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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2019
  2. Published

    Genome-wide cell-free DNA fragmentation in patients with cancer

    Cristiano, S., Leal, A., Phallen, J., Fiksel, J., Adleff, V., Bruhm, D. C., Jensen, S. Ø., Medina, J. E., Hruban, C., White, J. R., Palsgrove, D. N., Niknafs, N., Anagnostou, V., Forde, P., Naidoo, J., Marrone, K., Brahmer, J., Woodward, B. D., Husain, H., van Rooijen, K. L., Ørntoft, M-B. W., Madsen, A. H., van de Velde, C. J. H., Verheij, M., Cats, A., Punt, C. J. A., Vink, G. R., van Grieken, N. C. T., Koopman, M., Fijneman, R. J. A., Johansen, J. S., Nielsen, H. J., Meijer, G. A., Andersen, C. L., Scharpf, R. B. & Velculescu, V. E., Jun 2019, In : Nature. 570, 7761, p. 385-389 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  3. E-pub ahead of print

    Germline BRCA2 K3326X and CHEK2 I157T mutations increase risk for sporadic pancreatic ductal adenocarcinoma

    Obazee, O., Archibugi, L., Andriulli, A., Soucek, P., Małecka-Panas, E., Ivanauskas, A., Johnson, T., Gazouli, M., Pausch, T., Lawlor, R. T., Cavestro, G. M., Milanetto, A. C., Di Leo, M., Pasquali, C., Hegyi, P., Szentesi, A., Radu, C. E., Gheorghe, C., Theodoropoulos, G. E., Bergmann, F., Brenner, H., Vodickova, L., Katzke, V., Campa, D., Strobel, O., Kaiser, J., Pezzilli, R., Federici, F., Mohelnikova-Duchonova, B., Boggi, U., Lemstrova, R., Johansen, J. S., Bojesen, S. E., Chen, I., Jensen, B. V., Capurso, G., Pazienza, V., Dervenis, C., Sperti, C., Mambrini, A., Hackert, T., Kaaks, R., Basso, D., Talar-Wojnarowska, R., Maiello, E., Izbicki, J. R., Cuk, K., Saum, K. U., Cantore, M., Kupcinskas, J., Palmieri, O., Delle Fave, G., Landi, S., Salvia, R., Fogar, P., Vashist, Y. K., Scarpa, A., Vodicka, P., Tjaden, C., Iskierka-Jazdzewska, E. & Canzian, F., 23 Jan 2019, In : International Journal of Cancer.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Increased serological, cancer-associated protein biomarker levels at diagnosis of large bowel adenoma: Risk of subsequent primary malignancy?

    Piper, T. B., Jørgensen, L. N., Olsen, J., Nielsen, K. T., Davis, G., Johansen, J. S., Jarle Christensen, I. & Nielsen, H. J., 2019, In : Acta Oncologica. 58, sup1: Advanced Adenomas of the Colon and Rectum, p. S42-S48 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2018
  6. Published

    Methodological development and biological observations of cell free DNA with a simple direct fluorescent assay in colorectal cancer

    Boysen, A. K., Sørensen, B. S., Lefevre, A. C., Abrantes, R., Johansen, J. S., Jensen, B. V., Schou, J. V., Larsen, F. O., Nielsen, D., Taflin, H., Gustavson, B., Wettergren, Y., Sorensen, B. S., Ree, A. H., Dueland, S., Pallisgaard, N. & Spindler, K. L., Dec 2018, In : Clinica chimica acta; international journal of clinical chemistry. 487, p. 107-111 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published
  8. Published

    Total cell-free DNA, carcinoembryonic antigen, and C-reactive protein for assessment of prognosis in patients with metastatic colorectal cancer

    Spindler, K-L. G., Demuth, C., Sorensen, B. S., Johansen, J. S., Nielsen, D., Pallisgaard, N., Hoegdall, E., Pfeiffer, P. & Vittrup Jensen, B., Nov 2018, In : Tumor Biology. 40, 11, p. 1010428318811207

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Serum Biomarker Signature-Based Liquid Biopsy for Diagnosis of Early-Stage Pancreatic Cancer

    Mellby, L. D., Nyberg, A. P., Johansen, J. S., Wingren, C., Nordestgaard, B. G., Bojesen, S. E., Mitchell, B. L., Sheppard, B. C., Sears, R. C. & Borrebaeck, C. A. K., 1 Oct 2018, In : Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 36, 28, p. 2887-2894 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Measuring KRAS Mutations in Circulating Tumor DNA by Droplet Digital PCR and Next-Generation Sequencing

    Demuth, C., Spindler, K-L. G., Johansen, J. S., Pallisgaard, N., Nielsen, D., Hogdall, E., Vittrup, B. & Sorensen, B. S., Oct 2018, In : Translational Oncology. 11, 5, p. 1220-1224 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Drug concentrations and anti-drug antibodies during treatment with biosimilar infliximab (CT-P13) in routine care

    Glintborg, B., Kringelbach, T., Bolstad, N., Warren, D. J., Eng, G., Sørensen, I. J., Loft, A. G., Hendricks, O., Hansen, I., Linauskas, A., Nordin, H., Kristensen, S., Lindegaard, H., Jensen, D. V., Goll, G. L., Høgdall, E., Gehin, J., Enevold, C., Nielsen, C. H., Krogh, N. S., Johansen, J. S. & Hetland, M. L., Sep 2018, In : Scandinavian Journal of Rheumatology. 47, 5, p. 418-421 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  12. Published

    Systematic literature review of IL-6 as a biomarker or treatment target in patients with gastric, bile duct, pancreatic and colorectal cancer

    Vainer, N., Dehlendorff, C. & Johansen, J. S., 3 Jul 2018, In : Oncotarget. 9, 51, p. 29820-29841 22 p.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Circulating serum interleukin-6, serum chitinase-3-like protein-1, and plasma vascular endothelial growth factor are not predictive for remission and radiographic progression in patients with early rheumatoid arthritis: post-hoc explorative and validation studies based on the CIMESTRA and OPERA trials

    Brahe, C. H., Dehlendorff, C., Østergaard, M., Johansen, J. S., Ørnbjerg, L. M., Hørslev-Petersen, K., Stengaard-Pedersen, K., Junker, P., Ellingsen, T., Lindegaard, H., Hansen, I., Lottenburger, T., Jacobsen, S., Jurik, A. G. & Hetland, M. L., Jul 2018, In : Scandinavian Journal of Rheumatology. 47, 4, p. 259-269 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Prognostic role of carcinoembryonic antigen and carbohydrate antigen 19-9 in metastatic colorectal cancer: a BRAF-mutant subset with high CA 19-9 level and poor outcome

    Thomsen, M., Skovlund, E., Sorbye, H., Bolstad, N., Nustad, K. J., Glimelius, B., Pfeiffer, P., Kure, E. H., Johansen, J. S., Tveit, K. M., Christoffersen, T. & Guren, T. K., Jun 2018, In : British Journal of Cancer. 118, 12, p. 1609-1616 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Circulating cell-free DNA as predictor of treatment failure after neoadjuvant chemo-radiotherapy before surgery in patients with locally advanced rectal cancer

    Schou, J. V., Larsen, F. O., Sørensen, B. S., Abrantes, R., Boysen, A. K., Johansen, J. S., Jensen, B. V., Nielsen, D. L. & Spindler, K. L., 1 Mar 2018, In : Annals of Oncology. 29, 3, p. 610-615 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published
  17. Published

    Plasma YKL-40 as a biomarker for bevacizumab efficacy in patients with newly diagnosed glioblastoma in the phase 3 randomized AVAglio trial

    Boisen, M. K., Holst, C. B., Consalvo, N., Chinot, O. L. & Johansen, J. S., 23 Jan 2018, In : Oncotarget. 9, 6, p. 6752-6762 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Plasma MicroRNA Profiles in Patients with Early Rheumatoid Arthritis Responding to Adalimumab plus Methotrexate vs Methotrexate Alone: A Placebo-controlled Clinical Trial

    Sode, J., Krintel, S. B., Carlsen, A. L., Hetland, M. L., Johansen, J. S., Hørslev-Petersen, K., Stengaard-Pedersen, K., Ellingsen, T., Burton, M., Junker, P., Østergaard, M. & Heegaard, N. H. H., Jan 2018, In : Journal of Rheumatology. 45, 1, p. 53-61 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published
  20. Published

    Is 14.3.3ɳ a Predictor of Development of Rheumatoid Arthritis in Patients with Early Undifferentiated Arthritis?

    Carlsen, K. M., Schmidt, N., Duer, A., Hørslev-Petersen, K., Brahe, C. C. H., Hetland, M. L., Biln, N. K., Zaharik, M. L., Ejbjerg, B. J., Bak, L., Hansen, M. S., Johansen, J. S., Lindegaard, H. M., Møller, J. M. & Østergaard, M., 2018, In : Arthritis & Rheumatology. 70, S9, 3 p., 1482.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  21. Published

    Stromal Content Is Correlated With Tissue Site, Contrast Retention, and Survival in Pancreatic Adenocarcinoma

    Torphy, R. J., Wang, Z., True-Yasaki, A., Volmar, K. E., Rashid, N., Yeh, B., Anderson, J. M., Johansen, J. S., Hollingsworth, M. A., Yeh, J. J. & Collisson, E. A., 2018, In : JCO precision oncology. 2018

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published
  23. 2017
  24. Published

    Ultrasensitive plasma ctDNA KRAS assay for detection, prognosis, and assessment of therapeutic response in patients with unresectable pancreatic ductal adenocarcinoma

    Chen, I., Raymond, V. M., Geis, J. A., Collisson, E. A., Jensen, B. V., Hermann, K. L., Erlander, M. G., Tempero, M. & Johansen, J. S., 26 Oct 2017, In : Oncotarget. 8, 58, p. 97769-97786 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Cell-Free DNA in Metastatic Colorectal Cancer: A Systematic Review and Meta-Analysis

    Spindler, K-L. G., Boysen, A. K., Pallisgård, N., Johansen, J. S., Tabernero, J., Sørensen, M. M., Jensen, B. V., Hansen, T. F., Sefrioui, D., Andersen, R. F., Brandslund, I. & Jakobsen, A., Sep 2017, In : The oncologist. 22, 9, p. 1049-1055 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Health-related quality of life in patients with metastatic colorectal cancer, association with systemic inflammatory response and RAS and BRAF mutation status

    Thomsen, M., Guren, M. G., Skovlund, E., Glimelius, B., Hjermstad, M. J., Johansen, J. S., Kure, E., Sorbye, H., Pfeiffer, P., Christoffersen, T., Guren, T. K. & Tveit, K. M., Aug 2017, In : European journal of cancer (Oxford, England : 1990). 81, p. 26-35 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published
  28. Published

    Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC

    Strell, C., Norberg, K. J., Mezheyeuski, A., Schnittert, J., Kuninty, P. R., Moro, C. F., Paulsson, J., Schultz, N. A., Calatayud, D., Löhr, J. M., Frings, O., Verbeke, C. S., Heuchel, R. L., Prakash, J., Johansen, J. S. & Östman, A., 2017, In : B J C. 117, 1, p. 65-77

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published
  30. 2016
  31. Published
  32. Published

    Interleukin-6 and C-reactive protein as prognostic biomarkers in metastatic colorectal cancer

    Thomsen, M., Kersten, C., Sorbye, H., Skovlund, E., Glimelius, B., Pfeiffer, P., Johansen, J. S., Kure, E. H., Ikdahl, T., Tveit, K. M., Christoffersen, T. & Guren, T. K., 15 Nov 2016, In : Oncotarget. 7, 46, p. 75013-75022 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published
  34. Published

    Serum YKL-40 and gestational diabetes - an observational cohort study

    Gybel-Brask, D., Johansen, J. S., Christiansen, I. J., Skibsted, L. & Høgdall, E. V. S., Sep 2016, In : APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 124, 9, p. 770-775

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Prognostic and predictive value of YKL-40 in stage IIB-III melanoma

    Krogh, M., Christensen, I., Bouwhuis, M., Johansen, J. S., Nørgaard, P., Schmidt, H., Hansson, J., Suciu, S., Eggermont, A. M. M., Bastholt, L. & Nordic Melanoma Group and EORTC Melanoma Group, Aug 2016, In : Melanoma Research. 26, 4, p. 367-76 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    YKL-40 in allogeneic hematopoietic cell transplantation after AML and myelodysplastic syndrome

    Kornblit, B., Wang, T., Lee, S. J., Spellman, S. R., Zhu, X., Fleischhauer, K., Müller, C., Verneris, M. R., Müller, K., Johansen, J. S., Vindelov, L. & Garred, P., 18 Jul 2016, In : Bone Marrow Transplantation. 51, 12, p. 1556-1560 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Increased serological cancer-associated biomarker levels at large bowel endoscopy and risk of subsequent primary cancer (†)

    Hvolris, M. H., Piper, T. B., Hammer, E., Jørgensen, L. N., Olsen, J., Rahr, H. B., Nielsen, K. T., Laurberg, S., Christensen, I. J., Brünner, N., Johansen, J. S., Davis, G. J., Dowell, B. L. & Nielsen, H. J., Jul 2016, In : Scandinavian Journal of Gastroenterology. 51, 7, p. 860-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

    Laklai, H., Miroshnikova, Y. A., Pickup, M. W., Collisson, E. A., Kim, G. E., Barrett, A. S., Hill, R. C., Lakins, J. N., Schlaepfer, D. D., Mouw, J. K., LeBleu, V. S., Roy, N., Novitskiy, S. V., Johansen, J. S., Poli, V., Kalluri, R., Iacobuzio-Donahue, C. A., Wood, L. D., Hebrok, M., Hansen, K., Moses, H. L. & Weaver, V. M., May 2016, In : Nature Medicine. 22, 5, p. 497-505 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published
  40. Published

    Changes in Multi-Biomarker Disease Activity (MBDA) Score Correlate with Changes in Established Disease Activity Measurements in Patients with Early Ra from The Opera Study

    Brahe, C. C. H., Østergaard, M., Johansen, J. S., Defranoux, N., Hwang, C-C., Bolce, R., Sasso, E., Hørslev-Petersen, K., Steengaard-Pedersen, K., Junker, P., Ellingsen, T., Ahlquist, P., Lindegaard, H., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Ammitzbøll, C., Jørgensen, A., Krintel, S. B., Raun, J. & Hetland, M. L., 2016, In : Annals of the Rheumatic Diseases. 75, Suppl. 2, p. 450 1 p., FRI0067.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  41. Published

    Clinical and radiographic outcome of a treat-to-target strategy using methotrexate and intra-articular glucocorticoids with or without adalimumab induction: a 2-year investigator-initiated, double-blinded, randomised, controlled trial (OPERA)

    Hørslev-Petersen, K., Hetland, M. L., Ørnbjerg, L. M., Junker, P., Pødenphanth, J., Ellingsen, T., Ahlquist, P., Lindegaard, H., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Ammitzbøll, C. G., Jørgensen, A., Krintel, S. B., Raun, J., Johansen, J. S., Østergaard, M., Stengaard-Pedersen, K., OPERA Study-Group, Slot, O., Skjødt, H., Manilo, N. & Bliddal, H., 2016, In : Annals of the Rheumatic Diseases. 75, 9, p. 1645-53 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published
  43. Published

    Multi-Biomarker Disease Activity (MBDA) Score and Prediction of Radiographic Progression in a Randomized Study of Patients with Early RA Treated with m methotrexate Alone or with Adalimumab

    Brahe, C. C. H., Østergaard, M., Johansen, J. S., Defranoux, N. A., Hwang, C. C., Wang, X., Bolce, R. J., Sasso, E. H., Hørslev-Petersen, K., Stengaard-Pedersen, K., Ørnbjerg, L. M., Junker, P., Ellingsen, T., Ahlquist, P., Lindegaard, H., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I. T., Lottenburger, T., Ammitzbøll, C. G., Jørgensen, A., Krintel, S. B., Raun, J. L. & Hetland, M. L., 2016, In : Arthritis & Rheumatology. 68, S10, 2520.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  44. Published

    Non-Medical Switch from Originator To Biosimilar Infliximab among Patients with Inflammatory Rheumatic Disease – Impact on S-Infliximab and Antidrug-Antibodies. Results from The National Danish Rheumatologic Biobank and The Danbio Registry

    Glintborg, B., Kringelbach, T. M., Høgdall, E., Sørensen, I. J., Jensen, D. V., Loft, A. G., Hendricks, O., Jensen Hansen, I. M., Bolstad, N., Grøn, K. L., Eng, G., Enevold, C., Nielsen, C. H., Warren, D., Goll, G., Gehin, J., Johansen, J. S. & Hetland, M. L., 2016, In : Annals of the Rheumatic Diseases. 75, Suppl. 2, p. 224 1 p., THU0123.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  45. Published

    Non-Medical Switch from Originator to Biosimilar Infliximab in Patients with Inflammatory Arthritis – Impact on s-Infliximab and Antidrug-Antibodies. Results from the Danish Rheumatologic Biobank and the Danbio Registry

    Glintborg, B., Kringelbach, T. M., Høgdall, E., Sørensen, I. J., Jensen, D. V., Loft, A. G., Hendricks, O., Hansen, I. M. J., Linauskas, A., Kristensen, S., Lindegaard, H., Nordin, H., Bolstad, N., Warren, D., Warren, D., Gehin, J., Goll, G. L., Grøn, K. L., Eng, G. P., Enevold, C., Nielsen, C. H., Johansen, J. S. & Hetland, M. L., 2016, In : Arthritis & Rheumatology. 68, S10, 1997.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  46. Published

    Prediction of treatment response to adalimumab: a double-blind placebo-controlled study of circulating microRNA in patients with early rheumatoid arthritis

    Krintel, S. B., Dehlendorff, C., Hetland, M. L., Hørslev-Petersen, K., Andersen, K. K., Junker, P., Pødenphanth, J., Ellingsen, T., Ahlquist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Horn, H. C., Jørgensen, A., Raun, J., Ammitzbøll, C. G., Østergaard, M., Stengaard-Pedersen, K. & Johansen, J. S., 2016, In : The pharmacogenomics journal. 16, 2, p. 141-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published
  48. Published

    The Potential Diagnostic Value of Serum microRNA Signature in Patients with Pancreatic Cancer

    Johansen, J. S., Calatayud, D., Albieri, V., Schultz, N. A., Dehlendorff, C., Werner, J., Jensen, B. V., Pfeiffer, P., Bojesen, S. E., Giese, N., Nielsen, K. R., Nielsen, S. E., Yilmaz, M., Holländer, N. H. & Andersen, K. K., 2016, In : International Journal of Cancer. 139, 10, p. 2312-24

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2015
  50. Published
  51. Published

    Clinical utility of KRAS status in circulating plasma DNA compared to archival tumour tissue from patients with metastatic colorectal cancer treated with anti-epidermal growth factor receptor therapy

    Spindler, K-L. G., Pallisgaard, N., Appelt, A. L., Andersen, R. F., Schou, J. V., Nielsen, D., Pfeiffer, P., Yilmaz, M., Johansen, J. S., Hoegdall, E. V., Jakobsen, A. & Jensen, B. V., Nov 2015, In : European journal of cancer (Oxford, England : 1990). 51, 17, p. 2678-85 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    YKL-40 and genetic status of CHI3L1 in a large group of asthmatics

    Hansen, J. W., Thomsen, S. F., Porsbjerg, C., Rasmussen, L. M., Harmsen, L., Johansen, J. S. & Backer, V., 16 Sep 2015, In : European Clinical Respiratory Journal. 2, 25117, p. 25117

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published
  54. Published

    Serum YKL-40: a new independent prognostic marker for skeletal complications in patients with multiple myeloma

    Mylin, A. K., Abildgaard, N., Johansen, J. S., Heickendorff, L., Kreiner, S., Waage, A., Turesson, I., Gimsing, P. & for the Nordic Myeloma Study Group, 11 Feb 2015, In : Leukemia and Lymphoma. 56, 9, p. 2650-59 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published
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