Personal profile
Expertises
JU Jensen has a background in sepsis, respiratory failure and biomarker research and has lead several multicentre randomized controlled trials in intensive care units across Europe and USA. Currently, Study Director of the Cooling And Surviving Septic shock trial (CASS-trial), a study to test the hypothesis of whether mild induced hypothermia can improve survival in septic shock patients by improving tissue perfusion, preserving mitochondrial function.
Apart from generating and testing hypotheses regarding antibiotic strategies and other ways of infection control, Dr. Jensen has lead several studies of endothelial dysfunction, coagulopathies in sepsis, renal dysfunction in critical illness and pathophysiological studies. Dr. Jensen has been awarded the 2013 Hellsing prize from the Nordic Society for Clinical Biochemistry for his work on the relation between biomarker performance and clinical effects.
He has supervised two successfully defended PhD´s and is currently supervising 3 phd students. 43 publications. 827 citations. H-index 10.
International collaborators include the Outcomes Research at Cleveland Clinic, Ohio, USA and ICU research at the Academic Medical Centre (AMC) in Amsterdam
Main research areas
Sepsis; Acute Respiratory Failure; Biomarkers; COPD;
Current research
Randomized trial on mild induced hypothermia in Septic Shock
Liver failure in Sepsis
Genomic host characteristics in Sepsis and clinical consequences
Individualized corticosteroid therapy in COPD
The Role of chronic colonisation of the airways in COPD
Potential conflicts of interest
2016: ERS congress participation arranged by Roche pharmaceuticals.
2011-2016: Discount on cooling devices for an investigator-initated and driven RCT. Companies: ZOLL, BARD and EMCOOLS.
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Collaborations and top research areas from the last five years
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A Pragmatic Individually Randomized Trial to Evaluate Bivalent RSV Prefusion F Protein-based Vaccine Effectiveness for Preventing RSV Hospitalizations in Adults Aged 60 Years or Above (DAN-RSV): Rationale and trial design
Lassen, M. C. H., Christensen, S. H., Johansen, N. D., Aliabadi, N., Skaarup, K. G., Modin, D., Claggett, B. L., Larsen, C. S., Larsen, L., Wiese, L., Dalager-Pedersen, M., Lindholm, M. G., Køber, L., Solomon, S. D., Stæhr Jensen, J. U., Martel, C.J.-M., Schwarz, C., Gonzalez, E., Skovdal, M. & Moulton, L. H. & 4 others, , Jan 2026, In: American Heart Journal. 291, p. 14-25 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus) -
A Pragmatic Individually Randomized Trial to Evaluate the Effectiveness of High-Dose vs. Standard-Dose Influenza Vaccine in Older Adults: Rationale and Design of the DANFLU-2 Trial
Johansen, N. D., Modin, D., Loiacono, M. M., Harris, R. C., Dufournet, M., Larsen, C. S., Larsen, L., Wiese, L., Dalager-Pedersen, M., Claggett, B. L., Skaarup, K. G., Davidovski, F. S., Solomon, S. D., Landray, M. J., Gislason, G. H., Køber, L., Sivapalan, P., Martel, C.J.-M., Jensen, J. U. S. & Biering-Sørensen, T., Jan 2026, In: American Heart Journal. 291, p. 186-198 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
Characteristics of bronchiectasis in patients with different genotypes of severe α1-antitrypsin deficiency from the EARCO registry
Mirizzi, F. M., Aljama, C., Santus, P., Mantero, M., Omcikus, M., Torres-Duran, M., Turner, A. M., Tanash, H., Rodríguez-García, C., Jensen, J. U. S., Corsico, A. G., López-Campos, J. L., Chapman, K. R., Clarenbach, C., Guimaraes, C., Bartošovská, E., Hernández-Pérez, J. M., Miravitlles, M., Esquinas, C. & Barrecheguren, M. & 1 others, , Jan 2026, In: ERJ Open Research. 12, 1, 00491-2025.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Chronic obstructive pulmonary disease and rheumatoid arthritis: severe exacerbations, pneumonia, and death in a population-based cohort
Hyldgaard, C., Bonnesen, B., Vognsen, A. K., Sivapalan, P., Eklöf, J., Jordan, A. S., Bendstrup, E., Ellingsen, T. & Jensen, J. U. S., 2026, (Accepted/In press) In: Scandinavian Journal of Rheumatology.Research output: Contribution to journal › Journal article › Research › peer-review
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COPD and vitamin K antagonism: a cohort study of 1-year all-cause mortality and risk of hospitalisation due to a severe exacerbation
Gundersen, B.-E. V. V., Vognsen, A. K., Eklöf, J., Sivapalan, P., Linneberg, A., Biering-Sørensen, T. & Jensen, J.-U. S., 27 Jan 2026, In: BMJ Open Respiratory Research. 13, 1, p. e003814 e003814.Research output: Contribution to journal › Journal article › Research › peer-review