Research output per year
Research output per year
Personal profile
Brief presentation
The Almstrup group is mainly located at the Department of Growth and Reproduction, at Copenhagen University Hospital - Rigshospitalet but is also affiliated with the Department of Cellular and Molecular Medicine, at University of Copenhagen. Our research focus on studies that connect genetic and epigenetic variation to reproductive endpoints, testicular gene expression and functional studies of sperm cells.
Group homepage: https://www.rigshospitalet.dk/almstrup
Main research areas
Genetic and epigenetic variation in relation to reproductive endpoints, testicular gene expression and functional studies of sperm cells.
Teaching and areas of guidance
Medical genetics course (Medicine and Molecular Biomedicine)
PhD course in Genetics of Reproduction, May 16-17, 2022
Graduate programmes: Life Cycle in Medicine and Cellular & Genetic Medicine
Potential conflicts of interest
None
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Variant PNLDC1, Defective piRNA Processing, and Azoospermia
Nagirnaja, L., Mørup, N., Nielsen, J. E., Stakaitis, R., Golubickaite, I., Oud, M. S., Winge, S. B., Carvalho, F., Aston, K. I., Khani, F., van der Heijden, G. W., Marques, C. J., Skakkebaek, N. E., Rajpert-De Meyts, E., Schlegel, P. N., Jørgensen, N., Veltman, J. A., Lopes, A. M., Conrad, D. F. & Almstrup, K., 19 Aug 2021, In: The New England journal of medicine. 385, 8, p. 707-719 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
25 Citations (Scopus) -
Diverse monogenic subforms of human spermatogenic failure
Nagirnaja, L., Lopes, A. M., Charng, W-L., Miller, B., Stakaitis, R., Golubickaite, I., Stendahl, A., Luan, T., Friedrich, C., Mahyari, E., Fadial, E., Kasak, L., Vigh-Conrad, K., Oud, M. S., Xavier, M. J., Cheers, S. R., James, E. R., Guo, J., Jenkins, T. G., Riera-Escamilla, A., & 29 others, 26 Dec 2022, In: Nature Communications. 13, 1, 7953.Research output: Contribution to journal › Journal article › Research › peer-review
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The molecular evolution of spermatogenesis across mammals
Murat, F., Mbengue, N., Winge, S. B., Trefzer, T., Leushkin, E., Sepp, M., Cardoso-Moreira, M., Schmidt, J., Schneider, C., Mößinger, K., Brüning, T., Lamanna, F., Belles, M. R., Conrad, C., Kondova, I., Bontrop, R., Behr, R., Khaitovich, P., Pääbo, S., Marques-Bonet, T., & 4 others, Jan 2023, In: Nature. 613, 7943, p. 308-316 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Environmental factors in declining human fertility
Skakkebæk, N. E., Lindahl-Jacobsen, R., Levine, H., Andersson, A-M., Jørgensen, N., Main, K. M., Lidegaard, Ø., Priskorn, L., Holmboe, S. A., Bräuner, E. V., Almstrup, K., Franca, L. R., Znaor, A., Kortenkamp, A., Hart, R. J. & Juul, A., Mar 2022, In: Nature reviews. Endocrinology. 18, 3, p. 139-157 19 p.Research output: Contribution to journal › Review › peer-review
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Application of miRNAs in the diagnosis and monitoring of testicular germ cell tumours
Almstrup, K., Lobo, J., Mørup, N., Belge, G., Rajpert-De Meyts, E., Looijenga, L. H. J. & Dieckmann, K-P., Apr 2020, In: Nature reviews. Urology. 17, 4, p. 201-213 13 p.Research output: Contribution to journal › Review › peer-review
50 Citations (Scopus)
Prizes
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Royan international research award on Reproductive Biomedicine and Stem Cells
Almstrup, Kristian (Recipient), 2012
Prize: Prizes, scholarships, distinctions
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Publons Peer Reviewer Award
Almstrup, Kristian (Recipient), 2016
Prize: Prizes, scholarships, distinctions
Activities
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Andrology (Journal)
Kristian Almstrup (Reviewer)
1 Jan 2023Activity: Publication peer-review and editorial work › Editor of Research journal › Research
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Genetics identifies piRNAs as essential for human spermatogenesis
Kristian Almstrup (Lecturer)
21 Sep 2022Activity: Talk or presentation › Lecture and oral contribution
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Genetics identifies piRNAs as essential for male germ cells
Kristian Almstrup (Lecturer)
16 May 2022Activity: Talk or presentation › Lecture and oral contribution
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Genetics of Reproduction
Kristian Almstrup (Organizer)
16 May 2022 → 17 May 2022Activity: Participating in or organising an event › Organisation of and participation in conference
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Variant PNLDC1, defective piRNA processing, and azoospermia; a small genetic mutation with a huge impact on male sperm production
Kristian Almstrup (Lecturer)
24 Nov 2021Activity: Talk or presentation › Lecture and oral contribution