Research output per year
Research output per year
Personal profile
Expertises
Safety and efficacy of biological treatment in rheumatoid arthritis,
epidemiology
Main research areas
Safety and efficacy of biological treatment in rheumatoid arthritis,
epidemiology
Current research
Efficacy and safety of biological treatments in rheumatoid arthritis
PhD project
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease which often causes pain, functional impairment and potentially irreversible joint destructions. Treatment of patients with RA has improved over the last two decades not least due to the introduction of biological agents (bDMARDs). However, lack of treatment effect or adverse events occur in up to 30% of bDMARD treated patients and bDMARDs have raised safety concerns. Observational studies allow the study of long-term efficacy and safety of biologics. By linkage with national registries outcomes such as hospitalized infections can be studied and adjustment for comorbidities and other potential confounders can be done. This gives an excellent opportunity to further characterize the patients and to study the safety and efficacy of bDMARDs.
Based on DANBIO and national registries, the PhD study aims at investigating efficacy and safety of biological treatments in patients with RA.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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One-year treatment outcomes of secukinumab versus tumor necrosis factor inhibitors in Spondyloarthritis: Results From Five Nordic Biologic Registries Including More Than 10,000 Treatment Courses
Glintborg, B., Lindstrom, U., De Giuseppe, D., Provan, S. A., Gudbjornsson, B., Hetland, M. L., Michelsen, B., Wallman, J., Aaltonen, K., Hokkanen, A-M., Nordström, D., Jørgensen, T. S., Hansen, R. L., Jon Geirsson, A., Grøn, K., Krogh, N. S., Askling, J., Kristensen, L. E., Jacobsson, L. & DANBIO (Denmark), ARTIS/SRQ (Sweden), ICEBIO (Iceland), ROB-FIN (Finland), NOR-DMARD (Norway) registries, May 2022, In: Arthritis Care & Research. 74, 5, p. 748-758 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Short-term, intermediate-term and long-term risks of acute coronary syndrome in cohorts of patients with RA starting biologic DMARDs: results from four Nordic countries
Delcoigne, B., Ljung, L., Provan, S. A., Glintborg, B., Hetland, M. L., Grøn, K. L., Peltomaa, R., Relas, H., Turesson, C., Gudbjornsson, B., Michelsen, B. & Askling, J., Jun 2022, In: Annals of the Rheumatic Diseases. 81, 6, p. 789-797 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of treatment retention and response to secukinumab versus tumour necrosis factor inhibitors in psoriatic arthritis
Lindström, U., Glintborg, B., Di Giuseppe, D., Schjødt Jørgensen, T., Gudbjornsson, B., Lederballe Grøn, K., Aarrestad Provan, S., Michelsen, B., Lund Hetland, M., Wallman, J. K., Nordström, D., Trokovic, N., Love, T. J., Krogh, N. S., Askling, J., Jacobsson, L. T. H. & Kristensen, L. E., 2 Aug 2021, In: Rheumatology (Oxford, England). 60, 8, p. 3635-3645 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus) -
Risk of serious infections in arthritis patients treated with biological drugs: a matched cohort study and development of prediction model
Krabbe, S., Grøn, K. L., Glintborg, B., Nørgaard, M., Mehnert, F., Jarbøl, D. E., Østergaard, M. & Hetland, M. L., 2 Aug 2021, In: Rheumatology (Oxford, England). 60, 8, p. 3834-3844 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Short- and longer-term risks for acute coronary syndrome in patients with rheumatoid arthritis starting treatment with disease-modifying anti-rheumatic drugs. A collaborative observational head-to-head study across five Nordic rheumatology registers
Delcoigne, B., Ljung, L., Provan, SA., Glintborg, B., Grøn, K. L., Hetland, M. L., Krogh, NS., Trokovic, N., Relas, H., Turesson, C. & Michelsen, B., 2021, In: Annals of the Rheumatic Diseases. 80, Supplement 1, p. 63-4 2 p., OP0114.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review