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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2020
  2. Published

    Aging suppresses sphingosine-1-phosphate chaperone ApoM in circulation resulting in maladaptive organ repair

    Ding, B-S., Yang, D., Swendeman, S. L., Christoffersen, C., Nielsen, L. B., Friedman, S. L., Powell, C. A., Hla, T. & Cao, Z., 22 Jun 2020, In : Developmental Cell. 53, 6, p. 677-690 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2019
  4. Published

    Acute intramyocardial lipid accumulation in rats does not slow cardiac conduction per se

    Jensen, C. F., Bartels, E. D., Braunstein, T. H., Nielsen, L. B., Holstein-Rathlou, N-H., Axelsen, L. N. & Nielsen, M. S., Apr 2019, In : Physiological Reports. 7, 7, e14049.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Effect of menopause and exercise training on plasma apolipoprotein M and sphingosine-1-phosphate

    Yafasova, A., Mandrup, C. M., Egelund, J., Nyberg, M., Stallknecht, B., Hellsten, Y., Nielsen, L. B. & Christoffersen, C., 1 Jan 2019, In : Journal of Applied Physiology. 126, 1, p. 214-220 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    High doses of ANP and BNP exacerbate lipolysis in humans and the lipolytic effect of BNP is associated with cardiac triglyceride content in pigs

    Bartels, E. D., Guo, S., Kousholt, B. S., Larsen, J. R., Hasenkam, J. M., Burnett, J., Nielsen, L. B., Ashina, M. & Goetze, J. P., 2019, In : Peptides. 112, p. 43-47 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2018
  8. Published

    Non-AIDS Comorbidity in People Living with HIV Compared to Uninfected Individuals Ten Years Prior to HIV-Diagnosis

    Ronit, A., Gerstoft, J., Nielsen, L., Mohey, R., Wiese, L., Kvinesdal, B., Obel, N. & Ahlströhm, M. G., Oct 2018, In : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 67, 8, p. 1291-1293 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Apolipoprotein M in patients with chronic kidney disease

    Sørensen, I. M., Bertelsen, M., Freese, E., Lindhard, K., Ullum, H., Feldt-Rasmussen, B., Nielsen, L. B., Christoffersen, C. & Bro, S., Aug 2018, In : Atherosclerosis. 275, p. 304-311 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Differential Effects of Digoxin on Imiquimod-Induced Psoriasis-Like Skin Inflammation on the Ear and Back

    Madsen, M., Pedersen, T. X., Nielsen, L. B., Johansen, C. & Hansen, P. R., Aug 2018, In : Annals of Dermatology . 30, 4, p. 485-488 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Imiquimod-Induced Psoriasis-Like Skin Lesions Do Not Accelerate Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice

    Madsen, M., Hansen, P. R., Nielsen, L. B., Cardoso, R. M., van Eck, M. & Pedersen, T. X., Jun 2018, In : American Journal of Pathology. 188, 6, p. 1486-1496 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Personlig medicin vil involvere alle specialer, og det handler om andet end genomet

    Ullum, H., Hersom, C., Wewer, U., Skøtt, O., Nielsen, L. B. & Rasmussen, L. H., 19 Mar 2018, In : Ugeskrift for Laeger. 180, 12, p. V69884

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity

    Christoffersen, C., Federspiel, C. K., Borup, A., Christensen, P. M., Madsen, A. N., Heine, M., Nielsen, C. H., Kjaer, A., Holst, B., Heeren, J. & Nielsen, L. B., 2 Jan 2018, In : Cell Reports. 22, 1, p. 175-188 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Diet-Induced Abdominal Obesity, Metabolic Changes, and Atherosclerosis in Hypercholesterolemic Minipigs

    Al-Mashhadi, A. L., Poulsen, C. B., von Wachenfeldt, K., Robertson, A-K., Bentzon, J. F., Nielsen, L. B., Thygesen, J., Tolbod, L. P., Larsen, J. R., Moestrup, S. K., Frendéus, B., Mortensen, B., Drouet, L., Al-Mashhadi, R. H. & Falk, E., 2018, In : Journal of Diabetes Research. 2018, p. 6823193

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2017
  16. Published

    ApoB and apoM - New aspects of lipoprotein biology in uremia-induced atherosclerosis

    Christoffersen, C., Bartels, E. D., Aarup, A., Nielsen, L. B. & Pedersen, T. X., 5 Dec 2017, In : European Journal of Pharmacology. 816, p. 154-160 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Apolipoprotein M mediates sphingosine-1-phosphate efflux from erythrocytes

    Christensen, P. M., Bosteen, M. H., Hajny, S., Nielsen, L. B. & Christoffersen, C., 8 Nov 2017, In : Scientific Reports. 7, 1, p. 14983

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Effects of apolipoprotein M in uremic atherosclerosis

    Bosteen, M. H., Madsen Svarrer, E. M., Bisgaard, L. S., Martinussen, T., Madsen, M., Nielsen, L. B., Christoffersen, C. & Pedersen, T. X., Oct 2017, In : Atherosclerosis. 265, p. 93-101 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Uremia does not affect neointima formation in mice

    Aarup, A., Nielsen, C. H., Bisgaard, L. S., Bot, I., El-Ali, H. H., Kjaer, A., Nielsen, L. B. & Pedersen, T. X., 26 Jul 2017, In : Scientific Reports. 7, 1, p. 6496

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The Bipolar Illness Onset study: research protocol for the BIO cohort study

    Kessing, L. V., Munkholm, K., Faurholt-Jepsen, M., Miskowiak, K. W., Nielsen, L. B., Frikke-Schmidt, R., Ekstrøm, C. T., Winther, O., Pedersen, B. K., Poulsen, H. E., McIntyre, R. S., Kapczinski, F., Gattaz, W. F., Bardram, J., Frost, M., Mayora, O., Knudsen, G. M., Phillips, M. & Vinberg, M., 23 Jun 2017, In : B M J Open. 7, 6, p. e015462

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Uremia modulates the phenotype of aortic smooth muscle cells

    Madsen, M., Aarup, A., Albinsson, S., Hartvigsen, K., Sørensen, C. M., Turczynska, K., Nielsen, L. B. & Pedersen, T. X., Feb 2017, In : Atherosclerosis. 257, p. 64-70 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2016
  23. Published

    HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver

    Ding, B-S., Liu, C. H., Sun, Y., Chen, Y., Swendeman, S. L., Jung, B., Chavez, D., Cao, Z., Christoffersen, C., Nielsen, L. B., Schwab, S. R., Rafii, S. & Hla, T., 22 Dec 2016, In : JCI Insight. 1, 21, p. e87058

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Bone marrow-derived and peritoneal macrophages have different inflammatory response to oxLDL and M1/M2 marker expression - implications for atherosclerosis research

    Bisgaard, L. S., Mogensen, C. K., Rosendahl, A., Cucak, H., Nielsen, L. B., Rasmussen, S. E. & Pedersen, T. X., 13 Oct 2016, In : Scientific Reports. 6, p. 35234

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Hypoxia-Inducible Factor-1α Expression in Macrophages Promotes Development of Atherosclerosis

    Aarup, A., Pedersen, T. X., Junker, N., Christoffersen, C., Bartels, E. D., Madsen, M., Nielsen, C. H. & Nielsen, L. B., Sep 2016, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 9, p. 1782-90 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Treatment with a human recombinant monoclonal IgG antibody against oxidized LDL in atherosclerosis-prone pigs reduces cathepsin S in coronary lesions

    Poulsen, C. B., Al-Mashhadi, A. L., von Wachenfeldt, K., Bentzon, J. F., Nielsen, L. B., Al-Mashhadi, R. H., Thygesen, J., Tolbod, L., Larsen, J. R., Frøkiær, J., Tawakol, A., Vucic, E., Fredrickson, J., Baruch, A., Frendéus, B., Robertson, A-K. L., Moestrup, S. K., Drouet, L. & Falk, E., 15 Jul 2016, In : International Journal of Cardiology. 215, p. 506-15 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Effect of 12-O-tetradecanoylphorbol-13-acetate-induced psoriasis-like skin lesions on systemic inflammation and atherosclerosis in hypercholesterolaemic apolipoprotein E deficient mice

    Madsen, M., Hansen, P. R., Nielsen, L. B., Hartvigsen, K., Pedersen, A. E., Christensen, J. P., Pedersen, A. A. & Pedersen, T. X., 11 Jul 2016, In : B M C Dermatology. 16, 1, p. 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Impaired endothelial barrier function in apolipoprotein M-deficient mice is dependent on sphingosine-1-phosphate receptor 1

    Christensen, P. M., Liu, C. H., Swendeman, S. L., Obinata, H., Qvortrup, K., Nielsen, L. B., Hla, T., Di Lorenzo, A. & Christoffersen, C., Jun 2016, In : FASEB Journal. 30, 6, p. 2351-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published
  30. Published

    Sphingosine-1-phosphate reduces ischaemia-reperfusion injury by phosphorylating the gap junction protein Connexin43

    Morel, S., Christoffersen, C., Axelsen, L. N., Montecucco, F., Rochemont, V., Frias, M. A., Mach, F., James, R. W., Naus, C. C., Chanson, M., Lampe, P. D., Nielsen, M. S., Nielsen, L. B. & Kwak, B. R., 1 Mar 2016, In : Cardiovascular Research. 109, 3, p. 385-96 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Liraglutide Reduces Both Atherosclerosis and Kidney Inflammation in Moderately Uremic LDLr-/- Mice

    Bisgaard, L. S., Høybye Bosteen, M., Fink, L. N., Sørensen, C. M., Rosendahl, A., Mogensen, C. K., Rasmussen, S. E., Rolin, B., Nielsen, L. B. & Pedersen, T. X., 2016, In : P L o S One. 11, 12, p. e0168396

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Urinary apolipoprotein M as a biomarker of acute kidney injury in children undergoing heart surgery

    Svarrer, E. M. M., Andersen, H. Ø., Helvind, M., Slagman, M. C. J., Navis, G., Dullaart, R. P. F., Dahlbäck, B. & Nielsen, L. B., 2016, In : Biomarkers in Medicine. 10, 1, p. 81-93 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. 2015
  34. Published

    Altered Metabolism of LDL in the Arterial Wall Precedes Atherosclerosis Regression

    Bartels, E. D., Christoffersen, C., Lindholm, M. W. & Nielsen, L. B., 6 Nov 2015, In : Circulation Research. 117, 11, p. 933-42 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Kjeld Jørgensen

    Rehfeld, J. F., Hilsted, L. M. & Nielsen, L. B., 17 Aug 2015, In : Ugeskrift for læger. 177/17, p. 1643

    Research output: Contribution to journalComment/debateCommunication

  36. Published

    Protein unfolding allows use of commercial antibodies in an apolipoprotein M sandwich ELISA

    Bosteen, M. H., Dahlbäck, B., Nielsen, L. B. & Christoffersen, C., Mar 2015, In : Journal of Lipid Research. 56, 3, p. 754-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Apolipoprotein M in lipid metabolism and cardiometabolic diseases

    Borup, A., Christensen, P. M., Nielsen, L. B. & Christoffersen, C., Feb 2015, In : Current Opinion in Lipidology. 26, 1, p. 48-55 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

    Axelsen, L. N., Calloe, K., Braunstein, T. H., Riemann, M., Hofgaard, J. P., Liang, B., Jensen, C. F., Olsen, K. B., Bartels, E. D., Baandrup, U., Jespersen, T., Nielsen, L. B., Holstein-Rathlou, N-H. & Nielsen, M. S., 2015, In : Cardiovascular Diabetology. 14, p. 87

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Genetic analysis of ligation-induced neointima formation in an F2 intercross of C57BL/6 and FVB/N inbred mouse strains

    Östergren, E-B. C., Shim, J., Larsen, J. V., Nielsen, L. B. & Bentzon, J. F., 2015, In : P L o S One. 10, 4, p. e0121899

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2014
  41. Published

    Polybrominated diphenyl ethers and perfluoroalkyl substances in serum of pregnant women: levels, correlations, and potential health implications

    Vorkamp, K., Nielsen, F., Kyhl, H. B., Husby, S., Nielsen, L. B., Barington, T., Andersson, A-M. & Jensen, T. K., Jul 2014, In : Archives of Environmental Contamination and Toxicology. 67, 1, p. 9-20 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Skeletal muscle apolipoprotein B expression reduces muscular triglyceride accumulation

    Bartels, E. D., Ploug, T., Størling, J., Mandrup-Poulsen, T. & Nielsen, L. B., Jun 2014, In : Scandinavian Journal of Clinical & Laboratory Investigation. 74, 4, p. 351-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    NT-ProBNP Independently Predicts Long-Term Mortality in Patients Admitted for Coronary Angiography

    Ruwald, M. H., Goetze, J. P., Bech, J., Nielsen, O. W., Madsen, B. K., Nielsen, L. B., Mouridsen, M., Ruwald, A-C. H., Madsen, J. K. & Pedersen, S., Jan 2014, In : Angiology Frontier. 65, p. 31-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Effect of atrial natriuretic peptide on lipolysis in the mouse heart

    Bartels, E. D., Bisgaard, L. S., Christoffersen, C. & Nielsen, L. B., 2014, In : Cardiovascular Endocrinology. Volume 3 - Issue 3 - p 92-97, p. 92-97

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2013
  46. Published

    Apolipoprotein M: bridging HDL and endothelial function

    Christoffersen, C. & Nielsen, L. B., Aug 2013, In : Current Opinion in Lipidology. 24, 4, p. 295-300 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Apolipoprotein M promotes mobilization of cellular cholesterol in vivo

    Elsøe, S., Christoffersen, C., Luchoomun, J., Turner, S. & Nielsen, L. B., Jul 2013, In : Biochimica et Biophysica Acta. 1831, 7, p. 1287-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Reply to Simvastatin Effects on Skeletal Muscle: Study Design and Validity

    Larsen, S., Stride, N. O., Hey-Mogensen, M., Hansen, C., Bang, L. E., Bundgaard, H., Nielsen, L. B., Helge, J. W. & Dela, F., 11 Jun 2013, In : Journal of the American College of Cardiology. 61, 23, p. 2393

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Osteopontin deficiency dampens the pro-atherogenic effect of uraemia

    Pedersen, T. X., Madsen, M. D., Junker, N., Christoffersen, C., Vikeså, J., Bro, S., Hultgårdh-Nilsson, A. & Nielsen, L. B., 1 Jun 2013, In : Cardiovascular Research. 98, 3, p. 352-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Application of Molecular Genetics to the Investigation of Inherited Bleeding Disorders

    Lethagen, S. R., Dunø, M. & Nielsen, L. B., 26 Feb 2013, Application of Molecular Genetics to the Investigation of Inherited Bleeding Disorders. http://onlinelibrary.wiley.com/book/10.1002/9781118543467: Blackwell Publishing Ltd, p. 115-123 9 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  51. Published
  52. Published

    Simvastatin effects on skeletal muscle: relation to decreased mitochondrial function and glucose intolerance

    Larsen, S., Stride, N. O., Hey-Mogensen, M., Hansen, C., Bang, L. E., Bundgaard, H., Nielsen, L. B., Helge, J. W. & Dela, F., 8 Jan 2013, In : Journal of the American College of Cardiology. 61, 1, p. 44-53 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant

    Al-Mashhadi, R. H., Sørensen, C., Kragh, P. M., Christoffersen, C., Mortensen, M., Tolbod, L. P., Thim, T., Du, Y., Li, J., Liu, Y., Moldt, B., Schmidt, M., Vajta, G., Larsen, T. K., Purup, S., Bolund, L., Nielsen, L. B., Callesen, H., Falk, E., Mikkelsen, J. G. & Bentzon, J. F., 2 Jan 2013, In : Science translational medicine. 5, 166, p. 166ra1

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published
  55. Published

    The apolipoprotein m-sphingosine-1-phosphate axis: biological relevance in lipoprotein metabolism, lipid disorders and atherosclerosis

    Arkensteijn, B. W. C., Berbée, J. F. P., Rensen, P. C. N., Nielsen, L. B. & Christoffersen, C., 2013, In : International Journal of Molecular Sciences (Online). 14, 3, p. 4419-31 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. 2012
  57. Published

    Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL

    Elsøe, S., Ahnström, J., Christoffersen, C., Hoofnagle, A. N., Plomgaard, P., Heinecke, J. W., Binder, C. J., Björkbacka, H., Dahlbäck, B. & Nielsen, L. B., 1 Mar 2012, In : Atherosclerosis. 221,1, 91-97

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    A little+a little equals a lot-Does the combination of modest increases of liver inflammation and plasma cholesterol augment atherosclerosis?

    Pedersen, T. X. & Nielsen, L. B., 2012, In : Atherosclerosis. 220, 2, p. 321-2 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Apolipoprotein M - a new biomarker in sepsis

    Christoffersen, C. & Nielsen, L. B., 2012, In : Critical Care (Online Edition). 16, 3, p. 126

    Research output: Contribution to journalJournal articleResearchpeer-review

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