Research output per year
Research output per year
Personal profile
Expertises
Radiation oncology; Advanced Radiation Therapy; Advanced Imaging; Lymphoma; Head & Neck Cancer; Prognostic Factors; Late Effects of Cancer Treatment;
Main research areas
Radiation Therapy for Lymphoma, use of advanced imaging and treatment techniques with the aim of minimizing long-term toxicity while maintaining the high cure rate;
Radiation Therapy for Head & Neck Cancer, selection patients for intensification of loco-regional treatment and/or intensification of systemic treatment, depending on the risk profile;
Current research
Dose-response relationship for radiation therapy and chemotherapy for lymphomas (with the EORTC Lymphoma Group);
Analysis of recurrence localizations Hodgkin lymphoma and aggressive non-Hodgkin lymphoma;
Analysis of the prognostic value of the metabolic tumour volume in Hodgkin lymphoma and aggressive non-Hodgkinl lymphoma;
Development of evidence based guidelines on radiation therapy for relapsed/refractory lymphoma, proton therapy, plasmacytoma, leukemia, imaging, and target volume modifications, within the worldwide collaboration of the International Lymphoma Radiation Oncology Group;
Prognostic and predictive value of molecular biology (immune histochemistry and DNA analyses) in head & neck cancer;
Prognostic and predictive value of imaging characterstics (PET, CT, MR) in head & neck cancer;
Risk modelling based on clinical, imaging and molecular biology data in head & neck cancer;
Development of a randomized phase II study (based on our previously published Phase I study) of dose-painting in patients with head & neck cancer;
Potential conflicts of interest
None
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A quality control study on involved node radiotherapy in the EORTC/LYSA/FIL H10 Trial on stages I/II Hodgkin lymphoma; lessons learned
Aleman, B. M. P., Ricardi, U., van der Maazen, R. W. M., Meijnders, P., Beijert, M., Boros, A., Izar, F., Janus, C. P. M., Levis, M., Martin, V., Specht, L., Corning, C., Clementel, E., Raemaekers, J. M., Andre, M. P., Federico, M., Fortpied, C. & Girinsky, T., 11 May 2023, (E-pub ahead of print) In: International journal of radiation oncology, biology, physics.Research output: Contribution to journal › Journal article › Research › peer-review
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Brentuximab Vedotin Plus AVD for First-Line Treatment of Early-Stage Unfavorable Hodgkin Lymphoma (BREACH): A Multicenter, Open-Label, Randomized, Phase II Trial
Fornecker, L-M., Lazarovici, J., Aurer, I., Casasnovas, R-O., Gac, A-C., Bonnet, C., Bouabdallah, K., Feugier, P., Specht, L., Molina, L., Touati, M., Borel, C., Stamatoullas, A., Nicolas-Virelizier, E., Pascal, L., Lugtenburg, P., Di Renzo, N., Vander Borght, T., Traverse-Glehen, A., Dartigues, P., & 6 others, 10 Jan 2023, In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 41, 2, p. 327-335 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased incidence rates of positive blood cultures shortly after chemotherapy compared to radiotherapy among individuals treated for solid malignant tumours
Roen, A., Terrones, C., Bannister, W., Helleberg, M., Andersen, M. A., Niemann, C. U., Daugaard, G., Specht, L., Mocroft, A., Reekie, J. & Lundgren, J., Feb 2023, In: Infection. 51, 1, p. 147-157 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prediction of Radiation-induced Lymphopenia following Exposure of the Thoracic Region and Associated Risk of Infections and Mortality
Terrones-Campos, C., Ledergerber, B., Forbes, N., Smith, A. G., Petersen, J., Helleberg, M., Lundgren, J., Specht, L. & Vogelius, I. R., 18 Apr 2023, (E-pub ahead of print) In: Clinical oncology (Royal College of Radiologists (Great Britain)).Research output: Contribution to journal › Journal article › Research › peer-review
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A phase 2 trial of deep-inspiration breath hold in radiotherapy of gastric lymphomas
Petersen, P. M., Rechner, L. A. & Specht, L., Apr 2022, In: Physics and imaging in radiation oncology. 22, p. 137-141 5 p.Research output: Contribution to journal › Journal article › Research › peer-review