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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2019
  2. Published

    Populations, decreasing fertility, and reproductive health

    Skakkebaek, N. E., Jørgensen, N., Andersson, A-M., Juul, A., Main, K. M., Jensen, T. K. & Toppari, J., 13 Apr 2019, In : Lancet (London, England). 393, 10180, p. 1500-1501 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Low-saturated-fat and low-cholesterol diet does not alter pubertal development and hormonal status in adolescents

    Sadov, S., Virtanen, H. E., Main, K. M., Andersson, A-M., Juul, A., Jula, A., Raitakari, O. T., Pahkala, K., Niinikoski, H. & Toppari, J., Feb 2019, In : Acta paediatrica. 108, 2, p. 321-327 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Cord-Blood Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes

    Lamichhane, S., Ahonen, L., Dyrlund, T. S., Dickens, A. M., Siljander, H., Hyöty, H., Ilonen, J., Toppari, J., Veijola, R., Hyötyläinen, T., Knip, M. & Oresic, M., 21 Jan 2019, In : Biomolecules. 9, 1, 9 p., 33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    An update on semen quality among young Finnish men and comparison with Danish data

    Rodprasert, W., Virtanen, H. E., Sadov, S., Perheentupa, A., Skakkebaek, N. E., Jørgensen, N. & Toppari, J., 1 Jan 2019, In : Andrology. 7, 1, p. 15-23 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2018
  7. Published

    A longitudinal plasma lipidomics dataset from children who developed islet autoimmunity and type 1 diabetes

    Lamichhane, S., Ahonen, L., Dyrlund, T. S., Siljander, H., Hyöty, H., Ilonen, J., Toppari, J., Veijola, R., Hyötyläinen, T., Knip, M. & Orešič, M., 13 Nov 2018, In : Scientific Data. 5, p. 180250

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes - Type 1 Diabetes Prediction and Prevention Study (DIPP)

    Lamichhane, S., Ahonen, L., Dyrlund, T. S., Kemppainen, E., Siljander, H., Hyöty, H., Ilonen, J., Toppari, J., Veijola, R., Hyötyläinen, T., Knip, M. & Oresic, M., 13 Jul 2018, In : Scientific Reports. 8, 1, p. 10635

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Association of In Utero Persistent Organic Pollutant Exposure with Placental Thyroid Hormones

    Li, Z-M., Hernandez-Moreno, D., Main, K. M., Skakkebæk, N. E., Kiviranta, H., Toppari, J., Feldt-Rasmussen, U., Shen, H., Schramm, K-W. & De Angelis, M., 2018, In : Endocrinology. 159, 10, p. 3473-3481

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Determination of thyroid hormones in placenta using isotope-dilution liquid chromatography quadrupole time-of-flight mass spectrometry

    Li, Z-M., Giesert, F., Vogt-Weisenhorn, D., Main, K. M., Skakkebæk, N. E., Kiviranta, H., Toppari, J., Feldt-Rasmussen, U., Shen, H., Schramm, K-W. & De Angelis, M., 2018, In : Journal of Chromatography. 1534, p. 85-92

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Postnatal Changes in Testicular Position are Associated with IGF-I and Function of Sertoli and Leydig Cells

    Koskenniemi, J. J., Virtanen, H. E., Wohlfahrt-Veje, C., Löyttyniemi, E., Skakkebaek, N. E., Juul, A., Andersson, A-M., Main, K. M. & Toppari, J., 2018, In : The Journal of clinical endocrinology and metabolism. 103, 4, p. 1429-1437

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2017
  13. Published
  14. Published

    Semen quality in the 21(st) century

    Virtanen, H. E., Jørgensen, N. & Toppari, J., Feb 2017, In : Nature reviews. Urology. 14, 2, p. 120-130 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Maternal use of mild analgesics during pregnancy associated with reduced anogenital distance in sons: a cohort study of 1027 mother-child pairs

    Lind, D. V., Main, K. M., Kyhl, H. B., Kristensen, D. M., Toppari, J., Andersen, H. R., Andersen, M. S., Skakkebæk, N. E. & Jensen, T. K., Jan 2017, In : Human reproduction (Oxford, England). 32, 1, p. 223-231 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2016
  17. Country-specific chemical signatures of persistent organic pollutants (POPs) in breast milk of French, Danish and Finnish women

    Antignac, J. P., Main, K. M., Virtanen, H. E., Boquien, C. Y., Marchand, P., Venisseau, A., Guiffard, I., Bichon, E., Wohlfahrt-Veje, C., Legrand, A., Boscher, C., Skakkebæk, N. E., Toppari, J. & Le Bizec, B., 9 Aug 2016, In : Environmental pollution (Barking, Essex : 1987).

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries

    Damsgaard, J., Joensen, U. N., Carlsen, E., Erenpreiss, J., Blomberg Jensen, M., Matulevicius, V., Zilaitiene, B., Olesen, I. A., Perheentupa, A., Punab, M., Salzbrunn, A., Toppari, J., Virtanen, H. E., Juul, A., Skakkebæk, N. E. & Jørgensen, N., 13 Jul 2016, In : European Urology. 70, 6, p. 1019-1029

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Compensated reduction in Leydig cell function is associated with lower semen quality variables: a study of 8182 European young men

    Jørgensen, N., Joensen, U. N., Toppari, J., Punab, M., Erenpreiss, J., Zilaitiene, B., Paasch, U., Salzbrunn, A., Fernandez, M. F., Virtanen, H. E., Matulevicius, V., Olea, N., Jensen, T. K., Petersen, J. H., Skakkebæk, N. E. & Andersson, A-M., May 2016, In : Human reproduction (Oxford, England). 31, 5, p. 947-57 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    TESTICULAR GROWTH DURING PUBERTY IN BOYS WITH AND WITHOUT A HISTORY OF CONGENITAL CRYPTORCHIDISM

    Sadov, S., Koskenniemi, J. J., Virtanen, H. E., Perheentupa, A., Petersen, J. H., Skakkebaek, N. E., Main, K. M. & Toppari, J., 6 Apr 2016, In : The Journal of clinical endocrinology and metabolism. 101, 6, p. 2570-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Semen quality improves marginally during young adulthood: a longitudinal follow-up study

    Perheentupa, A., Sadov, S., Rönkä, R., Virtanen, H. E., Rodprasert, W., Vierula, M., Jørgensen, N., Skakkebæk, N. E. & Toppari, J., Mar 2016, In : Human reproduction (Oxford, England). 31, 3, p. 502-10 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility

    Skakkebaek, N. E., Rajpert-De Meyts, E., Buck Louis, G. M., Toppari, J., Andersson, A-M., Eisenberg, M. L., Jensen, T. K., Jørgensen, N., Swan, S. H., Sapra, K. J., Ziebe, S., Priskorn, L. & Juul, A., Jan 2016, In : Physiological Reviews. 96, 1, p. 55-97 43 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2015
  24. Published

    Manufacturing doubt about endocrine disrupter science - A rebuttal of industry-sponsored critical comments on the UNEP/WHO report "State of the Science of Endocrine Disrupting Chemicals 2012"

    Bergman, Å., Becher, G., Blumberg, B., Bjerregaard, P., Bornman, R., Brandt, I., Casey, S. C., Frouin, H., Giudice, L. C., Heindel, J. J., Iguchi, T., Jobling, S., Kidd, K. A., Kortenkamp, A., Lind, P. M., Muir, D., Ochieng, R., Ropstad, E., Ross, P. S., Skakkebaek, N. E., Toppari, J., Vandenberg, L. N., Woodruff, T. J. & Zoeller, R. T., Dec 2015, In : Regulatory toxicology and pharmacology : RTP. 73, 3, p. 1007-17 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Male Reproductive Disorders, Diseases, and Costs of Exposure to Endocrine-Disrupting Chemicals in the European Union

    Hauser, R., Skakkebaek, N. E., Hass, U., Toppari, J., Juul, A., Andersson, A-M., Kortenkamp, A., Heindel, J. J. & Trasande, L., 5 Mar 2015, In : The Journal of clinical endocrinology and metabolism. 100, 4, p. 1267-77

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Association between levels of persistent organic pollutants in adipose tissue and cryptorchidism in early childhood: a case-control study

    Koskenniemi, J. J., Virtanen, H. E., Kiviranta, H., Damgaard, I. N., Matomäki, J., Thorup, J. M., Hurme, T., Skakkebaek, N. E., Main, K. M. & Toppari, J., 2015, In : Environmental Health: A Global Access Science Source. 14, p. 78

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2014
  28. Published

    Alcohol and male reproductive health: a cross-sectional study of 8344 healthy men from Europe and the USA

    Jensen, T. K., Swan, S., Jørgensen, N., Toppari, J., Redmon, B., Punab, M., Drobnis, E. Z., Haugen, T. B., Zilaitiene, B., Sparks, A. E., Irvine, D. S., Wang, C., Jouannet, P., Brazil, C., Paasch, U., Salzbrunn, A., Skakkebæk, N. E. & Andersson, A-M., Aug 2014, In : Human reproduction (Oxford, England). 29, 8, p. 1801-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Possible fetal determinants of male infertility

    Juul, A., Almstrup, K., Andersson, A-M., Jensen, T. K., Jørgensen, N., Main, K. M., Meyts, E. R-D., Toppari, J. & Skakkebæk, N. E., 17 Jun 2014, In : Nature reviews. Endocrinology. 10, p. 553-562

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    A path forward in the debate over health impacts of endocrine disrupting chemicals

    Zoeller, R. T., Bergman, Å., Becher, G., Bjerregaard, P., Bornman, R., Brandt, I., Iguchi, T., Jobling, S., Kidd, K. A., Kortenkamp, A., Skakkebaek, N. E., Toppari, J. & Vandenberg, L. N., 2014, In : Environmental Health: A Global Access Science Source. 14, 1, p. 118

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Association of placenta organotin concentrations with growth and ponderal index in 110 newborn boys from Finland during the first 18 months of life: a cohort study

    Rantakokko, P., Main, K. M., Wohlfart-Veje, C., Kiviranta, H., Airaksinen, R., Vartiainen, T., Skakkebæk, N. E., Toppari, J. & Virtanen, H. E., 2014, In : Environmental Health: A Global Access Science Source. 13, 1, p. 45

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Special issue on the Impact of endocrine disrupters on reproductive health

    Andersson, A-M., Frederiksen, H., Grigor, K. M., Toppari, J. & Skakkebæk, N. E., 2014, In : Reproduction (Cambridge, England). 147, 4, p. E1

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. 2013
  34. Published

    Characterization of the testicular, epididymal and endocrine phenotypes in the Leuven Vdr-deficient mouse model: targeting estrogen signalling

    Blomberg Jensen, M., Lieben, L., Nielsen, J. E., Willems, A., Jørgensen, A., Juul, A., Toppari, J., Carmeliet, G. & Rajpert-De Meyts, E., 5 Sep 2013, In : Molecular and Cellular Endocrinology. 377, 1-2, p. 93-102 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Science and policy on endocrine disrupters must not be mixed: a reply to a "common sense" intervention by toxicology journal editors

    Bergman, Å., Andersson, A-M., Becher, G., van den Berg, M., Blumberg, B., Bjerregaard, P., Bornehag, C-G., Bornman, R., Brandt, I., Brian, J. V., Casey, S. C., Fowler, P. A., Frouin, H., Giudice, L. C., Iguchi, T., Hass, U., Jobling, S., Juul, A., Kidd, K. A., Kortenkamp, A., Lind, M., Martin, O. V., Muir, D., Ochieng, R., Olea, N., Norrgren, L., Ropstad, E., Ross, P. S., Rudén, C., Scheringer, M., Skakkebaek, N. E., Söder, O., Sonnenschein, C., Soto, A., Swan, S., Toppari, J., Tyler, C. R., Vandenberg, L. N., Vinggaard, A. M., Wiberg, K. & Zoeller, R. T., 2013, In : Environmental Health: A Global Access Science Source. 12, p. 69

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2012
  37. Published

    Adverse trends in male reproductive health and decreasing fertility rates

    Priskorn, L., Holmboe, S., Jørgensen, N., Andersson, A-M., Almstrup, K., Toppari, J. & Skakkebæk, N. E., 2012, In : Animal Reproduction Science. p. 760-771 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Association between chemical pattern in breast milk and congenital cryptorchidism: modelling of complex human exposures

    Krysiak-Baltyn, K., Toppari, J., Skakkebaek, N. E., Jensen, T. S., Virtanen, H. E., Schramm, K-W., Shen, H., Vartiainen, T., Kiviranta, H., Taboureau, O., Audouze, K. M. L., Brunak, S. & Main, K. M., 2012, In : International Journal of Andrology. 35, 3, p. 294-302 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Associations between congenital cryptorchidism in newborn boys and levels of dioxins and PCBs in placenta

    Virtanen, H. E., Koskenniemi, J. J., Sundqvist, E., Main, K. M., Kiviranta, H., Tuomisto, J. T., Tuomisto, J., Viluksela, M., Vartiainen, T., Skakkebaek, N. E. & Toppari, J., 2012, In : International Journal of Andrology. 35, 3, p. 283-93 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Goodbye International Journal of Andrology, welcome Andrology!

    Rajpert-De Meyts, E., Eliasson, R., Comhaire, F. H., Skakkebæk, N. E., Sharpe, R. M. & Toppari, J., 2012, In : International Journal of Andrology. 36, 6, p. 769-774 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published
  42. Published

    Possible developmental early effects of endocrine disrupters on child health

    Toppari, J., Adamsson, A., Boas, M., Juul, A., Main, K. M., Skakkebæk, N. E. & Virtanen, HE., 2012, WHO report 2012. p. 1-83

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  43. 2011
  44. Published

    Testicular descent: INSL3, testosterone, genes and the intrauterine milieu

    Bay, K., Main, K. M., Toppari, J., Skakkebæk, N. E. & Medscape, 15 Mar 2011, In : Nature reviews. Urology.

    Research output: Contribution to journalJournal articleResearch

  45. Published

    Prenatal and adult exposures to smoking are associated with adverse effects on reproductive hormones, semen quality, final height and body mass index

    Ravnborg, T. L., Jensen, T. K., Andersson, A-M., Toppari, J., Skakkebæk, N. E. & Jørgensen, N., 18 Feb 2011, In : Human Reproduction. 26, 5, p. 1000-1011 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat

    Kristensen, D. M., Hass, U., Lesné, L., Poulsen, G. L., Jacobsen, P. R., Desdoits-Lethimonier, C., Boberg, J., Petersen, J. H., Toppari, J., Jensen, T. K., Brunak, S., Skakkebaek, N. E., Nellemann, C., Main, K. M., Jégou, B. & Leffers, H., 1 Jan 2011, In : Human Reproduction. 26, 1, p. 235-44 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. 2010
  48. Published
  49. Published

    Differential developmental expression of transcription factors GATA-4 and GATA-6, their cofactor FOG-2 and downstream target genes in testicular carcinoma in situ and germ cell tumors

    Salonen, J., Rajpert-De Meyts, E., Mannisto, S., Nielsen, J. E., Graem, N., Toppari, J. & Heikinheimo, M., 1 Mar 2010, In : European Journal of Endocrinology. 162, 3, p. 625-31 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 2009
  51. Published

    Acquired cryptorchidism is frequent in infancy and childhood

    Wohlfahrt-Veje, C., Boisen, K. A., Boas, M., Damgaard, I. N., Kai, C. M., Schmidt, I. M., Chellakooty, M., Suomi, A-M., Toppari, J., Skakkebaek, N. E. & Main, K. M., Aug 2009, In : International Journal of Andrology. 32, 4, p. 423-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Re: The true incidence of cryptorchidism in Denmark: D. Cortes, E. M. Kjellberg, M. Breddam and J. Thorup, J Urol 2008; 179: 314-318

    Main, K. M., Skakkebaek, N. E. & Toppari, J., Feb 2009, In : The Journal of urology. 181, 2, p. 922-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Cryptorchidism as part of the testicular dysgenesis syndrome: the environmental connection

    Main, K. M., Skakkebaek, N. E. & Toppari, J., 2009, Cryptorchidism as part of the testicular dysgenesis syndrome: the environmental connection. Vol. 14. p. 167-73 7 p. (Endocrine Development).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  54. 2008
  55. Published

    Public health implications of altered puberty timing

    Golub, M. S., Collman, G. W., Foster, P. M. D., Kimmel, C. A., Rajpert-De Meyts, E., Reiter, E. O., Sharpe, R. M., Skakkebaek, N. E. & Toppari, J., Feb 2008, In : Pediatrics. 121 Suppl 3, p. S218-30

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published
  57. Published

    Risk factors for congenital cryptorchidism in a prospective birth cohort study

    Damgaard, I. N., Jensen, T. K., Petersen, J. H., Skakkebaek, N. E., Toppari, J., Main, K. M. & Nordic Cryptorchidism Study Group, 2008, In : P L o S One. 3, 8, p. e3051

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. 2007
  59. Published

    Insulin-like factor 3 levels in cord blood and serum from children: effects of age, postnatal hypothalamic-pituitary-gonadal axis activation, and cryptorchidism

    Bay, K., Virtanen, H. E., Hartung, S., Ivell, R., Main, K. M., Skakkebaek, N. E., Andersson, A-M., Toppari, J. & Nordic Cryptorchidism Study Group, 1 Oct 2007, In : Journal of Clinical Endocrinology and Metabolism. 92, 10, p. 4020-7 8 p.

    Research output: Contribution to journalJournal articleResearch

  60. Published

    Flame retardants in placenta and breast milk and cryptorchidism in newborn boys

    Main, K. M., Kiviranta, H., Virtanen, H. E., Sundqvist, E., Tuomisto, J. T., Tuomisto, J., Vartiainen, T., Skakkebaek, N. E. & Toppari, J., Oct 2007, In : Environmental Health Perspectives. 115, 10, p. 1519-26 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Inhibition of tyrosine kinases PDGFR and C-Kit by imatinib mesylate interferes with postnatal testicular development in the rat

    Nurmio, M., Toppari, J., Zaman, F., Andersson, A. M., Paranko, J., Söder, O. & Jahnukainen, K., 1 Aug 2007, In : International Journal of Andrology. 30, 4, p. 366-376 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Development and descent of the testis in relation to cryptorchidism

    Virtanen, H. E., Cortes, D., Rajpert-De Meyts, E., Ritzén, E. M., Nordenskjöld, A., Skakkebaek, N. E. & Toppari, J., May 2007, In : Acta paediatrica. 96, 5, p. 622-7 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  63. Published

    Nordic consensus on treatment of undescended testes

    Ritzén, E. M., Bergh, A., Bjerknes, R., Christiansen, P., Cortes, D., Haugen, S. E., Jörgensen, N., Kollin, C., Lindahl, S., Läckgren, G., Main, K. M., Nordenskjöld, A., Rajpert-De Meyts, E., Söder, O., Taskinen, S., Thorsson, A., Thorup, J., Toppari, J. & Virtanen, H., May 2007, In : Acta paediatrica. 96, 5, p. 638-43 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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