Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2019
  2. E-pub ahead of print

    Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

    Dominguez-Valentin, M., Sampson, J. R., Seppälä, T. T., Ten Broeke, S. W., Plazzer, J-P., Nakken, S., Engel, C., Aretz, S., Jenkins, M. A., Sunde, L., Bernstein, I., Capella, G., Balaguer, F., Thomas, H., Evans, D. G., Burn, J., Greenblatt, M., Hovig, E., de Vos Tot Nederveen Cappel, W. H., Sijmons, R. H., Bertario, L., Tibiletti, M. G., Cavestro, G. M., Lindblom, A., Della Valle, A., Lopez-Köstner, F., Gluck, N., Katz, L. H., Heinimann, K., Vaccaro, C. A., Büttner, R., Görgens, H., Holinski-Feder, E., Morak, M., Holzapfel, S., Hüneburg, R., Knebel Doeberitz, M. V., Loeffler, M., Rahner, N., Schackert, H. K., Steinke-Lange, V., Schmiegel, W., Vangala, D., Pylvänäinen, K., Renkonen-Sinisalo, L., Hopper, J. L., Win, A. K., Haile, R. W., Lindor, N. M., Gallinger, S., Le Marchand, L., Newcomb, P. A., Figueiredo, J. C., Thibodeau, S. N., Wadt, K., Therkildsen, C., Okkels, H., Ketabi, Z., Moreira, L., Sánchez, A., Serra-Burriel, M., Pineda, M., Navarro, M., Blanco, I., Green, K., Lalloo, F., Crosbie, E. J., Hill, J., Denton, O. G., Frayling, I. M., Rødland, E. A., Vasen, H., Mints, M., Neffa, F., Esperon, P., Alvarez, K., Kariv, R., Rosner, G., Pinero, T. A., Gonzalez, M. L., Kalfayan, P., Tjandra, D., Winship, I. M., Macrae, F., Möslein, G., Mecklin, J-P., Nielsen, M. & Møller, P., 24 Jul 2019, In : Genetics in medicine : official journal of the American College of Medical Genetics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2018
  4. Published

    Pediatric cancer families' participation in whole-genome sequencing research in Denmark: Parent perspectives

    Byrjalsen, A., Stoltze, U., Wadt, K., Hjalgrim, L. L., Gerdes, A-M., Schmiegelow, K. & Wahlberg, A., Nov 2018, In : European Journal of Cancer Care. 27, 6, p. e12877

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    En familie med nedarvet DICER1-mutation

    Altaraihi, M., Pedersen, J., Rossing, M., Gerdes, A-M. & Wadt, K., 18 Jun 2018, In : Ugeskrift for Laeger. 180, 24, p. V01180063

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Kræftdisponerende mutationer er hyppige hos børn og unge med kræft

    Stoltze, U. K., Byrjalsen, A., Hjalgrim, L. L., Wahlberg, A., Gupta, R., Gerdes, A-M., Wadt, K. & Schmiegelow, K., 23 Apr 2018, In : Ugeskrift for Laeger. 180, 17, p. V07170566

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Clinical characteristics and registry-validated extended pedigrees of germline TP53 mutation carriers in Denmark

    Stoltze, U., Skytte, A-B., Roed, H., Hasle, H., Ejlertsen, B., Overeem Hansen, T. V., Schmiegelow, K., Gerdes, A-M. & Wadt, K., 2018, In : P L o S One. 13, 1, p. e0190050

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide

    Walpole, S., Pritchard, A. L., Cebulla, C. M., Pilarski, R., Stautberg, M., Davidorf, F. H., de la Fouchardière, A., Cabaret, O., Golmard, L., Stoppa-Lyonnet, D., Garfield, E., Njauw, C-N., Cheung, M., Turunen, J. A., Repo, P., Järvinen, R-S., van Doorn, R., Jager, M. J., Luyten, G. P. M., Marinkovic, M., Chau, C., Potrony, M., Höiom, V., Helgadottir, H., Pastorino, L., Bruno, W., Andreotti, V., Dalmasso, B., Ciccarese, G., Queirolo, P., Mastracci, L., Wadt, K., Kiilgaard, J. F., Speicher, M. R., van Poppelen, N., Kilic, E., Al-Jamal, R. T., Dianzani, I., Betti, M., Bergmann, C., Santagata, S., Dahiya, S., Taibjee, S., Burke, J., Poplawski, N., O'Shea, S. J., Newton-Bishop, J., Adlard, J., Adams, D. J., Lane, A-M., Kim, I., Klebe, S., Racher, H., Harbour, J. W., Nickerson, M. L., Murali, R., Palmer, J. M., Howlie, M., Symmons, J., Hamilton, H., Warrier, S., Glasson, W., Johansson, P., Robles-Espinoza, C. D., Ossio, R., de Klein, A., Puig, S., Ghiorzo, P., Nielsen, M., Kivelä, T. T., Tsao, H., Testa, J. R., Gerami, P., Stern, M-H., Paillerets, B. B., Abdel-Rahman, M. H. & Hayward, N. K., 2018, In : Journal of the National Cancer Institute. 110, 12, p. 1328-1341 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published
  10. 2017
  11. Published

    Germline Variation at CDKN2A and Associations with Nevus Phenotypes among Members of Melanoma Families

    Taylor, N. J., Mitra, N., Goldstein, A. M., Tucker, M. A., Avril, M-F., Azizi, E., Bergman, W., Bishop, D. T., Bressac-de Paillerets, B., Bruno, W., Calista, D., Cannon-Albright, L. A., Cuellar, F., Cust, A. E., Demenais, F., Elder, D. E., Gerdes, A-M., Ghiorzo, P., Grazziotin, T. C., Hansson, J., Harland, M., Hayward, N. K., Hocevar, M., Höiom, V., Ingvar, C., Landi, M. T., Landman, G., Larre-Borges, A., Leachman, S. A., Mann, G. J., Nagore, E., Olsson, H., Palmer, J. M., Perić, B., Pjanova, D., Pritchard, A., Puig, S., van der Stoep, N., Wadt, K. A. W., Whitaker, L., Yang, X. R., Newton Bishop, J. A., Gruis, N. A., Kanetsky, P. A. & GenoMEL Study Group, Dec 2017, In : The Journal of investigative dermatology. 137, 12, p. 2606-2612 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published
  13. 2016
  14. Published

    Deep sequencing of uveal melanoma identifies a recurrent mutation in PLCB4

    Johansson, P., Aoude, L. G., Wadt, K., Glasson, W. J., Warrier, S. K., Hewitt, A. W., Kiilgaard, J. F., Heegaard, S., Isaacs, T., Franchina, M., Ingvar, C., Vermeulen, T., Whitehead, K. J., Schmidt, C. W., Palmer, J. M., Symmons, J., Gerdes, A-M., Jönsson, G. & Hayward, N. K., 14 Dec 2016, In : Oncotarget. 7, 4, p. 4624-31

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Phenotypic and histopathological tumor characteristics according to CDKN2A mutation status among affected members of melanoma families

    Taylor, N. J., Handorf, E. A., Mitra, N., Avril, M-F., Azizi, E., Bergman, W., Bianchi-Scarrà, G., Bishop, D. T., Bressac-de Paillerets, B., Calista, D., Cannon-Albright, L. A., Cuellar, F., Cust, A. E., Demenais, F., Elder, D. E., Friedman, E., Gerdes, A-M., Ghiorzo, P., Goldstein, A. M., Grazziotin, T. C., Hansson, J., Hayward, N. K., Hocevar, M., Höiom, V., Holland, E. A., Ingvar, C., Landi, M. T., Landman, G., Larre-Borges, A., Leachman, S. A., Mann, G. J., Nagore, E., Olsson, H., Palmer, J., Perić, B., Pjanova, D., Puig, S., Schmid, H., van der Stoep, N., Tucker, M. A., Wadt, K. A. W., Whitaker, L., Yang, X. R., Newton Bishop, J. A., Gruis, N. A., Kanetsky, P. A. & GenoMEL Consortium, 28 Jan 2016, In : The Journal of investigative dermatology. 136, 5, p. 1066–1069

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Germline TERT promoter mutations are rare in familial melanoma

    Harland, M., Petljak, M., Robles-Espinoza, C. D., Ding, Z., Gruis, N. A., van Doorn, R., Pooley, K. A., Dunning, A. M., Aoude, L. G., Wadt, K. A. W., Gerdes, A-M., Brown, K. M., Hayward, N. K., Newton-Bishop, J. A., Adams, D. J. & Bishop, D. T., 2016, In : Familial Cancer. 15, 1, p. 139-40

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2015
  18. Published

    High accuracy of family history of melanoma in Danish melanoma cases

    Wadt, K. A. W., Drzewiecki, K. T. & Gerdes, A-M., Dec 2015, In : Familial Cancer. 14, 4, p. 609-13 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    POLE mutations in families predisposed to cutaneous melanoma

    Aoude, L. G., Heitzer, E., Johansson, P., Gartside, M., Wadt, K., Pritchard, A. L., Palmer, J. M., Symmons, J., Gerdes, A-M., Montgomery, G. W., Martin, N. G., Tomlinson, I., Kearsey, S. & Hayward, N. K., Dec 2015, In : Familial Cancer. 14, 4, p. 621-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Melanoma genetics

    Read, J., Wadt, K. A. W. & Hayward, N. K., 3 Sep 2015, In : Journal of Medical Genetics. 53, 1, p. 1-14

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Germline RAD51B truncating mutation in a family with cutaneous melanoma

    Wadt, K. A. W., Aoude, L. G., Golmard, L., Hansen, T. V. O., Sastre-Garau, X., Hayward, N. K. & Gerdes, A-M., Jun 2015, In : Familial Cancer. 14, 2, p. 337-40 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Genetics of familial melanoma: 20 years after CDKN2A

    Aoude, L. G., Wadt, K. A. W., Pritchard, A. L. & Hayward, N. K., Mar 2015, In : Pigment Cell & Melanoma Research. 28, 2, p. 148-60 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma

    Aoude, L. G., Pritchard, A. L., Robles-Espinoza, C. D., Wadt, K., Harland, M., Choi, J., Gartside, M., Quesada, V., Johansson, P., Palmer, J. M., Ramsay, A. J., Zhang, X., Jones, K., Symmons, J., Holland, E. A., Schmid, H., Bonazzi, V., Woods, S., Dutton-Regester, K., Stark, M. S., Snowden, H., van Doorn, R., Montgomery, G. W., Martin, N. G., Keane, T. M., López-Otín, C., Gerdes, A-M., Olsson, H., Ingvar, C., Borg, A., Gruis, N. A., Trent, J. M., Jönsson, G., Bishop, D. T., Mann, G. J., Newton-Bishop, J. A., Brown, K. M., Adams, D. J. & Hayward, N. K., Feb 2015, In : National Cancer Institute. Journal (Online). 107, 2, p. dju408

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    A recurrent germline BAP1 mutation and extension of the BAP1 tumor predisposition spectrum to include basal cell carcinoma

    Wadt, K. A. W., Aoude, L. G., Johansson, P., Solinas, A., Pritchard, A., Crainic, O., Andersen, M. T., Kiilgaard, J. F., Heegaard, S., Sunde, L., Federspiel, B., Madore, J., Thompson, J. F., McCarthy, S. W., Goodwin, A., Tsao, H., Jönsson, G., Busam, K., Gupta, R., Trent, J. M., Gerdes, A-M., Brown, K. M., Scolyer, R. A. & Hayward, N. K., 2015, In : Clinical Genetics. 88, 3, p. 267-72

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Molecular characterization of melanoma cases in denmark suspected of genetic predisposition

    Wadt, K. A. W., Aoude, L. G., Krogh, L., Sunde, L., Bojesen, A., Grønskov, K., Wartacz, N., Ek, J., Andersen, M. T., Andersen, M. K., Borg, Å., Heegaard, S., Kiilgaard, J. F., Hansen, T. V. O., Klein, K., Jönsson, G., Drzewiecki, K. T., Dunø, M., Hayward, N. K. & Gerdes, A-M., 2015, In : P L o S One. 10, 3, p. e0122662

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Molecular genetic characterisation of high-risk melanoma cases in Denmark

    Wadt, K., 2015, 138 p.

    Research output: Book/ReportPh.D. thesisResearch

  27. 2014
  28. Published

    CDKN2A-mutation hos en familie med arveligt malignt melanom

    Djursby, M., Wadt, K., Lorentzen, H., Borg, A., Gerdes, A-M. & Krogh, L., 29 Sep 2014, In : Ugeskrift for læger [online]. 176, 40

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published
  30. 2013
  31. Published

    A BAP1 mutation in a Danish family predisposes to uveal melanoma and other cancers

    Aoude, L. G., Wadt, K., Bojesen, A., Crüger, D. G., Borg, A., Trent, J. M., Brown, K. M., Gerdes, A-M., Jönsson, G. & Hayward, N. K., 2013, In : P L o S One. 8, 8, p. e72144

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2012
  33. Published

    A cryptic BAP1 splice mutation in a family with uveal and cutaneous melanoma, and paraganglioma

    Wadt, K., Choi, J., Chung, J-Y., Kiilgaard, J. F., Heegaard, S., Drzewiecki, K. T., Trent, J. M., Hewitt, S. M., Hayward, N. K., Gerdes, A-M. & Brown, K. M., 2012, In : Pigment Cell & Melanoma Research. 25, 6, p. 815-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Fetal ventriculomegaly due to familial submicroscopic terminal 6q deletions

    Wadt, K., Jensen, L. N., Bjerglund, L., Lundstrøm, M. S., Kirchhoff, E. M. & Kjaergaard, S., 2012, In : Prenatal Diagnosis. 32, 12, p. 1212-1217 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Genetiske fund giver nye muligheder for udredning af arveligt malignt melanom

    Wadt, K., Drzewiecki, K. T. & Gerdes, A-M. A., 2012, In : Ugeskrift for Laeger. 174, 8, p. 493-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Novel germline c-MET mutation in a family with hereditary papillary renal carcinoma

    Wadt, K., Gerdes, A-M., Hansen, T. V. O., Toft, B. G., Friis-Hansen, L. & Andersen, M. K., 2012, In : Familial Cancer. 11, 3, p. 535-7 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Ny genteknologisk diagnostik af familiær gastrointestinal stromal tumor

    Wadt, K., Andersen, M. K., Hansen, T. V. O. & Gerdes, A-M., 2012, In : Ugeskrift for Laeger. 174, 21, p. 1462-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. 1998
  39. Ciliary neurotrophic factor potentiates the beta-cell inhibitory effect of IL-1beta in rat pancreatic islets associated with increased nitric oxide synthesis and increased expression of inducible nitric oxide synthase

    Wadt, K. A., Larsen, C. M., Andersen, H. U., Nielsen, K., Karlsen, A. E. & Mandrup-Poulsen, T., Oct 1998, In : Diabetes. 47, 10, p. 1602-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases

    Larsen, C. M., Wadt, K. A., Juhl, L. F., Andersen, H. U., Karlsen, A. E., Su, M. S., Seedorf, K., Shapiro, L., Dinarello, C. A. & Mandrup-Poulsen, T., 12 Jun 1998, In : The journal of biological chemistry. 273, 24, p. 15294-300 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 45088683