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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2019
  2. Published
  3. 2017
  4. Published
  5. Published
  6. Published

    Transcriptional changes induced by bevacizumab combination therapy in responding and non-responding recurrent glioblastoma patients

    Urup, T., Staunstrup, L. M., Michaelsen, S. R., Vitting-Seerup, K., Bennedbæk, M., Toft, A., Olsen, L. R., Jønson, L., Issazadeh-Navikas, S., Broholm, H., Hamerlik, P., Poulsen, H. S. & Lassen, U., 18 Apr 2017, In : B M C Cancer. 17, 1, p. e278

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2016
  8. Published
  9. Published

    Germline Chromothripsis Driven by L1-Mediated Retrotransposition and Alu/Alu Homologous Recombination

    Nazaryan-Petersen, L., Bertelsen, B., Bak, M., Jønson, L., Tommerup, N., Hancks, D. C. & Tümer, Z., Apr 2016, In : Human Mutation. 37, 4, p. 385-95 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published
  11. Published

    Effects of bevacizumab combination therapy on transcriptional changes in responding and non-responding recurrent glioblastoma patients

    Urup, T., Michaelsen, S. R., Staunstrup, L. M., Vitting-Seerup, K., Bennedbæk, M., Toft, A., Jønson, L., Broholm, H., Hamerlik, P., Poulsen, H. S. & Lassen, U., 2016.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  12. 2015
  13. Published
  14. Published

    Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma

    Sibbesen, N. A., Kopp, K. L., Litvinov, I. V., Jønson, L., Willerslev-Olsen, A., Fredholm, S., Petersen, D. L., Nastasi, C., Krejsgaard, T., Lindahl, L. M., Gniadecki, R., Mongan, N. P., Sasseville, D., Wasik, M. A., Iversen, L., Bonefeld, C. M., Geisler, C., Woetmann, A. & Odum, N., 21 Aug 2015, In : Oncotarget. 6, 24, p. 20555-69 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published
  16. Published

    Increasing incidence of base of tongue cancers from 2000 to 2010 due to HPV: the largest demographic study of 210 Danish patients

    Garnaes, E., Kiss, K., Andersen, L., Therkildsen, M. H., Franzmann, M. B., Filtenborg-Barnkob, B., Hoegdall, E., Lajer, C. B., Andersen, E., Specht, L., Joenson, L., Frederiksen, K., Friis-Hansen, L., Nielsen, F. C., Kjaer, S. K., Norrild, B. & Von Buchwald, C. M., 30 Jun 2015, In : B J C. 113, 1, p. 131-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Malignant T cells express lymphotoxin α and drive endothelial activation in cutaneous T cell lymphoma

    Lauenborg, B., Christensen, L., Ralfkiaer, U., Kopp, K. L., Jønson, L., Dabelsteen, S., Bonefeld, C. M., Geisler, C., Gjerdrum, L. M. R., Zhang, Q., Wasik, M. A., Ralfkiaer, E., Ødum, N. & Woetmann, A., 20 Jun 2015, In : Oncotarget. 6, 17, p. 15235-49 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Splicing analysis of 14 BRCA1 missense variants classifies nine variants as pathogenic

    Ahlborn, L. B., Dandanell, M., Steffensen, A. Y., Jønson, L., Nielsen, F. C. & Hansen, T. V. O., Apr 2015, In : Breast Cancer Research and Treatment. 150, 2, p. 289-98 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Identification of six new susceptibility loci for invasive epithelial ovarian cancer

    Kuchenbaecker, K. B., Ramus, S. J., Tyrer, J., Lee, A., Shen, H. C., Beesley, J., Lawrenson, K., McGuffog, L., Healey, S., Lee, J. M., Spindler, T. J., Lin, Y. G., Pejovic, T., Bean, Y., Li, Q., Coetzee, S., Hazelett, D., Miron, A., Southey, M., Terry, M. B., Goldgar, D. E., Buys, S. S., Janavicius, R., Dorfling, C. M., van Rensburg, E. J., Neuhausen, S. L., Ding, Y. C., Hansen, T. V. O., Jønson, L., Gerdes, A-M., Ejlertsen, B., Barrowdale, D., Dennis, J., Benitez, J., Osorio, A., Garcia, M. J., Komenaka, I., Weitzel, J. N., Ganschow, P., Peterlongo, P., Bernard, L., Viel, A., Bonanni, B., Peissel, B., Jensen, A., Kjaer, S. K., Hogdall, E., Hogdall, C., Lundvall, L., Nedergaard, L. & EMBRACE, Feb 2015, In : Nature Genetics. 47, 2, p. 164-71 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Mutations in COA3 cause isolated complex IV deficiency associated with neuropathy, exercise intolerance, obesity, and short stature

    Ostergaard, E., Weraarpachai, W., Ravn, K., Born, A. P., Jønson, L., Duno, M., Wibrand, F., Shoubridge, E. A. & Vissing, J., 20 Jan 2015, In : Journal of Medical Genetics. 52, 3, p. 203-07

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

    Peterlongo, P., Chang-Claude, J., Moysich, K. B., Rudolph, A., Schmutzler, R. K., Simard, J., Soucy, P., Eeles, R. A., Easton, D. F., Hamann, U., Wilkening, S., Chen, B., Rookus, M. A., Schmidt, M. K., van der Baan, F. H., Spurdle, A. B., Walker, L. C., Lose, F., Maia, A-T., Montagna, M., Matricardi, L., Lubinski, J., Jakubowska, A., Gómez Garcia, E. B., Olopade, O. I., Nussbaum, R. L., Nathanson, K. L., Domchek, S. M., Rebbeck, T. R., Arun, B. K., Karlan, B. Y., Orsulic, S., Lester, J., Chung, W. K., Miron, A., Southey, M. C., Goldgar, D. E., Buys, S. S., Janavicius, R., Dorfling, C. M., van Rensburg, E. J., Ding, Y. C., Neuhausen, S. L., Hansen, T. V. O., Gerdes, A-M., Ejlertsen, B., Jønson, L., Osorio, A., Martínez-Bouzas, C., Benitez, J. & EMBRACE, Jan 2015, In : Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 24, 1, p. 308-16 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers

    Blanco, I., Kuchenbaecker, K., Cuadras, D., Wang, X., Barrowdale, D., de Garibay, G. R., Librado, P., Sánchez-Gracia, A., Rozas, J., Bonifaci, N., McGuffog, L., Pankratz, V. S., Islam, A., Mateo, F., Berenguer, A., Petit, A., Català, I., Brunet, J., Feliubadaló, L., Tornero, E., Benítez, J., Osorio, A., Ramón y Cajal, T., Nevanlinna, H., Aittomäki, K., Arun, B. K., Toland, A. E., Karlan, B. Y., Walsh, C., Lester, J., Greene, M. H., Mai, P. L., Nussbaum, R. L., Andrulis, I. L., Domchek, S. M., Nathanson, K. L., Rebbeck, T. R., Barkardottir, R. B., Jakubowska, A., Lubinski, J., Durda, K., Jaworska-Bieniek, K., Claes, K., Van Maerken, T., Díez, O., Hansen, T. V., Jønson, L., Gerdes, A-M., Ejlertsen, B., de la Hoya, M. & Teixeira, 2015, In : P L o S One. 10, 4, p. e0120020

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Identification of a breast cancer family double heterozygote for RAD51C and BRCA2 gene mutations

    Ahlborn, L. B., Steffensen, A. Y., Jønson, L., Djursby, M., Nielsen, F. C., Gerdes, A-M. & Hansen, T. V. O., 2015, In : Familial Cancer. 14, 1, p. 129-133

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2014
  25. Published
  26. Published

    Personalized oncology: genomic screening in phase 1

    Tuxen, I. E. V., Jønson, L., Santoni-Rugiu, E., Hasselby, J. P., Nielsen, F. C. & Lassen, U., Aug 2014, In : APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 122, 8, p. 723-33 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    IMP3 RNP safe houses prevent miRNA-directed HMGA2 mRNA decay in cancer and development

    Jønson, L., Christiansen, J., Hansen, T. V. O., Vikeså, J., Yamamoto, Y. & Nielsen, F. C., 24 Apr 2014, In : Cell Reports. 7, 2, p. 539-51 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers

    Osorio, A., Milne, R. L., Kuchenbaecker, K., Vaclová, T., Pita, G., Alonso, R., Peterlongo, P., Blanco, I., de la Hoya, M., Duran, M., Díez, O., Ramón Y Cajal, T., Konstantopoulou, I., Martínez-Bouzas, C., Andrés Conejero, R., Soucy, P., McGuffog, L., Barrowdale, D., Lee, A., Swe-Brca, Arver, B., Rantala, J., Loman, N., Ehrencrona, H., Olopade, O. I., Beattie, M. S., Domchek, S. M., Nathanson, K., Rebbeck, T. R., Arun, B. K., Karlan, B. Y., Walsh, C., Lester, J., John, E. M., Whittemore, A. S., Daly, M. B., Southey, M., Hopper, J., Terry, M. B., Buys, S. S., Janavicius, R., Dorfling, C. M., van Rensburg, E. J., Steele, L., Neuhausen, S. L., Ding, Y. C., Hansen, T. V. O., Jønson, L., Ejlertsen, B., Gerdes, A-M., Infante, M., Herráez, B., Moreno, L. T., Weitzel, J. N., Herzog, J., Weeman, K., Manoukian, S., Peissel, B., Zaffaroni, D., Scuvera, G., Bonanni, B., Mariette, F., Volorio, S., Viel, A., Varesco, L., Papi, L., Ottini, L., Tibiletti, M. G., Radice, P., Yannoukakos, D., Garber, J., Ellis, S., Frost, D., Platte, R., Fineberg, E., Evans, G., Lalloo, F., Izatt, L., Eeles, R., Adlard, J., Davidson, R., Cole, T., Eccles, D., Cook, J., Hodgson, S., Brewer, C., Tischkowitz, M., Douglas, F., Porteous, M., Side, L., Walker, L., Morrison, P., Donaldson, A., Kennedy, J., Foo, C., Godwin, A. K., Schmutzler, R. K., Wappenschmidt, B., Rhiem, K., Engel, C., Meindl, A., Ditsch, N., Arnold, N., Plendl, H. J., Niederacher, D., Sutter, C., Wang-Gohrke, S., Steinemann, D., Preisler-Adams, S., Kast, K., Varon-Mateeva, R., Gehrig, A., Stoppa-Lyonnet, D., Sinilnikova, O. M., Mazoyer, S., Damiola, F., Poppe, B., Claes, K., Piedmonte, M., Tucker, K., Backes, F., Rodríguez, G., Brewster, W., Wakeley, K., Rutherford, T., Caldés, T., Nevanlinna, H., Aittomäki, K., Rookus, M. A., van Os, T. A. M., van der Kolk, L., de Lange, J. L., Meijers-Heijboer, H. E. J., van der Hout, A. H., van Asperen, C. J., Gómez Garcia, E. B., Hoogerbrugge, N., Collée, J. M., van Deurzen, C. H. M., van der Luijt, R. B., Devilee, P., Hebon, Olah, E., Lázaro, C., Teulé, A., Menéndez, M., Jakubowska, A., Cybulski, C., Gronwald, J., Lubinski, J., Durda, K., Jaworska-Bieniek, K., Johannsson, O. T., Maugard, C., Montagna, M., Tognazzo, S., Teixeira, M. R., Healey, S., Investigators, K., Olswold, C., Guidugli, L., Lindor, N., Slager, S., Szabo, C. I., Vijai, J., Robson, M., Kauff, N., Zhang, L., Rau-Murthy, R., Fink-Retter, A., Singer, C. F., Rappaport, C., Geschwantler Kaulich, D., Pfeiler, G., Tea, M-K., Berger, A., Phelan, C. M., Greene, M. H., Mai, P. L., Lejbkowicz, F., Andrulis, I., Mulligan, A. M., Glendon, G., Toland, A. E., Bojesen, A., Pedersen, I. S., Sunde, L., Thomassen, M., Kruse, T. A., Jensen, U. B., Friedman, E., Laitman, Y., Shimon, S. P., Simard, J., Easton, D. F., Offit, K., Couch, F. J., Chenevix-Trench, G., Antoniou, A. C. & Benitez, J., Apr 2014, In : P L o S Genetics (Online). 10, 4, p. e1004256

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2013
  30. Published

    STAT5-mediated expression of oncogenic miR-155 in cutaneous T-cell lymphoma

    Kopp, K. L., Ralfkiaer, U., Gjerdrum, L. M. R., Helvad, R., Pedersen, I. H., Litman, T., Jønson, L., Hagedorn, P. H., Krejsgaard, T., Gniadecki, R., Bonefeld, C. M., Skov, L., Geisler, C., Wasik, M. A., Ralfkiaer, E., Ødum, N. & Woetmann, A., 15 Jun 2013, In : Cell cycle (Georgetown, Tex.). 12, 12, p. 1939-47 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Next-generation sequencing: proof of concept for antenatal prediction of the fetal Kell blood group phenotype from cell-free fetal DNA in maternal plasma

    Rieneck, K., Bak, M., Jønson, L., Clausen, F. B., Krog, G. R., Tommerup, N., Nielsen, L. K., Hedegaard, M. & Dziegiel, M. H., 3 Apr 2013, In : Transfusion. 53, 11, p. 2892-2898 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    COMPLEXO: identifying the missing heritability of breast cancer via next generation collaboration

    Southey, M. C., Park, D. J., Nguyen-Dumont, T., Campbell, I., Thompson, E., Trainer, A. H., Chenevix-Trench, G., Simard, J., Dumont, M., Soucy, P., Thomassen, M., Jønson, L., Pedersen, I. S., Hansen, T. V. O., Nevanlinna, H., Khan, S., Sinilnikova, O., Mazoyer, S., Lesueur, F., Damiola, F., Schmutzler, R., Meindl, A., Hahnen, E., Dufault, M. R., Chris Chan, T., Kwong, A., Barkardóttir, R., Radice, P., Peterlongo, P., Devilee, P., Hilbers, F., Benitez, J., Kvist, A., Törngren, T., Easton, D., Hunter, D., Lindstrom, S., Kraft, P., Zheng, W., Gao, Y-T., Long, J., Ramus, S., Feng, B-J., Weitzel, J. N., Nathanson, K., Offit, K., Joseph, V., Robson, M., Schrader, K., Wang, S. M. & COMPLEXO, 2013, In : Breast Cancer Research Review. 15, 3, p. e402

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

    Couch, F. J., Wang, X., McGuffog, L., Lee, A. R., Olswold, C., Kuchenbaecker, K. B., Soucy, P., Fredericksen, Z., Barrowdale, D., Dennis, J., Gaudet, M. M., Dicks, E., Kosel, M., Healey, S., Sinilnikova, O. M., Lee, A., Bacot, F., Vincent, D., Hogervorst, F. B. L., Peock, S., Stoppa-Lyonnet, D., Jakubowska, A., Radice, P., Schmutzler, R. K., Domchek, S. M., Piedmonte, M., Singer, C. F., Friedman, E., Thomassen, M., Hansen, T. V. O., Neuhausen, S. L., Szabo, C. I., Blanco, I., Greene, M. H., Karlan, B. Y., Garber, J., Phelan, C. M., Weitzel, J. N., Montagna, M., Olah, E., Andrulis, I. L., Godwin, A. K., Yannoukakos, D., Goldgar, D. E., Caldes, T., Gerdes, A-M., Ejlertsen, B., Nielsen, F. C., Jønson, L., Andersen, M. K. & kConFab Investigators, 2013, In : P L o S Genetics (Online). 9, 3, p. e1003212

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2012
  35. Published

    Characterization of BRCA1 and BRCA2 splicing variants: a collaborative report by ENIGMA consortium members

    Thomassen, M., Blanco, A., Montagna, M., Hansen, T. V. O., Pedersen, I. S., Gutiérrez-Enríquez, S., Menéndez, M., Fachal, L., Santamariña, M., Steffensen, A. Y., Jønson, L., Agata, S., Whiley, P., Tognazzo, S., Tornero, E., Jensen, U. B., Balmaña, J., Kruse, T. A., Goldgar, D. E., Lázaro, C., Diez, O., Spurdle, A. B. & Vega, A., 2012, In : Breast Cancer Research and Treatment. 132, 3, p. 1009-23 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2011
  37. Published

    Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers

    Antoniou, A. C., Kartsonaki, C., Sinilnikova, O. M., Soucy, P., McGuffog, L., Healey, S., Lee, A. R., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Cattaneo, E., Barile, M., Pensotti, V., Pasini, B., Dolcetti, R., Giannini, G., Putignano, A. L., Varesco, L., Radice, P., Mai, P. L., Greene, M. H., Andrulis, I. L., Glendon, G., Ozcelik, H., Thomassen, M., Gerdes, A-M., Kruse, T. A., Birk Jensen, U., Crüger, D. G., Caligo, M. A., Laitman, Y., Milgrom, R., Kaufman, B., Paluch-Shimon, S., Friedman, E., Loman, N., Harbst, K., Lindblom, A., Arver, B., Ehrencrona, H., Melin, B., Nathanson, K. L., Domchek, S. M., Rebbeck, T., Jakubowska, A., Lubinski, J., Hansen, T. V. O., Jønson, L., Ejlertsen, B. & SWE-BRCA, 2011, In : Human Molecular Genetics. 20, 16, p. 3304-21 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers

    Ramus, S. J., Kartsonaki, C., Gayther, S. A., Pharoah, P. D. P., Sinilnikova, O. M., Beesley, J., Chen, X., McGuffog, L., Healey, S., Couch, F. J., Wang, X., Fredericksen, Z., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Roversi, G., Barile, M., Viel, A., Allavena, A., Ottini, L., Papi, L., Gismondi, V., Capra, F., Radice, P., Greene, M. H., Mai, P. L., Andrulis, I. L., Glendon, G., Ozcelik, H., Thomassen, M., Gerdes, A-M., Kruse, T. A., Cruger, D., Jensen, U. B., Caligo, M. A., Olsson, H., Kristoffersson, U., Lindblom, A., Arver, B., Karlsson, P. W., Stenmark Askmalm, M., Borg, A., Neuhausen, S. L., Ding, Y. C., Nathanson, K. L., Domchek, S. M., Hansen, T. V. O., Jønson, L., Ejlertsen, B. & OCGN, 2011, In : National Cancer Institute. Journal (Print). 103, 2, p. 105-16 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Isolation of RNP granules

    Jønson, L., Nielsen, F. C. & Christiansen, J., 2011, In : Methods in Molecular Biology. 703, p. 265-73 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published
  41. 2010
  42. Published
  43. Published

    Identification of a Danish breast/ovarian cancer family double heterozygote for BRCA1 and BRCA2 mutations

    Steffensen, A. Y., Jønson, L., Ejlertsen, B., Gerdes, A-M., Nielsen, F. C. & Hansen, T. V. O., 1 Sep 2010, In : Familial Cancer. 9, 3, p. 283-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

ID: 23703