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The Capital Region of Denmark - a part of Copenhagen University Hospital
  1. 2018
  2. Published

    Analysis of gonadotrophin-releasing hormone-1 and kisspeptin neuronal systems in the nonphotoregulated seasonally breeding eastern rock elephant-shrew (Elephantulus myurus)

    Medger, K., Bennett, N. C., Chimimba, C. T., Oosthuizen, M. K., Mikkelsen, J. D. & Coen, C. W., 15 Oct 2018, In : The Journal of comparative neurology. 526, 15, p. 2388-2405 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons

    Runegaard, A. H., Sørensen, A. T., Fitzpatrick, C. M., Jørgensen, S. H., Petersen, A. V., Hansen, N. W., Weikop, P., Andreasen, J. T., Mikkelsen, J. D., Perrier, J-F., Woldbye, D., Rickhag, M., Wortwein, G. & Gether, U., 26 Jun 2018, In : eNeuro. 5, 3, p. 1-28 28 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2017
  5. Published

    The Preoptic Area and the RFamide-Related Peptide Neuronal System Gate Seasonal Changes in Chemosensory Processing

    Jennings, K. J., Chasles, M., Cho, H., Mikkelsen, J., Bentley, G., Keller, M. & Kriegsfeld, L. J., 1 Nov 2017, In : Integrative and comparative biology. 57, 5, p. 1055-1065 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published
  7. Published

    Perinatal nicotine treatment induces transient increases in NACHO protein levels in the rat frontal cortex

    Wichern, F., Jensen, M. M., Christensen, D. Z., Mikkelsen, J. D., Gondré-Lewis, M. C. & Thomsen, M. S., 27 Mar 2017, In : Neuroscience. 346, p. 278-283 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Roles of RFRP-3 in the Daily and Seasonal Regulation of Reproductive Activity in Female Syrian Hamsters

    Henningsen, J. B., Ancel, C., Mikkelsen, J. D., Gauer, F. & Simonneaux, V., 1 Mar 2017, In : Endocrinology. 158, 3, p. 652-663 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The pan-Kv7 (KCNQ) Channel Opener Retigabine Inhibits Striatal Excitability by Direct Action on Striatal Neurons In Vivo

    Hansen, H. H., Weikop, P., Mikkelsen, M. D., Rode, F. & Mikkelsen, J. D., Jan 2017, In : Basic & clinical pharmacology & toxicology. 120, 1, p. 46-51 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2016
  11. Published

    Positive allosteric modulators of the α7 nicotinic acetylcholine receptor potentiate glutamate release in the prefrontal cortex of freely-moving rats

    Bortz, D. M., Upton, B. A., Mikkelsen, J. D. & Bruno, J. P., Dec 2016, In : Neuropharmacology. 111, p. 78-91 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Quantification of the functional expression of the Ca(2+) -activated K(+) channel KCa 3.1 on microglia from adult human neocortical tissue

    Blomster, L. V., Strøbaek, D., Hougaard, C., Klein, J., Pinborg, L. H., Mikkelsen, J. D. & Christophersen, P., Dec 2016, In : GLIA. 64, 12, p. 2065-2078 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Lynx1 and Aβ1-42 bind competitively to multiple nicotinic acetylcholine receptor subtypes

    Thomsen, M. S., Arvaniti, M., Jensen, M. M., Shulepko, M. A., Dolgikh, D. A., Pinborg, L. H., Härtig, W., Lyukmanova, E. N. & Mikkelsen, J. D., Oct 2016, In : Neurobiology of Aging. 46, p. 13-21 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Characterization of liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, in rat partial and full nigral 6-hydroxydopamine lesion models of Parkinson's disease

    Hansen, H. H., Fabricius, K., Barkholt, P., Mikkelsen, J. D., Jelsing, J., Pyke, C., Knudsen, L. B. & Vrang, N., 1 Sep 2016, In : Brain Research. 1646, p. 354-65 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Functional interaction between Lypd6 and nicotinic acetylcholine receptors

    Arvaniti, M., Jensen, M. M., Soni, N., Wang, H., Klein, A. B., Thiriet, N., Pinborg, L. H., Muldoon, P. P., Wienecke, J., Imad Damaj, M., Kohlmeier, K. A., Gondré-Lewis, M. C., Mikkelsen, J. D. & Thomsen, M. S., Sep 2016, In : Journal of Neurochemistry. 138, 6, p. 806-20 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Acute phencyclidine administration induces c-Fos-immunoreactivity in interneurons in cortical and subcortical regions

    Hervig, M. E., Thomsen, M. S., Kalló, I. & Mikkelsen, J. D., 29 Jul 2016, In : Neuroscience. 334, p. 13-25 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Heteromeric α7β2 Nicotinic Acetylcholine Receptors in the Brain

    Wu, J., Liu, Q., Tang, P., Mikkelsen, J. D., Shen, J., Whiteaker, P. & Yakel, J. L., Jul 2016, In : Trends in Pharmacological Sciences. 37, 7, p. 562-74 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Sex differences in the photoperiodic regulation of RF-Amide related peptide (RFRP) and its receptor GPR147 in the syrian hamster

    Henningsen, J. B., Poirel, V-J., Mikkelsen, J. D., Tsutsui, K., Simonneaux, V. & Gauer, F., 15 Jun 2016, In : The Journal of comparative neurology. 524, 9, p. 1825-38 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Changes in Binding of [(123)I]CLINDE, a High-Affinity Translocator Protein 18 kDa (TSPO) Selective Radioligand in a Rat Model of Traumatic Brain Injury

    Donat, C. K., Gaber, K., Meixensberger, J., Brust, P., Pinborg, L. H., Hansen, H. H. & Mikkelsen, J. D., Jun 2016, In : NeuroMolecular Medicine. 18, 2, p. 158-69 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published
  21. Published

    Encenicline, an α7 Nicotinic Acetylcholine Receptor Partial Agonist, Reduces Immune Cell Infiltration in the Colon and Improves Experimental Colitis in Mice

    Salaga, M., Blomster, L. V., Piechota-Polańczyk, A., Zielińska, M., Jacenik, D., Cygankiewicz, A. I., Krajewska, W. M., Mikkelsen, J. D. & Fichna, J., Jan 2016, In : The Journal of pharmacology and experimental therapeutics. 356, 1, p. 157-69 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Is a Selective Allosteric Antagonist of α7 Nicotinic Acetylcholine Receptor

    Lyukmanova, E. N., Shulepko, M. A., Kudryavtsev, D., Bychkov, M. L., Kulbatskii, D. S., Kasheverov, I. E., Astapova, M. V., Feofanov, A. V., Thomsen, M. S., Mikkelsen, J. D., Shenkarev, Z. O., Tsetlin, V. I., Dolgikh, D. A. & Kirpichnikov, M. P., 2016, In : P L o S One. 11, 2, p. e0149733

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2015
  24. Published
  25. Published
  26. Published
  27. Published

    Radiosynthesis and in vitro validation of (3)H-NS14492 as a novel high affinity alpha7 nicotinic receptor radioligand

    Magnussen, J. H., Ettrup, A., Donat, C. K., Peters, D., Pedersen, M. H. F., Knudsen, G. M. & Mikkelsen, J. D., 5 Sep 2015, In : European journal of pharmacology. 762, p. 35-41 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published
  29. Published

    High plasma triglyceride levels strongly correlate with low kisspeptin in the arcuate nucleus of male rats

    Overgaard, A., Axel, A. M., Lie, M. E., Hansen, H. H. & Mikkelsen, J. D., Apr 2015, In : Endocrine Regulations. 49, 2, p. 51-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease

    Jensen, M. M., Arvaniti, M., Mikkelsen, J. D., Michalski, D., Pinborg, L. H., Härtig, W. & Thomsen, M. S., Apr 2015, In : Neurobiology of Aging. 36, 4, p. 1629-38 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published
  32. Published

    α7 and β2 Nicotinic Acetylcholine Receptor Subunits Form Heteromeric Receptor Complexes that Are Expressed in the Human Cortex and Display Distinct Pharmacological Properties

    Thomsen, M. S., Zwart, R., Ursu, D., Jensen, M. M., Pinborg, L. H., Gilmour, G., Wu, J., Sher, E. & Mikkelsen, J. D., 2015, In : P L o S One. 10, 6, p. e0130572

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. 2014
  34. Published
  35. Published

    Targeting Dopamine D3 and Serotonin 5-HT1A and 5-HT2A Receptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and Behavioral Studies

    Brindisi, M., Butini, S., Franceschini, S., Brogi, S., Trotta, F., Ros, S., Cagnotto, A., Salmona, M., Casagni, A., Andreassi, M., Saponara, S., Gorelli, B., Weikop, P., Mikkelsen, J. D., Krüger, J. S., Sandager-Nielsen, K., Novellino, E., Campiani, G. & Gemma, S., 7 Nov 2014, In : Journal of Medicinal Chemistry. 57, 22, p. 9578-97

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Transient inactivation of the ventral hippocampus in neonatal rats impairs the mesolimbic regulation of prefrontal glutamate release in adulthood

    Bortz, D. M., Jorgensen, C. V., Mikkelsen, J. D. & Bruno, J. P., Sep 2014, In : Neuropharmacology. 84, p. 19-30 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Changes in RFamide related peptide-1 (RFRP-1)-immunoreactivity during postnatal development and the estrous cycle

    Jørgensen, S. R., Andersen, M. D., Overgaard, A. & Mikkelsen, J. D., 21 Aug 2014, In : Endocrinology. 155, 11, p. 4402-10

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Photoperiodic co-regulation of kisseptin, neurokinin B and dynorphin in the hypothalamus of a seasonal rodent

    Bartzen-Sprauer, J., Klosen, P., Ciofi, P., Mikkelsen, J. D. & Simonneaux, V., Aug 2014, In : Journal of Neuroendocrinology. 26, 8, p. 510-20 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Disparate changes in kisspeptin and neurokinin B expression in the arcuate nucleus following sex steroid manipulation reveal differential regulation of the two KNDy peptides in rats

    Overgaard, A., Ruiz-Pino, F., Castellano, J. M., Tena-Sempere, M. & Mikkelsen, J. D., 22 Jul 2014, In : Endocrinology. 155, 10, p. 3945-55

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    5-HT(2A) and mGlu2 receptor binding levels are related to differences in impulsive behavior in the Roman Low- (RLA) and High- (RHA) avoidance rat strains

    Klein, A. B., Ultved, L., Adamsen, D., Santini, M. A., Tobeña, A., Fernandez-Teruel, A., Flores, P., Moreno, M., Cardona, D., Knudsen, G. M., Aznar, S. & Mikkelsen, J. D., 28 Mar 2014, In : Neuroscience. 263, p. 36-45 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    D-serine deficiency attenuates the behavioral and cellular effects induced by the hallucinogenic 5-HT2A receptor agonist DOI

    Santini, M. A., Balu, D. T., Puhl, M. D., Hill-Smith, T. E., Berg, A. R., Lucki, I., Mikkelsen, J. D. & Coyle, J. T., 2014, In : Behavioural Brain Research. 259, p. 242-46

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Expression of the Ly-6 family proteins Lynx1 and Ly6H in the rat brain is compartmentalized, cell-type specific, and developmentally regulated

    Thomsen, M. S., Cinar, B., Jensen, M. M., Lyukmanova, E. N., Shulepko, M. A., Tsetlin, V., Klein, A. B. & Mikkelsen, J. D., 2014, In : Brain structure & function. 219, p. 1923-34

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2013
  44. Published

    Localized infusions of the partial alpha 7 nicotinic receptor agonist SSR180711 evoke rapid and transient increases in prefrontal glutamate release

    Bortz, D. M., Mikkelsen, J. D. & Bruno, J. P., 26 Dec 2013, In : Neuroscience. 255, p. 55-67 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Effect of a postnatal high-fat diet exposure on puberty onset, estrous cycle regularity, and kisspeptin expression in female rats

    Lie, M. E. K., Overgaard, A. & Mikkelsen, J. D., Dec 2013, In : Reproductive biology. 13, 4, p. 298-308 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published
  47. Published

    Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice

    Jørgensen, C. V., Jacobsen, J. P., Caron, M. G., Klein, A. B., Knudsen, G. M. & Mikkelsen, J. D., 17 Sep 2013, In : Neuroscience Letters. 555, p. 118-22

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Tesofensine induces appetite suppression and weight loss with reversal of low forebrain dopamine levels in the diet-induced obese rat

    Hansen, H. H., Jensen, M. M., Overgaard, A., Weikop, P. & Mikkelsen, J. D., 7 Aug 2013, In : Pharmacology, Biochemistry and Behavior. 110C, p. 265-271 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Gonadotropin-inhibitory hormone reduces sexual motivation but not lordosis behavior in female Syrian hamsters (Mesocricetus auratus)

    Piekarski, D. J., Zhao, S., Jennings, K. J., Iwasa, T., Legan, S. J., Mikkelsen, J. D., Tsutsui, K. & Kriegsfeld, L. J., Aug 2013, In : Hormones and Behavior. 64, 3, p. 501-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Comparative analysis of kisspeptin-immunoreactivity reveals genuine differences in the hypothalamic Kiss1 systems between rats and mice

    Overgaard, A., Tena-Sempere, M., Franceschini, I., Desroziers, E., Simonneaux, V. & Mikkelsen, J. D., Jul 2013, In : Peptides. 45, p. 85-90 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published
  52. Published

    The effect of perinatal exposure to ethinyl oestradiol or a mixture of endocrine disrupting pesticides on kisspeptin neurons in the rat hypothalamus

    Overgaard, A., Holst, K., Mandrup, K., Boberg, J., Christiansen, S., Jacobsen, A. P., Hass, U. & Mikkelsen, J. D., Jul 2013, In : NeuroToxicology. 37, p. 154-62 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Increased serum brain-derived neurotrophic factor (BDNF) levels in patients with narcolepsy

    Klein, A. B., Jennum, P., Knudsen, S., Gammeltoft, S. & Mikkelsen, J. D., 7 Jun 2013, In : Neuroscience Letters. 544, p. 31-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Distribution and seasonal variation in hypothalamic RF-amide peptides in a semi-desert rodent, the jerboa

    Janati, A., Talbi, R., Klosen, P., Mikkelsen, J. D., Magoul, R., Simonneaux, V. & El Ouezzani, S., Apr 2013, In : Journal of Neuroendocrinology. 25, 4, p. 402-11 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published
  56. Published

    Klinisk neurobiologi

    Knudsen, G. M., Mikkelsen, J. D., Paulson, O. B. & Svarer, C., 2013, Neurologi i 100 år: beretninger fra Rigshospitalets neurologiske afdeling. Paulson, OB., Thage, O. & Waldemar, G. (eds.). [Nationalt Videnscenter for Demens], p. 134-143

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

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