

Research output: Contribution to journal › Journal article › peer-review

Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC

Hamshere, M. L., Walters, J. T. R., Smith, R., Richards, A., Green, E., Grozeva, D., Jones, I., Forty, L., Jones, L. R., Gordon-Smith, K., Riley, B., O'Neill, T., Kendler, K. S., Sklar, P., Purcell, S., Kranz, J., Morris, D. J., Gill, M., Holmans, P., Craddock, N. & 4 others, Corvin, A., Owen, M. J., O'Donovan, M. C. & The Schizophrenia Psychiatric Genome-wide Association Study Consortium (PGC), Wellcome Trust Case Control Consortium+ (WTCCC+), Wellcome Trust Case Control Consortium 2 (WTCCC2), Jun 2013, In: Molecular Psychiatry. 18, 6, p. 708-712 5 p.

Research output: Contribution to journal › Journal article › peer-review

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

Cross-Disorder Group of the Psychiatric Genomics Consortium, 20 Apr 2013, In: Lancet. 381, 9875, p. 1371-9 9 p.

Research output: Contribution to journal › Journal article › peer-review

All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs. genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

Tobacco and Genetics Consortium & The Schizophrenia Psychiatric Genomics Consortium, Apr 2013, In: P L o S Genetics. 9, 4, p. e1003449

Research output: Contribution to journal › Journal article › peer-review

Enhanced maternal origin of the 22q11.2 deletion in velocardiofacial and DiGeorge syndromes

Delio, M., Guo, T., McDonald-McGinn, D. M., Zackai, E., Herman, S., Kaminetzky, M., Higgins, A. M., Coleman, K., Chow, C., Jalbrzikowski, M., Jarlbrzkowski, M., Bearden, C. E., Bailey, A., Vangkilde, A., Olsen, L., Olesen, C., Skovby, F., Werge, T. M., Templin, L., Busa, T. & 38 others, Philip, N., Swillen, A., Vermeesch, J. R., Devriendt, K., Schneider, M., Dahoun, S., Eliez, S., Schoch, K., Hooper, S. R., Shashi, V., Samanich, J., Marion, R., van Amelsvoort, T., Boot, E., Klaassen, P., Duijff, S. N., Vorstman, J., Yuen, T., Silversides, C., Chow, E., Bassett, A., Frisch, A., Weizman, A., Gothelf, D., Niarchou, M., van den Bree, M., Owen, M. J., Suñer, D. H., Andreo, J. R., Armando, M., Vicari, S., Digilio, M. C., Auton, A., Kates, W. R., Wang, T., Shprintzen, R. J., Emanuel, B. S. & Morrow, B. E., 7 Mar 2013, In: American Journal of Human Genetics. 92, 3, p. 439-47 9 p.

Research output: Contribution to journal › Journal article › peer-review

Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors

International Consortium for Blood Pressure GWAS & Psychiatric Genomics Consortium Schizophrenia Working Group, Feb 2013, In: American Journal of Human Genetics. 92, 2, p. 197-209 13 p.

Research output: Contribution to journal › Journal article › peer-review

Genetic Schizophrenia Risk Variants Jointly Modulate Total Brain and White Matter Volume

Terwisscha van Scheltinga, A. F., Bakker, S. C., van Haren, N. E. M., Derks, E. M., Buizer-Voskamp, J. E., Boos, H. B. M., Cahn, W., Hulshoff Pol, H. E., Ripke, S., Ophoff, R. A., Kahn, R. S. & the Psychiatric Genome-wide Association Study Consortium, 2013, In: Advances in Biological Psychiatry. 73, 6, p. 525-531

Research output: Contribution to journal › Journal article › peer-review

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

Lee, S. H., DeCandia, T. R., Ripke, S., Yang, J., Sullivan, P. F., Goddard, M. E., Keller, M. C., Visscher, P. M., Wray, N. R., Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ), Hansen, T. F., Ingason, A., Olsen, L., Rasmussen, H. B. & Werge, T. M., 2012, In: Nature Genetics. 44, 3, p. 247-50 4 p.

Research output: Contribution to journal › Journal article › peer-review

Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes

de Jong, S., van Eijk, K. R., Zeegers, D. W. L. H., Strengman, E., Janson, E., Veldink, J. H., van den Berg, L. H., Cahn, W., Kahn, R. S., Boks, M. P. M., Ophoff, R. A. & PGC Schizophrenia (GWAS) Consortium, 2012, In: European Journal of Human Genetics. 20, 9, p. 1004-8 5 p.

Research output: Contribution to journal › Journal article › peer-review

Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms

Fanous, A. H., Zhou, B., Aggen, S. H., Bergen, S. E., Amdur, R. L., Duan, J., Sanders, A. R., Shi, J., Mowry, B. J., Olincy, A., Amin, F., Cloninger, C. R., Silverman, J. M., Buccola, N. G., Byerley, W. F., Black, D. W., Freedman, R., Dudbridge, F., Holmans, P. A., Ripke, S. & 8 others, Gejman, P. V., Kendler, K. S., Levinson, D. F., Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium, Hansen, T. F., Werge, T. M., Olsen, L. & Rasmussen, H. B., 2012, In: American Journal of Psychiatry. 169, 12, p. 1309-17 9 p.

Research output: Contribution to journal › Journal article › peer-review