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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Curriculum

Senior Scientist, Associate Professor

Current position:

-Senior Scientist, Copenhagen Hepatitis C Program (CO-HEP) at Copenhagen University Hospital, Hvidovre

-Associate Professor in Experimental Control of Hepatitis C Virus, Faculty of Health and Medical Sciences at University of Copenhagen

Scientific focus areas:

In vitro studies of hepatitis C virus sensitivity and resistance to antivirals.

Hepatitis C virus vaccine development.

Development of hepatitis C virus cell culture systems.

Education:

2001                            Doctoral degree (Dr. med.) at Ruprecht-Karls-University Heidelberg

1994-2001                   Studies of Medicine, MD, Ruprecht-Karls-University Heidelberg                                         Fellowship of the German National Academic Foundation

Practical Professional Education:

09/2005 - present        Senior scientist, CO-HEP, Copenhagen University Hospital, Hvidovre, Copenhagen,     Denmark.

11/2004 - 08/2005       Research and Clinical Associate, Department of Internal Medicin,                                    University Hospital Bonn, Germany.

02/2003 - 08/2004       Clinical Associate, Department of Internal Medicine, Spital Limmattal                                   Zurich, Switzerland.

01/2002 - 01/2003       Research Associate, Department of Neuropathology, University Hospital                                   Zurich, Switzerland.        .

09/1997- 10/1998        Research fellowship at the Department of Pathology, Case Western                                   Reserve University, Cleveland, USA.

Contact: judith@gottwein.eu

 

Expertises

HCV virology; HCV cell culture development; Study of antiviral compounds; HCV vaccine development; Cell culture; Molecular biology; Medicine

Main research areas

Main research areas are studies of resistance of HCV to antivirals and HCV vaccine development with focus on whole virus inactivated and virus like particle vaccine candidates.

Current research

We are characterizing the efficacy of antivirals and combinations of antivirals against different HCV variants. We further study HCV resistance to antivirals including identification of resistance associated substitutions and mechanisms of resistance development.

We investigate development of HCV vaccine candidates. We are establishing a bioprocess for development of whole viral particle inactivated vaccine candidates. We are testing such vaccine candidates and vaccine candidates based on virus like particles.

Potential conflicts of interest

none

ID: 173884