Research output per year
Research output per year
Personal profile
Expertises
Cellular based assays.
Main research areas
Endocytic receptors; Collagen receptors; Interaction between cells and extracellular matrix.
Current research
I am working to identify biologically relevant ligands of an endocytic receptor, know to play important role in fibrosis and certain cancers. I am working on a mass spectrometry-based proteomics screen aiming at identifying unknown ligands taken up by this receptor in vitro and in vivo. Methods will include several techniques within cell biology, molecular biology and protein chemistry as well as work with mice to clarify protein function in vivo.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A proteomics-based survey reveals thrombospondin-4 as a ligand regulated by the mannose receptor in the injured lung
Nørregaard, K. S., Jürgensen, H. J., Heltberg, S. S., Gårdsvoll, H., Bugge, T. H., Schoof, E. M., Engelholm, L. H. & Behrendt, N., May 2024, In: Journal of Biological Chemistry. 300, 5, 107284.Research output: Contribution to journal › Journal article › Research › peer-review
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The endocytic receptor uPARAP is a regulator of extracellular thrombospondin-1
Nørregaard, K. S., Jürgensen, H. J., Ingvarsen, S. Z., Heltberg, S. S., Hagensen, C. E., Gårdsvoll, H., Madsen, D. H., Jensen, O. N., Engelholm, L. H. & Behrendt, N., Aug 2022, In: Matrix biology : journal of the International Society for Matrix Biology. 111, p. 307-328 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus) -
Osteosarcoma and Metastasis Associated Bone Degradation-A Tale of Osteoclast and Malignant Cell Cooperativity
Nørregaard, K. S., Jürgensen, H. J., Gårdsvoll, H., Engelholm, L. H., Behrendt, N. & Søe, K., Jul 2021, In: International Journal of Molecular Sciences. 22, 13, 6865.Research output: Contribution to journal › Review › peer-review
32 Citations (Scopus) -
A Survey of Novel Ligands of the Members of the Mannose Receptor Protein Family
Nørregaard, K. S., Apr 2020, Eget Forlag. 118 p.Research output: Book/Report › Ph.D. thesis
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Cellular uptake of collagens and implications for immune cell regulation in disease
Jürgensen, H. J., van Putten, S., Nørregaard, K. S., Bugge, T. H., Engelholm, L. H., Behrendt, N. & Madsen, D. H., 25 Feb 2020, In: Cellular and molecular life sciences. 77, 16, p. 3161-3176 16 p.Research output: Contribution to journal › Review › peer-review
26 Citations (Scopus)