Research output per year
Research output per year
- 49 results
Search results
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2023
Estimating tissue-specific TNF mRNA levels prior to anti-TNFα treatment may support therapeutic optimisation in IBD patients
James, J. P., Nielsen, B. S., Langholz, E., Malham, M., Høgdall, E. & Riis, L. B., 28 May 2023, (E-pub ahead of print) In: Scandinavian Journal of Gastroenterology. p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2022
COLAR: open-label clinical study of IL-6 blockade with tocilizumab for the treatment of immune checkpoint inhibitor-induced colitis and arthritis
Holmstroem, R. B., Nielsen, O. H., Jacobsen, S., Riis, L. B., Theile, S., Bjerrum, J. T., Vilmann, P., Johansen, J. S., Boisen, M. K., Eefsen, R. H. L., Marie Svane, I., Nielsen, D. L. & Chen, I. M., 1 Sep 2022, In: Journal for ImmunoTherapy of Cancer. 10, 9, e005111.Research output: Contribution to journal › Journal article › Research › peer-review
14 Citations (Scopus) -
Danish Society for Gastroenterology and Hepatology's clinical recommendations for colonoscopic surveillance for colorectal dysplasia and cancer in patients with inflammatory bowel disease
Ward, D., Neumann, A., Hendel, J. W., Riis, L. B., Tøttrup, A., Jess, T. & Aalykke, C., Apr 2022, In: Scandinavian Journal of Gastroenterology. 57, 4, p. 457-464 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipidomic Trajectories Characterize Delayed Mucosal Wound Healing in Quiescent Ulcerative Colitis and Identify Potential Novel Therapeutic Targets
Bjerrum, J. T., Wang, Y., Zhang, J., Riis, L. B., Nielsen, O. H. & Seidelin, J. B., 14 Feb 2022, In: International journal of biological sciences. 18, 5, p. 1813-1828 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2021
Acute Experimental Barrier Injury Triggers Ulcerative Colitis-Specific Innate Hyperresponsiveness and Ulcerative Colitis-Type Microbiome Changes in Humans
Seidelin, J. B., Bahl, M. I., Licht, T. R., Mead, B. E., Karp, J. M., Johansen, J. V., Riis, L. B., Galera, M. R., Woetmann, A. & Bjerrum, J. T., Jan 2021, In: Cellular and molecular gastroenterology and hepatology. 12, 4, p. 1281-1296 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
Adoptive cell therapy with tumor-infiltrating lymphocytes supported by checkpoint inhibition across multiple solid cancer types
Kverneland, A. H., Chamberlain, C. A., Borch, T. H., Nielsen, M., Mørk, S. K., Kjeldsen, J. W., Lorentzen, C. L., Jørgensen, L. P., Riis, L. B., Yde, C. W., Met, Ö., Donia, M. & Marie Svane, I., 4 Oct 2021, In: Journal for ImmunoTherapy of Cancer. 9, 10, e003499.Research output: Contribution to journal › Journal article › Research › peer-review
18 Citations (Scopus) -
Identification, isolation and analysis of human gut-associated lymphoid tissues
Jørgensen, P. B., Fenton, T. M., Mörbe, U. M., Riis, L. B., Jakobsen, H. L., Nielsen, O. H. & Agace, W. W., Apr 2021, In: Nature protocols. 16, 4, p. 2051-2067 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
21 Citations (Scopus) -
Mucosal microRNAs relate to age and severity of disease in ulcerative colitis
Malham, M., James, J. P., Jakobsen, C., Hoegdall, E., Holmstroem, K., Wewer, V., Nielsen, B. S. & Riis, L. B., 1 Mar 2021, In: Aging. 13, 5, p. 6359-6374 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
3 Citations (Scopus) -
Real-life evaluation of histologic scores for Ulcerative Colitis in remission
Arkteg, C. B., Sørbye, S. W., Riis, L. B., Dalen, S. M., Florholmen, J. & Goll, R., 8 Mar 2021, In: PLoS One. 16, 3, e0248224.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
Telomere dysfunction instigates inflammation in inflammatory bowel disease
Chakravarti, D., Lee, R., Multani, A. S., Santoni, A., Keith, Z., Hsu, W-H., Chang, K., Reyes, L., Rashid, A., Wu, C-J., Li, J., Zhang, J., Shim, H. S., Chandra, K., Deng, P., Spring, D. J., Nielsen, O. H., Riis, L. B., Mayigegowda, K. K., Blutt, S. E., & 9 others, 20 Jul 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 29, e2024853118.Research output: Contribution to journal › Journal article › Research › peer-review
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THE MUCOSAL MICRORNA PROFILE RELATES TO AGE AND SEVERITY OF DISEASE IN PATIENTS WITH ULCERATIVE COLITIS
Malham, M., James, J., Jakobsen, C., Hogdall, E., Holmstroem, K., Wewer, V., Nielsen, B. S. & Riis, L., Jan 2021, In: Inflammatory Bowel Diseases. 27, p. S11-S11Research output: Contribution to journal › Journal article › Research › peer-review
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Wnt5a expression and prognosis in stage II-III colon cancer
Lund, C. M., Dyhl-Polk, A., Nielsen, D. L. & Riis, L. B., Jan 2021, In: Translational Oncology. 14, 1, p. 100892 100892.Research output: Contribution to journal › Journal article › Research › peer-review
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2020
A fully defined 3D matrix for ex vivo expansion of human colonic organoids from biopsy tissue
Bergenheim, F., Fregni, G., Buchanan, C. F., Riis, L. B., Heulot, M., Touati, J., Seidelin, J. B., Rizzi, S. C. & Nielsen, O. H., Dec 2020, In: Biomaterials. 262, p. 120248Research output: Contribution to journal › Journal article › Research › peer-review
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Altered Structural Expression and Enzymatic Activity Parameters in Quiescent Ulcerative Colitis: Are These Potential Normalization Criteria?
Kjærgaard, S., Damm, M. M. B., Chang, J., Riis, L. B., Rasmussen, H. B., Hytting-Andreasen, R., Krug, S. M., Schulzke, J-D., Bindslev, N. & Hansen, M. B., 10 Mar 2020, In: International Journal of Molecular Sciences. 21, 5Research output: Contribution to journal › Journal article › Research › peer-review
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Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity
Fenton, T. M., Jørgensen, P. B., Niss, K., Rubin, S. J. S., Mörbe, U. M., Riis, L. B., Da Silva, C., Plumb, A., Vandamme, J., Jakobsen, H. L., Brunak, S., Habtezion, A., Nielsen, O. H., Johansson-Lindbom, B. & Agace, W. W., 17 Mar 2020, In: Immunity. 52, 3, p. 557-570.e6Research output: Contribution to journal › Journal article › Research › peer-review
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2019
Plasma calprotectin is superior to serum calprotectin as a biomarker of intestinal inflammation in ulcerative Colitis
Malham, M., Carlsen, K., Riis, L., Paerregaard, A., Vind, I., Fenger, M. & Wewer, V., Oct 2019, In: Scandinavian Journal of Gastroenterology. 54, 10, p. 1214-1219 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
13 Citations (Scopus) -
2018
COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis
Li, Y., Soendergaard, C., Holmberg, F., Aronoff, D. M., Milne, G., Riis, L. B., Seidelin, J. B., Jensen, K. B. & Nielsen, O. H., Oct 2018, In: EBioMedicine. 36, p. 497-507 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Digital image analysis of pan-cytokeratin stained tumor slides for evaluation of tumor budding in pT1/pT2 colorectal cancer: Results of a feasibility study
Jepsen, R. K., Klarskov, L. L., Lippert, M. F., Novotny, G. W., Hansen, T. P., Christensen, I. J., Høgdall, E. & Riis, L. B., Sep 2018, In: Pathology, research and practice. 214, 9, p. 1273-1281 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamic contrast-enhanced EUS for quantification of tumor perfusion in colonic cancer: a prospective cohort study
Malmstrøm, M. L., Săftoiu, A., Riis, L. B., Hassan, H., Klausen, T. W., Rahbek, M. S., Gögenur, I. & Vilmann, P., Jun 2018, In: Gastrointestinal Endoscopy. 87, 6, p. 1530-1538 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus) -
Early metastatic colorectal cancers show increased tissue expression of miR-17/92 cluster members in the invasive tumor front
Jepsen, R. K., Novotny, G. W., Klarskov, L. L., Bang-Berthelsen, C. H., Haakansson, I. T., Christensen, I. J., Riis, L. B. & Høgdall, E., Oct 2018, In: Human Pathology. 80, p. 231-238 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SMAD4 Protein Expression Is Downregulated in Ileal Epithelial Cells from Patients with Crohn's Disease with Significant Inverse Correlation to Disease Activity
Klausen, P., Karstensen, J. G., Coskun, M., Săftoiu, A., Vilmann, P., Cowland, J. B. & Riis, L. B., 2018, In: Gastroenterology Research and Practice. 2018, p. 9307848Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
The sensitivity of fecal calprotectin in predicting deep remission in ulcerative colitis
Carlsen, K., Riis, L. B., Elsberg, H., Maagaard, L., Thorkilgaard, T., Sørbye, S. W., Jakobsen, C., Wewer, V., Florholmen, J., Goll, R. & Munkholm, P., 2018, In: Scandinavian Journal of Gastroenterology. 53, 7, p. 825-830Research output: Contribution to journal › Journal article › Research › peer-review
25 Citations (Scopus) -
2017
Dual Inhibition of EGFR and VEGF in Heavily Pretreated Patients with Metastatic Colorectal Cancer
Larsen, F. O., Markussen, A., Nielsen, D., Colville-Ebeling, B., Riis, L. B. & Jensen, B. V., 2017, In: Oncology. 93, 3, p. 191-196 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Endoscopic ultrasonography and computed tomography scanning for preoperative staging of colonic cancer
Malmstrøm, M. L., Gögenur, I., Riis, L. B., Hassan, H., Klausen, T. W., Perner, T., Săftoiu, A. & Vilmann, P., Jun 2017, In: International Journal of Colorectal Disease. 32, 6, p. 813-820 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus) -
F-calprotectin and blood markers correlate to Quality of Life in Pediatric Inflammatory Bowel Disease
Carlsen, K., Jakobsen, C., Kallemose, T., Paerregaard, A., Riis, L. B., Munkholm, P. & Wewer, A. V., Nov 2017, In: Journal of Pediatric Gastroenterology and Nutrition. 65, 5, p. 539-545Research output: Contribution to journal › Journal article › Research › peer-review
10 Citations (Scopus) -
Individualized Infliximab Treatment Guided by Patient-managed eHealth in Children and Adolescents with Inflammatory Bowel Disease
Carlsen, K., Houen, G., Jakobsen, C., Kallemose, T., Paerregaard, A., Riis, L. B., Munkholm, P. & Wewer, A. V., 1 Sep 2017, In: Inflammatory Bowel Diseases. 23, 9, p. 1473-1482Research output: Contribution to journal › Journal article › Research › peer-review
20 Citations (Scopus) -
Inflammatory Bowel Disease and Small Bowel Cancer Risk, Clinical Characteristics, and Histopathology: A Population-Based Study
Bojesen, R. D., Riis, L. B., Høgdall, E., Nielsen, O. H. & Jess, T., Dec 2017, In: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 15, 12, p. 1900-1907.e2Research output: Contribution to journal › Journal article › Research › peer-review
49 Citations (Scopus) -
In vivo and ex vivo sentinel node mapping does not identify the same lymph nodes in colon cancer
Andersen, H. S., Bennedsen, A. L. B., Burgdorf, S. K., Eriksen, J. R., Eiholm, S., Toxværd, A., Riis, L. B., Rosenberg, J. & Gögenur, I., Jul 2017, In: International Journal of Colorectal Disease. 32, 7, p. 983-990 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
29 Citations (Scopus) -
Regulation of Laminin γ2 Expression by CDX2 in Colonic Epithelial Cells Is Impaired During Active Inflammation
Coskun, M., Soendergaard, C., Joergensen, S., Dahlgaard, K., Riis, L. B., Nielsen, O. H., Sandelin, A. & Troelsen, J. T., Feb 2017, In: Molecular and Cellular Biochemistry. 118, 2, p. 298-307 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
Self-managed eHealth Disease Monitoring in Children and Adolescents with Inflammatory Bowel Disease: A Randomized Controlled Trial
Carlsen, K., Jakobsen, C., Houen, G., Kallemose, T., Paerregaard, A., Riis, L. B., Munkholm, P. & Wewer, A. V., Mar 2017, In: Inflammatory Bowel Diseases. 23, 3, p. 357-365 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
42 Citations (Scopus) -
2016
Confocal laser endomicroscopy: a novel method for prediction of relapse in Crohn's disease
Karstensen, J. G., Saftoiu, A., Brynskov, J., Hendel, J., Klausen, P. H., Cârtână, T., Klausen, T. W., Riis, L. B. & Vilmann, P., 2016, In: Endoscopy. 48, 4, p. 364 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
29 Citations (Scopus) -
Confocal laser endomicroscopy in ulcerative colitis: a longitudinal study of endomicroscopic changes and response to medical therapy (with videos)
Karstensen, J. G., Săftoiu, A., Brynskov, J., Hendel, J., Ciocalteu, A., Klausen, P., Klausen, T. W., Riis, L. B. & Vilmann, P., Aug 2016, In: Gastrointestinal Endoscopy. 84, 2, p. 279-286.e1Research output: Contribution to journal › Journal article › Research › peer-review
35 Citations (Scopus) -
Incidence of, phenotypes of and survival from small bowel cancer in Denmark, 1994-2010: a population-based study
Bojesen, R. D., Andersson, M., Riis, L. B., Nielsen, O. H. & Jess, T., 4 Feb 2016, In: Journal of Gastroenterology. p. 891-9Research output: Contribution to journal › Journal article › Research › peer-review
22 Citations (Scopus) -
Intra-tumor heterogeneity of microRNA-92a, microRNA-375 and microRNA-424 in colorectal cancer
Jepsen, R. K., Novotny, G. W., Klarskov, L. L., Christensen, I. J., Riis, L. B. & Høgdall, E., Feb 2016, In: Experimental and Molecular Pathology. 100, 1, p. 125-31 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
15 Citations (Scopus) -
Investigating intra-tumor heterogeneity and expression gradients of miR-21, miR-92a and miR-200c and their potential of predicting lymph node metastases in early colorectal cancer
Jepsen, R. K., Novotny, G. W., Klarskov, L. L., Christensen, I. J., Høgdall, E. V. S. & Riis, L. B., 23 Aug 2016, In: Experimental and Molecular Pathology. 101, 2, p. 187-196 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
12 Citations (Scopus) -
2015
Colonoscopy surveillance for dysplasia and colorectal cancer in patients with inflammatory bowel disease
Aalykke, C., Jensen, M. D., Fallingborg, J., Jess, T., Langholz, E., Meisner, S., Andersen, N. N., Riis, L. B., Thomsen, O. Ø. & Tøttrup, A., Jan 2015, In: Danish Medical Bulletin (Online). 62, 1, p. B4995Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Inflammatory bowel disease and cervical neoplasia: a population-based nationwide cohort study
Rungoe, C., Simonsen, J., Riis, L., Frisch, M., Langholz, E. & Jess, T., Apr 2015, In: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 13, 4, p. 693-700.e1Research output: Contribution to journal › Journal article › Research › peer-review
69 Citations (Scopus) -
Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers
Sønderstrup, I. M. H., Nygård, S. B., Poulsen, T. S., Linnemann, D., Stenvang, J., Nielsen, H. J., Bartek, J., Brünner, N., Nørgaard, P. H. & Riis, L., Jun 2015, In: Molecular Oncology. 9, 6, p. 1207-17 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
23 Citations (Scopus) -
2014
Collagenous sprue: a coeliac disease look-alike with different treatment strategy
Soendergaard, C., Riis, L. B. & Nielsen, O. H., 2014, In: B M J Case Reports. 2014Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus) -
Konfokal laserendomikroskopi er en lovende ny endoskopisk metode til diagnostik af kolorektal neoplasi og inflammatorisk tarmsygdom
Translated title of the contribution :Confocal laser endomicroscopy is a new endoscopic technique for diagnosing colorectal neoplasia and inflammatory bowel disease. Research output: Contribution to journal › Journal article › Research › peer-review
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Proximal collagenous gastroenteritides: clinical management. A systematic review
Nielsen, O. H., Riis, L. B., Danese, S., Bojesen, R. D. & Soendergaard, C., Aug 2014, In: Annals of Medicine. 46, 5, p. 311-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
18 Citations (Scopus) -
Transcriptional Analysis of Left-sided Colitis, Pancolitis, and Ulcerative Colitis-associated Dysplasia
Bjerrum, J. T., Nielsen, O. H., Riis, L. B., Pittet, V., Mueller, C., Rogler, G. & Olsen, J., Dec 2014, In: Inflammatory Bowel Diseases. 20, 12, p. 2340-52 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
25 Citations (Scopus) -
2013
ERK controls epithelial cell death receptor signalling and cellular FLICE-like inhibitory protein (c-FLIP) in ulcerative colitis
Seidelin, J. B., Coskun, M., Vainer, B., Riis, L., Soendergaard, C. & Nielsen, O. H., 2013, In: Journal of molecular medicine (Berlin, Germany). 91, 7, p. 839-41 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
17 Citations (Scopus) -
2012
TNF-α-induced down-regulation of CDX2 suppresses MEP1A expression in colitis
Coskun, M., Olsen, A. K., Holm, T. L., Kvist, P. H., Nielsen, O. H., Riis, L. B., Olsen, J. L. & Troelsen, J. T., 2012, In: B B A - Molecular Basis of Disease. 1822, 6, p. 843-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
30 Citations (Scopus) -
2011
Alpha-defensin DEFA1A3 gene copy number elevation in Danish Crohn's disease patients
Jespersgaard, C., Fode, P., Dybdahl, M., Vind, I., Nielsen, O. H., Csillag, C., Munkholm, P., Vainer, B., Riis, L., Elkjaer, M., Pedersen, N., Knudsen, E. & Andersen, P. S., 2011, In: Digestive Diseases and Sciences. 56, 12, p. 3517-24 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
21 Citations (Scopus) -
2010
A Maximum Likelihood Estimator of a Markov Model for Disease Activity in Crohn's Disease and Ulcerative Colitis for Annually Aggregated Partial Observations
Borg, S., Persson, U., Jess, T., Thomsen, O. Ø., Ljung, T., Riis, L. & Munkholm, P., 2010, In: Medical Decision Making. 30, 1, p. 132-142 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Scleroderma induced by paclitaxel
Pedersen, J. V., Jensen, S., Krarup-Hansen, A. & Riis, L., 1 Aug 2010, In: Acta oncologica . 49, 6, p. 866-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
20 Citations (Scopus) -
2009
Toxic hepatitis induced by infliximab in a patient with rheumatoid arthritis with no relapse after switching to etanercept
Carlsen, K. M., Riis, L. & Madsen, O. R., 1 Aug 2009, In: Clinical Rheumatology. 28, 8, p. 1001-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
49 Citations (Scopus) -
2006
Infliximab dependency in a national cohort of children with Crohn's disease
Wewer, V., Riis, L., Vind, I., Husby, S., Munkholm, P. & Paerregaard, A., 2006, In: Journal of Pediatric Gastroenterology and Nutrition. 42, 1, p. 40-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
65 Citations (Scopus)