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The Capital Region of Denmark - a part of Copenhagen University Hospital

Jens J. Holst

(Former)

  1. 2019
  2. Published

    Investigating Intestinal Glucagon after Roux-en-Y Gastric Bypass Surgery

    Jorsal, T., Wewer Albrechtsen, N. J., Christensen, M. M., Mortensen, B., Wandall, E., Langholz, E., Friis, S., Worm, D., Ørskov, C., Støving, R. K., Andries, A., Juhl, C. B., Sørensen, F., Forman, J. L., Falkenhahn, M., Musholt, P. B., Theis, S., Larsen, P. J., Holst, J. J., Vrang, N., Jelsing, J., Vilsbøll, T. & Knop, F. K., 1 Dec 2019, In : The Journal of clinical endocrinology and metabolism. 104, 12, p. 6403-6416 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print
  4. E-pub ahead of print

    Effects of Gender-Affirming Hormone Therapy on Insulin Sensitivity and Incretin Responses in Transgender People

    Shadid, S., Abosi-Appeadu, K., De Maertelaere, A-S., Defreyne, J., Veldeman, L., Holst, J. J., Lapauw, B., Vilsbøll, T. & T'Sjoen, G., 18 Nov 2019, In : Diabetes Care.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. E-pub ahead of print

    A Low Dose of Pasireotide Prevents Hypoglycemia in Roux-en-Y Gastric Bypass-Operated Individuals

    Øhrstrøm, C. C., Hansen, D. L., Kielgast, U. L., Hartmann, B., Holst, J. J. & Worm, D., 10 Nov 2019, In : Obesity Surgery.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. E-pub ahead of print

    Evaluation of the incretin effect in humans using GIP and GLP-1 receptor antagonists

    Gasbjerg, L. S., Bergmann, N. C., Stensen, S., Christensen, M. B., Rosenkilde, M. M., Holst, J. J., Nauck, M. & Knop, F. K., 3 Nov 2019, In : Peptides.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published
  8. Published

    Copeptin, a surrogate marker for arginine vasopressin secretion, is positively associated with glucagon

    Asferg, C. L., Andersen, U. B., Linneberg, A., Goetze, J. P., Holst, J. J. & Jeppesen, J. L., Nov 2019, In : Diabetic Medicine. 36, 11, p. 1408-1411 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. E-pub ahead of print

    Glucose-dependent insulinotropic polypeptide is a pancreatic polypeptide secretagogue in humans

    Veedfald, S., Vedtofte, L., Skov-Jeppesen, K., Deacon, C. F., Hartmann, B., Vilsbøll, T., Knop, F. K., Christensen, M. B. & Holst, J. J., 26 Oct 2019, In : The Journal of clinical endocrinology and metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published
  11. E-pub ahead of print
  12. E-pub ahead of print

    GIP's effect on bone metabolism is reduced by the selective GIP receptor antagonist GIP(3-30)NH2

    Gasbjerg, L. S., Hartmann, B., Christensen, M. B., Lanng, A. R., Vilsbøll, T., Jørgensen, N. R., Holst, J. J., Rosenkilde, M. M. & Knop, F. K., 14 Oct 2019, In : The Bone. 130, 115079.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Greater glucagon-like peptide-1 responses to oral glucose are associated with lower central and peripheral blood pressures

    Lundgren, J. R., Færch, K., Witte, D. R., Jonsson, A. E., Pedersen, O., Hansen, T., Lauritzen, T., Holst, J. J., Vistisen, D., Jørgensen, M. E., Torekov, S. S. & Johansen, N. B., 5 Oct 2019, In : Cardiovascular Diabetology. 18, 1, 130.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Gluco-metabolic effects of oral and intravenous alcohol administration in men

    Lanng, A. R. R., Gasbjerg, L. S., Bergmann, N. C., Bermann, S., Helsted, M. M., Gillum, M. P., Hartmann, B., Holst, J. J., Vilsbøll, T. & Knop, F. K., Oct 2019, In : Endocrine Connections. 8, 10, p. 1372–1382 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Postprandial hypoglycaemia after Roux-en-Y gastric bypass and the effects of acarbose, sitagliptin, verapamil, liraglutide and pasireotide

    Øhrstrøm, C. C., Worm, D., Højager, A., Andersen, D., Holst, J. J., Kielgast, U. L. & Hansen, D. L., Sep 2019, In : Diabetes, Obesity and Metabolism. 21, 9, p. 2142-2151 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Pros and cons of Roux en-Y gastric bypass surgery in obese patients with type 2 diabetes

    Justinussen, T., Madsbad, S., Holst, J. J. & Bojsen-Møller, K. N., 14 Jul 2019, In : Expert Review of Endocrinology & Metabolism. 14, 4, p. 243-257 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Glucagon Receptor Signaling and Glucagon Resistance

    Janah, L., Kjeldsen, S., Galsgaard, K. D., Winther-Sørensen, M., Stojanovska, E., Pedersen, J., Knop, F. K., Holst, J. J. & Wewer Albrechtsen, N. J., 5 Jul 2019, In : International Journal of Molecular Sciences. 20, 13, 3314.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Plasma FGF-19 Levels are Increased in Patients with Post-Bariatric Hypoglycemia

    Mulla, C. M., Goldfine, A. B., Dreyfuss, J. M., Houten, S., Pan, H., Pober, D. M., Wewer Albrechtsen, N. J., Svane, M. S., Schmidt, J. B., Holst, J. J., Craig, C. M., McLaughlin, T. L. & Patti, M-E., Jul 2019, In : Obesity Surgery. 29, 7, p. 2092-2099 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published
  20. Published

    Fatty Liver Among Adolescent Offspring of Women With Type 1 Diabetes (the EPICOM Study)

    Knorr, S., Bytoft, B., Lohse, Z., Boisen, A. B., Clausen, T. D., Jensen, R. B., Damm, P., Beck-Nielsen, H., Holst, J. J., Hartmann, B., Møller, H. J., Højlund, K., Gravholt, C. H. & Jensen, D. M., 4 Jun 2019, In : Diabetes Care. 42, 8, p. 1560-68

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. E-pub ahead of print

    Sacubitril/valsartan augments postprandial plasma concentrations of active GLP-1 when combined with sitagliptin in men

    Wewer Albrechtsen, N. J., Mark, P. D., Terzic, D., Hansen, L. H., Andersen, U. Ø., Hartmann, B., Carr, R. D., Gustafsson, F., Deacon, C. F., Holst, J. J., Goetze, J. P. & Plomgaard, P., 10 May 2019, In : The Journal of clinical endocrinology and metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. E-pub ahead of print

    GIP-induced vasodilation in human adipose tissue involves capillary recruitment

    Asmar, M., Asmar, A., Simonsen, L., Dela, F., Holst, J. J. & Bülow, J., 1 May 2019, In : Endocrine Connections.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published
  24. Published
  25. Published

    Separate and Combined Gluco-Metabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-Like Peptide-1 in Healthy Individuals

    Gasbjerg, L. S., Helsted, M. M., Hartmann, B., Jensen, M. H., Gabe, M. B. N., Sparre-Ulrich, A. H., Veedfald, S., Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, M. B., Vilsbøll, T., Holst, J. J., Rosenkilde, M. M. & Knop, F. K., May 2019, In : Diabetes. 68, 5, p. 906-917 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Effects of combined GIP and GLP-1 infusion on energy intake, appetite and energy expenditure in overweight/obese individuals: a randomised, crossover study

    Bergmann, N. C., Lund, A., Gasbjerg, L. S., Meessen, E. C. E., Andersen, M. M., Bergmann, S., Hartmann, B., Holst, J. J., Jessen, L., Christensen, M. B., Vilsbøll, T. & Knop, F. K., 1 Apr 2019, In : Diabetologia. 62, 4, p. 665-675 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Gastrointestinal motility in patients with end-stage renal disease on chronic hemodialysis

    Broberg, B., Madsen, J. L., Fuglsang, S., Holst, J. J., Christensen, K. B., Rydahl, C., Idorn, T., Feldt-Rasmussen, B. & Hornum, M., Apr 2019, In : Neurogastroenterology and Motility. 31, 4, p. e13554 e13554.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Glucagon Receptor Signaling and Lipid Metabolism

    Galsgaard, K. D., Pedersen, J., Knop, F. K., Holst, J. J. & Wewer Albrechtsen, N. J., Apr 2019, In : Frontiers in physiology. 10, p. 1-11 11 p., 413.

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    Preserved glucose response to low-dose glucagon after exercise in insulin-pump-treated individuals with type 1 diabetes: a randomised crossover study

    Steineck, I. I. K., Ranjan, A., Schmidt, S., Clausen, T. R., Holst, J. J. & Nørgaard, K., Apr 2019, In : Diabetologia. 62, 4, p. 582-592 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Bariatric surgery-which procedure is the optimal choice?

    Madsbad, S. & Holst, J. J., 30 Mar 2019, In : Lancet (London, England). 393, 10178, p. 1263-1264 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published
  32. Published

    Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease

    Niu, L., Geyer, P. E., Wewer Albrechtsen, N. J., Gluud, L. L., Santos, A., Doll, S., Treit, P. V., Holst, J. J., Knop, F. K., Vilsbøll, T., Junker, A., Sachs, S., Stemmer, K., Müller, T. D., Tschöp, M. H., Hofmann, S. M. & Mann, M., 1 Mar 2019, In : Molecular Systems Biology. 15, 3, 16 p., e8793.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published
  34. E-pub ahead of print
  35. E-pub ahead of print
  36. Published
  37. Published

    Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial

    Roager, H. M., Vogt, J. K., Kristensen, M., Hansen, L. B. S., Ibrügger, S., Mærkedahl, R. B., Bahl, M. I., Lind, M. V., Nielsen, R. L., Frøkiær, H., Gøbel, R. J., Landberg, R., Ross, A. B., Brix, S., Holck, J., Meyer, A. S., Sparholt, M. H., Christensen, A. F., Carvalho, V., Holst, J. J., Rumessen, J. J., Linneberg, A., Sicheritz-Pontén, T., Dalgaard, M. D., Blennow, A., Frandsen, H. L., Villas-Bôas, S., Kristiansen, K., Vestergaard, H., Hansen, T., Ekstrøm, C. T., Ritz, C., Nielsen, H. B., Pedersen, O. B., Gupta, R., Lauritzen, L. & Licht, T. R., 1 Jan 2019, In : Gut. 68, 1, p. 83-93 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. 2018
  39. Published
  40. Published

    Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes

    Bahne, E., Sun, E. W. L., Young, R. L., Hansen, M., Sonne, D. P., Hansen, J. S., Rohde, U., Liou, A. P., Jackson, M. L., de Fontgalland, D., Rabbitt, P., Hollington, P., Sposato, L., Due, S., Wattchow, D. A., Rehfeld, J. F., Holst, J. J., Keating, D. J., Vilsbøll, T. & Knop, F. K., 6 Dec 2018, In : JCI Insight. 3, 23, p. 93936

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery

    Wewer Albrechtsen, N. J., Geyer, P. E., Doll, S., Treit, P. V., Bojsen-Møller, K. N., Martinussen, C., Jørgensen, N. B., Torekov, S. S., Meier, F., Niu, L., Santos, A., Keilhauer, E. C., Holst, J. J., Madsbad, S. & Mann, M., 5 Dec 2018, In : Cell Systems . 7, 6, p. 601-612

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Response to: Letter to the Editor: Hemodynamic Effects of Glucagon - A literature Review

    Meidahl Petersen, K., Bøgevig, S., Holst, J. J., Knop, F. K. & Christensen, M. B., 1 Dec 2018, In : The Journal of clinical endocrinology and metabolism. 103, 12, p. 4480–4481 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  43. Published
  44. Published

    A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults

    Hansen, L. B. S., Roager, H. M., Søndertoft, N. B., Gøbel, R. J., Kristensen, M., Vallès-Colomer, M., Vieira-Silva, S., Ibrügger, S., Lind, M. V., Mærkedahl, R. B., Bahl, M. I., Madsen, M. L., Havelund, J., Falony, G., Tetens, I., Nielsen, T., Allin, K. H., Frandsen, H. L., Hartmann, B., Holst, J. J., Sparholt, M. H., Holck, J., Blennow, A., Moll, J. M., Meyer, A. S., Hoppe, C., Poulsen, J. H., Carvalho, V., Sagnelli, D., Dalgaard, M. D., Christensen, A. F., Lydolph, M. C., Ross, A. B., Villas-Bôas, S., Brix, S., Sicheritz-Pontén, T., Buschard, K., Linneberg, A., Rumessen, J. J., Ekstrøm, C. T., Ritz, C., Kristiansen, K., Nielsen, H. B., Vestergaard, H., Færgeman, N. J., Raes, J., Frøkiær, H., Hansen, T., Lauritzen, L., Gupta, R., Licht, T. R. & Pedersen, O., 13 Nov 2018, In : Nature Communications. 9, 4630, p. 4630

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Hepatic Insulin Clearance in Regulation of Systemic Insulin Concentrations-Role of Carbohydrate and Energy Availability

    Bojsen-Møller, K. N., Lundsgaard, A-M., Madsbad, S., Kiens, B. & Holst, J. J., Nov 2018, In : Diabetes. 67, 11, p. 2129-2136 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Individual and combined glucose-lowering effects of glucagon receptor antagonism and sodium-glucose cotransporter 2 inhibition

    Hædersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Holst, J. J., Knop, F. K. & Vilsbøll, T., 1 Oct 2018, In : Diabetologia. 61, Suppl 1, p. S312-S312 1 p., 642.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  47. Published

    Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption

    Bergmann, N., Lund, A., Heimbürger, S. M., Gasbjerg, L. S., Jørgensen, N. R., Jessen, L., Hartmann, B., Holst, J. J., Christensen, M., Vilsbøll, T. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, suppl 1, p. S348-S348 1 p., 717.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  48. Published

    Postprandial effects of individual and combined GIP and GLP-1 receptor antagonism in healthy subjects

    Gasbjerg, L. S., Helsted, M. M., Sparre-Ulrich, A. H., Lanng, A. R., Stensen, S., Jakobsen, M. H., Hartmann, B., Christensen, M., Holst, J. J., Vilsbøll, T., Rosenkilde, M. M. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, suppl 1, p. S246-S246 1 p., 503.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  49. Published

    The role of the incretins in the postprandial bone remodelling

    Helsted, M. M., Gasbjerg, L. S., Lanng, A. R., Stensen, S., Hartmann, B., Christensen, M., Holst, J. J., Vilsbøll, T., Rosenkilde, M. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, Suppl 1, p. S221-S221 1 p., 449.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  50. Published

    No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course

    Mikkelsen, K. H., Vilsbøll, T., Holst, J. J., Hartmann, B., Knop, F. K. & Frost, M., 4 Sep 2018, In : BMC Endocrine Disorders. 18, 1, p. 60

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published
  52. Published

    Patients with Obesity Caused by Melanocortin-4 Receptor Mutations Can Be Treated with a Glucagon-like Peptide-1 Receptor Agonist

    Iepsen, E. W., Zhang, J., Thomsen, H. S., Hansen, E. L., Hollensted, M., Madsbad, S., Hansen, T., Holst, J. J., Holm, J-C. & Torekov, S. S., 1 Aug 2018, In : Cell Metabolism. 28, 1, p. 23-32

    Research output: Contribution to journalJournal articleResearchpeer-review

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