Personal profile
Expertises
Radiation oncology; Advanced Radiation Therapy; Advanced Imaging; Lymphoma; Head & Neck Cancer; Prognostic Factors; Late Effects of Cancer Treatment;
Main research areas
Radiation Therapy for Lymphoma, use of advanced imaging and treatment techniques with the aim of minimizing long-term toxicity while maintaining the high cure rate;
Radiation Therapy for Head & Neck Cancer, selection patients for intensification of loco-regional treatment and/or intensification of systemic treatment, depending on the risk profile;
Current research
Dose-response relationship for radiation therapy and chemotherapy for lymphomas (with the EORTC Lymphoma Group);
Analysis of recurrence localizations Hodgkin lymphoma and aggressive non-Hodgkin lymphoma;
Analysis of the prognostic value of the metabolic tumour volume in Hodgkin lymphoma and aggressive non-Hodgkinl lymphoma;
Development of evidence based guidelines on radiation therapy for relapsed/refractory lymphoma, proton therapy, plasmacytoma, leukemia, imaging, and target volume modifications, within the worldwide collaboration of the International Lymphoma Radiation Oncology Group;
Prognostic and predictive value of molecular biology (immune histochemistry and DNA analyses) in head & neck cancer;
Prognostic and predictive value of imaging characterstics (PET, CT, MR) in head & neck cancer;
Risk modelling based on clinical, imaging and molecular biology data in head & neck cancer;
Development of a randomized phase II study (based on our previously published Phase I study) of dose-painting in patients with head & neck cancer;
Potential conflicts of interest
None
External positions
University of Copenhagen
2005 → …
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Collaborations and top research areas from the last five years
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Epidemiological evidence for the role of puberty and immune senescence in Hodgkin lymphoma aetiology from 1992 Danish cases
Rostgaard, K., Hamilton-Dutoit, S., Lauridsen, K. L., Ottander, L., Plesner, T. L., Hollander, P., Brown, P., Sjö, L., Johansen, C., Kamper, P., Høgdall, E., d'Amore, F., Specht, L., Jarrett, R. F., McKay, J. D., Hutchings, M., Hjalgrim, L. L., Glimelius, I. & Hjalgrim, H., 2026, In: International Journal of Cancer. 158, 10, p. 2629-2640 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Breaking Down the Barriers for Patients With Cutaneous T-Cell Lymphoma: Current Controversies and Challenges for Radiation Oncologists in 2024
Campbell, B. A., Prince, H. M., Thursky, K., Dabaja, B., Hoppe, R., Specht, L., Morris, S. & Porceddu, S. V., Jan 2025, In: Seminars in Radiation Oncology. 35, 1, p. 110-125 16 p.Research output: Contribution to journal › Review › peer-review
9 Citations (Scopus) -
Efficacy and toxicity of hypofractionated radiation therapy for patients with hematologic malignancies: A COVID-era ILROG collaborative report
Gunther, J. R., Yang, J., Hajj, C., Ng, A. K., Brady, J. L., Cheng, S., Levis, M., Qi, S., George Mikhaeel, N., Ricardi, U., Illidge, T. M., Turin, A., Knafl, M., Specht, L., Dabaja, B. S., Yahalom, J. & International Lymphoma Radiation Oncology Group, Dec 2025, In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 213, 111200.Research output: Contribution to journal › Journal article › Research › peer-review
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Late Cardiac Toxicity After Anthracyclines and Radiotherapy for Lymphoma-A Regression Analysis of Dose-Response
Nygård, L., Vogelius, I. R., Kofoed, K. F., Bentzen, S. & Specht, L., Sept 2025, In: Hematological Oncology. 43, 5, p. e70134 e70134.Research output: Contribution to journal › Journal article › Research › peer-review
3 Citations (Scopus) -
Lymphomas: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up
Eyre, T. A., Cwynarski, K., d'Amore, F., de Leval, L., Dreyling, M., Eichenauer, D. A., Ferreri, A. J. M., Giné, E., Kersten, M. J., Ladetto, M., Specht, L., Thieblemont, C., Walewski, J., Zucca, E., Jerkeman, M. & ESMO Guidelines Committee, Nov 2025, In: Annals of Oncology. 36, 11, p. 1263-1284 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
34 Citations (Scopus)