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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2019
  2. Published

    Infant airway microbiota and topical immune perturbations in the origins of childhood asthma

    Thorsen, J., Rasmussen, M. A., Waage, J., Mortensen, M., Brejnrod, A., Bønnelykke, K., Chawes, B. L., Brix, S., Sørensen, S. J., Stokholm, J. & Bisgaard, H., 1 Nov 2019, In : Nature Communications. 10, 1, p. 5001 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria

    Ahluwalia, T. S., Schulz, C-A., Waage, J., Skaaby, T., Sandholm, N., van Zuydam, N., Charmet, R., Bork-Jensen, J., Almgren, P., Thuesen, B. H., Bedin, M., Brandslund, I., Christensen, C. K., Linneberg, A., Ahlqvist, E., Groop, P-H., Hadjadj, S., Tregouet, D-A., Jørgensen, M. E., Grarup, N., Pedersen, O., Simons, M., Groop, L., Orho-Melander, M., McCarthy, M. I., Melander, O., Rossing, P., Kilpeläinen, T. O. & Hansen, T., 1 Feb 2019, In : Diabetologia. 62, 2, p. 292-305 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published
  5. 2018
  6. Published

    Consortium-based genome-wide meta-analysis for childhood dental caries traits

    Haworth, S., Shungin, D., van der Tas, J. T., Vucic, S., Medina-Gomez, C., Yakimov, V., Feenstra, B., Shaffer, J. R., Lee, M. K., Standl, M., Thiering, E., Wang, C., Bønnelykke, K., Waage, J., Jessen, L. E., Nørrisgaard, P. E., Joro, R., Seppälä, I., Raitakari, O., Dudding, T., Grgic, O., Ongkosuwito, E., Vierola, A., Eloranta, A-M., West, N. X., Thomas, S. J., McNeil, D. W., Levy, S. M., Slayton, R., Nohr, E. A., Lehtimäki, T., Lakka, T., Bisgaard, H., Pennell, C., Kühnisch, J., Marazita, M. L., Melbye, M., Geller, F., Rivadeneira, F., Wolvius, E. B., Franks, P. W., Johansson, I. & Timpson, N. J., 1 Sep 2018, In : Human Molecular Genetics. 27, 17, p. 3113-3127 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

    23andMe Research Team, Aug 2018, In : Nature Genetics. 50, 8, p. 1072-1080 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    NKG2D gene variation and susceptibility to viral bronchiolitis in childhood

    Pasanen, A., Karjalainen, M. K., Kummola, L., Waage, J., Bønnelykke, K., Ruotsalainen, M., Piippo-Savolainen, E., Goksör, E., Nuolivirta, K., Chawes, B., Vissing, N., Bisgaard, H., Jartti, T., Wennergren, G., Junttila, I., Hallman, M., Korppi, M. & Rämet, M., 9 Jun 2018, In : Pediatric Research. 84, p. 451-457 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published
  10. Published

    CDHR3 Genetics and Rhinovirus C Respiratory Illnesses

    Bønnelykke, K., Coleman, A. T., Evans, M. D., Thorsen, J., Waage, J., Vissing, N. H., Carlsson, C. J., Stokholm, J., Chawes, B. L., Jessen, L. E., Fischer, T. K., Bochkov, Y. A., Ober, C., Lemanske, R. F., Jackson, D. J., Gern, J. E. & Bisgaard, H., 1 Mar 2018, In : American Journal of Respiratory and Critical Care Medicine. 197, 5, p. 589-594 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Publisher Correction: Maturation of the gut microbiome and risk of asthma in childhood

    Stokholm, J., Blaser, M. J., Thorsen, J., Rasmussen, M. A., Waage, J., Vinding, R. K., Schoos, A-M. M., Kunøe, A., Fink, N. R., Chawes, B. L., Bønnelykke, K., Brejnrod, A. D., Mortensen, M. S., Al-Soud, W. A., Sørensen, S. J. & Bisgaard, H., 13 Feb 2018, In : Nature Communications. 9, 1, 704.

    Research output: Contribution to journalJournal articleCommunication

  12. Published

    Maturation of the gut microbiome and risk of asthma in childhood

    Stokholm, J., Blaser, M. J., Thorsen, J., Rasmussen, M. A., Waage, J., Vinding, R. K., Schoos, A-M. M., Kunøe, A., Fink, N. R., Chawes, B. L., Bønnelykke, K., Brejnrod, A. D., Mortensen, M. S., Al-Soud, W. A., Sørensen, S. J. & Bisgaard, H., 10 Jan 2018, In : Nature Communications. 9, 1, p. 1-10 10 p., 141.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

    Demenais, F., Margaritte-Jeannin, P., Barnes, K. C., Cookson, W. O. C., Altmüller, J., Ang, W., Barr, R. G., Beaty, T. H., Becker, A. B., Beilby, J., Bisgaard, H., Bjornsdottir, U. S., Bleecker, E., Bønnelykke, K., Boomsma, D. I., Bouzigon, E., Brightling, C. E., Brossard, M., Brusselle, G. G., Burchard, E., Burkart, K. M., Bush, A., Chan-Yeung, M., Chung, K. F., Couto Alves, A., Curtin, J. A., Custovic, A., Daley, D., de Jongste, J. C., Del-Rio-Navarro, B. E., Donohue, K. M., Duijts, L., Eng, C., Eriksson, J. G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M. A., Freidin, M. B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S. A., Gilliland, F., Granell, R., Graves, P. E., Waage, J., Wareham, N. J. & Australian Asthma Genetics Consortium (AAGC) collaborators, Jan 2018, In : Nature Genetics. 50, 1, p. 42-53 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2017
  15. Published

    CDHR3 gene variation and childhood bronchiolitis

    Husby, A., Pasanen, A., Waage, J., Sevelsted, A., Hodemaekers, H., Janssen-Regelink, R., Karjalainen-Lindsberg, M-L., Stokholm, J., Chawes, B. L., Korppi, M., Wennergren, G., Heinzmann, A., Bont, L., Bisgaard, H. & Bønnelykke, K., Nov 2017, In : The Journal of allergy and clinical immunology. 140, 5, p. 1469-1471.e7 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Prenatal vitamin D supplementation reduces risk of asthma/recurrent wheeze in early childhood: A combined analysis of two randomized controlled trials

    Wolsk, H. M., Chawes, B. L., Litonjua, A. A., Hollis, B. W., Waage, J., Stokholm, J., Bønnelykke, K., Bisgaard, H. & Weiss, S. T., 27 Oct 2017, In : P L o S One. 12, 10, p. 1-15 15 p., e0186657.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Shared genetic variants suggest common pathways in allergy and autoimmune diseases

    Kreiner, E., Waage, J., Standl, M., Brix, S., Pers, T. H., Da Silva Couto Alves, A., Warrington, N. M., Tiesler, C. M., Fuertes, E., Franke, L., Hirschhorn, J. N., James, A., Simpson, A., Tung, J. Y., Koppelman, G. H., Postma, D. S., Pennell, C. E., Jarvelin, M-R., Custovic, A., Timpson, N., Ferreira, M. A., Strachan, D. P., Henderson, J., Hinds, D. A., Bisgaard, H. & Bønnelykke, K., Sep 2017, In : The Journal of allergy and clinical immunology. 140, 3, p. 771-781

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma

    Smith, D., Helgason, H., Sulem, P., Bjornsdottir, U. S., Lim, A. C., Sveinbjornsson, G., Hasegawa, H., Brown, M. P., Ketchem, R. R., Gavala, M., Garrett, L., Jonasdottir, A., Jonasdottir, A., Sigurdsson, A., Magnusson, O. T., Eyjolfsson, G. I., Olafsson, I., Onundarson, P. T., Sigurdardottir, O., Gislason, D., Gislason, T., Ludviksson, B. R., Ludviksdottir, D., Boezen, H. M., Heinzmann, A., Krueger, M., Porsbjerg, C., Ahluwalia, T. V. S., Waage, J., Backer, V., Deichmann, K. A., Koppelman, G. H., Bønnelykke, K., Bisgaard, H., Masson, G., Thorsteinsdottir, U., Gudbjartsson, D. F., Johnston, J. A., Jonsdottir, I. & Stefansson, K., Mar 2017, In : P L o S Genetics. 13, 3, p. e1006659

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2016
  20. Published

    The developing hypopharyngeal microbiota in early life

    Mortensen, M. S., Brejnrod, A. D., Roggenbuck, M., Abu Al-Soud, W. M. A. F., Balle, C., Krogfelt, K. A., Stokholm, J., Thorsen, J., Waage, J., Rasmussen, M. A., Bisgaard, H. & Sørensen, S. J., 30 Dec 2016, In : Microbiome. 4, 1, p. 70 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published
  22. Published

    Genome-wide analysis identifies 12 loci influencing human reproductive behavior

    Barban, N., Jansen, R., de Vlaming, R., Vaez, A., Mandemakers, J. J., Tropf, F. C., Shen, X., Wilson, J. F., Chasman, D. I., Nolte, I. M., Tragante, V., van der Laan, S. W., Perry, J. R. B., Kong, A., Ahluwalia, T. V. S., Albrecht, E., Yerges-Armstrong, L., Atzmon, G., Auro, K., Ayers, K., Bakshi, A., Ben-Avraham, D., Berger, K., Bergman, A., Bertram, L., Bielak, L. F., Bjornsdottir, G., Bonder, M. J., Broer, L., Bui, M., Barbieri, C., Cavadino, A., Chavarro, J. E., Turman, C., Concas, M. P., Cordell, H. J., Davies, G., Eibich, P., Eriksson, N., Esko, T., Eriksson, J., Falahi, F., Felix, J. F., Fontana, M. A., Franke, L., Gandin, I., Gaskins, A. J., Bisgaard, H., Bønnelykke, K., Waage, J. & BIOS Consortium, Dec 2016, In : Nature Genetics. 48, 12, p. 1462-1472 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Large-scale benchmarking reveals false discoveries and count transformation sensitivity in 16S rRNA gene amplicon data analysis methods used in microbiome studies

    Thorsen, J., Brejnrod, A., Mortensen, M., Rasmussen, M. A., Stokholm, J., Al-Soud, W. A., Sørensen, S., Bisgaard, H. & Waage, J., 25 Nov 2016, In : Microbiome. 4, 1, p. 62

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Incidence and Determinants of Ventilation Tubes in Denmark

    Pedersen, T. M., Mora-Jensen, A-R. C., Waage, J., Bisgaard, H. & Stokholm, J., 22 Nov 2016, In : P L o S One. 11, 11, p. e0165657 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published
  26. Published

    Genome-wide associations for birth weight and correlations with adult disease

    Horikoshi, M., Beaumont, R. N., Day, F. R., Warrington, N. M., Kooijman, M. N., Fernandez-Tajes, J., Feenstra, B., van Zuydam, N. R., Gaulton, K. J., Grarup, N., Bradfield, J. P., Strachan, D. P., Li-Gao, R., Ahluwalia, T. S., Kreiner, E., Rueedi, R., Lyytikäinen, L-P., Cousminer, D. L., Wu, Y., Thiering, E., Wang, C. A., Have, C. T., Hottenga, J-J., Vilor-Tejedor, N., Joshi, P. K., Boh, E. T. H., Ntalla, I., Pitkänen, N., Mahajan, A., van Leeuwen, E. M., Joro, R., Lagou, V., Nodzenski, M., Diver, L. A., Zondervan, K. T., Bustamante, M., Marques-Vidal, P., Mercader, J. M., Bennett, A. J., Rahmioglu, N., Nyholt, D. R., Ma, R. C. W., Tam, C. H. T., Tam, W. H., Waage, J., Sørensen, T. I. A., Bønnelykke, K., Bisgaard, H., Pisinger, C., Vaag, A. A. & CHARGE Consortium Hematology Working Group, 28 Sep 2016, In : Nature. 538, 7624, p. 248-252 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways

    Bustamante, M., Standl, M., Bassat, Q., Vilor-Tejedor, N., Medina-Gomez, C., Bonilla, C., Ahluwalia, T. S., Bacelis, J., Bradfield, J. P., Tiesler, C. M. T., Rivadeneira, F., Ring, S., Vissing, N. H., Fink, N. R., Jugessur, A., Mentch, F. D., Ballester, F., Kriebel, J., Kiefte-de Jong, J. C., Wolsk, H. M., Llop, S., Thiering, E., Beth, S. A., Timpson, N. J., Andersen, J., Schulz, H., Jaddoe, V. W. V., Evans, D. M., Waage, J., Hakonarson, H., Grant, S. F. A., Jacobsson, B., Bønnelykke, K., Bisgaard, H., Davey Smith, G., Moll, H. A., Heinrich, J., Estivill, X. & Sunyer, J., 15 Sep 2016, In : Human Molecular Genetics. 25, 18, p. 4127-4142

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Genome-wide association study identifies 74 loci associated with educational attainment

    Okbay, A., Beauchamp, J. P., Fontana, M. A., Lee, J. J., Pers, T. H., Rietveld, C. A., Turley, P., Chen, G-B., Emilsson, V., Meddens, S. F. W., Oskarsson, S., Pickrell, J. K., Thom, K., Timshel, P., de Vlaming, R., Abdellaoui, A., Ahluwalia, T. S., Bacelis, J., Baumbach, C., Bjornsdottir, G., Brandsma, J. H., Pina Concas, M., Derringer, J., Furlotte, N. A., Galesloot, T. E., Girotto, G., Gupta, R., Hall, L. M., Harris, S. E., Hofer, E., Horikoshi, M., Huffman, J. E., Kaasik, K., Kalafati, I. P., Karlsson, R., Kong, A., Lahti, J., van der Lee, S. J., deLeeuw, C., Lind, P. A., Lindgren, K-O., Liu, T., Mangino, M., Marten, J., Mihailov, E., Miller, M. B., Bønnelykke, K., Waage, J., Bisgaard, H., Sørensen, T. I. A. & LifeLines Cohort Study, 26 May 2016, In : Nature. 533, 7604, p. 539-42 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    UPF2-Dependent Nonsense-Mediated mRNA Decay Pathway Is Essential for Spermatogenesis by Selectively Eliminating Longer 3'UTR Transcripts

    Bao, J., Vitting-Seerup, K., Waage, J., Tang, C., Ge, Y., Porse, B. T. & Yan, W., May 2016, In : P L o S Genetics. 12, 5, p. e1005863

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Domestic Dog Exposure at birth reduces the Incidence of Atopic Dermatitis

    Thorsteinsdottir, S., Thyssen, J. P., Stokholm, J., Vissing, N. H., Waage, J. & Bisgaard, H., 23 Feb 2016, In : Allergy. 35, 5, p. 561-566 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

    Felix, J. F., Bradfield, J. P., Monnereau, C., van der Valk, R. J. P., Stergiakouli, E., Chesi, A., Gaillard, R., Feenstra, B., Thiering, E., Kreiner-Møller, E., Mahajan, A., Pitkänen, N., Joro, R., Cavadino, A., Huikari, V., Franks, S., Groen-Blokhuis, M. M., Cousminer, D. L., Marsh, J. A., Lehtimäki, T., Curtin, J. A., Vioque, J., Ahluwalia, T. S., Myhre, R., Price, T. S., Vilor-Tejedor, N., Yengo, L., Grarup, N., Ntalla, I., Ang, W., Atalay, M., Bisgaard, H., Blakemore, A. I., Bonnefond, A., Carstensen, L., Eriksson, J., Flexeder, C., Franke, L., Geller, F., Geserick, M., Hartikainen, A-L., Haworth, C. M. A., Hirschhorn, J. N., Hofman, A., Holm, J-C., Horikoshi, M., Pers, T. H., Waage, J., Bønnelykke, K., Sørensen, T. I. A. & Bone Mineral Density in Childhood Study (BMDCS), 15 Jan 2016, In : Human Molecular Genetics. 25, 2, p. 389-403 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2015
  33. Published

    Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

    Waage, J., Bønnelykke, K., Thyssen, J. P., Kreiner-Møller, E., Bisgaard, H., EArly Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium (Ried JS, Li J, Zuo XB, Zheng XD, Yin XY, Sun LD, McAleer MA, O'Regan GM, Fahy CM, Campbell LE, Macek M, Kurek M, Hu D, Eng C, Postma DS, Feenstra B, Geller F, Hottenga JJ, Middeldorp CM, Hysi P, Bataille V, Spector T, Tiesler CM, Thiering E, Pahukasahasram B, Yang JJ, Imboden M, Huntsman S, Vilor-Tejedor N, Relton CL, Myhre R, Nystad W, Custovic A, Weiss ST, Meyers DA, Söderhäll C, Melén E, Ober C, Raby BA, Simpson A, Jacobsson B, Holloway JW, Bisgaard H, Sunyer J, Probst-Hensch NM, Williams LK, Godfrey KM, Wang CA, Boomsma DI, Melbye M, Koppelman GH, Jarvis D, McLean WH, Irvine AD, Zhang XJ, Hakonarson H, Gieger C, Burchard EG, Martin NG, Duijts L, Linneberg A, Jarvelin MR, Nöthen MM, Lau S, Hübner N, Lee YA, Tamari M, Hinds DA, Glass D, Brown SJ, Heinrich J, Evans DM, Weidinger S, members) & Linneberg, A., Dec 2015, In : Nature Genetics. 47, 12, p. 1449-56 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Genetics of allergy and allergic sensitization: common variants, rare mutations

    Bønnelykke, K., Sparks, R., Waage, J. & Milner, J. D., Oct 2015, In : Current Opinion in Immunology. 36, p. 115-26 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    A novel common variant in DCST2 is associated with length in early life and height in adulthood

    van der Valk, R. J. P., Kreiner-Møller, E., Kooijman, M. N., Guxens, M., Stergiakouli, E., Sääf, A., Bradfield, J. P., Geller, F., Hayes, M. G., Cousminer, D. L., Körner, A., Thiering, E., Curtin, J. A., Myhre, R., Huikari, V., Joro, R., Kerkhof, M., Warrington, N. M., Pitkänen, N., Ntalla, I., Horikoshi, M., Veijola, R., Freathy, R. M., Teo, Y-Y., Barton, S. J., Evans, D. M., Kemp, J. P., St Pourcain, B., Ring, S. M., Davey Smith, G., Bergström, A., Kull, I., Hakonarson, H., Mentch, F. D., Bisgaard, H., Chawes, B., Stokholm, J., Waage, J., Eriksen, P., Sevelsted, A., Melbye, M., van Duijn, C. M., Medina-Gomez, C., Hofman, A., de Jongste, J. C., Taal, H. R., Uitterlinden, A. G., Armstrong, L. L., Eriksson, J., Bønnelykke, K. & Early Genetics and Lifecourse Epidemiology (EAGLE) Consortium, 15 Feb 2015, In : Human Molecular Genetics. 24, 4, p. 1155-68 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Amplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq

    Jakobsen, J. S., Bagger, F. O., Hasemann, M. S., Schuster, M. B., Frank, A-K., Waage, J., Vitting-Seerup, K. & Porse, B. T., 5 Feb 2015, In : B M C Genomics. 16, 1, p. 46

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia

    Willer, A., Jakobsen, J. S., Ohlsson, E., Rapin, N., Waage, J., Billing, M., Bullinger, L., Karlsson, S. & Porse, B. T., 2015, In : Leukemia. 29, p. 1018-1031

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. 2014
  39. Published

    spliceR: an R package for classification of alternative splicing and prediction of coding potential from RNA-seq data

    Vitting-Seerup, K., Porse, B. T., Sandelin, A. G. & Waage, J., 23 Mar 2014, In : B M C Bioinformatics. 15, 1, p. 81

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published
  41. 2013
  42. Published

    Applications of High-Throughput Nucleotide Sequencing (PhD)

    Waage, J., 18 Nov 2013, Eget Forlag. 118 p.

    Research output: Book/ReportPh.D. thesisResearch

  43. Published

    microRNA-9 targets the long non-coding RNA MALAT1 for degradation in the nucleus

    Leucci, E., Patella, F., Waage, J., Holmstrøm, K., Lindow, M., Porse, B., Kauppinen, M. S. & Lund, A. H., 29 Aug 2013, In : Scientific Reports. 3, p. 2535

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published
  45. 2012
  46. Published

    Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns

    Weischenfeldt, J., Waage, J., Tian, G., Zhao, J., Damgaard, I., Jakobsen, J. S., Kristiansen, K., Krogh, A. S., Wang, J. & Porse, B. T., 2012, In : Genome Biology (Online Edition). 13, 5, p. R35

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 33285632